Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 66192-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- ERK1/2 antibody
- Antibody type
- Monoclonal
- Description
- ERK1/2 antibody (Cat. #66192-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4G8A11
- Vial size
- 20ul, 150ul
Submitted references Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Anti-thrombotic effects mediated by dihydromyricetin involve both platelet inhibition and endothelial protection.
DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways.
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Preferential Small Intestine Homing and Persistence of CD8 T Cells in Rhesus Macaques Achieved by Molecularly Engineered Expression of CCR9 and Reduced Ex Vivo Manipulation.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
mGluR5/ERK signaling regulated the phosphorylation and function of glycine receptor α1ins subunit in spinal dorsal horn of mice.
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin-Axin2-GSK3β Signaling Pathway.
RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR.
Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface.
CXCR5-Dependent Entry of CD8 T Cells into Rhesus Macaque B-Cell Follicles Achieved through T-Cell Engineering.
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Amphiregulin mediates hCG-induced StAR expression and progesterone production in human granulosa cells.
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop.
Wang C, Wang X, Han A, Wang Y, Jiang H
Experimental and therapeutic medicine 2021 May;21(5):470
Experimental and therapeutic medicine 2021 May;21(5):470
Anti-thrombotic effects mediated by dihydromyricetin involve both platelet inhibition and endothelial protection.
Chen S, Lv K, Sharda A, Deng J, Zeng W, Zhang C, Hu Q, Jin P, Yao G, Xu X, Ming Z, Fang C
Pharmacological research 2021 May;167:105540
Pharmacological research 2021 May;167:105540
DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.
Wang X, Wang HY, Hu GS, Tang WS, Weng L, Zhang Y, Guo H, Yao SS, Liu SY, Zhang GL, Han Y, Liu M, Zhang XD, Cen X, Shen HF, Xiao N, Liu CQ, Wang HR, Huang J, Liu W, Li P, Zhao TJ
Cell reports 2021 Jun 22;35(12):109281
Cell reports 2021 Jun 22;35(12):109281
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways.
Dou Z, Gao L, Ren W, Zhang H, Wang X, Li S, Zheng J, Kong X, Chi P, Zhi K
Experimental cell research 2020 Nov 15;396(2):112290
Experimental cell research 2020 Nov 15;396(2):112290
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
Ding H, Song Y, Huang X, Wang L, Luo S, Zhang H, Pan H, Jiang W, Qian J, Yao G, Wen L, Zhang Y
Biomaterials science 2020 Jul 28;8(15):4358-4369
Biomaterials science 2020 Jul 28;8(15):4358-4369
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
Yang ZY, Yang L, Xu CW, Wang XJ, Lei L
Biology open 2020 Jan 24;9(1)
Biology open 2020 Jan 24;9(1)
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Chen X, Ji S, Si J, Zhang X, Wang X, Guo Y, Zou X
Molecular medicine reports 2020 Dec;22(6):5243-5250
Molecular medicine reports 2020 Dec;22(6):5243-5250
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Preferential Small Intestine Homing and Persistence of CD8 T Cells in Rhesus Macaques Achieved by Molecularly Engineered Expression of CCR9 and Reduced Ex Vivo Manipulation.
Trivett MT, Burke JD, Deleage C, Coren LV, Hill BJ, Jain S, Barsov EV, Breed MW, Kramer JA, Del Prete GQ, Lifson JD, Swanstrom AE, Ott DE
Journal of virology 2019 Nov 1;93(21)
Journal of virology 2019 Nov 1;93(21)
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
mGluR5/ERK signaling regulated the phosphorylation and function of glycine receptor α1ins subunit in spinal dorsal horn of mice.
Zhang ZY, Bai HH, Guo Z, Li HL, He YT, Duan XL, Suo ZW, Yang X, He YX, Hu XD
PLoS biology 2019 Aug;17(8):e3000371
PLoS biology 2019 Aug;17(8):e3000371
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Wang AL, Li Y, Zhao Q, Fan LQ
Molecular medicine reports 2018 Jun;17(6):7721-7729
Molecular medicine reports 2018 Jun;17(6):7721-7729
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin-Axin2-GSK3β Signaling Pathway.
Xie YY, Mo CL, Cai YH, Wang WJ, Hong XX, Zhang KK, Liu QF, Liu YJ, Hong JJ, He T, Zheng ZZ, Mo W, Li BA
Diabetes 2018 Dec;67(12):2569-2584
Diabetes 2018 Dec;67(12):2569-2584
RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR.
Li H, Al-Japairai K, Tao Y, Xiang Z
Oncotarget 2017 Sep 22;8(42):72633-72651
Oncotarget 2017 Sep 22;8(42):72633-72651
Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface.
Perconti G, Maranto C, Romancino DP, Rubino P, Feo S, Bongiovanni A, Giallongo A
Scientific reports 2017 Jun 19;7(1):3841
Scientific reports 2017 Jun 19;7(1):3841
CXCR5-Dependent Entry of CD8 T Cells into Rhesus Macaque B-Cell Follicles Achieved through T-Cell Engineering.
Ayala VI, Deleage C, Trivett MT, Jain S, Coren LV, Breed MW, Kramer JA, Thomas JA, Estes JD, Lifson JD, Ott DE
Journal of virology 2017 Jun 1;91(11)
Journal of virology 2017 Jun 1;91(11)
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Chen B, Liu J, Ho TT, Ding X, Mo YY
Oncogenesis 2016 Dec 12;5(12):e279
Oncogenesis 2016 Dec 12;5(12):e279
Amphiregulin mediates hCG-induced StAR expression and progesterone production in human granulosa cells.
Fang L, Yu Y, Zhang R, He J, Sun YP
Scientific reports 2016 Apr 26;6:24917
Scientific reports 2016 Apr 26;6:24917
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, Peng K, Wang W, Xiao W, Yang H
International journal of biological sciences 2015;11(6):664-71
International journal of biological sciences 2015;11(6):664-71
miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop.
Guan X, Gao Y, Zhou J, Wang J, Zheng F, Guo F, Chang A, Li X, Wang B
Stem cells (Dayton, Ohio) 2015 May;33(5):1589-600
Stem cells (Dayton, Ohio) 2015 May;33(5):1589-600
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ERK1/2 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human ERK1/2. This antibody recognizes human, mouse antigen. The ERK1/2 antibody has been validated for the following applications: ELISA, WB analysis.