Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 20338-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20338-1-AP, RRID:AB_10667459
- Product name
- GPNMB antibody
- Antibody type
- Polyclonal
- Description
- GPNMB antibody (Cat. #20338-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Downregulation of glycoprotein non-metastatic melanoma protein B prevents high glucose-induced angiogenesis in diabetic retinopathy.
GPNMB-Positive Cells in Head and Neck Squamous Cell Carcinoma-Their Roles in Cancer Stemness, Therapy Resistance, and Metastasis.
The anti-inflammatory and osteogenic activity of chitosan/polyvinyl alcohol/graphene oxide/astaxanthin nanofibers membranes in vitro study.
GPNMB expression identifies TSC1/2/mTOR-associated and MiT family translocation-driven renal neoplasms.
Transcriptome analysis reveals GPNMB as a potential therapeutic target for gastric cancer.
Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Ameliorates the Inflammatory Response in Periodontal Disease.
Ocular Albinism Type 1 Regulates Melanogenesis in Mouse Melanocytes.
Genomic profiling of rectal adenoma and carcinoma by array-based comparative genomic hybridization.
Qin T, Xi X, Wu Z
Molecular and cellular biochemistry 2023 Apr;478(4):697-706
Molecular and cellular biochemistry 2023 Apr;478(4):697-706
GPNMB-Positive Cells in Head and Neck Squamous Cell Carcinoma-Their Roles in Cancer Stemness, Therapy Resistance, and Metastasis.
Kawasaki Y, Suzuki H, Suzuki S, Yamada T, Suzuki M, Ito A, Hatakeyama H, Miura M, Omori Y
Pathology oncology research : POR 2022;28:1610450
Pathology oncology research : POR 2022;28:1610450
The anti-inflammatory and osteogenic activity of chitosan/polyvinyl alcohol/graphene oxide/astaxanthin nanofibers membranes in vitro study.
Dang X, Zhang H, Lin L, Li P, Ren L, Zhang W, Song R
Journal of biomaterials applications 2022 May;36(10):1873-1881
Journal of biomaterials applications 2022 May;36(10):1873-1881
GPNMB expression identifies TSC1/2/mTOR-associated and MiT family translocation-driven renal neoplasms.
Salles DC, Asrani K, Woo J, Vidotto T, Liu HB, Vidal I, Matoso A, Netto GJ, Argani P, Lotan TL
The Journal of pathology 2022 Jun;257(2):158-171
The Journal of pathology 2022 Jun;257(2):158-171
Transcriptome analysis reveals GPNMB as a potential therapeutic target for gastric cancer.
Ren F, Zhao Q, Liu B, Sun X, Tang Y, Huang H, Mei L, Yu Y, Mo H, Dong H, Zheng P, Mi Y
Journal of cellular physiology 2020 Mar;235(3):2738-2752
Journal of cellular physiology 2020 Mar;235(3):2738-2752
Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Ameliorates the Inflammatory Response in Periodontal Disease.
Song R, Lin L
Inflammation 2019 Aug;42(4):1170-1178
Inflammation 2019 Aug;42(4):1170-1178
Ocular Albinism Type 1 Regulates Melanogenesis in Mouse Melanocytes.
Chen T, Wang H, Liu Y, Zhao B, Zhao Y, Fan R, Wang P, Dong C
International journal of molecular sciences 2016 Sep 27;17(10)
International journal of molecular sciences 2016 Sep 27;17(10)
Genomic profiling of rectal adenoma and carcinoma by array-based comparative genomic hybridization.
Shi ZZ, Zhang YM, Shang L, Hao JJ, Zhang TT, Wang BS, Liang JW, Chen X, Zhang Y, Wang GQ, Wang MR, Zhang Y
BMC medical genomics 2012 Nov 16;5:52
BMC medical genomics 2012 Nov 16;5:52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 20338-1-AP( GPNMB Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 20338-1-AP(GPNMB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GPNMB antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GPNMB. This antibody recognizes human, mouse antigen. The GPNMB antibody has been validated for the following applications: ELISA, IHC, WB analysis.