RA0399

antibody from Oursmab

Targeting: IL6 BSF2, HGF, HSF, IFNB2, IL-6

Immunocytochemistry

Flow cytometry

Functional assay

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Validation data

Product number: RA0399 - Provider product page
Provider: Oursmab
Product name: Clazakizumab (Biosimilar Reference Antibody) (IL6)
Antibody type: Monoclonal
Description: Clazakizumab is an investigational fully human monoclonal antibody developed as a targeted therapy for antibody-mediated rejection (AMR) in organ transplant recipients, particularly those who have undergone kidney transplantation. It is designed to modulate a specific inflammatory pathway that drives the immune system's attack against the transplanted organ. Clinical trials are evaluating its efficacy in treating chronic active AMR, a condition with limited therapeutic options that often leads to graft loss. The drug has received Breakthrough Therapy Designation from the U.S. FDA for this indication, highlighting its potential to address a serious unmet medical need.
Reactivity: Human
Isotype: IgG
Vial size: 100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
Concentration: Bottled at the concentration indicated on the vial.
Storage: Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

IL6 protein structure - RA0399 shown in red.