abx317155

antibody from Abbexa

Targeting: PSMC4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7

No application information provided.

Antibody Data

Product number

abx317155

Provider

Abbexa

Product name

26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody (Biotin)

Antibody type

Polyclonal

Description

26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody (Biotin) is a Rabbit Polyclonal against 26S Proteasome Regulatory Subunit 6B (PSMC4) conjugated to Biotin. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Reactivity

Human

Host

Rabbit

Conjugate

Biotin

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.