Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 15560-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15560-1-AP, RRID:AB_2224162
- Product name
- ALDH1B1 antibody
- Antibody type
- Polyclonal
- Description
- ALDH1B1 antibody (Cat. #15560-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Metabolism-related ALDH1B1 acts as potential predictor and therapeutic target for primary gastrointestinal diffuse large B-cell lymphoma.
Identification and validation of glucose metabolism-related gene signature in endometrial cancer.
Lfng-expressing centroacinar cell is a unique cell-of-origin for p53 deficient pancreatic cancer.
Compression-induced NF-κB activation sustains tumor cell survival in confinement by detoxifying aldehydes and promotes metastasis.
Targeting Retinaldehyde Dehydrogenases to Enhance Temozolomide Therapy in Glioblastoma.
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids.
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis.
Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication.
Identification and experimental validation of KMO as a critical immune-associated mitochondrial gene in unstable atherosclerotic plaque.
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice.
Multi-omics and chemical profiling approaches to understand the material foundation and pharmacological mechanism of sophorae tonkinensis radix et rhizome-induced liver injury in mice.
Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.
Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation.
Aldehyde dehydrogenase 2 deficiency promotes skeletal muscle atrophy in aged mice.
Effect of different types of muscle activity on the gene and protein expression of ALDH family members in C57BL/6J mouse skeletal muscle.
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight.
Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss.
Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice.
Maternal aldehyde elimination during pregnancy preserves the fetal genome.
Qiao Q, Liu B, Shang J, Sun W, Zhou X, Fang X, Hu S, Wang X
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1482-1501
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1482-1501
Identification and validation of glucose metabolism-related gene signature in endometrial cancer.
Jiang J, Xia N, Yang M, Qiu P, Zhu W, Chen J, Zhu J
BMC cancer 2025 Jan 7;25(1):30
BMC cancer 2025 Jan 7;25(1):30
Lfng-expressing centroacinar cell is a unique cell-of-origin for p53 deficient pancreatic cancer.
Chung WC, Zhang S, Atfi A, Xu K
Oncogene 2025 Feb;44(6):348-362
Oncogene 2025 Feb;44(6):348-362
Compression-induced NF-κB activation sustains tumor cell survival in confinement by detoxifying aldehydes and promotes metastasis.
Liu B, Liu M, Zhang Y, Zhu Y, Zhou D, Gao H, Yang F, Gao D, Zhao Y, Tao B, Yao F, Yang W
Nature communications 2025 Dec 14;17(1):778
Nature communications 2025 Dec 14;17(1):778
Targeting Retinaldehyde Dehydrogenases to Enhance Temozolomide Therapy in Glioblastoma.
Jiménez R, Constantinescu A, Yazir M, Alfonso-Triguero P, Pequerul R, Parés X, Pérez-Alea M, Candiota AP, Farrés J, Lorenzo J
International journal of molecular sciences 2024 Oct 26;25(21)
International journal of molecular sciences 2024 Oct 26;25(21)
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids.
Bi G, Zhang X, Li W, Lu X, He X, Li Y, Bai R, Zhang H
Cell reports methods 2024 May 20;4(5):100778
Cell reports methods 2024 May 20;4(5):100778
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis.
Zhen J, Li Y, Zhang Y, Zhou Y, Zhao L, Huang G, Xu A
Chinese medicine 2024 Jun 15;19(1):87
Chinese medicine 2024 Jun 15;19(1):87
Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication.
Ming S, Zhang S, Xing J, Yang G, Zeng L, Wang J, Chu B
iScience 2024 Jul 19;27(7):110144
iScience 2024 Jul 19;27(7):110144
Identification and experimental validation of KMO as a critical immune-associated mitochondrial gene in unstable atherosclerotic plaque.
Liao FJ, Shen SL, Bao HL, Li H, Zhao QW, Chen L, Gong CW, Xiong CZ, Liu WP, Li W, Liu DN
Journal of translational medicine 2024 Jul 18;22(1):668
Journal of translational medicine 2024 Jul 18;22(1):668
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice.
Liu MY, Xu KH, Liu S, Xiao WJ
Molecular nutrition & food research 2024 Dec;68(23):e2400766
Molecular nutrition & food research 2024 Dec;68(23):e2400766
Multi-omics and chemical profiling approaches to understand the material foundation and pharmacological mechanism of sophorae tonkinensis radix et rhizome-induced liver injury in mice.
Rao SW, Liu CJ, Liang D, Duan YY, Chen ZH, Li JJ, Pang HQ, Zhang FX, Shi W
Journal of ethnopharmacology 2024 Aug 10;330:118224
Journal of ethnopharmacology 2024 Aug 10;330:118224
Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.
Zhou H, Wan S, Luo Y, Liu H, Jiang J, Guo Y, Xiao J, Wu B
Gastroenterology report 2023;11:goad006
Gastroenterology report 2023;11:goad006
Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation.
Cerretelli G, Zhou Y, Müller MF, Adams DJ, Arends MJ
Disease models & mechanisms 2023 Aug 1;16(8)
Disease models & mechanisms 2023 Aug 1;16(8)
Aldehyde dehydrogenase 2 deficiency promotes skeletal muscle atrophy in aged mice.
Kasai A, Jee E, Tamura Y, Kouzaki K, Kotani T, Nakazato K
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Jun 1;322(6):R511-R525
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Jun 1;322(6):R511-R525
Effect of different types of muscle activity on the gene and protein expression of ALDH family members in C57BL/6J mouse skeletal muscle.
Jee E, Tamura Y, Kouzaki K, Kotani T, Nakazato K
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Jul 1;47(7):775-786
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Jul 1;47(7):775-786
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
Zhao W, Peng D, Li W, Chen S, Liu B, Huang P, Wu J, Du B, Li P
Journal of the science of food and agriculture 2022 Dec;102(15):6877-6888
Journal of the science of food and agriculture 2022 Dec;102(15):6877-6888
β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight.
Hidalgo-Gutiérrez A, Barriocanal-Casado E, Díaz-Casado ME, González-García P, Zenezini Chiozzi R, Acuña-Castroviejo D, López LC
Biomedicines 2021 Oct 13;9(10)
Biomedicines 2021 Oct 13;9(10)
Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.
Wakabayashi Y, Tamura Y, Kouzaki K, Kikuchi N, Hiranuma K, Menuki K, Tajima T, Yamanaka Y, Sakai A, Nakayama KI, Kawamoto T, Kitagawa K, Nakazato K
American journal of physiology. Regulatory, integrative and comparative physiology 2020 Apr 1;318(4):R677-R690
American journal of physiology. Regulatory, integrative and comparative physiology 2020 Apr 1;318(4):R677-R690
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Győrffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD
eLife 2019 Sep 3;8
eLife 2019 Sep 3;8
The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss.
Müller MF, Kendall TJ, Adams DJ, Zhou Y, Arends MJ
Experimental and molecular pathology 2018 Aug;105(1):63-70
Experimental and molecular pathology 2018 Aug;105(1):63-70
Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice.
Müller MF, Zhou Y, Adams DJ, Arends MJ
The Journal of pathology 2017 Apr;241(5):649-660
The Journal of pathology 2017 Apr;241(5):649-660
Maternal aldehyde elimination during pregnancy preserves the fetal genome.
Oberbeck N, Langevin F, King G, de Wind N, Crossan GP, Patel KJ
Molecular cell 2014 Sep 18;55(6):807-817
Molecular cell 2014 Sep 18;55(6):807-817
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15560-1-AP(ALDH1B1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15560-1-AP(ALDH1B1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ALDH1B1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ALDH1B1. This antibody recognizes human,mouse,rat antigen. The ALDH1B1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
