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- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15131-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15131-1-AP, RRID:AB_2064405
- Product name
- ATG4B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG4B antibody (Cat. #15131-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells.
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Inhibition of MGMT-mediated autophagy suppression decreases cisplatin chemosensitivity in gastric cancer.
New Anti-Cancer Strategy to Suppress Colorectal Cancer Growth Through Inhibition of ATG4B and Lysosome Function.
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells.
p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions.
Chen L, Sun L, Dai X, Li T, Yan X, Zhang Y, Xiao H, Shen X, Huang G, Xiang W, Zhang Y, Tan D, Yang S, Nie Y, Huang X, Lian J, He F
Frontiers in cell and developmental biology 2021;9:687524
Frontiers in cell and developmental biology 2021;9:687524
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Nie L, Liu M, Chen J, Wu Q, Li Y, Yi J, Zheng X, Zhang J, Chu C, Yang J
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Wang W, Huang L, Thomas ER, Hu Y, Zeng F, Li X
Frontiers in pharmacology 2020;11:559046
Frontiers in pharmacology 2020;11:559046
Inhibition of MGMT-mediated autophagy suppression decreases cisplatin chemosensitivity in gastric cancer.
Lei Y, Tang L, Hu J, Wang S, Liu Y, Yang M, Zhang J, Tang B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109896
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109896
New Anti-Cancer Strategy to Suppress Colorectal Cancer Growth Through Inhibition of ATG4B and Lysosome Function.
Fu Y, Gu Q, Luo L, Xu J, Luo Y, Xia F, Han F, Hong L, Yin XM, Huang Z, Li M
Cancers 2020 Jun 10;12(6)
Cancers 2020 Jun 10;12(6)
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
Ni Z, Kuang L, Chen H, Xie Y, Zhang B, Ouyang J, Wu J, Zhou S, Chen L, Su N, Tan Q, Luo X, Chen B, Chen S, Yin L, Huang H, Du X, Chen L
Cell death & disease 2019 Jul 8;10(7):522
Cell death & disease 2019 Jul 8;10(7):522
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Free radical biology & medicine 2019 Jan;130:576-591
Free radical biology & medicine 2019 Jan;130:576-591
RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
Muniz-Feliciano L, Doggett TA, Zhou Z, Ferguson TA
Autophagy 2017;13(12):2072-2085
Autophagy 2017;13(12):2072-2085
HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells.
Zhang N, Wu Y, Lyu X, Li B, Yan X, Xiong H, Li X, Huang G, Zeng Y, Zhang Y, Lian J, Ni Z, He F
Cancer letters 2017 Nov 28;409:81-90
Cancer letters 2017 Nov 28;409:81-90
p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions.
Tanji K, Zhang HX, Mori F, Kakita A, Takahashi H, Wakabayashi K
Journal of neuroscience research 2012 Oct;90(10):2034-42
Journal of neuroscience research 2012 Oct;90(10):2034-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 15131-1-AP(ATG4B antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 15131-1-AP(ATG4B antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATG4B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATG4B. This antibody recognizes human,mouse,rat antigen. The ATG4B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
