Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1001948 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Bub3 antibody was raised in rabbits against a 16 amino acid peptide from near the carboxy terminus of human bub3.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Distinct chromosome segregation roles for spindle checkpoint proteins.
Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis.
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.
The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.
Warren CD, Brady DM, Johnston RC, Hanna JS, Hardwick KG, Spencer FA
Molecular biology of the cell 2002 Sep;13(9):3029-41
Molecular biology of the cell 2002 Sep;13(9):3029-41
Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis.
Kalitsis P, Earle E, Fowler KJ, Choo KH
Genes & development 2000 Sep 15;14(18):2277-82
Genes & development 2000 Sep 15;14(18):2277-82
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.
Taylor SS, Ha E, McKeon F
The Journal of cell biology 1998 Jul 13;142(1):1-11
The Journal of cell biology 1998 Jul 13;142(1):1-11
The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.
Roberts BT, Farr KA, Hoyt MA
Molecular and cellular biology 1994 Dec;14(12):8282-91
Molecular and cellular biology 1994 Dec;14(12):8282-91
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