11389-1-AP

antibody from Proteintech Group

Targeting: PSMC4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

11389-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11389-1-AP, RRID:AB_2300373

Product name

PSMC4 antibody

Antibody type

Polyclonal

Description

PSMC4 antibody (Cat. #11389-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

The role of PSMC4 in non-small cell lung cancer: implications for prognosis, diagnosis, and immune microenvironment modulation.

Zhu L, Li Y, Xu Y, Lei J
Frontiers in oncology 2025;15:1503466

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A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy.

Mauthe M, van de Beek N, Mari M, Korsten G, Nobari P, Castelino KB, de Mattos EP, Ouhida I, Dijkstra JL, Schipper-Krom S, de la Ballina LR, Mueller MR, Simonsen A, Hipp MS, Kapitein LC, Kampinga HH, Reggiori F
Nature cell biology 2025 Sep;27(9):1448-1464

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Activated mTORC1 signaling pathway aggravates cisplatin induced oxidative damage by inhibiting autophagy in mouse cochlear hair cells.

Xu NN, Wen YC, Pan J, Shu F, Qu JX, Qi XF, Tang J
Neuropharmacology 2025 Jul 1;272:110433

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The Prostaglandin E2 Receptor EP4 Promotes Vascular Neointimal Hyperplasia through Translational Control of Tenascin C via the cAPM/PKA/mTORC1/rpS6 Pathway.

Xu H, Fang B, Bao C, Mao X, Zhu C, Ye L, Liu Q, Li Y, Du C, Qi H, Zhang X, Guan Y
Cells 2022 Aug 31;11(17)

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The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.

Sahu I, Mali SM, Sulkshane P, Xu C, Rozenberg A, Morag R, Sahoo MP, Singh SK, Ding Z, Wang Y, Day S, Cong Y, Kleifeld O, Brik A, Glickman MH
Nature communications 2021 Oct 26;12(1):6173

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Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.

Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)

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Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.

Nguyen L, Montrasio F, Pattamatta A, Tusi SK, Bardhi O, Meyer KD, Hayes L, Nakamura K, Banez-Coronel M, Coyne A, Guo S, Laboissonniere LA, Gu Y, Narayanan S, Smith B, Nitsch RM, Kankel MW, Rushe M, Rothstein J, Zu T, Grimm J, Ranum LPW
Neuron 2020 Feb 19;105(4):645-662.e11

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A novel role of proteasomal β1 subunit in tumorigenesis.

Yuan F, Ma Y, You P, Lin W, Lu H, Yu Y, Wang X, Jiang J, Yang P, Ma Q, Tao T
Bioscience reports 2013 Jul 16;33(4)

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11389-1-AP(PSMC4 antibody) at dilution of 1:500

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using PSMC4 antibody 11389-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon cancer using 11389-1-AP(PSMC4 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue