Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- ADI-SRA-1400-D - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-SRA-1400-D, RRID:AB_2039240
- Product name
- FKBP59, mAb (KN382/EC1)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Protein G affinity purified. Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
- Isotype
- IgG
- Antibody clone number
- KN382/EC1
Submitted references Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain.
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.
Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506.
Tsutsumi S, Mollapour M, Graf C, Lee CT, Scroggins BT, Xu W, Haslerova L, Hessling M, Konstantinova AA, Trepel JB, Panaretou B, Buchner J, Mayer MP, Prodromou C, Neckers L
Nature structural & molecular biology 2009 Nov;16(11):1141-7
Nature structural & molecular biology 2009 Nov;16(11):1141-7
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.
Guo Y, Guettouche T, Fenna M, Boellmann F, Pratt WB, Toft DO, Smith DF, Voellmy R
The Journal of biological chemistry 2001 Dec 7;276(49):45791-9
The Journal of biological chemistry 2001 Dec 7;276(49):45791-9
Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506.
Gold BG, Densmore V, Shou W, Matzuk MM, Gordon HS
The Journal of pharmacology and experimental therapeutics 1999 Jun;289(3):1202-10
The Journal of pharmacology and experimental therapeutics 1999 Jun;289(3):1202-10
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of FKBP59 mAb (KN382/EC1) (Prod. No. ADI-SRA-1400): Lane 1: MW marker, Lane 2: HeLa Cell Lysate(heat shocked), Lane 3: MDBK Celll Lysate (heat shocked), Lane 4: VERO Cell Lysate (heat shocked), Lane 5: RK-13 Cell Lysate (heat shocked).