HPA031763

antibody from Atlas Antibodies

Targeting: MCOLN1 ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

HPA031763

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA031763, RRID:AB_10600822

Product name

Anti-MCOLN1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human MCOLN1, Gene description: mucolipin 1, Alternative Gene Names: ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1, Validated applications: ICC, WB, Uniprot ID: Q9GZU1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system

Somogyi A, Kirkham E, Lloyd-Evans E, Winston J, Allen N, Mackrill J, Anderson K, Hawkins P, Gardiner S, Waller-Evans H, Sims R, Boland B, O'Neill C
Journal of Cell Science 2023;136(6)

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Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity.

Zhong D, Wang R, Zhang H, Wang M, Zhang X, Chen H
Nature communications 2023 Jul 6;14(1):3997

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Modulation of Lysosomal Cl(-) Mediates Migration and Apoptosis through the TRPML1 as a Lysosomal Cl(-) Sensor.

Lee D, Hong JH
Cells 2023 Jul 12;12(14)

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Acidifying Endolysosomes Prevented Low-Density Lipoprotein-Induced Amyloidogenesis

Hui L, Soliman M, Geiger N, Miller N, Afghah Z, Lakpa K, Chen X, Geiger J
Journal of Alzheimer's Disease 2019;67(1):393-410