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- Product number
- 66146-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- IL-6 antibody
- Antibody type
- Monoclonal
- Description
- IL-6 antibody (Cat. #66146-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1A3B4
- Vial size
- 20ul, 150ul
Submitted references Synthesis and biological evaluation of novel schisanhenol derivatives as potential hepatoprotective agents.
Folic acid targets splenic extramedullary hemopoiesis to attenuate carbon black-induced coagulation-thrombosis potential.
The Transcription Factor C/EBPβ Promotes HFL-1 Cell Migration, Proliferation, and Inflammation by Activating lncRNA HAS2-AS1 in Hypoxia.
PAK1 Silencing Attenuated Proinflammatory Macrophage Activation and Foam Cell Formation by Increasing PPARγ Expression.
TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38-/- Sepsis Mice.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy.
A novel indazole derivative, compound Cyy-272, attenuates LPS-induced acute lung injury by inhibiting JNK phosphorylation.
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2.
EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response.
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1.
Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.
Follicle-stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation.
Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D.
Damage to the blood‑brain barrier and activation of neuroinflammation by focal cerebral ischemia under hyperglycemic condition.
Suppression of adenosine A2a receptors alleviates bladder overactivity and hyperalgesia in cyclophosphamide-induced cystitis by inhibiting TRPV1.
Catalytically potent and selective clusterzymes for modulation of neuroinflammation through single-atom substitutions.
Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction.
Polystyrene microplastics induced male reproductive toxicity in mice.
Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in goat male germline stem cells.
Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.
Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis.
Cardamonin inhibits LPS-induced inflammatory responses and prevents acute lung injury by targeting myeloid differentiation factor 2.
Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation.
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation.
Platelet membrane-camouflaged silver metal-organic framework drug system against infections caused by methicillin-resistant Staphylococcus aureus.
Melatonin prevents diabetes-associated cognitive dysfunction from microglia-mediated neuroinflammation by activating autophagy via TLR4/Akt/mTOR pathway.
Silencing lncRNA TUG1 Alleviates LPS-Induced Mouse Hepatocyte Inflammation by Targeting miR-140/TNF.
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Role of Endoplasmic Reticulum Stress in Otitis Media.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
The USP14-NLRC5 pathway inhibits titanium particle-induced osteolysis in mice by suppressing NF-κB and PI3K/AKT activities.
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Wu-Mei-Wan prevents high-fat diet-induced obesity by reducing white adipose tissue and enhancing brown adipose tissue function.
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos.
Silencing of lncRNA MIAT alleviates LPS-induced pneumonia via regulating miR-147a/NKAP/NF-κB axis.
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.
Inhibition of the mitochondrial complex-1 protects against carbon tetrachloride-induced acute liver injury.
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Clinicopathological significance of overexpression of interleukin-6 in colorectal cancer.
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Deng L, Cheng S, Li J, Xu X, Hao X, Fan Y, Mu S
European journal of medicinal chemistry 2022 Jan 5;227:113919
European journal of medicinal chemistry 2022 Jan 5;227:113919
Folic acid targets splenic extramedullary hemopoiesis to attenuate carbon black-induced coagulation-thrombosis potential.
Meng Q, Li B, Huang N, Wei S, Ren Q, Wu S, Li X, Chen R
Journal of hazardous materials 2022 Feb 15;424(Pt B):127354
Journal of hazardous materials 2022 Feb 15;424(Pt B):127354
The Transcription Factor C/EBPβ Promotes HFL-1 Cell Migration, Proliferation, and Inflammation by Activating lncRNA HAS2-AS1 in Hypoxia.
Yang X, Qi F, Wei S, Lin L, Liu X
Frontiers in cell and developmental biology 2021;9:651913
Frontiers in cell and developmental biology 2021;9:651913
PAK1 Silencing Attenuated Proinflammatory Macrophage Activation and Foam Cell Formation by Increasing PPARγ Expression.
Cheng WL, Zhang Q, Li B, Cao JL, Jiao L, Chao SP, Lu Z, Zhao F
Oxidative medicine and cellular longevity 2021;2021:6957900
Oxidative medicine and cellular longevity 2021;2021:6957900
TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38-/- Sepsis Mice.
Zhang H, Du Y, Guo Y, Wang Z, Li H, Lv Z, Zeng L, Chen Y, Xie Z, Li R
Journal of immunology research 2021;2021:6687555
Journal of immunology research 2021;2021:6687555
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Xin Y, Shang X, Sun X, Liu Y, Xu G, Xue G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
Qu L, Lin X, Liu C, Ke C, Zhou Z, Xu K, Cao G, Liu Y
Frontiers in pharmacology 2021;12:665376
Frontiers in pharmacology 2021;12:665376
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Yang R, Zhao Q, Rao J, Zeng F, Yuan S, Ji M, Sun X, Li J, Yang J, Cui J, Jin Z, Liu L, Liu Z
Frontiers in microbiology 2021;12:654709
Frontiers in microbiology 2021;12:654709
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Sheng S, Zou M, Yang Y, Guan M, Ren S, Wang X, Wang L, Xue Y
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2021 Sep 1;
Journal of applied microbiology 2021 Sep 1;
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Li L, Liu S, Zhou Y, Zhao M, Wang Y, Wang C, Lou P, Huang R, Ma L, Lu Y, Fu P, Liu J
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy.
Zhu J, Xin M, Xu C, He Y, Zhang W, Wang Z, Zhuang C
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3193-3205
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3193-3205
A novel indazole derivative, compound Cyy-272, attenuates LPS-induced acute lung injury by inhibiting JNK phosphorylation.
Liu Q, Yan H, Zheng X, Fu L, Bao Y, Zheng H, Liu Z, Zhang X, Chen G
Toxicology and applied pharmacology 2021 Oct 1;428:115648
Toxicology and applied pharmacology 2021 Oct 1;428:115648
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Kitayama K, Kawamoto T, Kawakami Y, Hara H, Takemori T, Fujiwara S, Yahiro S, Miyamoto T, Mifune Y, Hoshino Y, Kakutani K, Matsumoto T, Matsushita T, Niikura T, Kuroda R, Akisue T
International journal of oncology 2021 Nov;59(5)
International journal of oncology 2021 Nov;59(5)
Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2.
Luo W, Yang LB, Qian CC, Ma B, Manjengwa GM, Miao XM, Wang J, Hu CH, Jin B, Zhang LX, Zheng C, Liang G, Wang Y
Acta pharmacologica Sinica 2021 Nov 4;
Acta pharmacologica Sinica 2021 Nov 4;
EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response.
Wang M, Zhong H, Zhang X, Huang X, Wang J, Li Z, Chen M, Xiao Z
Scientific reports 2021 May 26;11(1):11014
Scientific reports 2021 May 26;11(1):11014
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Yao H, Shen H, Yu H, Wang C, Ding R, Lan X, Tash D, Wu X, Wang X, Zhang G
Physiology & behavior 2021 May 15;234:113387
Physiology & behavior 2021 May 15;234:113387
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Zhong H, Zhou Z, Guo L, Liu F, Zheng B, Bi S, Tian C
Mechanisms of ageing and development 2021 Mar;194:111417
Mechanisms of ageing and development 2021 Mar;194:111417
Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1.
Yang M, Cui Y, Song J, Cui C, Wang L, Liang K, Wang C, Sha S, He Q, Hu H, Guo X, Zang N, Sun L, Chen L
Biochemical and biophysical research communications 2021 Mar 26;546:74-82
Biochemical and biophysical research communications 2021 Mar 26;546:74-82
Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.
Li D, Liu M, Li Z, Zheng G, Chen A, Zhao L, Yang P, Wei L, Chen Y, Ruan XZ
Aging and disease 2021 Jun;12(3):747-763
Aging and disease 2021 Jun;12(3):747-763
Follicle-stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation.
Huan Z, Wang Y, Zhang M, Zhang X, Liu Y, Kong L, Xu J
FEBS open bio 2021 Jun 27;
FEBS open bio 2021 Jun 27;
Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D.
Liu X, Li T, Liu Y, Sun S, Liu D
Toxicology 2021 Jun 15;457:152820
Toxicology 2021 Jun 15;457:152820
Damage to the blood‑brain barrier and activation of neuroinflammation by focal cerebral ischemia under hyperglycemic condition.
Guo Y, Dong L, Gong A, Zhang J, Jing L, Ding T, Li PA, Zhang JZ
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Suppression of adenosine A2a receptors alleviates bladder overactivity and hyperalgesia in cyclophosphamide-induced cystitis by inhibiting TRPV1.
Yang Y, Zhang H, Lu Q, Liu X, Fan Y, Zhu J, Sun B, Zhao J, Dong X, Li L
Biochemical pharmacology 2021 Jan;183:114340
Biochemical pharmacology 2021 Jan;183:114340
Catalytically potent and selective clusterzymes for modulation of neuroinflammation through single-atom substitutions.
Liu H, Li Y, Sun S, Xin Q, Liu S, Mu X, Yuan X, Chen K, Wang H, Varga K, Mi W, Yang J, Zhang XD
Nature communications 2021 Jan 7;12(1):114
Nature communications 2021 Jan 7;12(1):114
Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction.
Cai G, Cai G, Zhou H, Zhuang Z, Liu K, Pei S, Wang Y, Wang H, Wang X, Xu S, Cui C, Sun M, Guo S, Jia K, Wang X, Zhang D
Stem cell research & therapy 2021 Jan 6;12(1):2
Stem cell research & therapy 2021 Jan 6;12(1):2
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in goat male germline stem cells.
Wei YD, Du XM, Yang DH, Ma FL, Yu XW, Zhang MF, Li N, Peng S, Liao MZ, Li GP, Bai CL, Liu WS, Hua JL
Zoological research 2021 Jan 18;42(1):14-27
Zoological research 2021 Jan 18;42(1):14-27
Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.
Cai GL, Yang ZX, Guo DY, Hu CB, Yan ML, Yan J
Scientific reports 2021 Feb 3;11(1):2918
Scientific reports 2021 Feb 3;11(1):2918
Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis.
Han Z, Wang H, Guo D, Zhang J
Aging 2021 Feb 1;13(4):5087-5103
Aging 2021 Feb 1;13(4):5087-5103
Cardamonin inhibits LPS-induced inflammatory responses and prevents acute lung injury by targeting myeloid differentiation factor 2.
Yang L, Luo W, Zhang Q, Hong S, Wang Y, Samorodov AV, Chattipakorn N, Pavlov VN, Liang G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153785
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153785
Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation.
Yang HL, Li MM, Zhou MF, Xu HS, Huan F, Liu N, Gao R, Wang J, Zhang N, Jiang L
Inflammation 2021 Dec;44(6):2448-2462
Inflammation 2021 Dec;44(6):2448-2462
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.
Yan M, Han M, Yang X, Shen R, Wang H, Zhang L, Xia S, Yang P, Zhai G, Shao Q
Journal of enzyme inhibition and medicinal chemistry 2021 Dec;36(1):1905-1915
Journal of enzyme inhibition and medicinal chemistry 2021 Dec;36(1):1905-1915
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
Qian K, Yuan L, Wang S, Kuang Y, Jin Q, Long D, Jiang Y, Zhao H, Liu K, Yao H
Clinical and experimental immunology 2021 Aug;205(2):246-256
Clinical and experimental immunology 2021 Aug;205(2):246-256
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation.
Yang Z, Chen Z, Wang C, Huang P, Luo M, Zhou R
Cytokine 2021 Aug;144:155535
Cytokine 2021 Aug;144:155535
Platelet membrane-camouflaged silver metal-organic framework drug system against infections caused by methicillin-resistant Staphylococcus aureus.
Huang R, Cai GQ, Li J, Li XS, Liu HT, Shang XL, Zhou JD, Nie XM, Gui R
Journal of nanobiotechnology 2021 Aug 4;19(1):229
Journal of nanobiotechnology 2021 Aug 4;19(1):229
Melatonin prevents diabetes-associated cognitive dysfunction from microglia-mediated neuroinflammation by activating autophagy via TLR4/Akt/mTOR pathway.
Cui Y, Yang M, Wang Y, Ren J, Lin P, Cui C, Song J, He Q, Hu H, Wang K, Sun Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21485
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21485
Silencing lncRNA TUG1 Alleviates LPS-Induced Mouse Hepatocyte Inflammation by Targeting miR-140/TNF.
Liu QM, Liu LL, Li XD, Tian P, Xu H, Li ZL, Wang LK
Frontiers in cell and developmental biology 2020;8:616416
Frontiers in cell and developmental biology 2020;8:616416
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Fang Y, Li F, Qi C, Mao X, Wang F, Zhao Z, Chen JK, Zhang Z, Wu H
Cell death discovery 2020;6:52
Cell death discovery 2020;6:52
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Zhang S, Wang H, Liu Y, Yang W, Liu J, Han Y, Liu Y, Liu F, Sun L, Xiao L
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Cawthon CR, Kirkland RA, Pandya S, Brinson NA, de La Serre CB
Physiology & behavior 2020 Nov 1;226:113124
Physiology & behavior 2020 Nov 1;226:113124
The USP14-NLRC5 pathway inhibits titanium particle-induced osteolysis in mice by suppressing NF-κB and PI3K/AKT activities.
Fang G, Fu Y, Li S, Qiu J, Kuang M, Lin S, Li C, Ding Y
The Journal of biological chemistry 2020 May 15;295(20):7018-7032
The Journal of biological chemistry 2020 May 15;295(20):7018-7032
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Zhou S, Zhou Y, Yu J, Du Y, Tan Y, Ke Y, Wang J, Han B, Ge F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Wu-Mei-Wan prevents high-fat diet-induced obesity by reducing white adipose tissue and enhancing brown adipose tissue function.
Wu F, Yang X, Hu M, Shao Q, Fang K, Li J, Zhao Y, Xu L, Zou X, Lu F, Chen G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jun 3;76:153258
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jun 3;76:153258
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
He Y, Li W, Wang Y, Tian Y, Chen X, Wu Z, Lan T, Li Y, Bai M, Liu J, Cheng K, Xie P
Journal of affective disorders 2020 Jun 15;271:262-271
Journal of affective disorders 2020 Jun 15;271:262-271
A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos.
Zhang Z, Hou WB, Zhang C, Tan YE, Zhang DD, An W, Pan SW, Wu WD, Chen QC, Xu HM
Journal of cellular and molecular medicine 2020 Dec;24(24):14217-14230
Journal of cellular and molecular medicine 2020 Dec;24(24):14217-14230
Silencing of lncRNA MIAT alleviates LPS-induced pneumonia via regulating miR-147a/NKAP/NF-κB axis.
Liu M, Li W, Song F, Zhang L, Sun X
Aging 2020 Dec 9;13(2):2506-2518
Aging 2020 Dec 9;13(2):2506-2518
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D
Life sciences 2020 Aug 15;255:117719
Life sciences 2020 Aug 15;255:117719
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Yang K, Lu T, Zhan L, Zhou C, Zhang N, Lei S, Wang Y, Yang J, Yan M, Lv G, Chen S
International journal of biological macromolecules 2020 Apr 15;149:320-330
International journal of biological macromolecules 2020 Apr 15;149:320-330
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, Zheng T, Pu S, Xia X, Fu W
Oxidative medicine and cellular longevity 2019;2019:3765898
Oxidative medicine and cellular longevity 2019;2019:3765898
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.
Qiu JG, Wang L, Liu WJ, Wang JF, Zhao EJ, Zhou FM, Ji XB, Wang LH, Xia ZK, Wang W, Lin MC, Liu LZ, Huang YX, Jiang BH
Frontiers in pharmacology 2019;10:1002
Frontiers in pharmacology 2019;10:1002
Inhibition of the mitochondrial complex-1 protects against carbon tetrachloride-induced acute liver injury.
Hua H, Zhang Z, Qian Y, Yuan H, Ge W, Huang S, Zhang A, Zhang Y, Jia Z, Ding G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108948
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108948
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Han J, Guo D, Sun XY, Wang JM, Ouyang JM, Gui BS
Scientific reports 2019 Jul 8;9(1):9871
Scientific reports 2019 Jul 8;9(1):9871
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Clinicopathological significance of overexpression of interleukin-6 in colorectal cancer.
Zeng J, Tang ZH, Liu S, Guo SS
World journal of gastroenterology 2017 Mar 14;23(10):1780-1786
World journal of gastroenterology 2017 Mar 14;23(10):1780-1786
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Wu YH, Liu W, Xue B, Zhang L, Liu XY, Liu B, Wang Y, Cai Y, Duan R
DNA and cell biology 2016 Dec;35(12):853-860
DNA and cell biology 2016 Dec;35(12):853-860
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Recombinant protein were subjected to SDS PAGE followed by western blot with 66146-1-Ig(IL6 antibody) at dilution of 1:10000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IL-6 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human IL-6. This antibody recognizes human antigen. The IL-6 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
