14048-1-AP
antibody from Proteintech Group
Targeting: SLC27A2
ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS
Antibody data
- Antibody Data
- Antigen structure
- References [34]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 14048-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14048-1-AP, RRID:AB_2239416
- Product name
- FATP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FATP2 antibody (Cat. #14048-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation.
Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice.
Hepatotoxicity induced in rats by chronic exposure to F-53B, an emerging replacement of perfluorooctane sulfonate (PFOS).
Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment.
Key enzyme in charge of ketone reabsorption of renal tubular SMCT1 may be a new target in diabetic kidney disease.
Dynamic cellular changes in acute kidney injury caused by different ischemia time.
Letter to the editor: Adipose lipolysis is important for ethanol to induce fatty liver in the NIAAA murine model of chronic and binge ethanol feeding.
Adipose lipolysis is important for ethanol to induce fatty liver in the National Institute on Alcohol Abuse and Alcoholism murine model of chronic and binge ethanol feeding.
FATP2 regulates non-small cell lung cancer by mediating lipid metabolism through ACSL1.
Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease.
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate.
Icariin Alleviates Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome by Improving Liver Fatty Acid Oxidation and Inhibiting Lipid Accumulation.
Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice.
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway.
Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol.
Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice.
DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic Steatosis.
Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes.
Ameliorative Effect of Ethanolic Echinacea purpurea against Hyperthyroidism-Induced Oxidative Stress via AMRK and PPAR Signal Pathway Using Transcriptomics and Network Pharmacology Analysis.
Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis.
B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36.
Sperm acquire epididymis-derived proteins through epididymosomes.
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity.
MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Orphan nuclear receptor NR4A1 suppresses hyperhomocysteinemia-induced hepatic steatosis in vitro and in vivo.
Rapid affinity purification of intracellular organelles using a twin strep tag.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Real-Time Tracking of BODIPY-C12 Long-Chain Fatty Acid in Human Term Placenta Reveals Unique Lipid Dynamics in Cytotrophoblast Cells.
Zhang LW, Zhu LL, Zhu XY, Fu SQ, Liu XM
Frontiers in pharmacology 2024;15:1337057
Frontiers in pharmacology 2024;15:1337057
Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice.
Zhang Z, Yang Q, Jin M, Wang J, Chai Y, Zhang L, Jiang Z, Yu Q
The international journal of biochemistry & cell biology 2024 Jul;172:106585
The international journal of biochemistry & cell biology 2024 Jul;172:106585
Hepatotoxicity induced in rats by chronic exposure to F-53B, an emerging replacement of perfluorooctane sulfonate (PFOS).
Li X, Zhang Q, Wang A, Shan S, Wang X, Wang Y, Wan J, Ning P, Hong C, Tian H, Zhao Y
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123544
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123544
Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment.
Surendran A, Jamalkhah M, Poutou J, Birtch R, Lawson C, Dave J, Crupi MJF, Mayer J, Taylor V, Petryk J, de Souza CT, Moodie N, Billingsley JL, Austin B, Cormack N, Blamey N, Rezaei R, McCloskey CW, Fekete EEF, Birdi HK, Neault S, Jamieson TR, Wylie B, Tucker S, Azad T, Vanderhyden B, Tai LH, Bell JC, Ilkow CS
Frontiers in immunology 2023;14:1099459
Frontiers in immunology 2023;14:1099459
Key enzyme in charge of ketone reabsorption of renal tubular SMCT1 may be a new target in diabetic kidney disease.
Guo Z, Zhong F, Hou M, Xie J, Zhang AZ, Li X, Li Y, Chang B, Yang J
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023 Nov 30;38(12):2754-2766
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023 Nov 30;38(12):2754-2766
Dynamic cellular changes in acute kidney injury caused by different ischemia time.
Shan D, Wang YY, Chang Y, Cui H, Tao M, Sheng Y, Kang H, Jia P, Song J
iScience 2023 May 19;26(5):106646
iScience 2023 May 19;26(5):106646
Letter to the editor: Adipose lipolysis is important for ethanol to induce fatty liver in the NIAAA murine model of chronic and binge ethanol feeding.
Luo W, Wang Y, Li Y, Zhang T
Hepatology (Baltimore, Md.) 2023 May 1;77(5):E88-E89
Hepatology (Baltimore, Md.) 2023 May 1;77(5):E88-E89
Adipose lipolysis is important for ethanol to induce fatty liver in the National Institute on Alcohol Abuse and Alcoholism murine model of chronic and binge ethanol feeding.
Mathur M, Yeh YT, Arya RK, Jiang L, Pornour M, Chen W, Ma Y, Gao B, He L, Ying Z, Xue B, Shi H, Choi Y, Yu L
Hepatology (Baltimore, Md.) 2023 May 1;77(5):1688-1701
Hepatology (Baltimore, Md.) 2023 May 1;77(5):1688-1701
FATP2 regulates non-small cell lung cancer by mediating lipid metabolism through ACSL1.
Chen Y, Zhao Y, Deng Y, Yang Y, Xu L, Fu J
Tissue & cell 2023 Jun;82:102105
Tissue & cell 2023 Jun;82:102105
Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease.
Ran LS, Wu YZ, Gan YW, Wang HL, Wu LJ, Zheng CM, Ming Y, Xiong R, Li YL, Lei SH, Wang X, Lao XQ, Zhang HM, Wang L, Chen C, Zhao CY
Journal of natural medicines 2023 Jan;77(1):73-86
Journal of natural medicines 2023 Jan;77(1):73-86
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate.
Chen Y, Yang S, Liu L, Yang X, Duan Y, Zhang S, Han J
European journal of pharmacology 2023 Jan 5;938:175428
European journal of pharmacology 2023 Jan 5;938:175428
Icariin Alleviates Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome by Improving Liver Fatty Acid Oxidation and Inhibiting Lipid Accumulation.
Hai Y, Zuo L, Wang M, Zhang R, Wang M, Ren L, Yang C, Wang J
Molecules (Basel, Switzerland) 2023 Jan 5;28(2)
Molecules (Basel, Switzerland) 2023 Jan 5;28(2)
Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice.
Guo R, Chen L, Zhu J, Li J, Ding Q, Chang K, Han Q, Li S
Food & function 2023 Feb 6;14(3):1573-1583
Food & function 2023 Feb 6;14(3):1573-1583
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway.
Shang K, Ma N, Che J, Li H, Hu J, Sun H, Cao B
BMC cancer 2023 Apr 11;23(1):335
BMC cancer 2023 Apr 11;23(1):335
Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol.
Guo R, Zhu J, Chen L, Li J, Ding Q, Han Q, Zheng W, Li S
Frontiers in nutrition 2022;9:1026740
Frontiers in nutrition 2022;9:1026740
Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice.
Hallows KR, Li H, Saitta B, Sepehr S, Huang P, Pham J, Wang J, Mancino V, Chung EJ, Pinkosky SL, Pastor-Soler NM
Frontiers in molecular biosciences 2022;9:1001941
Frontiers in molecular biosciences 2022;9:1001941
DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic Steatosis.
Luo L, Liu Y, Nizigiyimana P, Ye M, Xiao Y, Guo Q, Su T, Luo X, Huang Y, Zhou H
Cellular and molecular gastroenterology and hepatology 2022;14(6):1213-1233
Cellular and molecular gastroenterology and hepatology 2022;14(6):1213-1233
Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes.
Chu H, Zhao Q, Liu J, Yang K, Wang Y, Liu J, Zhang K, Zhao B, He H, Zheng Y, Zhong S, Liang Z, Zhang L, Zhang Y
Analytical chemistry 2022 Jan 18;94(2):758-767
Analytical chemistry 2022 Jan 18;94(2):758-767
Ameliorative Effect of Ethanolic Echinacea purpurea against Hyperthyroidism-Induced Oxidative Stress via AMRK and PPAR Signal Pathway Using Transcriptomics and Network Pharmacology Analysis.
Zhu Y, Zhang J, Wang C, Zheng T, Di S, Wang Y, Fei W, Liang W, Wang L
International journal of molecular sciences 2022 Dec 22;24(1)
International journal of molecular sciences 2022 Dec 22;24(1)
Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis.
Kim JL, Mestre B, Malitsky S, Itkin M, Kupervaser M, Futerman AH
The Journal of biological chemistry 2022 Apr;298(4):101735
The Journal of biological chemistry 2022 Apr;298(4):101735
B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36.
Zhang H, Li Y, Zhang C, Huang K, Zhao J, Le S, Jiang L, Liu H, Yang P, Xiao X, Yu J, Wu J, Ye P, Xia J
Cell death & disease 2022 Apr 18;13(4):359
Cell death & disease 2022 Apr 18;13(4):359
Sperm acquire epididymis-derived proteins through epididymosomes.
Barrachina F, Battistone MA, Castillo J, Mallofré C, Jodar M, Breton S, Oliva R
Human reproduction (Oxford, England) 2022 Apr 1;37(4):651-668
Human reproduction (Oxford, England) 2022 Apr 1;37(4):651-668
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Lei SS, Zhang NY, Zhou FC, He X, Wang HY, Li LZ, Zheng X, Dong YJ, Luo R, Li B, Jin HY, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
Lu J, Zhang Y, Sun M, Ding C, Zhang L, Kong Y, Cai M, Miccoli P, Ma C, Yue X
Frontiers in oncology 2021;11:737127
Frontiers in oncology 2021;11:737127
Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity.
Hua H, Zhang Y, Zhao F, Chen K, Wu T, Liu Q, Huang S, Zhang A, Jia Z
iScience 2021 Feb 19;24(2):102077
iScience 2021 Feb 19;24(2):102077
MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.
Wang X, Ma Y, Yang LY, Zhao D
Frontiers in cell and developmental biology 2020;8:596329
Frontiers in cell and developmental biology 2020;8:596329
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677
Frontiers in pharmacology 2019;10:1677
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
Orphan nuclear receptor NR4A1 suppresses hyperhomocysteinemia-induced hepatic steatosis in vitro and in vivo.
Liang H, Xie X, Song X, Huang M, Su T, Chang X, Liang B, Huang D
FEBS letters 2019 May;593(10):1061-1071
FEBS letters 2019 May;593(10):1061-1071
Rapid affinity purification of intracellular organelles using a twin strep tag.
Xiong J, He J, Xie WP, Hinojosa E, Ambati CSR, Putluri N, Kim HE, Zhu MX, Du G
Journal of cell science 2019 Dec 13;132(24)
Journal of cell science 2019 Dec 13;132(24)
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L
Archives of toxicology 2018 Jan;92(1):469-485
Archives of toxicology 2018 Jan;92(1):469-485
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2017 Aug 21;7(1):8976
Scientific reports 2017 Aug 21;7(1):8976
Real-Time Tracking of BODIPY-C12 Long-Chain Fatty Acid in Human Term Placenta Reveals Unique Lipid Dynamics in Cytotrophoblast Cells.
Kolahi K, Louey S, Varlamov O, Thornburg K
PloS one 2016;11(4):e0153522
PloS one 2016;11(4):e0153522
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 14048-1-AP(SLC27A2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SLC27A2 antibody 14048-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14048-1-AP(SLC27A2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14048-1-AP(SLC27A2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue