10655-1-AP

antibody from Proteintech Group

Targeting: FKBP4 FKBP52, FKBP59

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

10655-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10655-1-AP, RRID:AB_2246853

Product name

FKBP52 antibody

Antibody type

Polyclonal

Description

KD/KO validated FKBP52 antibody (Cat. #10655-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations.

Kojima R, Paslawski W, Lyu G, Arenas E, Zhang X, Svenningsson P
International journal of molecular sciences 2024 Jan 4;25(1)

---

Chlorogenic Acid Alleviated AFB1-Induced Hepatotoxicity by Regulating Mitochondrial Function, Activating Nrf2/HO-1, and Inhibiting Noncanonical NF-κB Signaling Pathway.

Wang Q, Liu T, Koci M, Wang Y, Fu Y, Ma M, Ma Q, Zhao L
Antioxidants (Basel, Switzerland) 2023 Nov 22;12(12)

---

Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.

He Y, Zheng CC, Yang J, Li SJ, Xu TY, Wei X, Chen WY, Jiang ZL, Xu JJ, Zhang GG, Cheng C, Chen KS, Shi XY, Qin DJ, Liu JB, Li B
Cell discovery 2023 Jul 18;9(1):74

---

A Study on the Pharmacological Effects and Mechanism of Rhodojaponin III in Rheumatoid Arthritis.

Liu X, Li S, Xu Y, Mei W, Zhou R
Frontiers in bioscience (Landmark edition) 2023 Dec 15;28(12):337

---

Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment.

Xiong H, Chen Z, Lin B, Chen W, Li Q, Li Y, Fang M, Wang Y, Zhang H, Lu Y, Bi A, Wu S, Jia Y, Wang X
Molecular therapy oncolytics 2022 Mar 17;24:371-384

---

FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells.

Maeda K, Habara M, Kawaguchi M, Matsumoto H, Hanaki S, Masaki T, Sato Y, Matsuyama H, Kunieda K, Nakagawa H, Shimada M
Molecular oncology 2022 Feb;16(4):940-956

---

The helix-loop-helix transcriptional regulator Id4 is required for terminal differentiation of luminal epithelial cells in the prostate.

Hewa Bostanthirige D, Komaragiri SK, Joshi JB, Alzahrani M, Saini I, Jain S, Bowen NJ, Havrda MC, Chaudhary J
Oncoscience 2021;8:14-30

---

Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell.

Xiong H, Chen Z, Lin B, Xie B, Liu X, Chen C, Li Z, Jia Y, Wu Z, Yang M, Jia Y, Wang L, Zhou J, Meng X
Frontiers in immunology 2021;12:745111

---

Multiple roles for peptidylglycine α-amidating monooxygenase in the response to hypoxia.

Rao VKS, Eipper BA, Mains RE
Journal of cellular physiology 2021 Nov;236(11):7745-7758

---

miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.

Chen Q, Li Z, Xu Z, Chen C, Wang J, Zhu J, Dong Z
Biological trace element research 2021 Nov;199(11):4119-4128

---

FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer.

Mangé A, Coyaud E, Desmetz C, Laurent E, Béganton B, Coopman P, Raught B, Solassol J
Theranostics 2019;9(23):7003-7015

---

Changes in Corticotrope Gene Expression Upon Increased Expression of Peptidylglycine α-Amidating Monooxygenase.

Mains RE, Blaby-Haas C, Rheaume BA, Eipper BA
Endocrinology 2018 Jul 1;159(7):2621-2639

---

Comparative proteome analysis of abdominal adipose tissues between fat and lean broilers.

Wu CY, Wu YY, Liu CD, Wang YX, Na W, Wang N, Li H
Proteome science 2016;14(1):9

---

The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly.

Martinez NJ, Chang HM, Borrajo Jde R, Gregory RI
RNA (New York, N.Y.) 2013 Nov;19(11):1583-93

---

Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders.

Soontornniyomkij V, Everall IP, Moore DJ, Gouaux B, Tatro ET, Gospodarev V, Masliah E, Yin NS, Vinters HV, Achim CL
Journal of neurovirology 2012 Aug;18(4):313-22

---

Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain.

Soontornniyomkij V, Risbrough VB, Young JW, Wallace CK, Soontornniyomkij B, Jeste DV, Achim CL
Age (Dordrecht, Netherlands) 2010 Sep;32(3):309-22

---

Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women.

Desmetz C, Bascoul-Mollevi C, Rochaix P, Lamy PJ, Kramar A, Rouanet P, Maudelonde T, Mangé A, Solassol J
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jul 15;15(14):4733-41

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HeLa cells were subjected to SDS PAGE followed by western blot with 10655-1-AP(FKBP52 antibody) at dilution of 1:1000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of MCF-7 cells, using FKBP4 antibody 10655-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunoprecipitation

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

IP Result of anti-FKBP52 (IP:10655-1-AP, 3ug; Detection:10655-1-AP 1:1000) with HeLa cells lysate 3000ug.

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human prostate cancer using 10655-1-AP(FKBP52 antibody) at dilution of 1:100 (under 25x lens)

Sample type

tissue