GABRA2

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Description

gamma-aminobutyric acid type A receptor alpha2 subunit

Protein family

FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

4:p12 (46248427 - 46475230)

Ensembl ID

ENSG00000151834  (ver. 98.38)

Orthologs

Mouse Gabra2: ENSMUSG00000000560

UniProt

P47869

neXtProt

NX_P47869

Human splice variants
Mouse splice variants