15291-1-AP

antibody from Proteintech Group

Targeting: MCOLN1 ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1

ELISA (Data presented on provider website)

Antibody Data

Product number

15291-1-AP

Provider

Proteintech Group

Product name

MCOLN1 antibody

Antibody type

Polyclonal

Description

MCOLN1 antibody (Cat. #15291-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

TRIM7-mediated autophagy-lysosomal signaling is essential for preimplantation development in mice.

Khan S, Yan F, Li W, Guo J, Gu X, Tang Z, Bibi U, Dong X, Chen L, Yao Y, Xu J
Journal of translational medicine 2026 Mar 17;24(1)

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Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.

Chen H, Zhu M, Zhao Z, Jiang Y, Wang H, Liu Y, Chen Y, Li H, Xun C, Hui H
Pharmacological research 2025 Dec;222:108050

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Epimedokoreanin B blocks autophagic flux to inhibit progression of triple negative breast cancer through targeting MCOLN1/TRPML1 channel.

Zhao C, Zhang P, Yang X, Liu M, Guan Z, Ma B, Duan X, Su C
Free radical biology & medicine 2025 Dec 1;240:222-237

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TRPML1 ameliorates seizures-related neuronal injury by regulating autophagy and lysosomal biogenesis via Ca(2+)/TFEB signaling pathway.

Peng T, Xie Y, Zhao S, Wang X, Zhang W, Xie Y, Wang C, Xie N
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167477

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Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.

Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B
Autophagy 2023 Dec;19(12):3132-3150