abx317153

antibody from Abbexa
Targeting: PSMC4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7
Provider product page for abx317153
No application information provided.

Antibody data

Product number
abx317153 - Provider product page
Provider
Abbexa
Product name
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody (HRP)
Antibody type
Polyclonal
Description
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody (HRP) is a Rabbit Polyclonal against 26S Proteasome Regulatory Subunit 6B (PSMC4) conjugated to HRP. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Reactivity
Human
Host
Rabbit
Conjugate
Horseradish Peroxidase
Isotype
IgG
Vial size
100 µg
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
PSMC4 protein structure - abx317153 shown in red.