4695

antibody from Cell Signaling Technology, Inc

Targeting: MAPK3 ERK1, p44erk1, p44mapk, PRKM3

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

4695

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#4695, RRID:AB_390779

Product name

p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat, Bovine, Canine, Drosophila, Hamster, Porcine, Simian, Other

Host

Rabbit

Storage

-20°C

References

Submitted references

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PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes.

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BMC immunology 2010 Oct 28;11:53

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The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway.

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Nature immunology 2010 Jun;11(6):487-94

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Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear localization is dependent on docking domain interactions.

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Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling.

Kang L, Zhang X, Xie Y, Tu Y, Wang D, Liu Z, Wang ZY
Molecular endocrinology (Baltimore, Md.) 2010 Apr;24(4):709-21

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Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.

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Erk1/2 MAP kinases are required for epidermal G2/M progression.

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The Journal of cell biology 2009 May 4;185(3):409-22

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Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice.

Miyaji M, Kortum RL, Surana R, Li W, Woolard KD, Simpson RM, Samelson LE, Sommers CL
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 25;106(34):14502-7

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Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.

Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, Solow-Cordero DE, Jiang J, Rowitch DH, Chen JK
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 18;106(33):14132-7

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Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver.

Gray MJ, Van Buren G, Dallas NA, Xia L, Wang X, Yang AD, Somcio RJ, Lin YG, Lim S, Fan F, Mangala LS, Arumugam T, Logsdon CD, Lopez-Berestein G, Sood AK, Ellis LM
Journal of the National Cancer Institute 2008 Jan 16;100(2):109-20

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.

Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK
Nature medicine 2008 Dec;14(12):1351-6

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The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.

Rygiel TP, Mertens AE, Strumane K, van der Kammen R, Collard JG
Journal of cell science 2008 Apr 15;121(Pt 8):1183-92