15062-1-AP
antibody from Proteintech Group
Targeting: EXOSC3
CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p
Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15062-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15062-1-AP, RRID:AB_2278183
- Product name
- EXOSC3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EXOSC3 antibody (Cat. #15062-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner.
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
Integrator is a genome-wide attenuator of non-productive transcription.
The RNA exosome shapes the expression of key protein-coding genes.
The RNA exosome contributes to gene expression regulation during stem cell differentiation.
A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans.
Affinity Purification of the RNA Degradation Complex, the Exosome, from HEK-293 Cells.
Relationships between PROMPT and gene expression.
EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia.
Goodier JL, Wan H, Soares AO, Sanchez L, Selser JM, Pereira GC, Karma S, García-Pérez JL, Kazazian HH Jr, García Cañadas MM
PLoS genetics 2023 Jul;19(7):e1010795
PLoS genetics 2023 Jul;19(7):e1010795
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JN, Dos Santos Souza C, Zhang S, Castelli L, Hautbergue G, Azzouz M, Gordon D, Krogan N, Ferraiuolo L, Snyder MP, Shaw PJ, Rehwinkel J, Cooper-Knock J
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner.
Savoca V, Rivosecchi J, Gaiatto A, Rossi A, Mosca R, Gialdini I, Zubovic L, Tebaldi T, Macchi P, Cusanelli E
Cell reports 2023 Apr 25;42(4):112406
Cell reports 2023 Apr 25;42(4):112406
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
An H, Litscher G, Watanabe N, Wei W, Hashimoto T, Iwatsubo T, Buchman VL, Shelkovnikova TA
Neurobiology of disease 2022 Jan;162:105585
Neurobiology of disease 2022 Jan;162:105585
Integrator is a genome-wide attenuator of non-productive transcription.
Lykke-Andersen S, Žumer K, Molska EŠ, Rouvière JO, Wu G, Demel C, Schwalb B, Schmid M, Cramer P, Jensen TH
Molecular cell 2021 Feb 4;81(3):514-529.e6
Molecular cell 2021 Feb 4;81(3):514-529.e6
The RNA exosome shapes the expression of key protein-coding genes.
Wu M, Karadoulama E, Lloret-Llinares M, Rouviere JO, Vaagensø CS, Moravec M, Li B, Wang J, Wu G, Gockert M, Pelechano V, Jensen TH, Sandelin A
Nucleic acids research 2020 Sep 4;48(15):8509-8528
Nucleic acids research 2020 Sep 4;48(15):8509-8528
The RNA exosome contributes to gene expression regulation during stem cell differentiation.
Lloret-Llinares M, Karadoulama E, Chen Y, Wojenski LA, Villafano GJ, Bornholdt J, Andersson R, Core L, Sandelin A, Jensen TH
Nucleic acids research 2018 Nov 30;46(21):11502-11513
Nucleic acids research 2018 Nov 30;46(21):11502-11513
A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans.
Kalisiak K, Kuliński TM, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A
Nucleic acids research 2017 Feb 28;45(4):2068-2080
Nucleic acids research 2017 Feb 28;45(4):2068-2080
Affinity Purification of the RNA Degradation Complex, the Exosome, from HEK-293 Cells.
Domanski M, LaCava J
Bio-protocol 2017 Apr 20;7(8)
Bio-protocol 2017 Apr 20;7(8)
Relationships between PROMPT and gene expression.
Lloret-Llinares M, Mapendano CK, Martlev LH, Lykke-Andersen S, Jensen TH
RNA biology 2016;13(1):6-14
RNA biology 2016;13(1):6-14
EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia.
Boczonadi V, Müller JS, Pyle A, Munkley J, Dor T, Quartararo J, Ferrero I, Karcagi V, Giunta M, Polvikoski T, Birchall D, Princzinger A, Cinnamon Y, Lützkendorf S, Piko H, Reza M, Florez L, Santibanez-Koref M, Griffin H, Schuelke M, Elpeleg O, Kalaydjieva L, Lochmüller H, Elliott DJ, Chinnery PF, Edvardson S, Horvath R
Nature communications 2014 Jul 3;5:4287
Nature communications 2014 Jul 3;5:4287
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 15062-1-AP(EXOSC3 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EXOSC3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EXOSC3. This antibody recognizes human, mouse, rat antigen. The EXOSC3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 15062-1-AP(EXOSC3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue