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- References [2119]
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- Product number
- 19677-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19677-1-AP, RRID:AB_10733244
- Product name
- Caspase 3/p17/p19 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Caspase 3/p17/p19 antibody (Cat. #19677-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glutamine Protects against Mouse Abdominal Aortic Aneurysm through Modulating VSMC Apoptosis and M1 Macrophage Activation.
Cancer Differentiation Inducer Chlorogenic Acid Suppresses PD-L1 Expression and Boosts Antitumor Immunity of PD-1 Antibody.
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
XYA-2: a marine-derived compound targeting apoptosis and multiple signaling pathways in pancreatic cancer.
Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.
Investigation of crucial genes and mitochondrial function impairment in diabetic cardiomyopathy.
Pongamol Prevents Neurotoxicity via the Activation of MAPKs/Nrf2 Signaling Pathway in H(2)O(2)-Induced Neuronal PC12 Cells and Prolongs the Lifespan of Caenorhabditis elegans.
HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA.
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
CACNA1B protects naked mole-rat hippocampal neuron from apoptosis via altering the subcellular localization of Nrf2 after (60)Co irradiation.
Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells.
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
Selective Organ-Targeting Hafnium Oxide Nanoparticles with Multienzyme-Mimetic Activities Attenuate Radiation-Induced Tissue Damage.
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Heme oxygenase 1 (HO1) regulates autophagy and apoptosis via the PI3K/AKT/mTOR signaling pathway of yak Sertoli cells.
Metal-Organic Framework-Mediated Synergistic Hypoxia-Activated Chemo-Immunotherapy Induced by High Intensity Focused Ultrasound for Enhanced Cancer Theranostics.
The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury.
Porphyromonas gingivalis suppresses oral squamous cell carcinoma progression by inhibiting MUC1 expression and remodeling the tumor microenvironment.
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
D-alanine suppressed osteoclastogenesis derived from bone marrow macrophages and downregulated ERK/p38 signalling pathways.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Knocking-down long non-coding RNA LINC01094 prohibits chondrocyte apoptosis via regulating microRNA-577/metal-regulatory transcription factor 1 axis.
The haemagglutinin-neuraminidase protein of velogenic Newcastle disease virus enhances viral infection through NF-κB-mediated programmed cell death.
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21.
Identification of immunogenic cell death-related damage-related molecular patterns (DAMPs) to predict outcomes in patients with head and neck squamous cell carcinoma.
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Indole-3-carboxaldehyde alleviates acetaminophen-induced liver injury via inhibition of oxidative stress and apoptosis.
SOD1-high fibroblasts derived exosomal miR-3960 promotes cisplatin resistance in triple-negative breast cancer by suppressing BRSK2-mediated phosphorylation of PIMREG.
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Abelmoschus manihot (L.) medik. seeds alleviate rheumatoid arthritis by modulating JAK2/STAT3 signaling pathway.
A unique circ_0067716/EIF4A3 double-negative feedback loop impacts malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene.
Cytotoxic withanolides from the stems and leaves of Physalis ixocarpa.
Overcoming the Blood-Brain Tumor Barrier with Docetaxel-Loaded Mesoporous Silica Nanoparticles for Treatment of Temozolomide-Resistant Glioblastoma.
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
The down-regulation of STC2 mRNA may serve as a biomarker for death from mechanical asphyxia.
Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy.
Notoginsenoside R1 attenuates bupivacaine induced neurotoxicity by activating Jak1/Stat3/Mcl1 pathway.
14-3-3-η interacts with BCL-2 to protect human endothelial progenitor cells from ox-LDL-triggered damage.
Hypothermic machine perfusion reduces donation after circulatory death liver ischemia-reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway.
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Potential Effects of Orally Ingesting Polyethylene Terephthalate Microplastics on the Mouse Heart.
C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells.
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer.
Enzymatically Bioactive Nucleus Pulposus Matrix Hydrogel Microspheres for Exogenous Stem Cells Therapy and Endogenous Repair Strategy to Achieve Disc Regeneration.
Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy.
LncTCONS_00058568 is involved in the pathophysiologic processes mediated by P2X7R in the lower thoracic spinal cord after acute kidney injury.
The therapeutic effect of anti-CD19 antibody on DHEA-induced PCOS mice.
Long non-coding RNA LINC01554 overexpression suppresses viability, migration, and invasion of liver cancer cells through regulating miR-148b-3p/EIF4E3.
A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection.
Electrospun nanofibrous mats loaded with gemcitabine and cisplatin suppress bladder tumor growth by improving the tumor immune microenvironment.
Exploring the hypoglycemic mechanism of chlorogenic acids from Pyrrosia petiolosa (Christ) Ching on type 2 diabetes mellitus based on network pharmacology and transcriptomics strategy.
Evaluation on the Potential for Hepatotoxic Components from Herba Epimedii to Induce Apoptosis in HepG2 Cells and the Analysis of the Influence of Metabolism in Liver Microsomes.
Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway.
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Pro-tumorigenic activity of PYCR1 in gastric cancer through regulating the PI3K/AKT signaling.
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
Effects of Dityrosine on Lactic Acid Metabolism in Mice Gastrocnemius Muscle During Endurance Exercise via the Oxidative Stress-Induced Mitochondria Damage.
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.
ATP5me alleviates high glucose-induced myocardial cell injury.
Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Inhibition of ROS/caspase-3/GSDME-mediated pyroptosis alleviates high glucose-induced injury in AML-12 cells.
GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis.
Celastrol enhances the viability of random-pattern skin flaps by regulating autophagy through the AMPK-mTOR-TFEB axis.
Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis.
Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury.
Cisplatin-activated and hemoglobin-mediated injectable hydrogel system for antitumor chemodynamic and chemotherapy.
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
The mechanism of curcumin to protect mouse ovaries from oxidative damage by regulating AMPK/mTOR mediated autophagy.
JinChan YiShen TongLuo Formula ameliorate mitochondrial dysfunction and apoptosis in diabetic nephropathy through the HIF-1α-PINK1-Parkin pathway.
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC.
Bradykinin protects nucleus pulposus cells from tert-butyl hydroperoxide-induced damage and delays intervertebral disc degeneration.
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway.
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress.
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.
Melatonin Exerts an Anti-Panoptoic Role in Spinal Cord Ischemia-Reperfusion Injured Rats.
Oridonin suppresses the growth of glioblastoma cells via inhibiting Hippo/YAP axis.
Mycobacterium tuberculosis PE_PGRS45 (Rv2615c) Promotes Recombinant Mycobacteria Intracellular Survival via Regulation of Innate Immunity, and Inhibition of Cell Apoptosis.
Selenomethionine protects the liver from dietary deoxynivalenol exposure via Nrf2/PPARγ-GPX4-ferroptosis pathway in mice.
Vitamin C enhances the sensitivity of osteosarcoma to arsenic trioxide via inhibiting aerobic glycolysis.
CircNEK6 promotes the progression of pancreatic ductal adenocarcinoma through targeting miR-503/CCND1 axis.
Diminazene aceturate-induced cytotoxicity is associated with the deregulation of cell cycle signaling and downregulation of oncogenes Furin, c-MYC, and FOXM1 in human cervical carcinoma Hela cells.
IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway.
N-n-butyl haloperidol iodide mediates cardioprotection via regulating AMPK/FoxO1 signalling.
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
In vitro anticancer effect of azithromycin targeting hypoxic lung cancer cells via the inhibition of mitophagy.
pH-driven preparation of pea protein isolate-curcumin nanoparticles effectively enhances antitumor activity.
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Methylglyoxal accumulation contributes to accelerated brain aging in spontaneously hypertensive rats.
hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia-reperfusion injury through the KEAP1/Nrf2/HO-1 signaling.
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Polyphyllin II (PPII) Enhances the Sensitivity of Multidrug-resistant A549/DDP Cells to Cisplatin by Modulating Mitochondrial Energy Metabolism.
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
METTL1 mediated tRNA m(7)G modification promotes leukaemogenesis of AML via tRNA regulated translational control.
Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis.
Loganin protects against myocardial ischemia-reperfusion injury by modulating oxidative stress and cellular apoptosis via activation of JAK2/STAT3 signaling.
E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis.
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.
Chemoproteomics Reveals Glaucocalyxin A Induces Mitochondria-Dependent Apoptosis of Leukemia Cells via Covalently Binding to VDAC1.
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines.
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells.
Axonal injury mediated by neuronal p75NTR/TRAF6/JNK pathway contributes to cognitive impairment after repetitive mTBI.
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation.
Resveratrol-laden mesoporous silica nanoparticles regulate the autophagy and apoptosis via ROS-mediated p38-MAPK/HIF-1a /p53 signaling in hypertrophic scar fibroblasts.
ADAR1 Inhibits Macrophage Apoptosis and Alleviates Sepsis-induced Liver Injury Through miR-122/BCL2A1 Signaling.
Valproic acid regulates the miR-155/Jarid2 axis by affecting miR-155 promoter methylation in glioma.
Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury.
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
Cold atmospheric plasma stabilizes mismatch repair for effective, uniform treatment of diverse colorectal cancer cell types.
Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells.
Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression.
Orthosiphon aristatus (Blume) Miq. Extracts attenuate Alzheimer-like pathology through anti-inflammatory, anti-oxidative, and β-amyloid inhibitory activities.
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf-κb pathway.
miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2.
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Apoptosis and pyroptosis in the nasal mucosa of Syrian hamster during SARS-CoV-2 infection and reinfection.
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Bacillus subtilis alleviates excessive apoptosis of intestinal epithelial cells in intrauterine growth restriction suckling piglets via the members of Bcl-2 and caspase families.
Seliciclib alleviates ulcerative colitis by inhibiting ferroptosis and improving intestinal inflammation.
Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.
Leonurus japonicus Houtt. modulates neuronal apoptosis in intracerebral hemorrhage: Insights from network pharmacology and molecular docking.
HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation.
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis.
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1.
A coumarin-furoxan hybrid as novel nitric oxide donor induced cell apoptosis and ferroptosis in NSCLC by promoting S-nitrosylation of STAT3 and negative regulation of JAK2-STAT3 pathway.
PGC-1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons.
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis.
Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3.
Regulatory mechanism of perinatal nonylphenol exposure on cardiac mitochondrial autophagy and the PINK1/Parkin signaling pathway in male offspring rats.
Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells.
NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16.
Sodium sulfite triggered hepatic apoptosis, necroptosis, and pyroptosis by inducing mitochondrial damage in mice and AML-12 cells.
LINC00942 Alleviates NaAsO(2)-induced Apoptosis by Promoting GSH Synthesis Through Targeting miR-214-5p.
Dynamic role of CUL4B in radiation-induced intestinal injury-regeneration.
Exploring the effective compounds and potential mechanisms of Shengxian Decoction against coronary heart disease by UPLC-Q-TOF/MS and network pharmacology analysis.
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Targeting IDH1-Mutated Oligodendroglioma with Acid Ceramidase Inhibitors.
Induction of IFIT1/IFIT3 and inhibition of Bcl-2 orchestrate the treatment of myeloma and leukemia via pyroptosis.
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats.
Diphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects.
Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
Discovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation.
B-Myb deficiency boosts bortezomib-induced immunogenic cell death in colorectal cancer.
Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling.
Tumor Supplying Artery Injection of Liposome@Sunitinib Could Effectively Inhibit the Progression of Kidney Tumor.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
zDHHC3-mediated S-palmitoylation of SLC9A2 regulates apoptosis in kidney clear cell carcinoma.
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Hepatocellular SETDB1 Regulates Hepatic Ischemia-Reperfusion Injury through Targeting Lysine Methylation of ASK1 Signal.
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression.
MiR-125b-5p/STAT3 Axis Regulates Drug Resistance in Osteosarcoma Cells by Acting on ABC Transporters.
A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways.
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage.
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
Melatonin Ameliorates Ovarian Hyperstimulation Syndrome (OHSS) through SESN2 Regulated Antiapoptosis.
Autophagy Inhibition Contributes to Apoptosis of PLK4 Downregulation-induced Dormant Cells in Colorectal Cancer.
Notoginsenoside R1 attenuates brain injury in rats with traumatic brain injury: Possible mediation of apoptosis via ERK1/2 signaling pathway.
Effect of matrine in MAC-T cells and their transcriptome analysis: A basic study.
WTAP affects intracranial aneurysm progression by regulating m6A methylation modification.
Bacterial lipoprotein plays an important role in the macrophage autophagy and apoptosis induced by Salmonella typhimurium and Staphylococcus aureus.
HK2 contributes to the proliferation, migration, and invasion of diffuse large B-cell lymphoma cells by enhancing the ERK1/2 signaling pathway.
Solanine Represses Gastric Cancer Growth by Mediating Autophagy Through AAMDC/MYC/ATF4/Sesn2 Signaling Pathway.
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease.
Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice.
Electroacupuncture alleviates ciliary muscle cell apoptosis in lens-induced myopic guinea pigs through inhibiting the mitochondrial signaling pathway.
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Artesunate, as an Hsp90 inhibitor, inhibits the proliferation of Burkitt's lymphoma cells by inhibiting AKT and ERK.
Uncovering the active constituents and mechanisms of Rujin Jiedu powder for ameliorating LPS-induced acute lung injury using network pharmacology and experimental investigations.
Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway.
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.
Ablation of NLRP3 inflammasome attenuates muscle atrophy via inhibiting pyroptosis, proteolysis and apoptosis following denervation.
LTe2 induces cell apoptosis in multiple myeloma by suppressing AKT phosphorylation at Thr308 and Ser473.
Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study.
Missing link between tissue specific expressing pattern of ERβ and the clinical manifestations in LGBLEL.
Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy.
Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation.
α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Pan-cancer integrated bioinformatic analysis of RNA polymerase subunits reveal RNA Pol I member CD3EAP regulates cell growth by modulating autophagy.
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Degradation of histone deacetylase 6 alleviates ROS-mediated apoptosis in renal ischemia-reperfusion injury.
Exploring the molecular mechanisms of the involvement of GZMB-Caspase-3-GSDME pathway in the progression of rheumatoid arthritis.
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling.
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway.
Oryza sativa L. Indica Seed Coat Ameliorated Concanavalin A-Induced Acute Hepatitis in Mice via MDM2/p53 and PKCα/MAPK1 Signaling Pathways.
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Downregulation of lncRNA NEAT1 interacts with miR-374b-5p/PGAP1 axis to aggravate the development of osteoarthritis.
Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease.
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
In Silico Identification and Validation of Pyroptosis-Related Genes in Chlamydia Respiratory Infection.
LncRNA AOC4P impacts the differentiation of macrophages and T-lymphocyte by regulating the NF-κB pathways of KGN cells: Potential pathogenesis of polycystic ovary syndrome.
Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice.
The PRMT5 inhibitor C9 mitigates hypoxia-induced carboplatin resistance in lung cancer by inducing autophagy.
Tenofovir disoproxil fumarate mediates neuronal injury by inducing neurotoxicity.
Electroacupuncture inhibits hippocampal neuronal apoptosis and improves cognitive dysfunction in mice with vascular dementia via the JNK signaling pathway.
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.
Effects of prenatal acetaminophen exposure at different stages, doses and courses on articular cartilage of offspring mice.
Kartogenin potentially protects temporomandibular joints from collagenase-induced osteoarthritis via core binding factor β and runt-related transcription factor 1 binding - A rat model study.
Isoflurane-induced reduction in neurogenesis derived from the tertiary dentate matrix.
Programmed Death Ligand-1-Overexpressing Donor Exosomes Mediate Donor-Specific Immunosuppression by Delivering Co-Inhibitory Signals to Donor-Specific T Cells.
MiR-132-3p activation aggravates renal ischemia-reperfusion injury by targeting Sirt1/PGC1alpha axis.
TNFAIP3 interacting protein 2 relieves lipopolysaccharide (LPS)-induced inflammatory injury in endometritis by inhibiting NF-kappaB activation.
Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM leukemia cells.
Combined Epimedii Folium and Ligustri Lucidi Fructus with dexamethasone alleviate the proliferation of airway smooth muscle cells by regulating apoptosis/autophagy.
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of proliferation and apoptosis of smooth muscle cells in vitro and in vivo.
Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly(β-amino ester)s.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
PABPN1 promotes clear cell renal cell carcinoma progression by suppressing the alternative polyadenylation of SGPL1 and CREG1.
Insulin-induced gene 2 protects against hepatic ischemia-reperfusion injury via metabolic remodeling.
Melatonin-Mediated Suppression of mtROS-JNK-FOXO1 Pathway Alleviates Hypoxia-Induced Apoptosis in Porcine Granulosa Cells.
Neuronal RBM5 modulates cell signaling responses to traumatic and hypoxic-ischemic injury in a sex-dependent manner.
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Dynamic changes of oligodendrogenesis in neonatal rats with hypoxic-ischemic white matter injury.
METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.
Peptide Characterization of Bovine Myocardium Hydrolysates and Its Ameliorative Effects on Doxorubicin-Induced Myocardial Injury in H9c2 Cells and in Mice.
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
Dapagliflozin suppress endoplasmic reticulum stress mediated apoptosis of chondrocytes by activating Sirt1.
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Chronic exposure to low-dose deltamethrin can lead to colon tissue injury through PRDX1 inactivation-induced mitochondrial oxidative stress injury and gut microbial dysbiosis.
Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Effect of miR-182-5p on apoptosis in myocardial infarction.
Protective effect and mechanism of procyanidin B2 against hypoxic injury of cardiomyocytes.
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
The Extract of Pinellia Ternata-Induced Apoptosis of Leukemia Cells by Regulating the Expression of Bax, Bcl-2 and Caspase-3 Protein Expression in Mice.
Pseudolaric acid B induces apoptosis associated with the mitochondrial and PI3K/AKT/mTOR pathways in triple‑negative breast cancer.
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
Ginkgolide K delays the progression of osteoarthritis by regulating YAP to promote the formation of cartilage extracellular matrix.
Tethering ATG16L1 or LC3 induces targeted autophagic degradation of protein aggregates and mitochondria.
Escherichia coli infection mediates pyroptosis via activating p53-p21 pathway-regulated apoptosis and cell cycle arrest in bovine mammary epithelial cells.
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
The eNOS-induced leonurine's new role in improving the survival of random skin flap.
A Dihydroartemisinin-Loaded Nanoreactor Motivates Anti-Cancer Immunotherapy by Synergy-Induced Ferroptosis to Activate Cgas/STING for Reprogramming of Macrophage.
Targeting Esophageal Squamous Cell Carcinoma by Combining Copper Ionophore Disulfiram and JMJD3/UTX Inhibitor GSK J4.
ADORA2A promotes proliferation and inhibits apoptosis through PI3K/AKT pathway activation in colorectal carcinoma.
SOX4 as a potential therapeutic target for pathological cardiac hypertrophy.
MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer.
Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation.
HDAC1-Mediated lncRNA Stimulatory Factor of Follicular Development to Inhibit the Apoptosis of Granulosa Cells and Regulate Sexual Maturity through miR-202-3p-COX1 Axis.
Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway.
DJ1 Ameliorates AD-like Pathology in the Hippocampus of APP/PS1 Mice.
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
Syndecan-1 shedding destroys epithelial adherens junctions through STAT3 after renal ischemia/reperfusion injury.
Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway.
Mechanism underlying the effect of Pulsatilla decoction in hepatocellular carcinoma treatment: a network pharmacology and in vitro analysis.
LIMK1 m(6)A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.
Effect of arsenic and copper in kidney of mice: Crosstalk between Nrf2/ Keap1 pathway in apoptosis and pyroptosis.
Novel soybean polypeptide dglycin alleviates atherosclerosis in apolipoprotein E-deficient mice.
FGF21 protects against doxorubicin-induced cardiotoxicity by inhibiting connexin 43 ubiquitination.
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Inhibition of endogenous hydrogen sulfide production suppresses the growth of nasopharyngeal carcinoma cells.
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.
MicroRNA152-3p Protects Against Ischemia/Reperfusion-Induced Bbb Destruction Possibly Targeting the MAP3K2/JNK/c-Jun Pathway.
IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis.
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Environmental microcystin exposure triggers the poor prognosis of prostate cancer: Evidence from case-control, animal, and in vitro studies.
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
p53 Activates the Lipoxygenase Activity of ALOX15B via Inhibiting SLC7A11 to Induce Ferroptosis in Bladder Cancer Cells.
Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis.
Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus.
Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma.
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD(+)/SIRT3 pathway.
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway.
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
USP11 exacerbates neuronal apoptosis after traumatic brain injury via PKM2-mediated PI3K/AKT signaling pathway.
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
UDP-glucuronate metabolism controls RIPK1-driven liver damage in nonalcoholic steatohepatitis.
Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization.
Qingyihuaji Formula promotes apoptosis and autophagy through inhibition of MAPK/ERK and PI3K/Akt/mTOR signaling pathway on pancreatic cancer in vivo and in vitro.
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21-5p/SOCS6 pathway.
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells.
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors.
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR-199b-5p and regulating STRN expression.
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
The combination of gemcitabine and ginsenoside Rh2 enhances the immune function of dendritic cells against pancreatic cancer via the CARD9-BCL10-MALT1 / NF-κB pathway.
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.
Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease.
SDNOR, a Novel Antioxidative lncRNA, Is Essential for Maintaining the Normal State and Function of Porcine Follicular Granulosa Cells.
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway.
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
An integrated approach of network pharmacology, molecular docking, and experimental verification uncovers kaempferol as the effective modulator of HSD17B1 for treatment of endometrial cancer.
Exposure to bisphenol A alternatives bisphenol AF and fluorene-9-bisphenol induces gonadal injuries in male zebrafish.
AAZ2 induces mitochondrial-dependent apoptosis by targeting PDK1 in gastric cancer.
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Aidi injection enhances the anti-tumor impact of doxorubicin in H22 tumor-containing mice.
Integrating metabolomics and network pharmacology to investigate Panax japonicus prevents kidney injury in HFD/STZ-induced diabetic mice.
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Ursolic acid nanoparticles for glioblastoma therapy.
1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B.
Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma.
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.
GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.
Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis.
Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells.
MicroRNA-324-3p inhibits osteosarcoma progression by suppressing PGAM1-mediated aerobic glycolysis.
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Potential Mechanisms of Metformin-Induced Apoptosis in HeLa Cells.
Codelivery of TRAIL and Mitomycin C via Liposomes Shows Improved Antitumor Effect on TRAIL-Resistant Tumors.
Alr Gene in Brucella suis S2: Its Role in Lipopolysaccharide Biosynthesis and Bacterial Virulence in RAW264.7.
The Natural Alkaloid (-)-N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex.
Effect of Lactobacillus delbrueckii subsp. lactis on vaginal radiotherapy for gynecological cancer.
DHCR24 reverses Alzheimer's disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xFAD mice.
[Cordycepin, a metabolite of Cordyceps militaris, inhibits xenograft tumor growth of tongue squamous cell carcinoma in nude mice].
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
A multi-bioresponsive self-assembled nano drug delivery system based on hyaluronic acid and geraniol against liver cancer.
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Blunting ROS/TRPML1 pathway protects AFB1-induced porcine intestinal epithelial cells apoptosis by restoring impaired autophagic flux.
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Open hepatic artery flow with portal vein clamping protects against bile duct injury compared to pringles maneuver.
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Pseudolaric acid B triggers cell apoptosis by activating AMPK/JNK/DRP1/mitochondrial fission pathway in hepatocellular carcinoma.
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
A mitochondria-targeting ROS-activated nanoprodrug for self-augmented antitumor oxidation therapy.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Silicate ions as soluble form of bioactive ceramics alleviate aortic aneurysm and dissection.
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice.
TLR4 Overexpression Aggravates Bacterial Lipopolysaccharide-Induced Apoptosis via Excessive Autophagy and NF-κB/MAPK Signaling in Transgenic Mammal Models.
Foot-and-Mouth Disease Virus Induces Porcine Gasdermin E-Mediated Pyroptosis through the Protease Activity of 3C(pro).
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Inhibition of FEN1 promotes DNA damage and enhances chemotherapeutic response in prostate cancer cells.
Hypothermic oxygenated perfusion attenuates DCD liver ischemia-reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum stress.
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma.
Carnosic Acid Attenuates AβOs-Induced Apoptosis and Synaptic Impairment via Regulating NMDAR2B and Its Downstream Cascades in SH-SY5Y Cells.
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
TGF-β1 regulates the lncRNA transcriptome of ovarian granulosa cells in a transcription activity-dependent manner.
TNFα-induced IDH1 hyperacetylation reprograms redox homeostasis and promotes the chemotherapeutic sensitivity.
Replication of standard bovine viral diarrhea strain OregonC24Va induces endoplasmic reticulum stress-mediated apoptosis of bovine trophoblast cells.
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Alternate-day fasting for the protection of cognitive impairment in c57BL/6J mice following whole-brain radiotherapy.
CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway.
Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.
Mechanism of action of Daqinjiao decoction in treating cerebral small vessel disease explored using network pharmacology and molecular docking technology.
Double-modified oncolytic adenovirus armed with a recombinant interferon-like gene enhanced abscopal effects against malignant glioma.
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury.
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate.
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds.
5-Hydroxytryptophan inhibits β-casein biosynthesis and promotes goat mammary epithelial cell apoptosis through the JAK2/STAT5a axis and the HTR7.
Lipopolysaccharide promotes apoptosis and oxidative injury of porcine small intestinal epithelial cells by down-regulating the expression of glutamine transporter ASCT2.
Honokiol reduces cadmium-induced oxidative injury and endosomal/lysosomal vacuolation via protecting mitochondrial function in quail (Coturnix japonica) liver tissues.
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Endosulfan induced kidney cell injury by modulating ACE2 through up-regulating miR-429 in HK-2 cells.
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
METTL3 Regulates Osteoclast Biological Behaviors via iNOS/NO-Mediated Mitochondrial Dysfunction in Inflammatory Conditions.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Intravenous Transplantation of an Ischemic-specific Peptide-TPP-mitochondrial Compound Alleviates Myocardial Ischemic Reperfusion Injury.
Aluminum exposure induces nephrotoxicity via fibrosis and apoptosis through the TGF-β1/Smads pathway in vivo and in vitro.
Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer's disease rat model.
Interleukin-32γ promotes macrophage-mediated chemoresistance by inducing CSF1-dependent M2 macrophage polarization in multiple myeloma.
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
SIRT7 silencing by miR-152-3p confers cell apoptosis and renal functional impairment induced by renal ischaemia/reperfusion injury.
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Curcumin alleviates ketamine-induced oxidative stress and apoptosis via Nrf2 signaling pathway in rats' cerebral cortex and hippocampus.
Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma.
Berberine promotes the viability of random skin flaps via the PI3K/Akt/eNOS signaling pathway.
DNMT1-mediated lncRNA IFFD controls the follicular development via targeting GLI1 by sponging miR-370.
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
A plant nonenveloped double-stranded RNA virus activates and co-opts BNIP3-mediated mitophagy to promote persistent infection in its insect vector.
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons.
Decreased expression and DNA hypermethylation of syncytin-1 in human villus tissues with unexplained recurrent spontaneous abortion.
Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats.
Spleen Toxicity of Organophosphorus Flame Retardant TDCPP in Mice and the Related Mechanisms.
The protective effect of the mitochondrial-derived peptide MOTS-c on LPS-induced septic cardiomyopathy.
Combined use of dasatinib and quercetin alleviates overtraining-induced deficits in learning and memory through eliminating senescent cells and reducing apoptotic cells in rat hippocampus.
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Salidroside Alleviates Diabetic Cognitive Dysfunction Via B3galt2/F3/Contactin Signaling Pathway in Mice.
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice.
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: Novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells.
MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells.
YM155 inhibits neuroblastoma growth through degradation of MYCN: A new role as a USP7 inhibitor.
TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin‒proteasome-mediated degradation of PRKCD.
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells.
Uqcr11 alleviates oxidative stress and apoptosis after traumatic brain injury.
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis.
Cold Stress Induces Apoptosis in Silver Pomfret via DUSP-JNK Pathway.
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Identification of a Difluorinated Alkoxy Sulfonyl Chloride as a Novel Antitumor Agent for Hepatocellular Carcinoma through Activating Fumarate Hydratase Activity.
Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.
Cynanchum komarovii extract for the treatment of rheumatoid arthritis by acting on synovial cells in vitro and in vivo.
hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Mesenchymal stem cell exosomes inhibit nucleus pulposus cell apoptosis via the miR-125b-5p/TRAF6/NF-κB pathway axis.
PD-L1 and AKT Overexpressing Adipose-Derived Mesenchymal Stem Cells Enhance Myocardial Protection by Upregulating CD25(+) T Cells in Acute Myocardial Infarction Rat Model.
Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression.
Cryptocaryone induces apoptosis in human hepatocellular carcinoma cells by inhibiting aerobic glycolysis through Akt and c-Src signaling pathways.
Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis.
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer.
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Mouth breathing induces condylar remodelling and chondrocyte apoptosis via both the extrinsic and mitochondrial pathways in male adolescent rats.
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.
Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS-mediated mitochondrial pathway.
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Role of Autophagy and Apoptosis in Aluminum Exposure-Induced Liver Injury in Rats.
Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy.
N-Acetylserotonin Protects Rat Nucleus Pulposus Cells Against Oxidative Stress Injury by Activating the PI3K/AKT Signaling Pathway.
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
SIRT6 deficiency in endothelial cells exacerbates oxidative stress by enhancing HIF1α accumulation and H3K9 acetylation at the Ero1α promoter.
Multi-Catcher Polymers Regulate the Nucleolin Cluster on the Cell Surface for Cancer Therapy.
The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.
Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Trimetazidine Affects Mitochondrial Calcium Uniporter Expression to Restore Ischemic Heart Function via Reactive Oxygen Species/NFκB Pathway Inhibition.
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro.
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Decreased autophagic activity of detrusor cells is involved in the inflammatory response of interstitial cystitis/bladder pain syndrome.
IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway.
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.
Structure-based discovery of novel α-aminoketone derivatives as dual p53-MDM2/MDMX inhibitors for the treatment of cancer.
Inflammation Control and Tumor Growth Inhibition of Ovarian Cancer by Targeting Adhesion Molecules of E-Selectin.
Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy.
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex.
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Antioxidant, Immunostimulatory, and Anticancer Properties of Hydrolyzed Wheat Bran Mediated through Macrophages Stimulation.
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Sulforaphane suppresses paraquat-induced oxidative damage in bovine in vitro-matured oocytes through Nrf2 transduction pathway.
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Effect of Two Different Drug-Resistant Staphylococcus aureus Strains on the Physiological Properties of MAC-T Cells and Their Transcriptome Analysis.
6-Shogaol Inhibits Oxidative Stress-Induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 Axis.
Effects of limonin treatment on the survival of random skin flaps in mice.
Calvatia Lilacina Extracts Exert Anti-Breast-Cancer Bioactivity through the Apoptosis Induction Dependent on Mitochondrial Reactive Oxygen Species and Caspase Activation.
Lycium barbarum polysaccharide attenuates Pseudomonas-aeruginosa pyocyanin-induced cellular injury in mice airway epithelial cells.
MiR-7015-3p Targets Nuclear Factor-Kappa-B-Inhibitor Alpha to Aggravate Hypoxia/Reoxygenation Injury in Cardiomyocytes Through the NF-κB Pathway.
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
Artesunate Suppresses the Growth of Lung Cancer Cells by Downregulating the AKT/Survivin Signaling Pathway.
Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction.
Protective Effect of Phloretin against Hydrogen Peroxide-Induced Oxidative Damage by Enhancing Autophagic Flux in DF-1 Cells.
Keratin 8 Is an Inflammation-Induced and Prognosis-Related Marker for Pancreatic Adenocarcinoma.
DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status.
Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21.
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Brevilin A Inhibits VEGF-Induced Angiogenesis through ROS-Dependent Mitochondrial Dysfunction.
Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy.
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
CORM-3 Attenuates Oxidative Stress-Induced Bone Loss via the Nrf2/HO-1 Pathway.
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway.
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis.
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell.
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer.
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
CIRBP-OGFR axis safeguards against cardiomyocyte apoptosis and cardiotoxicity induced by chemotherapy.
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca(2+)-FOXO1 pathway.
Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics.
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs.
Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin.
Zinc Oxide Particles Can Cause Ovarian Toxicity by Oxidative Stress in Female Mice Model.
Microglial infiltration mediates cognitive dysfunction in rat models of hypothalamic obesity via a hypothalamic-hippocampal circuit involving the lateral hypothalamic area.
Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Magnesium Lithospermate B Protects Against Cisplatin-Induced Acute Kidney Injury via Alleviating Mitochondrial Dysfunction.
Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction.
Expression and potential role of FOSB in glioma.
The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells.
Over-expression of miR-193a-3p regulates the apoptosis of colorectal cancer cells by targeting PAK3.
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Licoricidin combats gastric cancer by targeting the ICMT/Ras pathway in vitro and in vivo.
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Therapeutic effect and mechanism of combination therapy with ursolic acid and insulin on diabetic nephropathy in a type I diabetic rat model.
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis.
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H(2)O(2)-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation.
Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia.
Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling.
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Comprehensive analysis of hypoxia-related genes for prognosis value, immune status, and therapy in osteosarcoma patients.
Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis.
Sanguisorba officinalis L. suppresses non-small cell lung cancer via downregulating the PI3K/AKT/mTOR signaling pathway based on network pharmacology and experimental investigation.
Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-A(Thr288)-geminin dual signaling pathways.
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Depletion of PARP10 inhibits the growth and metastatic potential of oral squamous cell carcinoma.
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model.
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
A miR-137-XIAP axis contributes to the sensitivity of TRAIL-induced cell death in glioblastoma.
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
A nanobody-based molecular toolkit for ubiquitin-proteasome system explores the main role of survivin subcellular localization.
A mitochondria-targeted nano-platform for pancreatic cancer therapy.
Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation.
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis.
TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice.
Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma.
Ferulic acid ameliorates acetaminophen-induced acute liver injury by promoting AMPK-mediated protective autophagy.
MiR-325-3p Alleviates Acute Pancreatitis via Targeting RIPK3.
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Expression levels of caspase-3 and gasdermin E and their involvement in the occurrence and prognosis of lung cancer.
Acacetin antagonized lipotoxicity in pancreatic β-cells via ameliorating oxidative stress and endoplasmic reticulum stress.
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Protective Effect of Shenfu Injection on Vascular Endothelial Damage in a Porcine Model of Hemorrhagic Shock.
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Improvement of anticancer effect of berberine by salt formation modifications.
THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours.
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
SIRT1 modifies DNA methylation linked to synaptic deficits induced by Pb in vitro and in vivo.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Small extracellular vesicles of hypoxic endothelial cells regulate the therapeutic potential of adipose-derived mesenchymal stem cells via miR-486-5p/PTEN in a limb ischemia model.
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma.
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.
Oleuropein attenuates testicular ischemia-reperfusion by inhibiting apoptosis and inflammation.
Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.
Mechanism of Thymus Rejuvenation in Elderly Macaques.
Anodal transcranial direct current stimulation alleviates cognitive impairment in an APP/PS1 model of Alzheimer's disease in the preclinical stage.
Mechanical stretch aggravates vascular smooth muscle cell apoptosis and vascular remodeling by downregulating EZH2.
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Haizao Yuhu decoctions including three species of glycyrrhiza protected against propylthiouracil-induced goiter with hypothyroidism in rats via the AMPK/mTOR pathway.
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma.
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Geniposide attenuates spermatogenic dysfunction via inhibiting endoplasmic reticulum stress in male mice.
New insights into the interaction between duodenal toxicity and microbiota disorder under copper exposure in chicken: Involving in endoplasmic reticulum stress and mitochondrial toxicity.
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Naringenin induces endoplasmic reticulum stress-mediated cell apoptosis and autophagy in human oral squamous cell carcinoma cells.
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
AGR2-induced cholesterol synthesis drives lovastatin resistance that is overcome by combination therapy with allicin.
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis.
Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells.
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Human Umbilical Cord-Derived Mesenchymal Stem Cells Repair SU5416-Injured Emphysema by Inhibiting Apoptosis via Rescuing VEGF-VEGFR2-AKT Pathway in Rats.
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury.
Pt(IV) Prodrug as a Potential Antitumor Agent with APE1 Inhibitory Activity.
Mupirocin blocks imiquimod-induced psoriasis-like skin lesion by inhibiting epidermal isoleucyl-tRNA synthetase.
SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.
Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells.
Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization.
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
CD93 promotes acute myeloid leukemia development and is a potential therapeutic target.
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
GRP94 Inhabits the Immortalized Porcine Hepatic Stellate Cells Apoptosis under Endoplasmic Reticulum Stress through Modulating the Expression of IGF-1 and Ubiquitin.
HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Traditional Chinese medicine CFF-1 exerts a potent anti-tumor immunity to hinder tumor growth and metastasis in prostate cancer through EGFR/JAK1/STAT3 pathway to inhibit PD-1/PD-L1 checkpoint signaling.
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Impact and potential mechanism of effects of chronic moderate alcohol consumption on cardiac function in aldehyde dehydrogenase 2 gene heterozygous mice.
Selenium protects against cadmium-induced cardiac injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling.
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer.
Gasdermin E is required for induction of pyroptosis and severe disease during enterovirus 71 infection.
The application of CRISPR/Cas9 system in cervical carcinogenesis.
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
PM(2.5) induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Single-cell profiling-guided combination therapy of c-Fos and histone deacetylase inhibitors in diffuse large B-cell lymphoma.
Ubiquitin-specific protease 35 (USP35) mediates cisplatin-induced apoptosis by stabilizing BIRC3 in non-small cell lung cancer.
Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy.
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.
Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors.
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating T lymphocytes.
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells.
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Sevoflurane induced neurotoxicity in neonatal mice links to a GSK3β/Drp1-dependent mitochondrial fission and apoptosis.
Catalpol alleviates myocardial ischemia reperfusion injury by activating the Nrf2/HO-1 signaling pathway.
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification.
Design, synthesis and biological evaluation of marine phidianidine-inspired derivatives against oxidized ldl-induced endothelial injury by activating Nrf2 anti-oxidation pathway.
Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways.
Blocking protease-activated receptor 4 alleviates liver injury induced by brain death.
HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
Engineering Lipusu with lysophosphatidylcholine for improved tumor cellular uptake and anticancer efficacy.
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancerthrough inhibiting GPX4 and enhancing ROS.
Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H(+)] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.
Inhibition of STAT3(Y705) phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Oxidative stress activates Ryr2-Ca(2+) and apoptosis to promote PM(2.5)-induced heart injury of hyperlipidemia mice.
Microencapsulated islet transplantation alleviates podocyte injury in diabetic nephropathy via inhibiting Notch-1 signaling.
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
LncRNA small nucleolar RNA host gene 16 reduces sepsis-induced myocardial damage by regulating miR-421/suppressor of cytokine signaling 5 axis.
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
microRNA-486-5p is implicated in the cisplatin-induced apoptosis and acute inflammation response of renal tubular epithelial cells by targeting HAT1.
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis.
Beneficial effects of genistein in suppression of proliferation, inhibition of metastasis, and induction of apoptosis in PC3 prostate cancer cells.
The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction.
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
METTL3 mediates osteoblast apoptosis by regulating endoplasmic reticulum stress during LPS-induced inflammation.
PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway.
Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.
The involvement of TRPM2 on the MPP(+)-induced oxidative neurotoxicity and apoptosis in hippocampal neurons from neonatal mice: protective role of resveratrol.
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Melatonin improves bisphenol A-induced cell apoptosis, oxidative stress and autophagy impairment via inhibition of the p38 MAPK signaling pathway in FLK-BLV cells.
MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13.
SERPINA1 is a hub gene associated with intervertebral disc degeneration grade and affects the nucleus pulposus cell phenotype through the ADIRF-AS1/miR-214-3p axis.
Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis.
Targeted metabolomics analysis of bile acids and cell biology studies reveal the critical role of glycodeoxycholic acid in buffalo follicular atresia.
TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy.
Baicalin Induced Apoptosis of Human Cholangiocarcinoma Cell through Activating AMPK/mTORC1/p70S6K Signaling Pathway.
A New Berberine Preparation Protects Pancreatic Islet Cells from Apoptosis Mediated by Inhibition of Phospholipase A(2)/p38 MAPK Pathway.
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Endurance exercise-mediated metabolic reshuffle attenuates high-caloric diet-induced non-alcoholic fatty liver disease.
sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death.
Sulforaphane Acts Through NFE2L2 to Prevent Hypoxia-Induced Apoptosis in Porcine Granulosa Cells via Activating Antioxidant Defenses and Mitophagy.
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells.
PM2.5 promotes NSCLC carcinogenesis through translationally and transcriptionally activating DLAT-mediated glycolysis reprograming.
Exposure to Bisphenol A Caused Hepatoxicity and Intestinal Flora Disorder in Rats.
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
P2X7R/NLRP3 signaling pathway-mediated pyroptosis and neuroinflammation contributed to cognitive impairment in a mouse model of migraine.
Melatonin Alleviates Hyperglycemia-Induced Cardiomyocyte Apoptosis via Regulation of Long Non-Coding RNA H19/miR-29c/MAPK Axis in Diabetic Cardiomyopathy.
Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN.
Diffractaic acid, a novel TrxR1 inhibitor, induces cytotoxicity, apoptosis, and antimigration in human breast cancer cells.
Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Chlorogenic acid suppresses mitochondrial apoptotic effectors Bax/Bak to counteract Nod-like receptor pyrin domain 3 (NLRP3) inflammasome in thiram exposed chondrocytes.
Circular RNA circUSP13 sponges miR-29c to promote differentiation and inhibit apoptosis of goat myoblasts by targeting IGF1.
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H(2) S pathway in diabetic mice.
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise.
Thyroid stimulating hormone aggravates diabetic retinopathy through the mitochondrial apoptotic pathway.
Molecular Mechanism of Aluminum-Induced Oxidative Damage and Apoptosis in Rat Cardiomyocytes.
Cytotoxic new caged-polyprenylated xanthonoids from Garcinia oligantha.
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines.
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
lncRNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5.
lncRNA-encoded pep-AP attenuates the pentose phosphate pathway and sensitizes colorectal cancer cells to Oxaliplatin.
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Involvement of caspase in patulin-induced hepatotoxicity in vitro and in vivo.
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma.
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice.
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
The Role of RAD6B and PEDF in Retinal Degeneration.
Neuroprotective Effects of Tetrahydroxystilbene Glucoside against Rotenone-Induced Toxicity in PC12 Cells.
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenvironment.
Estrogen receptor-α36 is involved in diallyl sulfide-induced inhibition of malignant growth of HepG2 and Huh7 hepatocellular carcinoma cells.
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
Cardiotoxicity of patulin was found in H9c2 cells.
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.
Anticancer effects of myricetin derivatives in non-small cell lung cancer in vitro and in vivo.
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury through the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression.
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Asparaginyl endopeptidase protects against podocyte injury in diabetic nephropathy through cleaving cofilin-1.
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders.
Knocking Down Peroxiredoxin 6 Aggravates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitophagy.
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation.
A metabolomic approach to study triptolide-induced ovarian damage in rats.
Caveolin-1 suppresses hippocampal neuron apoptosis via the regulation of HIF1α in hypoxia in naked mole-rats.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Enhancement of the cytotoxic effect of dihydroartemisinin in high-risk human papillomavirus-infected cells by aminolevulinic acid via the Bax/Bcl-2-caspase pathway.
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Bone-targeted nanoplatform enables efficient modulation of bone tumor microenvironment for prostate cancer bone metastasis treatment.
Alfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway.
Nickel nanoparticles exert cytotoxic effects on trophoblast HTR-8/SVneo cells possibly via Nrf2/MAPK/caspase 3 pathway.
Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats.
GRN-/- iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis.
Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Idebenone reduces sepsis-induced oxidative stress and apoptosis in hepatocytes via RAGE/p38 signaling.
Elsholtzia bodinieri Vaniot Ameliorated Acute Lung Injury by NQO1, BCL2 and PTGS2 In Silico and In Vitro Analyses.
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Multi-specific niflumic acid platinum(IV) complexes displaying potent antitumor activities by improving immunity and suppressing angiogenesis besides causing DNA damage.
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Synergistic Effects of the Combinational Use of Escitalopram Oxalate and 5-Fluorouracil on the Inhibition of Gastric Cancer SNU-1 Cells.
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death.
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts.
Totipotency of miR-184 in porcine granulosa cells.
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Thiram induces myocardial oxidative damage and apoptosis in broilers via interfering their cardiac metabolism.
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Protective role of selenium on MPP(+) and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells.
DDX3X alleviates doxorubicin-induced cardiotoxicity by regulating Wnt/β-catenin signaling pathway in an in vitro model.
MiR-383-5p promotes apoptosis of ovarian granulosa cells by targeting CIRP through the PI3K/AKT signaling pathway.
Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells.
Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
The miR-410-5p /ITGA6 axis participates in the pathogenesis of recurrent abortion by regulating the biological function of trophoblast.
GFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation.
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Notoginsenoside R1 alleviates spinal cord injury by inhibiting oxidative stress, neuronal apoptosis, and inflammation via activating the nuclear factor erythroid 2 related factor 2/heme oxygenase-1 signaling pathway.
Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy.
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Development of a series of flurbiprofen and zaltoprofen platinum(IV) complexes with anti-metastasis competence targeting COX-2, PD-L1 and DNA.
Chiral FA Conjugated CdTe/CdS Quantum Dots for Selective Cancer Ablation.
Investigation of the effects of high cervical spinal cord electrical stimulation on improving neurological dysfunction and its potential mechanism in rats with traumatic brain injury.
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI.
METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner.
Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy.
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Exosomal circ-CACNG2 promotes cardiomyocyte apoptosis in multiple myeloma via modulating miR-197-3p/caspase3 axis.
Investigation and experimental validation of curcumin-related mechanisms against hepatocellular carcinoma based on network pharmacology.
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Ginseng oligosaccharides protect neurons from glutamate-induced oxidative damage through the Nrf2/HO-1 signaling pathway.
12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis.
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.
GSK-126 Protects CA1 Neurons from H3K27me3-Mediated Apoptosis in Cerebral Ischemia.
LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Sevoflurane impairs m6A-mediated mRNA translation and leads to fine motor and cognitive deficits.
Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κ B and PI3K/AKT Signaling In Vitro and In Vivo.
BMAL1 regulates mitochondrial homeostasis in renal ischaemia-reperfusion injury by mediating the SIRT1/PGC-1α axis.
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer.
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
The interferon regulatory factor 6 promotes cisplatin sensitivity in colorectal cancer.
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels.
Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway.
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Dietary Tryptophan Supplementation Improves Antioxidant Status and Alleviates Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Pyroptosis in the Intestine of Piglets after Lipopolysaccharide Challenge.
Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia.
Berberine alleviates LPS-induced apoptosis, oxidation, and skewed lineages during mouse preimplantation development†.
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment.
Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.
Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells.
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
NaAsO(2) decreases GSH synthesis by inhibiting GCLC and induces apoptosis through Hela cell mitochondrial damage, mediating the activation of the NF-κB/miR-21 signaling pathway.
PARP1 Inhibitor Combined With Oxaliplatin Efficiently Suppresses Oxaliplatin Resistance in Gastric Cancer-Derived Organoids via Homologous Recombination and the Base Excision Repair Pathway.
Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Transcriptomic Data Analyses Reveal That Sow Fertility-Related lincRNA NORFA Is Essential for the Normal States and Functions of Granulosa Cells.
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Validated Impacts of N6-Methyladenosine Methylated mRNAs on Apoptosis and Angiogenesis in Myocardial Infarction Based on MeRIP-Seq Analysis.
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Differentiation Under Cisplatin-Induced ROS Exposure.
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Pilose Antler Peptide-3.2KD Ameliorates Adriamycin-Induced Myocardial Injury Through TGF-β/SMAD Signaling Pathway.
Quercetin Antagonizes Glucose Fluctuation Induced Renal Injury by Inhibiting Aerobic Glycolysis via HIF-1α/miR-210/ISCU/FeS Pathway.
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
EphA2 overexpression reduces H2O2-induced damage of lens epithelial cells.
Shen-fu injection alleviates acute renal injury by reducing cytokine levels and modulating apoptosis in a porcine hemorrhagic shock model.
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Erteng-Sanjie Capsule Enhances Chemosensitivity of 5-Fluorouracil in Tumor-Bearing Nude Mice with Gastric Cancer by Inhibiting Notch1/Hes1 Signaling Pathway.
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Huxie Huaji Ointment Induced Apoptosis of Liver Cancer Cells In Vivo and In Vitro by Activating the Mitochondrial Pathway.
Escin Sodium Improves the Prognosis of Acute Pancreatitis via Promoting Cell Apoptosis by Suppression of the ERK/STAT3 Signaling Pathway.
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Hypoxia-Induced Autophagy Enhances Cisplatin Resistance in Human Bladder Cancer Cells by Targeting Hypoxia-Inducible Factor-1α.
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
Sodium Houttuyfonate Ameliorates β-amyloid(1-42)-Induced Memory Impairment and Neuroinflammation through Inhibiting the NLRP3/GSDMD Pathway in Alzheimer's Disease.
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway.
Programmed NP Cell Death Induced by Mitochondrial ROS in a One-Strike Loading Disc Degeneration Organ Culture Model.
Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling.
TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.
Mechanism by Which Tong Xie Yao Fang Heals the Intestinal Mucosa of Rats with Ulcerative Colitis through the Hippo Pathway.
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways.
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
γ-Glutamylcysteine Alleviates Ischemic Stroke-Induced Neuronal Apoptosis by Inhibiting ROS-Mediated Endoplasmic Reticulum Stress.
TSH Combined with TSHR Aggravates Diabetic Peripheral Neuropathy by Promoting Oxidative Stress and Apoptosis in Schwann Cells.
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress.
Resistance of bone marrow mesenchymal stem cells in a stressed environment - Comparison with osteocyte cells.
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Integrating Network Pharmacology and Experimental Verification to Explore the Mechanism of Effect of Zuojin Pills in Pancreatic Cancer Treatment.
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma.
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
miR-21-5p inhibits inflammation injuries in LPS-treated H9c2 cells by regulating PDCD4.
LncRNA TMPO-AS1 serves as a sponge for miR-4731-5p modulating breast cancer progression through FOXM1.
Role of Cytokines Released During Pyroptosis in Non-Small Cell Lung Cancer.
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
SAA1 knockdown promotes the apoptosis of glioblastoma cells via downregulation of AKT signaling.
PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway.
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology.
Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells.
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Naringin Exerts Therapeutic Effects on Mice Colitis: A Study Based on Transcriptomics Combined With Functional Experiments.
Mechanisms Underlying the Effects of Lianhua Qingwen on Sepsis-Induced Acute Lung Injury: A Network Pharmacology Approach.
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Enterovirus 71 Induces INF2 Cleavage via Activated Caspase-2 in Infected RD Cells.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures.
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.
The lncRNA CASC2 Modulates Hepatocellular Carcinoma Cell Sensitivity and Resistance to TRAIL Through Apoptotic and Non-Apoptotic Signaling.
Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway.
An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis.
A Novel Mechanism of the c-Myc/NEAT1 Axis Mediating Colorectal Cancer Cell Response to Photodynamic Therapy Treatment.
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
The Long Non-coding RNA TMPO-AS1 Promotes Bladder Cancer Growth and Progression via OTUB1-Induced E2F1 Deubiquitination.
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Downregulating Long Non-coding RNAs CTBP1-AS2 Inhibits Colorectal Cancer Development by Modulating the miR-93-5p/TGF-β/SMAD2/3 Pathway.
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
SPAG6-silencing enhances decitabine-induced apoptosis and demethylation of PTEN in SKM-1 cells and in a xenograft mouse model.
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Knockdown of PYCR1 suppressed the malignant phenotype of human hepatocellular carcinoma cells via inhibiting the AKT pathway activation.
Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease.
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma.
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer.
Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation.
TRAIL produced by SAM-1-activated CD4(+) and CD8(+) subgroup T cells induces apoptosis in human tumor cells through upregulation of death receptors.
Hydroxychloroquine alleviates the neurotoxicity induced by anti-ribosomal P antibodies.
Rubioncolin C, a natural naphthohydroquinone dimer isolated from Rubia yunnanensis, inhibits the proliferation and metastasis by inducing ROS-mediated apoptotic and autophagic cell death in triple-negative breast cancer cells.
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Esculetin inhibits endometrial cancer proliferation and promotes apoptosis via hnRNPA1 to downregulate BCLXL and XIAP.
Prolonged exposure to the herbicide atrazine suppresses immune cell functions by inducing spleen cell apoptosis in rats.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Curcuma oil ameliorates benign prostatic hyperplasia through suppression of the nuclear factor-kappa B signaling pathway in rats.
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
Sequential drug delivery by injectable macroporous hydrogels for combined photodynamic-chemotherapy.
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway.
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
Imidacloprid increases intestinal permeability by disrupting tight junctions.
Comparison of biological and transcriptomic effects of conventional cigarette and electronic cigarette smoke exposure at toxicological dose in BEAS-2B cells.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling.
WNK3 Promotes Neuronal Survival after Traumatic Brain Injury in Rats.
Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer.
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
Anti-glioblastoma effects of nanomicelle-curcumin plus erlotinib.
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Activation of HSP70 impedes tert-butyl hydroperoxide (t-BHP)-induced apoptosis and senescence of human nucleus pulposus stem cells via inhibiting the JNK/c-Jun pathway.
Near-infrared emission Cu, N-doped carbon dots for human umbilical vein endothelial cell labeling and their biocompatibility in vitro.
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy.
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway.
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis.
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
[Heat stress induces neuronal apoptosis by up-regulating endoplasmic reticulum stress pathway].
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Chlorogenic acid inhibits proliferation in human hepatoma cells by suppressing noncanonical NF-κB signaling pathway and triggering mitochondrial apoptosis.
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer.
Cordyceps acid alleviates lung cancer in nude mice.
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia-reperfusion injury.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Sperm Parameters, ASAs and Apoptosis After Processing by the Double Tube and Swim up Methods.
circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression.
PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer.
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1α pathway.
Adenine nucleotide translocase 2, a putative target protein for 2-carba cyclic phosphatidic acid in microglial cells.
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of Alzheimer's disease.
Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy.
Role of the BDNF/TrkB/CREB signaling pathway in the cytotoxicity of bisphenol S in SK-N-SH cells.
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1.
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells†.
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
Hypoxia induces chemoresistance of esophageal cancer cells to cisplatin through regulating the lncRNA-EMS/miR-758-3p/WTAP axis.
Pre-emptive pharmacological inhibition of fatty acid-binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism.
Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.
Transforming Growth Factor Beta 1 and p44/42 Expression in Cardinal Ligament Tissues of Patients with Pelvic Organ Prolapse.
DNA methylation mediated RSPO2 to promote follicular development in mammals.
TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression.
Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity.
Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.
CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K‑Akt‑mTOR pathway inhibition.
Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis.
Dynamin 3 overexpression suppresses the proliferation, migration and invasion of cervical cancer cells.
2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop.
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process.
Prognostic SLC family genes promote cell proliferation, migration, and invasion in hepatocellular carcinoma.
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Pseudoginsengenin DQ exerts antitumour activity against hypopharyngeal cancer cells by targeting the HIF-1α-GLUT1 pathway.
Timolol induces necroptosis, apoptosis and senescence concentration-dependently in rabbit Limbal stem cells in vitro.
Type 2 Alveolar Epithelial Cells Differentiated from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Mouse Pulmonary Fibrosis Through β-Catenin-Regulated Cell Apoptosis.
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway.
Metabolomic analysis of spontaneous neutrophil apoptosis reveals the potential involvement of glutathione depletion.
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Melatonin Alleviates Hypoxia-Induced Apoptosis of Granulosa Cells by Reducing ROS and Activating MTNR1B-PKA-Caspase8/9 Pathway.
Cytoprotective Effects of Taurine on Heat-Induced Bovine Mammary Epithelial Cells In Vitro.
Ameliorative effect of recombinant human lactoferrin on the premature ovarian failure in rats after cyclophosphamide treatments.
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration.
LncRNA SNHG16 contributes to tumor progression via the miR-302b-3p/SLC2A4 axis in pancreatic adenocarcinoma.
Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study.
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
ALKBH5-mediated m(6)A demethylation of FOXM1 mRNA promotes progression of uveal melanoma.
Deficiency of NEAT1 prevented MPP(+)-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters.
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation.
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Curcumin Ameliorates Copper-Induced Neurotoxicity Through Inhibiting Oxidative Stress and Mitochondrial Apoptosis in SH-SY5Y Cells.
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
PRSS55 plays an important role in the structural differentiation and energy metabolism of sperm and is required for male fertility in mice.
Increased expression of IFN-γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Yak milk-derived exosomal microRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment.
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway.
CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma.
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
AK003290 Protects Myocardial Cells Against Apoptosis and Promotes Cardiac Function Recovery Via miR-539-3p/ErbB4 Axis in Ischemic-Reperfusion Injury.
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
The endocytic pathway of Pt nanoclusters and their induced apoptosis of A549 and A549/Cis cells through c-Myc/p53 and Bcl-2/caspase-3 signaling pathways.
Corosolic acid reduces A549 and PC9 cell proliferation, invasion, and chemoresistance in NSCLC via inducing mitochondrial and liposomal oxidative stress.
The XBP1‒MARCH5‒MFN2 Axis Confers Endoplasmic Reticulum Stress Resistance by Coordinating Mitochondrial Fission and Mitophagy in Melanoma.
Sequential Epiphyseal Cartilage Changes of Femoral Heads in C57BL/6 Female Mice Treated with Excessive Glucocorticoids.
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension.
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Recombinant protein Schistosoma japonicum-derived molecule attenuates dextran sulfate sodium-induced colitis by inhibiting miRNA-217-5p to alleviate apoptosis.
TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension.
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Vitamin E regulates bovine granulosa cell apoptosis via NRF2-mediated defence mechanism by activating PI3K/AKT and ERK1/2 signalling pathways.
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway.
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.
Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.
Vitamin E and selenium supplementation synergistically alleviate the injury induced by hydrogen peroxide in bovine granulosa cells.
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation.
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
Autophagy Delays Apoptotic Cell Death Induced by Siniperca chuatsi Rhabdovirus in Epithelioma Papulosum Cyprinid Cells.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis.
Transcriptome Analysis Reveals the Potential Role of Long Noncoding RNAs in Regulating Fowl Adenovirus Serotype 4-Induced Apoptosis in Leghorn Male Hepatocellular Cells.
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation.
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Targeting hypoxia for sensitization of tumors to apoptosis enhancement through supramolecular biohybrid bacteria.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells.
NCX3 alleviates ethanol-induced apoptosis of SK-N-SH cells via the elimination of intracellular calcium ions.
Resveratrol-induced apoptosis is associated with regulating the miR-492/CD147 pathway in malignant melanoma cells.
Coaction of hepatic thioredoxin and glutathione systems in iron overload-induced oxidative stress.
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Exosomal miR-27 negatively regulates ROS production and promotes granulosa cells apoptosis by targeting SPRY2 in OHSS.
PBK promotes aggressive phenotypes of cervical cancer through ERK/c-Myc signaling pathway.
Morroniside protects OLN-93 cells against H(2)O(2)-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities.
Abnormal Glu/mGluR(2/3)/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Dracomolphin A-E, new lignans from Dracocephalum moldavica.
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.
Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase.
The Crosstalk between Autophagy and Apoptosis Is Necessary for Myogenic Differentiation.
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
A Bioinformatics Analysis Identifies the Telomerase Inhibitor MST-312 for Treating High-STMN1-Expressing Hepatocellular Carcinoma.
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Grape seed proanthocyanidins protect PC12 cells from hydrogen peroxide-induced damage via the PI3K/AKT signaling pathway.
Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis.
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Inhibiting Heat Shock Protein 90 Protects Nucleus Pulposus-Derived Stem/Progenitor Cells From Compression-Induced Necroptosis and Apoptosis.
Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression.
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α.
Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway.
Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors.
Metabolomic Analysis of the Ameliorative Effect of Enhanced Proline Metabolism on Hypoxia-Induced Injury in Cardiomyocytes.
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways.
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Neuroprotective Effect of the Inhibitor Salubrinal after Cardiac Arrest in a Rodent Model.
Experimental Study on the Effect of Aconite and Angelica sinensis on Myocardial Ischemia Rats with Yang Deficiency and Blood Stasis.
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats.
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Antitumor Effects of Curcumin and Glycyrrhetinic Acid-Modified Curcumin-Loaded Cationic Liposome by Intratumoral Administration.
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway.
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
miR193b Promotes Apoptosis of Gastric Cancer Cells via Directly Mediating the Akt Pathway.
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
The Protective Effect of Adiponectin-Transfected Endothelial Progenitor Cells on Cognitive Function in D-Galactose-Induced Aging Rats.
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity.
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Liquiritigenin-Loaded Submicron Emulsion Protects Against Doxorubicin-Induced Cardiotoxicity via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activity.
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib.
Chronic Unpredictable Mild Stress Accelerates the Growth of Bladder Cancer in a Xenograft Mouse Model.
Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery.
Deubiquitinase PSMD7 regulates cell fate and is associated with disease progression in breast cancer.
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
Long non-coding RNA KRT16P2/miR-1294/EGFR axis regulates laryngeal squamous cell carcinoma cell aggressiveness.
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
Baohuoside I via mTOR Apoptotic Signaling to Inhibit Glioma Cell Growth.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.
Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance.
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Morroniside Inhibits H(2)O(2)-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
miR-149-5p Regulates Goat Hair Follicle Stem Cell Proliferation and Apoptosis by Targeting the CMTM3/AR Axis During Superior-Quality Brush Hair Formation.
Role of Endoplasmic Reticulum Stress in Otitis Media.
PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4(+) and CD8(+) T Cells During BVDV Infection in vitro.
α-Cyperone Attenuates H(2)O(2)-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2.
Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling.
Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy.
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis.
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells.
Combination Therapy of Prostate Cancer by Oncolytic Adenovirus Harboring Interleukin 24 and Ionizing Radiation.
Caspase-3 inhibitor inhibits enterovirus D68 production.
Apigetrin ameliorates streptozotocin-induced pancreatic β-cell damages via attenuating endoplasmic reticulum stress.
Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma.
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
A novel antisense lncRNA NT5E promotes progression by modulating the expression of SYNCRIP and predicts a poor prognosis in pancreatic cancer.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Valproic acid overcomes sorafenib resistance by reducing the migration of Jagged2-mediated Notch1 signaling pathway in hepatocellular carcinoma cells.
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers.
Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele.
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
MiR-489 aggravates H2O2-induced apoptosis of cardiomyocytes via inhibiting IGF1.
Globular CTRP9 protects cardiomyocytes from palmitic acid-induced oxidative stress by enhancing autophagic flux.
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Protective effects of alfalfa saponins on oxidative stress-induced apoptotic cells.
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Sphingomyelin Synthase 2 Participate in the Regulation of Sperm Motility and Apoptosis.
Involvement of JNK/FOXO1 pathway in apoptosis induced by severe hypoxia in porcine granulosa cells.
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Proanthocyanidin B2 inhibits proliferation and induces apoptosis of osteosarcoma cells by suppressing the PI3K/AKT pathway.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Potential hazardous effects of printing room PM2.5 exposure include promotion of lung inflammation and subsequent injury.
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Inhibitory effect of Lycium barbarum polysaccharide on sperm damage during cryopreservation.
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.
Effect of Zhenxin Xingshui Yizhi Fang on Aβ(25-35) induced expression of related transporters in HBMEC cell model.
Activation of Sirtuin1 by lyceum barbarum polysaccharides in protection against diabetic cataract.
Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.
Cortistatin protects against inflammatory airway diseases through curbing CCL2 and antagonizing NF-κB signaling pathway.
Loss of RAD6B induces degeneration of the cochlea in mice.
NO66 overexpression rescues ethanol-induced cell apoptosis in human AC16 cardiomyocytes by suppressing PTEN and activating the PI3K/Akt signaling.
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice.
Hypoxia Protects Rat Bone Marrow Mesenchymal Stem Cells Against Compression-Induced Apoptosis in the Degenerative Disc Microenvironment Through Activation of the HIF-1α/YAP Signaling Pathway.
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats.
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
ITCH regulates oxidative stress induced by high glucose through thioredoxin interacting protein in cultured human lens epithelial cells.
Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells.
Ghrelin mitigates MPP(+)-induced cytotoxicity: Involvement of ERK1/2-mediated Nrf2/HO-1 and endoplasmic reticulum stress PERK signaling pathway.
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway.
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Functionalized graphene oxide against U251 glioma cells and its molecular mechanism.
Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2.
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.
Swine MicroRNAs ssc-miR-221-3p and ssc-miR-222 Restrict the Cross-Species Infection of Avian Influenza Virus.
Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway.
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
Hesperidin ameliorates hypobaric hypoxia-induced retinal impairment through activation of Nrf2/HO-1 pathway and inhibition of apoptosis.
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Edaravone attenuates myocyte apoptosis through the JAK2/STAT3 pathway in acute myocardial infarction.
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats.
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2.
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms.
Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice.
α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish.
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
SMAD4 activates Wnt signaling pathway to inhibit granulosa cell apoptosis.
Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke.
Gasdermine E-Dependent Mitochondrial Pyroptotic Pathway in Dermatomyositis: A Possible Mechanism of Perifascicular Atrophy.
Comprehensive identification of signaling pathways for idiopathic pulmonary arterial hypertension.
Camellia oil (Camellia oleifera Abel.) attenuates CCl(4)-induced liver fibrosis via suppressing hepatocyte apoptosis in mice.
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
LncRNA FAM66C inhibits pancreatic cancer progression by sponging miR-574-3p.
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway.
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
miR-7112-3p targets PERK to regulate the endoplasmic reticulum stress pathway and apoptosis induced by photodynamic therapy in colorectal cancer CX-1 cells.
Acrolein-induced apoptosis of smooth muscle cells through NEAT1-Bmal1/Clock pathway and a protection from asparagus extract.
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis.
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway.
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α.
Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway.
Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model.
Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis.
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis.
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
The roles of SHANK1 in the development of colon cancer.
2-Deoxy-D-glucose enhances the anti-cancer effects of idarubicin on idarubicin-resistant P388 leukemia cells.
ZX-29, a novel ALK inhibitor, induces apoptosis via ER stress in ALK rearrangement NSCLC cells and overcomes cell resistance caused by an ALK mutation.
Mkrn2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis.
Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells.
Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation.
An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury.
Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury.
Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Disruption of Midkine gene reduces traumatic brain injury through the modulation of neuroinflammation.
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression.
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis.
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Effect of S-Allyl -L-Cysteine on MCF-7 Cell Line 3-Mercaptopyruvate Sulfurtransferase/Sulfane Sulfur System, Viability and Apoptosis.
The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice.
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
PUMA-mediated epithelial cell apoptosis promotes Helicobacter pylori infection-mediated gastritis.
Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways.
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
FAIM-S functions as a negative regulator of NF-κB pathway and blocks cell cycle progression in NSCLC cells.
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
SMARCA2 is regulated by NORFA-miR-29c, a novel pathway that controls granulosa cell apoptosis and is related to female fertility.
Cryogen spray cooling mitigates inflammation and injury-induced CISD2 decline in rat spinal cord hemisection model.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR-200c-3p to upregulate ANLN.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner.
Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
A mitochondria-targeted anticancer nanoplatform with deep penetration for enhanced synergistic sonodynamic and starvation therapy.
Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARγ(1).
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway.
Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation.
Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2.
Inhibition of microRNA-327 ameliorates ischemia/reperfusion injury-induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain.
The Effects of Daxx Knockout on Pluripotency and Differentiation of Mouse Induced Pluripotent Stem Cells.
METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway.
The inhibitory effect and safety of GANT61 on HeLa cells in nude mice.
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis.
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
PTEN-induced kinase 1-induced dynamin-related protein 1 Ser637 phosphorylation reduces mitochondrial fission and protects against intestinal ischemia reperfusion injury.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene.
Resveratrol Attenuates Aflatoxin B(1)-Induced ROS Formation and Increase of m(6)A RNA Methylation.
VX-765 attenuates atherosclerosis in ApoE deficient mice by modulating VSMCs pyroptosis.
The FSH-HIF-1α-VEGF Pathway Is Critical for Ovulation and Oocyte Health but Not Necessary for Follicular Growth in Mice.
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation.
Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.
Saikosaponin A Inhibits Triple-Negative Breast Cancer Growth and Metastasis Through Downregulation of CXCR4.
SIX1 Activates STAT3 Signaling to Promote the Proliferation of Thyroid Carcinoma via EYA1.
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
Gefitinib-coated balloon inhibits the excessive hyperplasia of intima after vascular injuries through PI3K/AKT pathway.
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms.
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.
Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell.
RRM2 is a potential prognostic biomarker with functional significance in glioma.
Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway.
Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression.
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Treatment With 2-BFI Attenuated Spinal Cord Injury by Inhibiting Oxidative Stress and Neuronal Apoptosis via the Nrf2 Signaling Pathway.
Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway.
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.
Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress.
NCAPG Promotes The Proliferation Of Hepatocellular Carcinoma Through PI3K/AKT Signaling.
GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis.
Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells.
P-AKT2/SPK1 (P-SPK1) and P-MEK/P-ERK cell signaling pathways are involved in LPS-induced macrophage migration.
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies.
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Simultaneous Inhibition of EGFR and HER2 via Afatinib Augments the Radiosensitivity of Nasopharyngeal Carcinoma Cells.
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
The Radiosensitization of Sodium Glycididazole on Nasopharyngeal Carcinoma Cells via Enhancing DNA Damage and Promoting Apoptosis.
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer.
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice.
Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression.
Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration.
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
Prazosin inhibits the growth and mobility of osteosarcoma cells.
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells.
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Cypermethrin exposure reduces the ovarian reserve by causing mitochondrial dysfunction in granulosa cells.
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
DNA methylation and RASSF4 expression are involved in T-2 toxin-induced hepatotoxicity.
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Comparison of hypoxic effects induced by chemical and physical hypoxia on cardiomyocytes.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
The protective effect of Cordycepin on diabetic nephropathy through autophagy induction in vivo and in vitro.
Linc01105 acts as an oncogene in the development of neuroblastoma.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Rapamycin Protects Spiral Ganglion Neurons from Gentamicin-Induced Degeneration In Vitro.
CircINHA resists granulosa cell apoptosis by upregulating CTGF as a ceRNA of miR-10a-5p in pig ovarian follicles.
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
The protective effects of salvianolic acid A against hepatic ischemia-reperfusion injury via inhibiting expression of toll-like receptor 4 in rats.
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Overexpression of lncRNA WWTR1-AS1 associates with tumor aggressiveness and unfavorable survival in head-neck squamous cell carcinoma.
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling.
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer.
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma.
Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure.
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.
The oncogenic role of NKAP in the growth and invasion of colon cancer cells.
Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis.
Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice.
FoxD2-AS1 is a prognostic factor in glioma and promotes temozolomide resistance in a O(6)-methylguanine-DNA methyltransferase-dependent manner.
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Astragaloside IV attenuates myocardial ischemia/reperfusion injury in rats via inhibition of calcium-sensing receptor-mediated apoptotic signaling pathways.
Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway.
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.
Exogenous testosterone alleviates cardiac fibrosis and apoptosis via Gas6/Axl pathway in the senescent mice.
Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide.
Suppressing the Na(+)/H(+) exchanger 1: a new sight to treat depression.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Dkk1 exacerbates doxorubicin-induced cardiotoxicity by inhibiting the Wnt/β-catenin signaling pathway.
Synergistic effects of Pb and repeated heat pulse on developmental neurotoxicity in zebrafish.
Estrogen-related receptor-α mediates puromycin aminonucleoside-induced mesangial cell apoptosis and inflammatory injury.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
Organotypic slice culture based on in ovo electroporation for chicken embryonic central nervous system.
Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells.
Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Overexpression of Pyruvate Dehydrogenase E1α Subunit Inhibits Warburg Effect and Induces Cell Apoptosis Through Mitochondria-Mediated Pathway in Hepatocellular Carcinoma.
H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma.
Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy.
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.
Iron chelation effect of curcumin and baicalein on aplastic anemia mouse model with iron overload.
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
PKCδ contributes to oxidative stress-induced apoptosis in porcine ovarian granulosa cells via activating JNK.
Potent and specific MTH1 inhibitors targeting gastric cancer.
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Modulation of PTEN by hexarelin attenuates coronary artery ligation-induced heart failure in rats.
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
S-allyl-l-cysteine (SAC) protects hepatocytes from alcohol-induced apoptosis.
Synthesized glucocorticoid-induced leucine zipper peptide inhibits photoreceptor apoptosis and protects retinal function in light-induced retinal degeneration model.
Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
Activation of TRPC6 channels contributes to (+)-conocarpan-induced apoptotic cell death in HK-2 cells.
Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis.
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction.
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity.
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Downregulation of microRNA-196a attenuates ischemic brain injury in rats by directly targeting HMGA1.
Radioprotective effects of roxadustat (FG-4592) in haematopoietic system.
Nischarin attenuates apoptosis induced by oxidative stress in PC12 cells.
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
Estrogen receptor variant ER-α36 promotes tamoxifen agonist activity in glioblastoma cells.
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.
Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway.
A Novel Mutant of rLj-RGD3 (rLj-112) Suppressed the Proliferation and Metastasis of B16 Cells through the EGFR Signaling Pathway.
Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis.
A phenanthroline derivative enhances radiosensitivity of hepatocellular carcinoma cells by inducing mitochondria-dependent apoptosis.
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Evaluation of Iodine-125 Interstitial Brachytherapy Using Micro-Positron Emission Tomography/Computed Tomography with 18F-Fluorodeoxyglucose in Hepatocellular Carcinoma HepG2 Xenografts.
Role of ZIP8 in regulation of cisplatin sensitivity through Bcl-2.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
The protective role of IL-1Ra on intestinal ischemia reperfusion injury by anti-oxidative stress via Nrf2/HO-1 pathway in rat.
Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model.
Oxymatrine Inhibits Bocavirus MVC Replication, Reduces Viral Gene Expression and Decreases Apoptosis Induced by Viral Infection.
MiR-15b is a key regulator of proliferation and apoptosis of chondrocytes from patients with condylar hyperplasia by targeting IGF1, IGF1R and BCL2.
DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats.
Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids.
Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis.
Role of mitochondrial damage in Cr(VI)‑induced endoplasmic reticulum stress in L‑02 hepatocytes.
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway.
Long non-coding RNA TP73‑AS1 promotes colorectal cancer proliferation by acting as a ceRNA for miR‑103 to regulate PTEN expression.
κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway.
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damage.
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Restoration of p53 acetylation by HDAC inhibition permits the necrosis/apoptosis switch of pancreatic ainar cell during experimental pancreatitis in mice.
Effects of kojic acid on boar sperm quality and anti-bacterial activity during liquid preservation at 17 C.
miR-885-5p Negatively Regulates Warburg Effect by Silencing Hexokinase 2 in Liver Cancer.
The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5.
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation.
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages.
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis.
Soluble CXCL16 promotes TNF-α-induced apoptosis in DLBCL via the AMAD10-NF-κB regulatory feedback loop.
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
Sinoporphyrin sodium based sonodynamic therapy induces anti-tumor effects in hepatocellular carcinoma and activates p53/caspase 3 axis.
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.
Resveratrol induces apoptosis of benign prostatic hyperplasia epithelial cell line (BPH-1) through p38 MAPK-FOXO3a pathway.
VceC Mediated IRE1 Pathway and Inhibited CHOP-induced Apoptosis to Support Brucella Replication in Goat Trophoblast Cells.
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma.
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells.
Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals.
Protective effects of ethyl gallate on H(2)O(2)-induced mitochondrial dysfunction in PC12 cells.
Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro.
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Deficiency of TPPP2, a factor linked to oligoasthenozoospermia, causes subfertility in male mice.
Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem.
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling.
Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.
Knockdown MTMR14 promotes cell apoptosis and inhibits migration in liver cancer cells.
Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice.
Effects of agomelatine in rotenone-induced Parkinson's disease in rats.
Effects of 220 MHz Pulsed Modulated Radiofrequency Field on the Sperm Quality in Rats.
PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation.
Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model.
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
circEPSTI1 as a Prognostic Marker and Mediator of Triple-Negative Breast Cancer Progression.
Icariside II, a Phosphodiesterase-5 Inhibitor, Attenuates Beta-Amyloid-Induced Cognitive Deficits via BDNF/TrkB/CREB Signaling.
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1.
The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells.
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link.
Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway.
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma.
TMCO1 is essential for ovarian follicle development by regulating ER Ca(2+) store of granulosa cells.
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation.
Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity.
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Tumor-targeting core-shell structured nanoparticles for drug procedural controlled release and cancer sonodynamic combined therapy.
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo.
Knockdown of ribosomal protein S15A inhibits proliferation of breast cancer cells through induction of apoptosis in vitro.
Titanium dioxide nanoparticles induce mouse hippocampal neuron apoptosis via oxidative stress- and calcium imbalance-mediated endoplasmic reticulum stress.
Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway.
Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca(2+)Production.
β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors.
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Antitumor activities of novel glycyrrhetinic acid-modified curcumin-loaded cationic liposomes in vitro and in H22 tumor-bearing mice.
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.
Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.
Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury.
Lenalidomide improvement of cisplatin antitumor efficacy on triple-negative breast cancer cells in vitro.
Matrine reversed multidrug resistance of breast cancer MCF-7/ADR cells through PI3K/AKT signaling pathway.
Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling pathway.
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice.
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
The orphan nuclear receptor NR4A1 attenuates oxidative stress-induced β cells apoptosis via up-regulation of glutathione peroxidase 1.
Dysfunction of DNA damage-inducible transcript 4 in the decidua is relevant to the pathogenesis of preeclampsia.
Adenovirus-mediated overexpression of sST2 attenuates cardiac injury in the rat with severe acute pancreatitis.
The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma.
Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy.
Molecular targeting of glutaminase sensitizes ovarian cancer cells to chemotherapy.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Seminal plasma miR-192a: a biomarker predicting successful resolution of nonobstructive azoospermia following varicocele repair.
Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells.
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.
UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis.
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells.
Protective Effect of Selenoprotein X Against Oxidative Stress-Induced Cell Apoptosis in Human Hepatocyte (LO2) Cells via the p38 Pathway.
Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.
The inhibitory effects of soybean isoflavones on testicular cell apoptosis in mice with type 2 diabetes.
Tetrahydroxystilbene glucoside relieves the chronic inflammatory pain by inhibiting neuronal apoptosis, microglia activation, and GluN2B overexpression in anterior cingulate cortex.
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
PLK1 protects against sepsis-induced intestinal barrier dysfunction.
Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling.
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365.
Inhibition of REDD1 Sensitizes Bladder Urothelial Carcinoma to Paclitaxel by Inhibiting Autophagy.
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitis.
HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.
hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway.
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Effects of mdig on proliferation and apoptosis of lung cancer cells.
Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Canonical Transient Receptor Potential Channel 3 Contributes to Febrile Seizure Inducing Neuronal Cell Death and Neuroinflammation.
Therapeutic effects of the novel subtype-selective histone deacetylase inhibitor chidamide on myeloma-associated bone disease.
Activation of neuronal N-methyl-D-aspartate receptor plays a pivotal role in Japanese encephalitis virus-induced neuronal cell damage.
Memantine can improve chronic ethanol exposure-induced spatial memory impairment in male C57BL/6 mice by reducing hippocampal apoptosis.
Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells.
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
Endoplasmic Reticulum Stress Facilitates the Survival and Proliferation of Nucleus Pulposus Cells in TNF-α Stimulus by Activating Unfolded Protein Response.
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways.
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress.
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
The Targeted Antitumor Effects of C- PC/CMC-CD59sp Nanoparticles on HeLa Cells in Vitro and in Vivo.
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway.
Exogenous H2S Protects Against Diabetic Cardiomyopathy by Activating Autophagy via the AMPK/mTOR Pathway.
Sulforaphane-cysteine-induced apoptosis via phosphorylated ERK1/2-mediated maspin pathway in human non-small cell lung cancer cells.
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Therapy Effects of Wogonin on Ovarian Cancer Cells.
Relaxin Attenuates Contrast-Induced Human Proximal Tubular Epithelial Cell Apoptosis by Activation of the PI3K/Akt Signaling Pathway In Vitro.
MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS.
Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.
Reactive oxygen species-driven mitochondrial injury induces apoptosis by teroxirone in human non-small cell lung cancer cells.
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression.
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Neuroprotective effect of G(14)-humanin on global cerebral ischemia/reperfusion by activation of SOCS3 - STAT3 - MCL-1 signal transduction pathway in rats.
A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres.
Humanin analogue, S14G-humanin, has neuroprotective effects against oxygen glucose deprivation/reoxygenation by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathway.
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.
Studies on the cytotoxicity and anticancer performance of heterocyclic hypervalent organobismuth(III) compounds.
Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
Cysteine-rich buccal gland protein suppressed the proliferation, migration and invasion of hela cells through akt pathway.
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Inhibited effects of CAPE-pNO(2) on cervical carcinoma in vivo and in vitro and its detected metabolites.
Overexpression of T-box Transcription Factor 5 (TBX5) Inhibits Proliferation and Invasion in Non-Small Cell Lung Carcinoma Cells.
Losartan protects against cerebral ischemia/reperfusion-induced apoptosis through β-arrestin1-mediated phosphorylation of Akt.
Edaravone ameliorates compression-induced damage in rat nucleus pulposus cells.
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Geniposide protects pancreatic β cells from high glucose-mediated injury by activation of AMP-activated protein kinase.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells.
7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice.
12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis.
Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice.
Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice.
Exogenous H(2)S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway.
Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines.
Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery.
The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways.
Bone marrow mesenchymal stem cells repair cadmium-induced rat testis injury by inhibiting mitochondrial apoptosis.
DKK3 regulates cell proliferation, apoptosis and collagen synthesis in keloid fibroblasts via TGF-β1/Smad signaling pathway.
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Sesamol attenuates oxidative stress, apoptosis and inflammation in focal cerebral ischemia/reperfusion injury.
Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin.
Hypertonic saline infusion suppresses apoptosis of hippocampal cells in a rat model of cardiopulmonary resuscitation.
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Cortistatin Improves Cardiac Function After Acute Myocardial Infarction in Rats by Suppressing Myocardial Apoptosis and Endoplasmic Reticulum Stress.
Effects of visfatin on the apoptosis of intestinal mucosal cells in immunological stressed rats.
Carboxyfullerene nanoparticles alleviate acute hepatic injury in severe hemorrhagic shock.
Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells.
Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress, NF-κB inhibition and mitochondrial dysfunction.
Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression.
Inhibition of store-operated Ca(2+) entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate.
Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway.
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice.
Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis.
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Abnormal expression levels of BMP15/Smad1 are associated with granulosa cell apoptosis in patients with polycystic ovary syndrome.
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Regulation of macrophage migration in ischemic mouse hearts via an AKT2/NBA1/SPK1 pathway.
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Effect of Boron on Thymic Cytokine Expression, Hormone Secretion, Antioxidant Functions, Cell Proliferation, and Apoptosis Potential via the Extracellular Signal-Regulated Kinases 1 and 2 Signaling Pathway.
miR-19a protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis via PTEN/PI3K/p-Akt pathway.
Boron Affects Immune Function Through Modulation of Splenic T Lymphocyte Subsets, Cytokine Secretion, and Lymphocyte Proliferation and Apoptosis in Rats.
Treatment mechanism of matrine in combination with irinotecan for colon cancer.
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Establishment of an ideal time window model in hypothermic-targeted temperature management after traumatic brain injury in rats.
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
Long-term effects of repeated superovulation on the uterus and mammary gland in rhesus monkeys.
MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3.
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa.
Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Chronic Sleep Deprivation Exacerbates Learning-Memory Disability and Alzheimer's Disease-Like Pathologies in AβPP(swe)/PS1(ΔE9) Mice.
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin.
Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway.
OFD1, as a Ciliary Protein, Exhibits Neuroprotective Function in Photoreceptor Degeneration Models.
Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.
Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet.
SIRT2 Plays Significant Roles in Lipopolysaccharides-Induced Neuroinflammation and Brain Injury in Mice.
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway.
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis.
Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway.
Knockdown of Myosin 6 inhibits proliferation of oral squamous cell carcinoma cells.
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis.
Multifunctional Gold Nanoclusters-Based Nanosurface Energy Transfer Probe for Real-Time Monitoring of Cell Apoptosis and Self-Evaluating of Pro-Apoptotic Theranostics.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.
Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack.
β-Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-κB Signaling Pathway.
Phosphocreatine protects against LPS-induced human umbilical vein endothelial cell apoptosis by regulating mitochondrial oxidative phosphorylation.
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress.
Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia.
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma.
Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells.
Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells.
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.
Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.
Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice.
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Corilagin Attenuates Radiation-Induced Brain Injury in Mice.
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin.
Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy.
HspB8 mediates neuroprotection against OGD/R in N2A cells through the phosphoinositide 3-kinase/Akt pathway.
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice.
MiR-124 effect in neurons apoptosis in newborn rat with thyroid hypofunction.
Level of circulated microRNA-421 in gastric carcinoma and related mechanisms.
Effects of the total saponins from Dioscorea nipponica on immunoregulation in aplastic anemia mice.
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
A comparison of the biological effects of 125I seeds continuous low-dose-rate radiation and 60Co high-dose-rate gamma radiation on non-small cell lung cancer cells.
Decreased expression of RPS15A suppresses proliferation of lung cancer cells.
Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice.
Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.
Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus.
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Oxymatrine attenuated hypoxic-ischemic brain damage in neonatal rats via improving antioxidant enzyme activities and inhibiting cell death.
Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.
XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy.
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker.
An ESRG-interacting protein, COXII, is involved in pro-apoptosis of human embryonic stem cells.
Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells.
MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer.
MiR-17-5p up-regulates YES1 to modulate the cell cycle progression and apoptosis in ovarian cancer cell lines.
Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma.
The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats.
Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.
Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway.
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Potent effects of dioscin against liver fibrosis.
IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
Traumatic brain injury dysregulates microRNAs to modulate cell signaling in rat hippocampus.
Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice.
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
14-Thienyl methylene matrine (YYJ18), the derivative from matrine, induces apoptosis of human nasopharyngeal carcinoma cells by targeting MAPK and PI3K/Akt pathways in vitro.
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Gastrodin prevents steroid-induced osteonecrosis of the femoral head in rats by anti-apoptosis.
Inhibition of autophagy enhances the anticancer activity of silver nanoparticles.
Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons.
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Protective effects of dioscin against alcohol-induced liver injury.
Matrine-induced apoptosis of human nasopharyngeal carcinoma cells via in vitro vascular endothelial growth factor-A/extracellular signal-regulated kinase1/2 pathway inactivation.
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice.
Oxysophoridine protects against focal cerebral ischemic injury by inhibiting oxidative stress and apoptosis in mice.
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis.
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Total flavonoids from Rosa Laevigata Michx fruit attenuates hydrogen peroxide induced injury in human umbilical vein endothelial cells.
Wang J, Da X, Chen Y, Yuan A, Pu J
International journal of medical sciences 2024;21(8):1414-1427
International journal of medical sciences 2024;21(8):1414-1427
Cancer Differentiation Inducer Chlorogenic Acid Suppresses PD-L1 Expression and Boosts Antitumor Immunity of PD-1 Antibody.
Li R, Zhan Y, Ding X, Cui J, Han Y, Zhang J, Zhang J, Li W, Wang L, Jiang J
International journal of biological sciences 2024;20(1):61-77
International journal of biological sciences 2024;20(1):61-77
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Du J, Liu W, Song Y, Zhang Y, Dong C, Xiong S, Huang Z, Wang T, Ding J, He Q, Yu Z, Ma X
Burns & trauma 2024;12:tkad057
Burns & trauma 2024;12:tkad057
XYA-2: a marine-derived compound targeting apoptosis and multiple signaling pathways in pancreatic cancer.
Guan X, Li Y, Guan X, Fan L, Ying J
PeerJ 2024;12:e16805
PeerJ 2024;12:e16805
Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.
Ge Y, Xia T, Feng Z, Xi Y, Hu D, Hong Y, Tang B, Wu J, Chen J, Xiao H
Andrology 2024 Sep;12(6):1439-1448
Andrology 2024 Sep;12(6):1439-1448
Investigation of crucial genes and mitochondrial function impairment in diabetic cardiomyopathy.
Tuersuntuoheti M, Zhou L, Li J, Yang S, Zhou S, Gong H
Gene 2024 Sep 25;923:148563
Gene 2024 Sep 25;923:148563
Pongamol Prevents Neurotoxicity via the Activation of MAPKs/Nrf2 Signaling Pathway in H(2)O(2)-Induced Neuronal PC12 Cells and Prolongs the Lifespan of Caenorhabditis elegans.
Wu S, Miao J, Zhu S, Wu X, Shi J, Zhou J, Xing Y, Hu K, Ren J, Yang H
Molecular neurobiology 2024 Oct;61(10):8219-8233
Molecular neurobiology 2024 Oct;61(10):8219-8233
HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA.
Jin T, Wang Z, Fan F, Wei W, Zhou C, Zhang Z, Gao Y, Li W, Zhu L, Hao J
Neurochemical research 2024 Oct;49(10):2699-2724
Neurochemical research 2024 Oct;49(10):2699-2724
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Zeng H, Xu J, Wu R, Wang X, Jiang Y, Wang Q, Guo J, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
Yang Y, Du J, Gan J, Song X, Shu J, An C, Lu L, Wei H, Che J, Zhao X
Advanced healthcare materials 2024 Oct;13(26):e2401198
Advanced healthcare materials 2024 Oct;13(26):e2401198
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
Shen NX, Qu XC, Yu J, Fan CX, Min FL, Li LY, Zhang MR, Li BM, Wang J, He N, Liao WP, Shi YW, Li WB
Molecular neurobiology 2024 Nov;61(11):8518-8530
Molecular neurobiology 2024 Nov;61(11):8518-8530
CACNA1B protects naked mole-rat hippocampal neuron from apoptosis via altering the subcellular localization of Nrf2 after (60)Co irradiation.
Yang W, Chen C, Jiang X, Zhao Y, Wang J, Zhang Q, Zhang J, Feng Y, Cui S
Cell biology international 2024 May;48(5):695-711
Cell biology international 2024 May;48(5):695-711
Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells.
Shi Z, Yan J, Zhao M, Li S, She T, Qian X
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:658-667
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:658-667
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
Yao L, Cong R, Zhou X, Zhou X, Ji C, Wei X, Meng X, Song N
International journal of impotence research 2024 May;36(3):283-290
International journal of impotence research 2024 May;36(3):283-290
Selective Organ-Targeting Hafnium Oxide Nanoparticles with Multienzyme-Mimetic Activities Attenuate Radiation-Induced Tissue Damage.
Liu D, Cao F, Xu Z, Zhao C, Liu Z, Pang J, Liu ZX, Moghiseh M, Butler A, Liang S, Fan W, Yang J
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(19):e2308098
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(19):e2308098
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Lan Y, Tian F, Tang H, Pu P, He Q, Duan L
Molecular medicine reports 2024 May;29(5)
Molecular medicine reports 2024 May;29(5)
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
Chen J, Bai X, Zhang W, Yan Z, Liu Y, Zhou S, Wu X, He X, Yang A
Journal of cellular and molecular medicine 2024 May;28(9):e18328
Journal of cellular and molecular medicine 2024 May;28(9):e18328
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Tuersuntuoheti M, Peng F, Li J, Zhou L, Gao H, Gong H
Biochemical pharmacology 2024 May;223:116142
Biochemical pharmacology 2024 May;223:116142
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
Heme oxygenase 1 (HO1) regulates autophagy and apoptosis via the PI3K/AKT/mTOR signaling pathway of yak Sertoli cells.
Yan Q, Wang Q, Nan J, Chen T, Wang J, Zhang Y, Yuan L
Theriogenology 2024 May;220:96-107
Theriogenology 2024 May;220:96-107
Metal-Organic Framework-Mediated Synergistic Hypoxia-Activated Chemo-Immunotherapy Induced by High Intensity Focused Ultrasound for Enhanced Cancer Theranostics.
Sun T, Li J, Zhou Y, Zeng C, Luo C, Luo X, Li H
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(18):e2306338
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(18):e2306338
The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury.
Zhao Y, Li T, Jiang Z, Gai C, Yu S, Xin D, Li T, Liu D, Wang Z
Neural regeneration research 2024 May;19(5):1084-1094
Neural regeneration research 2024 May;19(5):1084-1094
Porphyromonas gingivalis suppresses oral squamous cell carcinoma progression by inhibiting MUC1 expression and remodeling the tumor microenvironment.
Lan Z, Zou KL, Cui H, Zhao YY, Yu GT
Molecular oncology 2024 May;18(5):1174-1188
Molecular oncology 2024 May;18(5):1174-1188
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
Li T, Hu X, Fan L, Yang Y, He K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
D-alanine suppressed osteoclastogenesis derived from bone marrow macrophages and downregulated ERK/p38 signalling pathways.
Chang X, Deng J, Zhou F, Geng Z, Li X, Wang S
Archives of oral biology 2024 May;161:105912
Archives of oral biology 2024 May;161:105912
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
Knocking-down long non-coding RNA LINC01094 prohibits chondrocyte apoptosis via regulating microRNA-577/metal-regulatory transcription factor 1 axis.
Huang F, Su Z, Yang J, Zhao X, Xu Y
Journal of orthopaedic surgery (Hong Kong) 2024 May-Aug;32(2):10225536241254588
Journal of orthopaedic surgery (Hong Kong) 2024 May-Aug;32(2):10225536241254588
The haemagglutinin-neuraminidase protein of velogenic Newcastle disease virus enhances viral infection through NF-κB-mediated programmed cell death.
Lu X, Zhan T, Zhou Q, Yang W, Liu K, Chen Y, Gao R, Hu J, Gu M, Hu S, Jiao XA, Wang X, Liu X, Liu X
Veterinary research 2024 May 7;55(1):58
Veterinary research 2024 May 7;55(1):58
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21.
Zhou X, Shen K, Cao S, Li P, Xiao J, Dong J, Cheng Q, Hu L, Xu Z, Yang L
Cancer cell international 2024 May 7;24(1):159
Cancer cell international 2024 May 7;24(1):159
Identification of immunogenic cell death-related damage-related molecular patterns (DAMPs) to predict outcomes in patients with head and neck squamous cell carcinoma.
Zhang J, Shi X, Wang M, Zhai R, Wang M, Gong Z, Ni Z, Xu T, Zhu W, Liu L
Journal of cancer research and clinical oncology 2024 May 7;150(5):240
Journal of cancer research and clinical oncology 2024 May 7;150(5):240
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Jiang S, Ma F, Lou J, Li J, Shang X, Li Y, Wu J, Xu S
European journal of pharmacology 2024 May 5;970:176455
European journal of pharmacology 2024 May 5;970:176455
Indole-3-carboxaldehyde alleviates acetaminophen-induced liver injury via inhibition of oxidative stress and apoptosis.
Liu X, Liu R, Wang Y
Biochemical and biophysical research communications 2024 May 28;710:149880
Biochemical and biophysical research communications 2024 May 28;710:149880
SOD1-high fibroblasts derived exosomal miR-3960 promotes cisplatin resistance in triple-negative breast cancer by suppressing BRSK2-mediated phosphorylation of PIMREG.
Li K, Lin H, Liu A, Qiu C, Rao Z, Wang Z, Chen S, She X, Zhu S, Li P, Liu L, Wu Q, Wang G, Xu F, Li S
Cancer letters 2024 May 28;590:216842
Cancer letters 2024 May 28;590:216842
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Liu J, Huang Y, Qian T, Chen J, Ding Y, Lai Z, Zhong X, Lai M, Zhang H, Wang Y, Wang H, Peng Y
Cell communication and signaling : CCS 2024 May 14;22(1):269
Cell communication and signaling : CCS 2024 May 14;22(1):269
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Wang B, Pan S, Nie C, Zou R, Liu J, Han X, Dong L, Zhang J, Yang X, Yu M, Fan B, Hong X, Yang W
Scientific reports 2024 May 14;14(1):10959
Scientific reports 2024 May 14;14(1):10959
Abelmoschus manihot (L.) medik. seeds alleviate rheumatoid arthritis by modulating JAK2/STAT3 signaling pathway.
Tao Y, Liu J, Li M, Wang H, Fan G, Xie X, Fu X, Su J
Journal of ethnopharmacology 2024 May 10;325:117641
Journal of ethnopharmacology 2024 May 10;325:117641
A unique circ_0067716/EIF4A3 double-negative feedback loop impacts malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene.
Zhao S, Xiao M, Li L, Zhang H, Shan M, Cui S, Zhang L, Zhang G, Wu S, Jin C, Yang J, Lu X
The Science of the total environment 2024 May 1;923:171349
The Science of the total environment 2024 May 1;923:171349
Cytotoxic withanolides from the stems and leaves of Physalis ixocarpa.
Xiang K, Liu Y, Zhu R, Xu Y, Sun D, Yang Y, Yan Y, Yang B, Li H, Chen L
Food chemistry 2024 May 1;439:138136
Food chemistry 2024 May 1;439:138136
Overcoming the Blood-Brain Tumor Barrier with Docetaxel-Loaded Mesoporous Silica Nanoparticles for Treatment of Temozolomide-Resistant Glioblastoma.
Hsu TI, Chen YP, Zhang RL, Chen ZA, Wu CH, Chang WC, Mou CY, Chan HW, Wu SH
ACS applied materials & interfaces 2024 May 1;16(17):21722-21735
ACS applied materials & interfaces 2024 May 1;16(17):21722-21735
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
The down-regulation of STC2 mRNA may serve as a biomarker for death from mechanical asphyxia.
Hu Y, Han L, Zhang H, Li W, Wu T, Ma J, Zhang D, Ma K, Xiao B, Yu Y, Xu H, Tian L, Liao X, Chen L
Legal medicine (Tokyo, Japan) 2024 Mar;67:102382
Legal medicine (Tokyo, Japan) 2024 Mar;67:102382
Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy.
Lin J, Wang L, Wu Y, Xiang Q, Zhao Y, Zheng X, Jiang S, Sun Z, Fan D, Li W
Experimental & molecular medicine 2024 Mar;56(3):747-759
Experimental & molecular medicine 2024 Mar;56(3):747-759
Notoginsenoside R1 attenuates bupivacaine induced neurotoxicity by activating Jak1/Stat3/Mcl1 pathway.
Yang Y, Wu J, Feng S, Yu H, Liu C, Wang S
Toxicology 2024 Mar;503:153740
Toxicology 2024 Mar;503:153740
14-3-3-η interacts with BCL-2 to protect human endothelial progenitor cells from ox-LDL-triggered damage.
Zhou H, Sun X, Dai Y, Wang X, Dai Z, Li X
Cell biology international 2024 Mar;48(3):290-299
Cell biology international 2024 Mar;48(3):290-299
Hypothermic machine perfusion reduces donation after circulatory death liver ischemia-reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway.
Peng S, Liang W, Liu Z, Ye S, Peng Z, Zhong Z, Ye Q
Human cell 2024 Mar;37(2):420-434
Human cell 2024 Mar;37(2):420-434
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Cao Y, Su H, Zeng J, Xie Y, Liu Z, Liu F, Qiu Y, Yi F, Lin J, Hammes HP, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Potential Effects of Orally Ingesting Polyethylene Terephthalate Microplastics on the Mouse Heart.
Lu T, Li D, Yuan X, Wang Z, Shao Z, Feng X, Yang C, Liu H, Zhang G, Wang Y, Liu X, Zhou L, Xu M
Cardiovascular toxicology 2024 Mar;24(3):291-301
Cardiovascular toxicology 2024 Mar;24(3):291-301
C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells.
Xia Z, Wei Z, Li X, Liu Y, Gu X, Huang S, Zhang X, Wang W
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167039
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167039
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Jing J, Wang J, Xiang X, Yin S, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer.
Shi MY, Wang Y, Shi Y, Tian R, Chen X, Zhang H, Wang K, Chen Z, Chen R
Genes & diseases 2024 Mar;11(2):978-992
Genes & diseases 2024 Mar;11(2):978-992
Enzymatically Bioactive Nucleus Pulposus Matrix Hydrogel Microspheres for Exogenous Stem Cells Therapy and Endogenous Repair Strategy to Achieve Disc Regeneration.
Peng Y, Chen X, Zhang Q, Liu S, Wu W, Li K, Lin H, Qing X, Xiao Y, Wang B, Quan D, Feng S, Rao Z, Bai Y, Shao Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2304761
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2304761
Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy.
Li Z, Zhang Y, Zhao B, Xue Q, Wang C, Wan S, Wang J, Chen X, Qi X
Veterinary research 2024 Mar 5;55(1):27
Veterinary research 2024 Mar 5;55(1):27
LncTCONS_00058568 is involved in the pathophysiologic processes mediated by P2X7R in the lower thoracic spinal cord after acute kidney injury.
Wang Y, Chen Z, Liu Q, Lv Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23563
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23563
The therapeutic effect of anti-CD19 antibody on DHEA-induced PCOS mice.
Wang T, Xiong X, Xiao N, Yan Y, Liu X, Xie Q, Su X, Chen M, Peng J, Wang S, Mei H, Lin G, Gong F, Cheng L
International immunopharmacology 2024 Mar 30;130:111711
International immunopharmacology 2024 Mar 30;130:111711
Long non-coding RNA LINC01554 overexpression suppresses viability, migration, and invasion of liver cancer cells through regulating miR-148b-3p/EIF4E3.
Ren X, Wang X, Song H, Zhang C, Yuan J, He J, Li J, Wang Z
Heliyon 2024 Mar 30;10(6):e27319
Heliyon 2024 Mar 30;10(6):e27319
A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection.
Xue M, Xing L, Yang Y, Shao M, Liao F, Xu F, Chen Y, Wang S, Chen B, Yao C, Gu G, Tong C
BMC cardiovascular disorders 2024 Mar 26;24(1):180
BMC cardiovascular disorders 2024 Mar 26;24(1):180
Electrospun nanofibrous mats loaded with gemcitabine and cisplatin suppress bladder tumor growth by improving the tumor immune microenvironment.
Wang J, Yin Y, Ren X, Wang S, Zhu Y
Journal of materials science. Materials in medicine 2024 Mar 25;35(1):21
Journal of materials science. Materials in medicine 2024 Mar 25;35(1):21
Exploring the hypoglycemic mechanism of chlorogenic acids from Pyrrosia petiolosa (Christ) Ching on type 2 diabetes mellitus based on network pharmacology and transcriptomics strategy.
He H, Wei Q, Chang J, Yi X, Yu X, Luo G, Li X, Yang W, Long Y
Journal of ethnopharmacology 2024 Mar 25;322:117580
Journal of ethnopharmacology 2024 Mar 25;322:117580
Evaluation on the Potential for Hepatotoxic Components from Herba Epimedii to Induce Apoptosis in HepG2 Cells and the Analysis of the Influence of Metabolism in Liver Microsomes.
Zhang L, Zhang C, Peng X, Guo Z, Yang S, Fu D
Molecules (Basel, Switzerland) 2024 Mar 19;29(6)
Molecules (Basel, Switzerland) 2024 Mar 19;29(6)
Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.
Huang Y, Wu Z, Peng Z, Liu A, Yuan W, Han D, Peng J
BMC cancer 2024 Mar 18;24(1):345
BMC cancer 2024 Mar 18;24(1):345
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
Hagi T, Vangveravong S, Takchi R, Gong Q, Goedegebuure SP, Tiriac H, Van Tine BA, Powell MA, Hawkins WG, Spitzer D
Scientific reports 2024 Mar 16;14(1):6373
Scientific reports 2024 Mar 16;14(1):6373
FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway.
Wang DX, Bao SY, Song NN, Chen WZ, Ding XQ, Walker RJ, Fang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23436
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23436
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Wang W, Zhou C, Ma Z, Zeng L, Wang H, Cheng X, Zhang C, Xue Y, Yuan Y, Li J, Hu L, Huang J, Luo T, Zheng L
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Pro-tumorigenic activity of PYCR1 in gastric cancer through regulating the PI3K/AKT signaling.
Xiao H, Huang J, Wu H, Li Y, Wang Y
Heliyon 2024 Mar 15;10(5):e26883
Heliyon 2024 Mar 15;10(5):e26883
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
Cen Q, Chen J, Guo J, Chen M, Wang H, Wu S, Zhang H, Xie X, Li Y
Journal of translational medicine 2024 Mar 14;22(1):278
Journal of translational medicine 2024 Mar 14;22(1):278
Effects of Dityrosine on Lactic Acid Metabolism in Mice Gastrocnemius Muscle During Endurance Exercise via the Oxidative Stress-Induced Mitochondria Damage.
Xia Q, Lan J, Pan Y, Wang Y, Song T, Yang Y, Tian X, Chen L, Gu Z, Ding YY
Journal of agricultural and food chemistry 2024 Mar 13;72(10):5269-5282
Journal of agricultural and food chemistry 2024 Mar 13;72(10):5269-5282
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.
Ni F, Wang F, Li J, Liu Y, Sun X, Chen J, Li J, Zhang Y, Jin J, Ye X, Tu M, Chen J, Chen C, Zhang D
Biology of reproduction 2024 Mar 13;110(3):615-631
Biology of reproduction 2024 Mar 13;110(3):615-631
ATP5me alleviates high glucose-induced myocardial cell injury.
Hou Q, Yan F, Li X, Liu H, Yang X, Dong X
International immunopharmacology 2024 Mar 10;129:111626
International immunopharmacology 2024 Mar 10;129:111626
Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.
Li W, Zhang W, Zhang D, Shi C, Wang Y
International immunopharmacology 2024 Mar 10;129:111612
International immunopharmacology 2024 Mar 10;129:111612
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
Inhibition of ROS/caspase-3/GSDME-mediated pyroptosis alleviates high glucose-induced injury in AML-12 cells.
Wang X, Ye S, Tong L, Gao J, Zhang Y, Qin Y
Toxicology in vitro : an international journal published in association with BIBRA 2024 Jun;98:105840
Toxicology in vitro : an international journal published in association with BIBRA 2024 Jun;98:105840
GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis.
Zhou T, Zhang L, He L, Lan Y, Ding L, Li L, Wang Z
Molecular neurobiology 2024 Jun;61(6):3369-3383
Molecular neurobiology 2024 Jun;61(6):3369-3383
Celastrol enhances the viability of random-pattern skin flaps by regulating autophagy through the AMPK-mTOR-TFEB axis.
Gu M, Li C, Deng Q, Chen X, Lei R
Phytotherapy research : PTR 2024 Jun;38(6):3020-3036
Phytotherapy research : PTR 2024 Jun;38(6):3020-3036
Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis.
Chen J, Zhang T, Luo Q, Wang R, Dai Y, Chen Z, Zhang C, Chen X, Wu G
Molecular medicine reports 2024 Jun;29(6)
Molecular medicine reports 2024 Jun;29(6)
Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury.
Lin HY, Liang CJ, Yang MY, Chen PL, Wang TM, Chen YH, Shih YH, Liu W, Chiu CC, Chiang CK, Lin CS, Lin HC
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):620-634
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):620-634
Cisplatin-activated and hemoglobin-mediated injectable hydrogel system for antitumor chemodynamic and chemotherapy.
Tsen HT, Sun TC, Lai TK, Huang WY, Wang HC, Lu TT, Wang TW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116713
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116713
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Sheng X, Wang MM, Zhang GD, Su Y, Fang HB, Yu ZH, Su Z
Bioorganic chemistry 2024 Jun;147:107325
Bioorganic chemistry 2024 Jun;147:107325
The mechanism of curcumin to protect mouse ovaries from oxidative damage by regulating AMPK/mTOR mediated autophagy.
Duan H, Yang S, Yang S, Zeng J, Yan Z, Zhang L, Ma X, Dong W, Zhang Y, Zhao X, Hu J, Xiao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155468
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155468
JinChan YiShen TongLuo Formula ameliorate mitochondrial dysfunction and apoptosis in diabetic nephropathy through the HIF-1α-PINK1-Parkin pathway.
Qiyan Zheng, Zhang X, Guo J, Wang Y, Jiang Y, Li S, Liu YN, Liu WJ
Journal of ethnopharmacology 2024 Jun 28;328:117863
Journal of ethnopharmacology 2024 Jun 28;328:117863
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Fei S, Ma Y, Zhou B, Chen X, Zhang Y, Yue K, Li Q, Gui Y, Xiang T, Liu J, Yang B, Wang L, Huang X
International journal of pharmaceutics 2024 Jun 25;659:124261
International journal of pharmaceutics 2024 Jun 25;659:124261
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC.
Li JJ, Ru ZX, Yang X, Sun JX, Wu YM, Yang XY, Hou BY, Xue B, Ding C, Qiao H
Journal of translational medicine 2024 Jun 20;22(1):586
Journal of translational medicine 2024 Jun 20;22(1):586
Bradykinin protects nucleus pulposus cells from tert-butyl hydroperoxide-induced damage and delays intervertebral disc degeneration.
Qiu X, Ma C, Luo Z, Zhang Y, Kang J, Zhu D, Wang Z, Li L, Wei Z, Wang Z, Kang X
International immunopharmacology 2024 Jun 15;134:112161
International immunopharmacology 2024 Jun 15;134:112161
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Chen B, Fu W, Jie C, Zhang G, Li Z, Liu Y, Zhou S
Molecular medicine reports 2024 Jul;30(1)
Molecular medicine reports 2024 Jul;30(1)
Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway.
Wang C, Cui C, Xie X, Chen B, Feng L, Jiang P
Psychopharmacology 2024 Jul;241(7):1329-1343
Psychopharmacology 2024 Jul;241(7):1329-1343
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
Wu J, Wang C, Sun S, Ren T, Pan L, Liu H, Hou S, Wu S, Yan X, Zhang J, Zhao X, Liu W, Zhu S, Wei S, Zhang C, Jia X, Zhang Q, Yu Z, Zhuo Y, Zhao Q, Yang C, Wang N
Protein & cell 2024 Jul 20;15(8):594-611
Protein & cell 2024 Jul 20;15(8):594-611
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress.
Li M, Tang S, Velkov T, Shen J, Dai C
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124145
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124145
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.
Xi Y, Feng Z, Xia T, Hong Y, Wu J, Chen J, Ge Y, Xiao H
Life sciences 2024 Jul 1;348:122694
Life sciences 2024 Jul 1;348:122694
Melatonin Exerts an Anti-Panoptoic Role in Spinal Cord Ischemia-Reperfusion Injured Rats.
Xie L, Wu H, Shi W, Zhang J, Huang X, Yu T
Advanced biology 2024 Jan;8(1):e2300424
Advanced biology 2024 Jan;8(1):e2300424
Oridonin suppresses the growth of glioblastoma cells via inhibiting Hippo/YAP axis.
Wang C, Zhang Y, Jiang Q, Chen S, Zhang L, Qiu H
Archives of biochemistry and biophysics 2024 Jan;751:109845
Archives of biochemistry and biophysics 2024 Jan;751:109845
Mycobacterium tuberculosis PE_PGRS45 (Rv2615c) Promotes Recombinant Mycobacteria Intracellular Survival via Regulation of Innate Immunity, and Inhibition of Cell Apoptosis.
Xu T, Wang C, Li M, Wei J, He Z, Qian Z, Wang X, Wang H
Journal of microbiology (Seoul, Korea) 2024 Jan;62(1):49-62
Journal of microbiology (Seoul, Korea) 2024 Jan;62(1):49-62
Selenomethionine protects the liver from dietary deoxynivalenol exposure via Nrf2/PPARγ-GPX4-ferroptosis pathway in mice.
Fan S, Lin L, Li P, Tian H, Shen J, Zhou L, Zhao Q, Zhang J, Qin Y, Tang C
Toxicology 2024 Jan;501:153689
Toxicology 2024 Jan;501:153689
Vitamin C enhances the sensitivity of osteosarcoma to arsenic trioxide via inhibiting aerobic glycolysis.
Liu Y, Yue J, Ren Z, He M, Wang A, Xie J, Li T, Liu G, He X, Ge S, Yuan Y, Yang L
Toxicology and applied pharmacology 2024 Jan;482:116798
Toxicology and applied pharmacology 2024 Jan;482:116798
CircNEK6 promotes the progression of pancreatic ductal adenocarcinoma through targeting miR-503/CCND1 axis.
Shao Z, Chen X, Qiu H, Xu M, Wen X, Chen Z, Liu Z, Ding X, Zhang L
Translational oncology 2024 Jan;39:101810
Translational oncology 2024 Jan;39:101810
Diminazene aceturate-induced cytotoxicity is associated with the deregulation of cell cycle signaling and downregulation of oncogenes Furin, c-MYC, and FOXM1 in human cervical carcinoma Hela cells.
Gharbaran R, Sayibou Z, Atamturktur S, Ofosu-Mensah JJ, Soto J, Boodhan N, Kolya S, Onwumere O, Chang L, Somenarain L, Redenti S
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23527
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23527
IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway.
Liu Z, Feng C, Li C, He T, Wu G, Fu C, Li H, Shen M, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23332
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23332
N-n-butyl haloperidol iodide mediates cardioprotection via regulating AMPK/FoxO1 signalling.
Lu B, Wu Z, He W, Feng Z, Liao J, Wang B, Zhang Y, Gao F, Shi G, Zheng F
Journal of cellular and molecular medicine 2024 Jan;28(2):e18049
Journal of cellular and molecular medicine 2024 Jan;28(2):e18049
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Wang C, Yi T, Li X, Cui J, Li B, Qin Y, Tang S, Zhang J
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Wang W, Yu R, Wu C, Li Q, Chen J, Xiao Y, Chen H, Song J, Ji M, Zuo Z
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
In vitro anticancer effect of azithromycin targeting hypoxic lung cancer cells via the inhibition of mitophagy.
Toriyama K, Okuma T, Abe S, Nakamura H, Aoshiba K
Oncology letters 2024 Jan;27(1):12
Oncology letters 2024 Jan;27(1):12
pH-driven preparation of pea protein isolate-curcumin nanoparticles effectively enhances antitumor activity.
Ren J, Wu H, Lu Z, Qin Q, Jiao X, Meng G, Liu W, Li G
International journal of biological macromolecules 2024 Jan;256(Pt 1):128383
International journal of biological macromolecules 2024 Jan;256(Pt 1):128383
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
Zhao D, He J, Zhao X, Sheng X, Feng Z, Wang X, Zhang C, Wang S, Geng B, Xia Y
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Xia K, Guo J, Yu B, Wang T, Qiu Q, Chen Q, Qiu T, Zhou J, Zheng S
Free radical biology & medicine 2024 Jan;210:378-389
Free radical biology & medicine 2024 Jan;210:378-389
Methylglyoxal accumulation contributes to accelerated brain aging in spontaneously hypertensive rats.
Zhang WY, Zhao CM, Wang CS, Xie X, Li YQ, Chen BB, Feng L, Jiang P
Free radical biology & medicine 2024 Jan;210:108-119
Free radical biology & medicine 2024 Jan;210:108-119
hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia-reperfusion injury through the KEAP1/Nrf2/HO-1 signaling.
Hou Z, Yang F, Chen K, Wang Y, Qin J, Liang F
Drug delivery and translational research 2024 Jan;14(1):143-157
Drug delivery and translational research 2024 Jan;14(1):143-157
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Liu Y, Zhou C, Tan J, Wu T, Pan C, Liu J, Cheng X
Chemical biology & drug design 2024 Jan;103(1):e14382
Chemical biology & drug design 2024 Jan;103(1):e14382
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
Polyphyllin II (PPII) Enhances the Sensitivity of Multidrug-resistant A549/DDP Cells to Cisplatin by Modulating Mitochondrial Energy Metabolism.
Peng L, Yang R, Wang Z, Jian H, Tan X, Li J, He Z, Huang R, Zeng P, Gao W
In vivo (Athens, Greece) 2024 Jan-Feb;38(1):213-225
In vivo (Athens, Greece) 2024 Jan-Feb;38(1):213-225
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Sun J, Zhang W
Heliyon 2024 Jan 30;10(2):e24575
Heliyon 2024 Jan 30;10(2):e24575
METTL1 mediated tRNA m(7)G modification promotes leukaemogenesis of AML via tRNA regulated translational control.
Zhao P, Xia L, Chen D, Xu W, Guo H, Xu Y, Yan B, Wu X, Li Y, Zhang Y, Zhang X
Experimental hematology & oncology 2024 Jan 24;13(1):8
Experimental hematology & oncology 2024 Jan 24;13(1):8
Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis.
Hu X, Li X, Wu S, Jiang X, Chen G, Hu Y, Sun J, Bai W
European journal of pharmacology 2024 Jan 15;963:176237
European journal of pharmacology 2024 Jan 15;963:176237
Loganin protects against myocardial ischemia-reperfusion injury by modulating oxidative stress and cellular apoptosis via activation of JAK2/STAT3 signaling.
Xia B, Ding J, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
International journal of cardiology 2024 Jan 15;395:131426
International journal of cardiology 2024 Jan 15;395:131426
E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis.
Huang Y, Chen T, Jiang M, Xiong C, Mei C, Nie J, Zhang Q, Zhu Q, Huang X, Zhang X, Li Y
Cell death & disease 2024 Jan 11;15(1):29
Cell death & disease 2024 Jan 11;15(1):29
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Lv Y, Liu Z, Deng L, Xia S, Mu Q, Xiao B, Xiu Y, Liu Z
Scientific reports 2024 Jan 10;14(1):1009
Scientific reports 2024 Jan 10;14(1):1009
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Zhu M, Yan M, Musa M, Li Y, Zhang Y, Zou X
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Zhang B, Huang C, Xu D, Huang K, Li Y, Jiao L, Fu B, Li S, Li Y
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.
Gan X, Wang F, Luo J, Zhao Y, Wang Y, Yu C, Chen J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624
Chemoproteomics Reveals Glaucocalyxin A Induces Mitochondria-Dependent Apoptosis of Leukemia Cells via Covalently Binding to VDAC1.
An Y, Zhang Q, Chen Y, Xia F, Wong YK, He H, Hao M, Tian J, Zhang X, Luo P, Wang J
Advanced biology 2024 Feb;8(2):e2300538
Advanced biology 2024 Feb;8(2):e2300538
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Lu T, Ding L, Zheng X, Li Y, Wei W, Liu W, Tao J, Xue X
Molecular neurobiology 2024 Feb;61(2):753-771
Molecular neurobiology 2024 Feb;61(2):753-771
Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines.
Li L, Xin L, Yang X, Zou Z
Journal of molecular histology 2024 Feb;55(1):97-108
Journal of molecular histology 2024 Feb;55(1):97-108
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells.
Zhao YY, Li J, Wang HQ, Zheng HB, Ma SW, Zhou GZ
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23642
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23642
Axonal injury mediated by neuronal p75NTR/TRAF6/JNK pathway contributes to cognitive impairment after repetitive mTBI.
Liu G, He M, Wu C, Lv P, Sun H, Wang H, Xin X, Liao H
Experimental neurology 2024 Feb;372:114618
Experimental neurology 2024 Feb;372:114618
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Chen B, Zhao Y, Xu S, Jiang F, Nie Y, Tang A, Zhou Q
Annals of hematology 2024 Feb;103(2):533-544
Annals of hematology 2024 Feb;103(2):533-544
Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation.
He Y, Liu F, He M, Long F, Hu D, Chen J, Fang M, Wang Z
BMC complementary medicine and therapies 2024 Feb 29;24(1):108
BMC complementary medicine and therapies 2024 Feb 29;24(1):108
Resveratrol-laden mesoporous silica nanoparticles regulate the autophagy and apoptosis via ROS-mediated p38-MAPK/HIF-1a /p53 signaling in hypertrophic scar fibroblasts.
Zuo J, Ma S
Heliyon 2024 Feb 29;10(4):e24985
Heliyon 2024 Feb 29;10(4):e24985
ADAR1 Inhibits Macrophage Apoptosis and Alleviates Sepsis-induced Liver Injury Through miR-122/BCL2A1 Signaling.
Liu S, Xie J, Duan C, Zhao X, Feng Z, Dai Z, Luo X, Li Y, Yang M, Zhuang R, Li J, Yin W
Journal of clinical and translational hepatology 2024 Feb 28;12(2):134-150
Journal of clinical and translational hepatology 2024 Feb 28;12(2):134-150
Valproic acid regulates the miR-155/Jarid2 axis by affecting miR-155 promoter methylation in glioma.
Wang R, Chen Y, Kuang W, Jiang W, Zeng W, Chen Y, Liu Z
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):174-183
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):174-183
Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury.
Ye T, Chen C, Wang D, Huang C, Yan Z, Chen Y, Jin X, Wang X, Ding X, Shen C
Nature communications 2024 Feb 23;15(1):1682
Nature communications 2024 Feb 23;15(1):1682
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.
Duan S, Li X, Han J, Yang Y, Luo R, Cai Y, Li X, Zheng Q, Guo J, Liu R
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
Ge W, Yuan G, Wang D, Dong L
Scientific reports 2024 Feb 15;14(1):3783
Scientific reports 2024 Feb 15;14(1):3783
Cold atmospheric plasma stabilizes mismatch repair for effective, uniform treatment of diverse colorectal cancer cell types.
He Y, Lu F, Jiang C, Gong F, Wu Z, Ostrikov K
Scientific reports 2024 Feb 13;14(1):3599
Scientific reports 2024 Feb 13;14(1):3599
Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells.
Zhang F, Hao Y, Yang N, Liu M, Luo Y, Zhang Y, Zhou J, Liu H, Li J
BMC cancer 2024 Feb 12;24(1):198
BMC cancer 2024 Feb 12;24(1):198
Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression.
Sun B, Lin L, Yao T, Yao J, Zhang G, Li Y, Li C
Journal of ethnopharmacology 2024 Feb 10;320:117396
Journal of ethnopharmacology 2024 Feb 10;320:117396
Orthosiphon aristatus (Blume) Miq. Extracts attenuate Alzheimer-like pathology through anti-inflammatory, anti-oxidative, and β-amyloid inhibitory activities.
Chiang KH, Cheng TJ, Kan WC, Wang HY, Li JC, Cai YL, Cheng CH, Liu YC, Chang CY, Chuu JJ
Journal of ethnopharmacology 2024 Feb 10;320:117132
Journal of ethnopharmacology 2024 Feb 10;320:117132
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Zhao L, Miao H, Quan M, Wang S, Zhang Y, Zhou H, Zhang X, Lin Z, Piao J
Chemico-biological interactions 2024 Feb 1;389:110866
Chemico-biological interactions 2024 Feb 1;389:110866
Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf-κb pathway.
Si Y, Liu L, Zhang Y, Li H, Zhao T, Liu S, Sun X, Cheng J, Lu H
Renal failure 2024 Dec;46(1):2330629
Renal failure 2024 Dec;46(1):2330629
miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2.
Xia M, Chen J, Hu Y, Qu B, Bu Q, Shen H
Cancer biology & therapy 2024 Dec 31;25(1):2315651
Cancer biology & therapy 2024 Dec 31;25(1):2315651
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Yu Z, Li P, Gao D, Hu Y, Xia F, Liu L, Liu J, Liu W, Zhang H
Immunologic research 2024 Aug;72(4):797-810
Immunologic research 2024 Aug;72(4):797-810
The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.
Zhu F, Liu H, Cao Y, Dai B, Wu H, Li W
European journal of nutrition 2024 Aug;63(5):1945-1959
European journal of nutrition 2024 Aug;63(5):1945-1959
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Lv S, Jiang H, Yu L, Zhang Y, Sun L, Xu J
Journal of molecular histology 2024 Aug;55(4):391-401
Journal of molecular histology 2024 Aug;55(4):391-401
Apoptosis and pyroptosis in the nasal mucosa of Syrian hamster during SARS-CoV-2 infection and reinfection.
Li H, Zhao X, Zhang X, Zheng H, Wang Y, Hou J, Li J, Zhao Y, Peng S, Li Y, Zhang X, Zhang Y, Yang J, Zhang Z, Shi H, Liu L
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1246-1259
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1246-1259
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
Zhan XZ, Luo P, Zhang C, Zhang LJ, Shen X, Jiang DL, Liu WJ
Animal reproduction science 2024 Aug;267:107540
Animal reproduction science 2024 Aug;267:107540
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Yue C, Lu W, Fan S, Huang Z, Yang J, Dong H, Zhang X, Shang Y, Lai W, Li D, Dong T, Yuan A, Wu J, Kang L, Hu Y
Nature nanotechnology 2024 Aug;19(8):1203-1215
Nature nanotechnology 2024 Aug;19(8):1203-1215
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Cao H, Zhao L, Yuan Y, Liao C, Zeng W, Li A, Huang Q, Zhao Y, Fan Y, Jiang L, Song D, Li S, Zhang B
Journal of cardiovascular translational research 2024 Aug;17(4):910-922
Journal of cardiovascular translational research 2024 Aug;17(4):910-922
Bacillus subtilis alleviates excessive apoptosis of intestinal epithelial cells in intrauterine growth restriction suckling piglets via the members of Bcl-2 and caspase families.
Xie Z, Yun Y, Yu G, Zhang X, Zhang H, Wang T, Zhang L
Journal of the science of food and agriculture 2024 Aug 30;104(11):6924-6932
Journal of the science of food and agriculture 2024 Aug 30;104(11):6924-6932
Seliciclib alleviates ulcerative colitis by inhibiting ferroptosis and improving intestinal inflammation.
Song Y, Song Q, Tan F, Wang Y, Li C, Liao S, Yu K, Mei Z, Lv L
Life sciences 2024 Aug 15;351:122794
Life sciences 2024 Aug 15;351:122794
Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.
Nie QY, Yang GM, Zhang P, Dong WJ, Jing D, Hou ZP, Peng YX, Yu Y, Li LH, Hong SJ
Brain research 2024 Aug 15;1837:148973
Brain research 2024 Aug 15;1837:148973
Leonurus japonicus Houtt. modulates neuronal apoptosis in intracerebral hemorrhage: Insights from network pharmacology and molecular docking.
Wu JW, Gao W, Shen LP, Chen YL, Du SQ, Du ZY, Zhao XD, Lu XJ
Journal of ethnopharmacology 2024 Aug 10;330:118223
Journal of ethnopharmacology 2024 Aug 10;330:118223
HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation.
Nan K, Zhong Z, Yue Y, Zhou W, Sun X, Shen Y, Qu M, Chen Z, Gu J, Sun C, Sun X, Lu L, Zhang J, Miao C, Sun M
Digestive diseases and sciences 2024 Apr;69(4):1214-1227
Digestive diseases and sciences 2024 Apr;69(4):1214-1227
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis.
Wang W, Chen XK, Zhou L, Wang F, He YJ, Lu BJ, Hu ZG, Li ZX, Xia XW, Wang WE, Zeng CY, Li LP
Acta pharmacologica Sinica 2024 Apr;45(4):728-737
Acta pharmacologica Sinica 2024 Apr;45(4):728-737
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Wang N, Guo W, Liu T, Chen X, Lin M
Biotechnology & genetic engineering reviews 2024 Apr;40(1):519-539
Biotechnology & genetic engineering reviews 2024 Apr;40(1):519-539
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Lin M, Xiao Y, Dai Y, Mao Y, Xu L, Zhang Q, Chen Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1.
Yang Y, Zhang J, Lv M, Cui N, Shan B, Sun Q, Yan L, Zhang M, Zou C, Yuan J, Xu D
Nature cell biology 2024 Apr;26(4):567-580
Nature cell biology 2024 Apr;26(4):567-580
A coumarin-furoxan hybrid as novel nitric oxide donor induced cell apoptosis and ferroptosis in NSCLC by promoting S-nitrosylation of STAT3 and negative regulation of JAK2-STAT3 pathway.
Cao F, Li M, Wang W, Yi Y, Chen Y, Liu H
Biochemical pharmacology 2024 Apr;222:116068
Biochemical pharmacology 2024 Apr;222:116068
PGC-1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons.
Chen N, Zhan RN, Liu DQ, Zhang Y, Tian YK, Zhou YQ
Biochemical pharmacology 2024 Apr;222:116053
Biochemical pharmacology 2024 Apr;222:116053
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Wu H, Qu L, Bai X, Zhu C, Liu Y, Duan Z, Liu H, Fu R, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Yang Y, Zhou M, Huang Y, Ye X, Mo Y, Huang Y, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis.
Guo Q, Zhao M, Wang Q, Lu T, Luo P, Chen L, Xia F, Pang H, Shen S, Cheng G, Dai C, Meng Y, Zhong T, Qiu C, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116304
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116304
Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3.
Li Q, Shi M, Ang Y, Yu P, Wan B, Lin B, Chen W, Yue Z, Shi Y, Liu F, Wang H, Duan M, Long Y, Bao H
Molecular immunology 2024 Apr;168:64-74
Molecular immunology 2024 Apr;168:64-74
Regulatory mechanism of perinatal nonylphenol exposure on cardiac mitochondrial autophagy and the PINK1/Parkin signaling pathway in male offspring rats.
Yang X, Xu J, Xu Y, Wang C, Lin F, Yu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155434
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155434
Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells.
Hu W, Sun J, Zhang Y, Chen T, He F, Zhao H, Tan W, Wang Z, Ouyang J, Tang Z, He J, Wang J, Li J, Zeng X, Xia J
Annals of hematology 2024 Apr;103(4):1293-1303
Annals of hematology 2024 Apr;103(4):1293-1303
NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16.
Guo D, Zhang M, Wei T, Zhang X, Shi X, Tang H, Ding M, Li J, Zhang S, Guo W
Cellular and molecular life sciences : CMLS 2024 Apr 6;81(1):167
Cellular and molecular life sciences : CMLS 2024 Apr 6;81(1):167
Sodium sulfite triggered hepatic apoptosis, necroptosis, and pyroptosis by inducing mitochondrial damage in mice and AML-12 cells.
Liu M, Lu J, Hu J, Chen Y, Deng X, Wang J, Zhang S, Guo J, Li W, Guan S
Journal of hazardous materials 2024 Apr 5;467:133719
Journal of hazardous materials 2024 Apr 5;467:133719
LINC00942 Alleviates NaAsO(2)-induced Apoptosis by Promoting GSH Synthesis Through Targeting miR-214-5p.
Ma M, Zhang J, Li S, Zhang M, Chen W, Li L, Li S
Biological trace element research 2024 Apr 5;
Biological trace element research 2024 Apr 5;
Dynamic role of CUL4B in radiation-induced intestinal injury-regeneration.
Guo B, Huo X, Xie X, Zhang X, Lian J, Zhang X, Gong Y, Dou H, Fan Y, Mao Y, Wang J, Hu H
Scientific reports 2024 Apr 30;14(1):9906
Scientific reports 2024 Apr 30;14(1):9906
Exploring the effective compounds and potential mechanisms of Shengxian Decoction against coronary heart disease by UPLC-Q-TOF/MS and network pharmacology analysis.
Zhou HM, Yue SJ, Wang WX, Zhang Q, Xu DQ, Li JJ, Tang YP, Yang XY
Heliyon 2024 Apr 30;10(8):e29558
Heliyon 2024 Apr 30;10(8):e29558
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361
Heliyon 2024 Apr 30;10(8):e29361
Targeting IDH1-Mutated Oligodendroglioma with Acid Ceramidase Inhibitors.
Muley H, Dowdy T, Zaibaq F, Karadimov G, Li A, Song H, Zhang M, Zhang W, Wong Z, Zhang L, Lita A, Larion M
bioRxiv : the preprint server for biology 2024 Apr 29;
bioRxiv : the preprint server for biology 2024 Apr 29;
Induction of IFIT1/IFIT3 and inhibition of Bcl-2 orchestrate the treatment of myeloma and leukemia via pyroptosis.
He Y, Jiang S, Cui Y, Liang J, Zhong Y, Sun Y, Moran MF, Huang Z, He G, Mao X
Cancer letters 2024 Apr 28;588:216797
Cancer letters 2024 Apr 28;588:216797
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats.
Wang X, Fu Y, Yang X, Chen Y, Zeng N, Hu S, Ouyang S, Pan X, Wu S
Scientific reports 2024 Apr 27;14(1):9723
Scientific reports 2024 Apr 27;14(1):9723
Diphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects.
Shi Y, Huang D, Song C, Cao R, Wang Z, Wang D, Zhao L, Xu X, Lu C, Xiong F, Zhao H, Li S, Zhou Q, Luo S, Hu D, Zhang Y, Wang C, Shen Y, Su W, Wu Y, Schmitz K, Wei S, Song W
Nature communications 2024 Apr 26;15(1):3301
Nature communications 2024 Apr 26;15(1):3301
Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
Song T, Yu Z, Shen Q, Xu Y, Hu H, Liu J, Zeng K, Lei J, Yu L
Cancers 2024 Apr 23;16(9)
Cancers 2024 Apr 23;16(9)
Discovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation.
Gao E, Wang Y, Fan GL, Xu G, Wu ZY, Liu ZJ, Liu JC, Mao LF, Hou X, Li S
Scientific reports 2024 Apr 22;14(1):9223
Scientific reports 2024 Apr 22;14(1):9223
B-Myb deficiency boosts bortezomib-induced immunogenic cell death in colorectal cancer.
Hui YJ, Yu TT, Li LG, Peng XC, Di MJ, Liu H, Gu WL, Li TF, Zhao KL, Wang WX
Scientific reports 2024 Apr 2;14(1):7733
Scientific reports 2024 Apr 2;14(1):7733
Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling.
Huang W, Yang S, Deng M, Luo R, Liang H, Shen Y, Yang B, Xu C, Hou Y
Functional & integrative genomics 2024 Apr 18;24(3):77
Functional & integrative genomics 2024 Apr 18;24(3):77
Tumor Supplying Artery Injection of Liposome@Sunitinib Could Effectively Inhibit the Progression of Kidney Tumor.
Fu Q, Li G, Wang L, Yin C, Yi B, Huang Y, Su Q, Zhang Z, Zhu J
ACS applied materials & interfaces 2024 Apr 16;
ACS applied materials & interfaces 2024 Apr 16;
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
zDHHC3-mediated S-palmitoylation of SLC9A2 regulates apoptosis in kidney clear cell carcinoma.
Zhang X, Hou J, Zhou G, Wang H, Wu Z
Journal of cancer research and clinical oncology 2024 Apr 15;150(4):194
Journal of cancer research and clinical oncology 2024 Apr 15;150(4):194
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Wang N, Zhang Q, Wang Z, Liu Y, Yang S, Zhao X, Peng J
Carbohydrate polymers 2024 Apr 1;329:121795
Carbohydrate polymers 2024 Apr 1;329:121795
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Cao W, Lu X, Zhong C, Wu J
Nutrition and cancer 2023;75(3):980-991
Nutrition and cancer 2023;75(3):980-991
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Zhang T, Cao W, Sun H, Yu D, Zhong C
Nutrition and cancer 2023;75(3):971-979
Nutrition and cancer 2023;75(3):971-979
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Gao H, Yin C, Li C, Li Y, Shi D, Fan X, Yao F, Wu W, Li J
Current research in food science 2023;6:100519
Current research in food science 2023;6:100519
Hepatocellular SETDB1 Regulates Hepatic Ischemia-Reperfusion Injury through Targeting Lysine Methylation of ASK1 Signal.
Xia K, Wang T, Chen Z, Guo J, Yu B, Chen Q, Qiu T, Zhou J, Zheng S
Research (Washington, D.C.) 2023;6:0256
Research (Washington, D.C.) 2023;6:0256
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Hao Z, Zhang Z, Zhao Y, Wang D
The American journal of Chinese medicine 2023;51(2):355-372
The American journal of Chinese medicine 2023;51(2):355-372
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
Zhou H, Xu L, Shi Y, Gu S, Wu N, Liu F, Huang Y, Qian Z, Xue W, Wang X, Chen F
Biological & pharmaceutical bulletin 2023;46(1):42-51
Biological & pharmaceutical bulletin 2023;46(1):42-51
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression.
Liu N, Fan Y, Li Y, Zhang Y, Li J, Wang Y, Wang Z, Liu Y, Li Y, Kang Z, Peng Y, Ru Z, Yang M, Feng C, Wang Y, Yang X
Current neuropharmacology 2023;21(12):2550-2562
Current neuropharmacology 2023;21(12):2550-2562
MiR-125b-5p/STAT3 Axis Regulates Drug Resistance in Osteosarcoma Cells by Acting on ABC Transporters.
Yang Y, Chen Y, Liu J, Zhang B, Yang L, Xue J, Zhang Z, Qin L, Bian R
Stem cells international 2023;2023:9997676
Stem cells international 2023;2023:9997676
A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways.
Duan SF, Zhang MM, Dong Q, Yang B, Liu W, Zhang X, Yu HL, Zhang SH, Khan NH, Wu DD, Zhang XJ, Cen J
Journal of oncology 2023;2023:8456852
Journal of oncology 2023;2023:8456852
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Liu CJ, Ma ZZ, Gong WZ, Mao XH, Wen HQ, Wang XH
Journal of oncology 2023;2023:5141836
Journal of oncology 2023;2023:5141836
Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage.
Du N, Zhang B, Zhang Y
Canadian respiratory journal 2023;2023:4533504
Canadian respiratory journal 2023;2023:4533504
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Zou R, Wang S, Cai H, Wang Y, Wang C
Cardiovascular therapeutics 2023;2023:2108584
Cardiovascular therapeutics 2023;2023:2108584
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
Luo Y, Zhao Y, Lai J, Wei L, Zhou G, Yu Y, Liu J
BioMed research international 2023;2023:1176232
BioMed research international 2023;2023:1176232
Melatonin Ameliorates Ovarian Hyperstimulation Syndrome (OHSS) through SESN2 Regulated Antiapoptosis.
Zheng M, Liu M, Zhang C
Obstetrics and gynecology international 2023;2023:1121227
Obstetrics and gynecology international 2023;2023:1121227
Autophagy Inhibition Contributes to Apoptosis of PLK4 Downregulation-induced Dormant Cells in Colorectal Cancer.
Tian X, He Y, Qi L, Liu D, Zhou D, Liu Y, Gong W, Han Z, Xia Y, Li H, Wang J, Zhu K, Chen L, Guo H, Zhao Q
International journal of biological sciences 2023;19(9):2817-2834
International journal of biological sciences 2023;19(9):2817-2834
Notoginsenoside R1 attenuates brain injury in rats with traumatic brain injury: Possible mediation of apoptosis via ERK1/2 signaling pathway.
Pei X, Zhang L, Liu D, Wu Y, Li X, Cao Y, Du X
PloS one 2023;18(12):e0295903
PloS one 2023;18(12):e0295903
Effect of matrine in MAC-T cells and their transcriptome analysis: A basic study.
Zhang Z, Yang Y, Yan L, Wan X, Sun K, Gou H, Ding J, Peng J, Liu G, Wang C
PloS one 2023;18(1):e0280905
PloS one 2023;18(1):e0280905
WTAP affects intracranial aneurysm progression by regulating m6A methylation modification.
Yuan X, Bao Q, Lu B, Xiang C, Hou X, Wei W
Open medicine (Warsaw, Poland) 2023;18(1):20230818
Open medicine (Warsaw, Poland) 2023;18(1):20230818
Bacterial lipoprotein plays an important role in the macrophage autophagy and apoptosis induced by Salmonella typhimurium and Staphylococcus aureus.
Jiang S, He J, Zhang L, Zhao Q, Zhao S
Open life sciences 2023;18(1):20220739
Open life sciences 2023;18(1):20220739
HK2 contributes to the proliferation, migration, and invasion of diffuse large B-cell lymphoma cells by enhancing the ERK1/2 signaling pathway.
Zhao H, Xiang G, Shao T, Wang M, Dai W
Open life sciences 2023;18(1):20220726
Open life sciences 2023;18(1):20220726
Solanine Represses Gastric Cancer Growth by Mediating Autophagy Through AAMDC/MYC/ATF4/Sesn2 Signaling Pathway.
Tang X, Guo Y, Zhang S, Wang X, Teng Y, Jin Q, Jin Q, Shen W, Wang R
Drug design, development and therapy 2023;17:389-402
Drug design, development and therapy 2023;17:389-402
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease.
Tang C, Deng X, Qu J, Miao Y, Tian L, Zhang M, Li X, Sun B, Chen L
Drug design, development and therapy 2023;17:1503-1514
Drug design, development and therapy 2023;17:1503-1514
Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice.
Gai C, Xing X, Song Y, Zhao Y, Jiang Z, Cheng Y, Xiao Y, Wang Z
Drug design, development and therapy 2023;17:1175-1189
Drug design, development and therapy 2023;17:1175-1189
Electroacupuncture alleviates ciliary muscle cell apoptosis in lens-induced myopic guinea pigs through inhibiting the mitochondrial signaling pathway.
Yang ZH, Hao JW, Liu JP, Bao B, Li TL, Wu QX, He MG, Bi HS, Guo DD
International journal of ophthalmology 2023;16(12):1942-1951
International journal of ophthalmology 2023;16(12):1942-1951
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Duan J, Zhang Z, Du J, Zhang J, Li M, Li C
OncoTargets and therapy 2023;16:425-440
OncoTargets and therapy 2023;16:425-440
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y
Journal of Cancer 2023;14(4):611-627
Journal of Cancer 2023;14(4):611-627
Artesunate, as an Hsp90 inhibitor, inhibits the proliferation of Burkitt's lymphoma cells by inhibiting AKT and ERK.
Yuan-Ce L, Qi Z, Hong-Yang Z, Yan-Wen W, Yu-Mei S, Bi-Juan Y, Jun-Lin Y
Frontiers in pharmacology 2023;14:1218467
Frontiers in pharmacology 2023;14:1218467
Uncovering the active constituents and mechanisms of Rujin Jiedu powder for ameliorating LPS-induced acute lung injury using network pharmacology and experimental investigations.
Ma Y, Xu H, Chen G, Liu W, Ma C, Meng J, Yuan L, Hua X, Ge G, Lei M
Frontiers in pharmacology 2023;14:1186699
Frontiers in pharmacology 2023;14:1186699
Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway.
Liu Y, Mo J, Liang F, Jiang S, Xiong J, Meng X, Mo Z
Frontiers in pharmacology 2023;14:1062664
Frontiers in pharmacology 2023;14:1062664
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Guo Q, Xin M, Lu Q, Feng D, Yang V, Peng LF, Whelan KA, Hu W, Wu S, Yang X, Wang H, Rothberg BS, Gamero AM, Gerhard GS, Gao B, Yang L
Theranostics 2023;13(7):2210-2225
Theranostics 2023;13(7):2210-2225
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.
Li B, Xia Y, Mei S, Ye Z, Song B, Yan X, Lin F, Rao T, Yu W, Mei C, Lv J, Wu M, Mao Z, Zhou X, Cheng F
Theranostics 2023;13(6):1860-1875
Theranostics 2023;13(6):1860-1875
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.
Yu B, Jin L, Yao X, Zhang Y, Zhang G, Wang F, Su X, Fang Q, Xiao L, Yang Y, Jiang LH, Chen J, Yang W, Lin W, Han F
Theranostics 2023;13(13):4356-4375
Theranostics 2023;13(13):4356-4375
Ablation of NLRP3 inflammasome attenuates muscle atrophy via inhibiting pyroptosis, proteolysis and apoptosis following denervation.
You Z, Huang X, Xiang Y, Dai J, Xu L, Jiang J, Xu J
Theranostics 2023;13(1):374-390
Theranostics 2023;13(1):374-390
LTe2 induces cell apoptosis in multiple myeloma by suppressing AKT phosphorylation at Thr308 and Ser473.
Zhang Y, Qian J, Jiang M, Yang S, Zhou L, Zhang Q, Lin L, Yang Y
Frontiers in oncology 2023;13:1269670
Frontiers in oncology 2023;13:1269670
Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study.
Huang S, Qu M, Chen X, Yu S, Kong F
Frontiers in oncology 2023;13:1174848
Frontiers in oncology 2023;13:1174848
Missing link between tissue specific expressing pattern of ERβ and the clinical manifestations in LGBLEL.
Zhang X, Zhao P, Ma M, Wu H, Liu R, Liu Z, Cai Z, Liu M, Xie F, Ma X
Frontiers in medicine 2023;10:1168977
Frontiers in medicine 2023;10:1168977
Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy.
Yang M, Wang Z, Xie J, Reyad-Ul-Ferdous M, Li S, Song Y
Chronic diseases and translational medicine 2023 Sep;9(3):238-249
Chronic diseases and translational medicine 2023 Sep;9(3):238-249
Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation.
Zhang X, Chen J, Xi B, Liu Y, Wang S, Gu L, Zhao H, Tao L, Hua Y, Wang Y, Chen M
Phytotherapy research : PTR 2023 Sep;37(9):4076-4091
Phytotherapy research : PTR 2023 Sep;37(9):4076-4091
α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Zhang N, Zhang Y, Xu J, Wang P, Wu B, Lu S, Lu X, You S, Huang X, Li M, Zou Y, Liu M, Zhao Y, Sun G, Wang W, Geng D, Liu J, Cao L, Sun Y
Cell research 2023 Sep;33(9):679-698
Cell research 2023 Sep;33(9):679-698
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Li T, Tang Q, Xu J, Ye X, Chen K, Zhong J, Zhu J, Lu S, Zhu T
Stem cells and development 2023 Sep;32(17-18):539-553
Stem cells and development 2023 Sep;32(17-18):539-553
Pan-cancer integrated bioinformatic analysis of RNA polymerase subunits reveal RNA Pol I member CD3EAP regulates cell growth by modulating autophagy.
Bhandari N, Acharya D, Chatterjee A, Mandve L, Kumar P, Pratap S, Malakar P, Shukla SK
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):1986-2002
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):1986-2002
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Cui Y, Zhang W, Yang P, Zhu S, Luo S, Li M
Free radical biology & medicine 2023 Sep;206:33-49
Free radical biology & medicine 2023 Sep;206:33-49
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
Guo S, Chen J, Yang Y, Li X, Tang Y, Gui Y, Chen J, Xu J
Neurospine 2023 Sep;20(3):1011-1027
Neurospine 2023 Sep;20(3):1011-1027
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Chen ZL, Guo C, Zou YY, Feng C, Yang DX, Sun CC, Wen W, Jian ZJ, Zhao Z, Xiao Q, Zheng L, Peng XY, Zhou ZQ, Tang CF
Experimental gerontology 2023 Sep;180:112265
Experimental gerontology 2023 Sep;180:112265
Degradation of histone deacetylase 6 alleviates ROS-mediated apoptosis in renal ischemia-reperfusion injury.
Xia K, Qiu T, Jian Y, Liu H, Chen H, Liu X, Chen Z, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115128
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115128
Exploring the molecular mechanisms of the involvement of GZMB-Caspase-3-GSDME pathway in the progression of rheumatoid arthritis.
Zhang Y, Cai X, Wang B, Zhang B, Xu Y
Molecular immunology 2023 Sep;161:82-90
Molecular immunology 2023 Sep;161:82-90
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.
Zhang X, Shi L, Sun HD, Wang ZW, Xu F, Wei JF, Ding Q
Clinical and translational medicine 2023 Sep;13(9):e1427
Clinical and translational medicine 2023 Sep;13(9):e1427
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor.
Yang L, Liu T, Zhuo Y, Li D, Li D, Liu J, Gao H, Zhang L, Lin J, Wang X
Cellular signalling 2023 Sep;109:110768
Cellular signalling 2023 Sep;109:110768
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling.
Wang Z, Zhu D, Zhang Y, Xia F, Zhu J, Dai J, Zhuge X
Microbial cell factories 2023 Sep 9;22(1):177
Microbial cell factories 2023 Sep 9;22(1):177
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Xia B, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
European journal of pharmacology 2023 Sep 5;954:175864
European journal of pharmacology 2023 Sep 5;954:175864
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Chen J, Zheng D, Cai Z, Zhong B, Zhang H, Pan Z, Ling X, Han Y, Meng J, Li H, Chen X, Zhang H, Liu L
Toxics 2023 Sep 4;11(9)
Toxics 2023 Sep 4;11(9)
Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway.
Xie JR, Chen XJ, Zhou G
International journal of molecular sciences 2023 Sep 26;24(19)
International journal of molecular sciences 2023 Sep 26;24(19)
Oryza sativa L. Indica Seed Coat Ameliorated Concanavalin A-Induced Acute Hepatitis in Mice via MDM2/p53 and PKCα/MAPK1 Signaling Pathways.
Zhao Z, Li Y, Guo S, Chen Y, Yin H, Li Y, Cheng G, Tian L
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Zhou Q, Fang G, Pang Y, Wang X
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Yi L, Zhu S, Wu P, Zhang Y, Wang M, Xu P, Zeng J, Wang G, Luo L, Li W
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
Downregulation of lncRNA NEAT1 interacts with miR-374b-5p/PGAP1 axis to aggravate the development of osteoarthritis.
Huang F, Su Z, Yang J, Zhao X, Xu Y
Journal of orthopaedic surgery and research 2023 Sep 11;18(1):670
Journal of orthopaedic surgery and research 2023 Sep 11;18(1):670
Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease.
Almeida LM, Oliveira Â, Oliveira JMA, Pinho BR
Archives of biochemistry and biophysics 2023 Sep 1;745:109711
Archives of biochemistry and biophysics 2023 Sep 1;745:109711
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
Liu Z, Wang X, Li J, Yang X, Huang J, Ji C, Li X, Li L, Zhou J, Hu Y
Chemico-biological interactions 2023 Sep 1;382:110602
Chemico-biological interactions 2023 Sep 1;382:110602
In Silico Identification and Validation of Pyroptosis-Related Genes in Chlamydia Respiratory Infection.
Sun R, Zheng W, Yang S, Zeng J, Tuo Y, Tan L, Zhang H, Bai H
International journal of molecular sciences 2023 Sep 1;24(17)
International journal of molecular sciences 2023 Sep 1;24(17)
LncRNA AOC4P impacts the differentiation of macrophages and T-lymphocyte by regulating the NF-κB pathways of KGN cells: Potential pathogenesis of polycystic ovary syndrome.
Yang Z, Wu S, He S, Han L, Zhou M, Yang J, Chen J, Wu G
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Oct;90(4):e13776
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Oct;90(4):e13776
Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice.
Wang ZS, Shu B, Han Q, Li GH, Guo YL
International urology and nephrology 2023 Oct;55(10):2599-2610
International urology and nephrology 2023 Oct;55(10):2599-2610
The PRMT5 inhibitor C9 mitigates hypoxia-induced carboplatin resistance in lung cancer by inducing autophagy.
Fan J, Li H, Ruan Q, Zhu X, Jing P, Gu Z
Cell biology international 2023 Oct;47(10):1702-1715
Cell biology international 2023 Oct;47(10):1702-1715
Tenofovir disoproxil fumarate mediates neuronal injury by inducing neurotoxicity.
Yang X, Zhang J, Cheng Y, Cui M, Jiang Z, Fan C, Chen J, Qi L, Liu H, Bao D
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2023 Oct;42(10):1195-1205
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2023 Oct;42(10):1195-1205
Electroacupuncture inhibits hippocampal neuronal apoptosis and improves cognitive dysfunction in mice with vascular dementia via the JNK signaling pathway.
Liu Y, Yan Z, Ren Y, Wang W, Ke Y, Wang Y, Qi R
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2023 Oct;41(5):284-296
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2023 Oct;41(5):284-296
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.
Lin J, Zheng X, Xiong Z, Xiang Q, Zhao Y, Jiang S, Sun Z, Fan D, Sun C, Li W
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371
Effects of prenatal acetaminophen exposure at different stages, doses and courses on articular cartilage of offspring mice.
Zhang F, Liu L, Wang H, Chen L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114003
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114003
Kartogenin potentially protects temporomandibular joints from collagenase-induced osteoarthritis via core binding factor β and runt-related transcription factor 1 binding - A rat model study.
Ye L, Cao Z, Tan X, Zhao C, Cao Y, Pan J
Journal of dental sciences 2023 Oct;18(4):1553-1560
Journal of dental sciences 2023 Oct;18(4):1553-1560
Isoflurane-induced reduction in neurogenesis derived from the tertiary dentate matrix.
Xiao XL, Pan DM, Zhang ZQ, Wang T, Li DH, Zhang CT, Liu LF, Chen Y, Yang SN, Tan J, Fu GL, Ma YB, Wu XL, Zhou JS, Wu F, Si KW, Liu JX
Journal of chemical neuroanatomy 2023 Oct;132:102325
Journal of chemical neuroanatomy 2023 Oct;132:102325
Programmed Death Ligand-1-Overexpressing Donor Exosomes Mediate Donor-Specific Immunosuppression by Delivering Co-Inhibitory Signals to Donor-Specific T Cells.
Luo X, Du G, Long Y, Zheng M, Chen B, Li W, Yan G, Qi Z, Lan T
Advanced healthcare materials 2023 Oct;12(25):e2300670
Advanced healthcare materials 2023 Oct;12(25):e2300670
MiR-132-3p activation aggravates renal ischemia-reperfusion injury by targeting Sirt1/PGC1alpha axis.
Li C, Han S, Zhu J, Cheng F
Cellular signalling 2023 Oct;110:110801
Cellular signalling 2023 Oct;110:110801
TNFAIP3 interacting protein 2 relieves lipopolysaccharide (LPS)-induced inflammatory injury in endometritis by inhibiting NF-kappaB activation.
Qian X, Wang Y, Li X, Li Y, Li L
Immunity, inflammation and disease 2023 Oct;11(10):e970
Immunity, inflammation and disease 2023 Oct;11(10):e970
Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM leukemia cells.
Zhou M, Boulos JC, Omer EA, Rudbari HA, Schirmeister T, Micale N, Efferth T
European journal of pharmacology 2023 Oct 5;956:175980
European journal of pharmacology 2023 Oct 5;956:175980
Combined Epimedii Folium and Ligustri Lucidi Fructus with dexamethasone alleviate the proliferation of airway smooth muscle cells by regulating apoptosis/autophagy.
Long Y, Wang H, Ma Z, Li Y, Ma Z, Yu P, Tang X, Liu R
Journal of ethnopharmacology 2023 Oct 5;314:116547
Journal of ethnopharmacology 2023 Oct 5;314:116547
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of proliferation and apoptosis of smooth muscle cells in vitro and in vivo.
Xue Z, Zhou M, Liu Y, Qin H, Li Y, Zhu Y, Yang J
Journal of ethnopharmacology 2023 Oct 5;314:116544
Journal of ethnopharmacology 2023 Oct 5;314:116544
Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly(β-amino ester)s.
Zhao Y, Bo T, Wang C, Yao D, Pan C, Xu W, Zhou H, Li M, Zhang S
Journal of nanobiotechnology 2023 Oct 28;21(1):394
Journal of nanobiotechnology 2023 Oct 28;21(1):394
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
PABPN1 promotes clear cell renal cell carcinoma progression by suppressing the alternative polyadenylation of SGPL1 and CREG1.
Xiong M, Liu C, Li W, Jiang H, Long W, Zhou M, Yang C, Kazobinka G, Sun Y, Zhao J, Hou T
Carcinogenesis 2023 Oct 20;44(7):576-586
Carcinogenesis 2023 Oct 20;44(7):576-586
Insulin-induced gene 2 protects against hepatic ischemia-reperfusion injury via metabolic remodeling.
Wu Y, Li C, Khan AA, Chen K, Su R, Xu S, Sun Y, Gao F, Wang K, Wang X, Lian Z, Wang S, Yu M, Hu X, Yang F, Zheng S, Qiu N, Liu Z, Xu X
Journal of translational medicine 2023 Oct 19;21(1):739
Journal of translational medicine 2023 Oct 19;21(1):739
Melatonin-Mediated Suppression of mtROS-JNK-FOXO1 Pathway Alleviates Hypoxia-Induced Apoptosis in Porcine Granulosa Cells.
Zhang X, Zhang D, Li H, Liu Z, Yang Y, Li J, Tang L, Tao J, Liu H, Shen M
Antioxidants (Basel, Switzerland) 2023 Oct 19;12(10)
Antioxidants (Basel, Switzerland) 2023 Oct 19;12(10)
Neuronal RBM5 modulates cell signaling responses to traumatic and hypoxic-ischemic injury in a sex-dependent manner.
Snyder K, Gorse K, Kochanek PM, Jackson TC
Cell death discovery 2023 Oct 17;9(1):379
Cell death discovery 2023 Oct 17;9(1):379
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004
European journal of pharmacology 2023 Oct 15;957:176004
Dynamic changes of oligodendrogenesis in neonatal rats with hypoxic-ischemic white matter injury.
Lin Q, Lin L, Li L, Zheng YF, Hu DW, Zhang G
Brain research 2023 Oct 15;1817:148495
Brain research 2023 Oct 15;1817:148495
METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.
Yi J, Peng F, Zhao J, Gong X
Scientific reports 2023 Oct 12;13(1):17292
Scientific reports 2023 Oct 12;13(1):17292
Peptide Characterization of Bovine Myocardium Hydrolysates and Its Ameliorative Effects on Doxorubicin-Induced Myocardial Injury in H9c2 Cells and in Mice.
Li W, Lv M, Zhang T, Zhou M, Zheng L, Song T, Zhao M
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14562-14574
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14562-14574
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
Wang H, He D, Li Z, Gao X, Yang S, Cui M, Ye B, Huang B, Fu S, Liu D
Chemico-biological interactions 2023 Oct 1;384:110726
Chemico-biological interactions 2023 Oct 1;384:110726
Dapagliflozin suppress endoplasmic reticulum stress mediated apoptosis of chondrocytes by activating Sirt1.
Liu Z, Huang J, Wang X, Deng S, Zhou J, Gong Z, Li X, Wang Y, Yang J, Hu Y
Chemico-biological interactions 2023 Oct 1;384:110724
Chemico-biological interactions 2023 Oct 1;384:110724
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Zhang T, Bai J, Chen G, Chen Z, Zeng S, Yang Y, Wu Z
Chemico-biological interactions 2023 Oct 1;384:110695
Chemico-biological interactions 2023 Oct 1;384:110695
Chronic exposure to low-dose deltamethrin can lead to colon tissue injury through PRDX1 inactivation-induced mitochondrial oxidative stress injury and gut microbial dysbiosis.
Ma R, Sun T, Wang X, Ren K, Min T, Xie X, Wang D, Li K, Zhang Y, Zhu K, Mo C, Dang C, Yang Y, Zhang H
Ecotoxicology and environmental safety 2023 Oct 1;264:115475
Ecotoxicology and environmental safety 2023 Oct 1;264:115475
Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.
Zhuang S, Zhou X, Yang X, Chang D, Chen T, Sun Y, Wang C, Zhang C, Jiang J, Chen Y, Lin X, Wang X, Yu W, Lin X, He C, Zheng Y, Zhang J, Shi H
Heliyon 2023 Nov;9(11):e22007
Heliyon 2023 Nov;9(11):e22007
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Qiu K, Xia Q, Chen H, Ye Q, Mao H, Tian M, Gan Y, Huang Q, Wang H, Duan S
Heliyon 2023 Nov;9(11):e21851
Heliyon 2023 Nov;9(11):e21851
Effect of miR-182-5p on apoptosis in myocardial infarction.
Niu N, Miao H, Ren H
Heliyon 2023 Nov;9(11):e21524
Heliyon 2023 Nov;9(11):e21524
Protective effect and mechanism of procyanidin B2 against hypoxic injury of cardiomyocytes.
Xue Z, Wu D, Zhang J, Pan Y, Kan R, Gao J, Zhou B
Heliyon 2023 Nov;9(11):e21309
Heliyon 2023 Nov;9(11):e21309
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
Gong M, Jia J
Molecular neurobiology 2023 Nov;60(11):6598-6612
Molecular neurobiology 2023 Nov;60(11):6598-6612
The Extract of Pinellia Ternata-Induced Apoptosis of Leukemia Cells by Regulating the Expression of Bax, Bcl-2 and Caspase-3 Protein Expression in Mice.
Li ZF, Feng JK, Zhao XC, Liu W, Gu SA, Li R, Lu YL, Mao RJ, Xia LL, Dong LL, Zhang LW, Ruan JY, Liu J, Li GF, Li T, Sun R, Qiu SL, Zheng ZZ, Dong T
Transplantation proceedings 2023 Nov;55(9):2232-2240
Transplantation proceedings 2023 Nov;55(9):2232-2240
Pseudolaric acid B induces apoptosis associated with the mitochondrial and PI3K/AKT/mTOR pathways in triple‑negative breast cancer.
Yang K, Wang JQ, Li K, Chen SN, Yu F
Oncology reports 2023 Nov;50(5)
Oncology reports 2023 Nov;50(5)
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Hu H, Wang Y, Dong Y, Wang L, Chen Y, Zhou Y, Sun L
Molecular biology reports 2023 Nov;50(11):8985-8993
Molecular biology reports 2023 Nov;50(11):8985-8993
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.
Boulos JC, Omer EA, Rigano D, Formisano C, Chatterjee M, Leich E, Klauck SM, Shan LT, Efferth T
Acta pharmacologica Sinica 2023 Nov;44(11):2265-2281
Acta pharmacologica Sinica 2023 Nov;44(11):2265-2281
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
Luo H, Jiao QB, Shen CB, Gong WY, Yuan JH, Liu YY, Chen Z, Liu J, Xu XL, Cong YS, Zhang XW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221
Ginkgolide K delays the progression of osteoarthritis by regulating YAP to promote the formation of cartilage extracellular matrix.
Liu R, Liu Z, Chen H, He S, Wang S, Dai J, Li X
Phytotherapy research : PTR 2023 Nov;37(11):5205-5222
Phytotherapy research : PTR 2023 Nov;37(11):5205-5222
Tethering ATG16L1 or LC3 induces targeted autophagic degradation of protein aggregates and mitochondria.
Mei L, Chen X, Wei F, Huang X, Liu L, Yao J, Chen J, Luo X, Wang Z, Yang A
Autophagy 2023 Nov;19(11):2997-3013
Autophagy 2023 Nov;19(11):2997-3013
Escherichia coli infection mediates pyroptosis via activating p53-p21 pathway-regulated apoptosis and cell cycle arrest in bovine mammary epithelial cells.
Zhuang C, Zhao J, Zhang S, Shahid M
Microbial pathogenesis 2023 Nov;184:106338
Microbial pathogenesis 2023 Nov;184:106338
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
Shen G, Xiao H, Huang S, Yuan X, Rongrong Z, Ma Y, Qin X
Neurochemistry international 2023 Nov;170:105546
Neurochemistry international 2023 Nov;170:105546
The eNOS-induced leonurine's new role in improving the survival of random skin flap.
Chen T, Chen H, Fu Y, Liu X, Huang H, Li Z, Li S
International immunopharmacology 2023 Nov;124(Pt B):111037
International immunopharmacology 2023 Nov;124(Pt B):111037
A Dihydroartemisinin-Loaded Nanoreactor Motivates Anti-Cancer Immunotherapy by Synergy-Induced Ferroptosis to Activate Cgas/STING for Reprogramming of Macrophage.
Li LG, Yang XX, Xu HZ, Yu TT, Li QR, Hu J, Peng XC, Han N, Xu X, Chen NN, Chen X, Tang JM, Li TF
Advanced healthcare materials 2023 Nov;12(28):e2301561
Advanced healthcare materials 2023 Nov;12(28):e2301561
Targeting Esophageal Squamous Cell Carcinoma by Combining Copper Ionophore Disulfiram and JMJD3/UTX Inhibitor GSK J4.
Yang C, Li F, Ren Y, Zhang Q, Jiao B, Zhang J, Huang J
Cancers 2023 Nov 9;15(22)
Cancers 2023 Nov 9;15(22)
ADORA2A promotes proliferation and inhibits apoptosis through PI3K/AKT pathway activation in colorectal carcinoma.
Ran L, Mou X, Peng Z, Li X, Li M, Xu D, Yang Z, Sun X, Yin T
Scientific reports 2023 Nov 9;13(1):19477
Scientific reports 2023 Nov 9;13(1):19477
SOX4 as a potential therapeutic target for pathological cardiac hypertrophy.
Bin S, Xinyi F, Huan P, Xiaoqin Z, Jiming W, Yi H, Ziyue L, Xiaochun Z, Zhouqi L, Bangwei Z, Jing J, Shihui L, Jinlai G
European journal of pharmacology 2023 Nov 5;958:176071
European journal of pharmacology 2023 Nov 5;958:176071
MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer.
Wang C, Lin H, Zhao W, Liang Y, Chen Y, Wang C
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 30;69(12):232-241
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 30;69(12):232-241
Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation.
Iacono D, Murphy EK, Stimpson CD, Perl DP, Day RM
Scientific reports 2023 Nov 30;13(1):21142
Scientific reports 2023 Nov 30;13(1):21142
HDAC1-Mediated lncRNA Stimulatory Factor of Follicular Development to Inhibit the Apoptosis of Granulosa Cells and Regulate Sexual Maturity through miR-202-3p-COX1 Axis.
Zhou X, He Y, Quan H, Pan X, Zhou Y, Zhang Z, Yuan X, Li J
Cells 2023 Nov 29;12(23)
Cells 2023 Nov 29;12(23)
Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway.
Yao Z, Liu N, Lin H, Zhou Y
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1329-1340
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1329-1340
DJ1 Ameliorates AD-like Pathology in the Hippocampus of APP/PS1 Mice.
Peng YY, Li MX, Li WJ, Xue Y, Miao YF, Wang YL, Fan XC, Tang LL, Song HL, Zhang Q, Li X
Biomedical and environmental sciences : BES 2023 Nov 20;36(11):1028-1044
Biomedical and environmental sciences : BES 2023 Nov 20;36(11):1028-1044
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
Ma Q, Liu Z, Wang T, Zhao P, Liu M, Wang Y, Zhao W, Yuan Y, Li S
International journal of molecular sciences 2023 Nov 19;24(22)
International journal of molecular sciences 2023 Nov 19;24(22)
Syndecan-1 shedding destroys epithelial adherens junctions through STAT3 after renal ischemia/reperfusion injury.
Guo M, Shen D, Su Y, Xu J, Zhao S, Zhang W, Wang Y, Jiang W, Wang J, Geng X, Ding X, Xu X
iScience 2023 Nov 17;26(11):108211
iScience 2023 Nov 17;26(11):108211
Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway.
Cai T, Chen S, Wu C, Lou C, Wang W, Lin C, Jiang H, Xu X
BMC musculoskeletal disorders 2023 Nov 17;24(1):894
BMC musculoskeletal disorders 2023 Nov 17;24(1):894
Mechanism underlying the effect of Pulsatilla decoction in hepatocellular carcinoma treatment: a network pharmacology and in vitro analysis.
Liu K, Cao Z, Huang S, Kong F
BMC complementary medicine and therapies 2023 Nov 10;23(1):405
BMC complementary medicine and therapies 2023 Nov 10;23(1):405
LIMK1 m(6)A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.
Chen L, Sun K, Qin W, Huang B, Wu C, Chen J, Lai Q, Wang X, Zhou R, Li A, Liu S, Zhang Y
Cancer letters 2023 Nov 1;576:216420
Cancer letters 2023 Nov 1;576:216420
Effect of arsenic and copper in kidney of mice: Crosstalk between Nrf2/ Keap1 pathway in apoptosis and pyroptosis.
Li Y, Zhong G, He T, Quan J, Liu S, Liu Z, Tang Z, Yu W
Ecotoxicology and environmental safety 2023 Nov 1;266:115542
Ecotoxicology and environmental safety 2023 Nov 1;266:115542
Novel soybean polypeptide dglycin alleviates atherosclerosis in apolipoprotein E-deficient mice.
Zhao H, Dan P, Xi J, Chen Z, Zhang P, Wei W, Zhao Y
International journal of biological macromolecules 2023 Nov 1;251:126347
International journal of biological macromolecules 2023 Nov 1;251:126347
FGF21 protects against doxorubicin-induced cardiotoxicity by inhibiting connexin 43 ubiquitination.
Huang Y, Wei C, Li P, Shao Y, Wang M, Wang F, Niu G, Sun K, Zhang Q, Gou Z, Yan X
Free radical biology & medicine 2023 Nov 1;208:748-758
Free radical biology & medicine 2023 Nov 1;208:748-758
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Zhu Z, Li X, Wang X, Zuo X, Ma Y, Gao X, Liang Z, Zhang Z, Song Z, Ding T, Ju C, Li P, Li K, Zhang J, Quan H, Wang Z, Hu X
Bioengineering & translational medicine 2023 May;8(3):e10473
Bioengineering & translational medicine 2023 May;8(3):e10473
Inhibition of endogenous hydrogen sulfide production suppresses the growth of nasopharyngeal carcinoma cells.
Wang DY, Zhang J, Li HX, Zhang YX, Jing MR, Cai CB, Wang D, Qi HW, Wang YZ, Chen HJ, Li T, Zhai YK, Ji XY, Wu DD
Molecular carcinogenesis 2023 May;62(5):652-664
Molecular carcinogenesis 2023 May;62(5):652-664
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Wang S, Zhang X, Lei H, Song L, Huang Y, Kang T, Zhang M, Wang N, Yang P, Feng S, Wang J, Bai R, Wang N, Wang W, Zheng Y
Molecular carcinogenesis 2023 May;62(5):613-627
Molecular carcinogenesis 2023 May;62(5):613-627
Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.
Wang X, Yu S, Liu W, Lv P, Zhao L, Wang Y, Fu C, Meng L, Yang Q, Wang X, Huang Y, Zuo Z, Liu X
Acta diabetologica 2023 May;60(5):631-644
Acta diabetologica 2023 May;60(5):631-644
MicroRNA152-3p Protects Against Ischemia/Reperfusion-Induced Bbb Destruction Possibly Targeting the MAP3K2/JNK/c-Jun Pathway.
Li F, Zhou F, Yang B
Neurochemical research 2023 May;48(5):1293-1304
Neurochemical research 2023 May;48(5):1293-1304
IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis.
Dhamdhere MR, Gowda CP, Singh V, Liu Z, Carruthers N, Grant CN, Sharma A, Dovat S, Sundstrom JM, Wang HG, Spiegelman VS
Oncogene 2023 May;42(19):1558-1571
Oncogene 2023 May;42(19):1558-1571
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Yu Y, Xia LK, Di Y, Nie QZ, Chen XL
Neural regeneration research 2023 May;18(5):1132-1138
Neural regeneration research 2023 May;18(5):1132-1138
Environmental microcystin exposure triggers the poor prognosis of prostate cancer: Evidence from case-control, animal, and in vitro studies.
Pan C, Qin H, Yan M, Qiu X, Gong W, Luo W, Guo H, Han X
Journal of environmental sciences (China) 2023 May;127:69-81
Journal of environmental sciences (China) 2023 May;127:69-81
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
Dong Y, Han F, Su Y, Sun B, Zhao W, Pan C
International immunopharmacology 2023 May;118:110056
International immunopharmacology 2023 May;118:110056
p53 Activates the Lipoxygenase Activity of ALOX15B via Inhibiting SLC7A11 to Induce Ferroptosis in Bladder Cancer Cells.
Li X, Xiong W, Wang Y, Li Y, Cheng X, Liu W
Laboratory investigation; a journal of technical methods and pathology 2023 May;103(5):100058
Laboratory investigation; a journal of technical methods and pathology 2023 May;103(5):100058
Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis.
Yao Z, Qi W, Zhang H, Zhang Z, Liu L, Shao Y, Zeng H, Yin J, Pan H, Guo X, Liu A, Cai D, Bai X, Zhang H
eLife 2023 May 5;12
eLife 2023 May 5;12
Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus.
Song C, Zhao J, Hao J, Mi D, Zhang J, Liu Y, Wu S, Gao F, Jiang W
Cell death discovery 2023 May 4;9(1):144
Cell death discovery 2023 May 4;9(1):144
Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma.
Luo M, Huang M, Yang N, Zhu Y, Huang P, Xu Z, Wang W, Cai L
Bone research 2023 May 29;11(1):28
Bone research 2023 May 29;11(1):28
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Gong S, Zhu S, Zhou P, Cheng CY, Li W, Yao W, Sun F
ACS omega 2023 May 23;8(20):18245-18254
ACS omega 2023 May 23;8(20):18245-18254
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Zhang X, Wang S, Jin Y, Wang J, Wang R, Yang X, Zhang S, Yan T, Jia Y
Journal of ethnopharmacology 2023 May 23;308:116253
Journal of ethnopharmacology 2023 May 23;308:116253
Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD(+)/SIRT3 pathway.
Hao K, Chen F, Zhao L, Xu S, Xiong Y, Xu R, Xie X, Huang H, Shu C, Liu Z, Wang H, Wang G
Schizophrenia (Heidelberg, Germany) 2023 May 20;9(1):32
Schizophrenia (Heidelberg, Germany) 2023 May 20;9(1):32
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
Zhang Z, Guo L, Yang F, Peng S, Wang D, Lai X, Su B, Xie H
ACS chemical neuroscience 2023 May 17;14(10):1799-1809
ACS chemical neuroscience 2023 May 17;14(10):1799-1809
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway.
Zhang M, Bi X, Liu S, Liu Y, Wang Q
Toxicology 2023 May 15;490:153511
Toxicology 2023 May 15;490:153511
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
Zhang X, Gai X, Xu L, Ma W, Liu Q, Shi B, Fang C, Cai J, Zhang Z
Journal of Zhejiang University. Science. B 2023 May 15;24(5):406-417
Journal of Zhejiang University. Science. B 2023 May 15;24(5):406-417
USP11 exacerbates neuronal apoptosis after traumatic brain injury via PKM2-mediated PI3K/AKT signaling pathway.
Fang Y, Zhao T, Ni H, Li Y, Zhu Y, Gao R, Zhang L, Jia Z, Chen G
Brain research 2023 May 15;1807:148321
Brain research 2023 May 15;1807:148321
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Zhang Q, Yang X, Liu J, Song J, Zhang S, Chen L, Zhang M
Food & function 2023 May 11;14(9):4191-4203
Food & function 2023 May 11;14(9):4191-4203
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Yu X, Zhang Y, Pei K, Tan J, Tian H, Xu T, Liu F, Peng N, Huang Y, Huang X, Huang X, Wu J, Liu Q, Zeng L, Hua W, Huang X
Food & function 2023 May 11;14(9):4129-4142
Food & function 2023 May 11;14(9):4129-4142
UDP-glucuronate metabolism controls RIPK1-driven liver damage in nonalcoholic steatohepatitis.
Zhang T, Zhang N, Xing J, Zhang S, Chen Y, Xu D, Gu J
Nature communications 2023 May 11;14(1):2715
Nature communications 2023 May 11;14(1):2715
Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization.
Jiang X, Sun J, Guo S, Zhao Z, Chen Y, Cao J, Liu Y, Cheng G, Tian L, Li Y
Journal of ethnopharmacology 2023 May 10;307:116232
Journal of ethnopharmacology 2023 May 10;307:116232
Qingyihuaji Formula promotes apoptosis and autophagy through inhibition of MAPK/ERK and PI3K/Akt/mTOR signaling pathway on pancreatic cancer in vivo and in vitro.
Qian X, Bi QY, Wang ZN, Han F, Liu LM, Song LB, Li CY, Zhang AQ, Ji XM
Journal of ethnopharmacology 2023 May 10;307:116198
Journal of ethnopharmacology 2023 May 10;307:116198
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Xi T, Wang R, Pi D, Ouyang J, Yang J
Experimental cell research 2023 May 1;426(1):113556
Experimental cell research 2023 May 1;426(1):113556
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Zhong X, Li Z, Xu Q, Peng H, Su Y, Le K, Shu Z, Liao Y, Ma Z, Pan X, Xu S, Zhou S
Journal of hypertension 2023 May 1;41(5):775-793
Journal of hypertension 2023 May 1;41(5):775-793
Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21-5p/SOCS6 pathway.
Wang G, Shen X, Song X, Wang N, Wo X, Gao Y
Neurotoxicology 2023 Mar;95:12-22
Neurotoxicology 2023 Mar;95:12-22
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Wang Y, Yang X, Cao Y, Li X, Xu R, Yan J, Guo Z, Sun S, Sun X, Wu Y
Heliyon 2023 Mar;9(3):e14475
Heliyon 2023 Mar;9(3):e14475
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
Zhang L, Zhou T, Ji Q, He L, Lan Y, Ding L, Li L, Wang Z
Molecular biology reports 2023 Mar;50(3):2545-2557
Molecular biology reports 2023 Mar;50(3):2545-2557
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells.
Qu Y, Zong S, Wang Z, Du P, Wen Y, Li H, Wu N, Xiao H
Drug and chemical toxicology 2023 Mar;46(2):369-379
Drug and chemical toxicology 2023 Mar;46(2):369-379
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors.
Li WF, Alfason L, Huang C, Tang Y, Qiu L, Miyagishi M, Wu SR, Kasim V
Acta pharmacologica Sinica 2023 Mar;44(3):647-660
Acta pharmacologica Sinica 2023 Mar;44(3):647-660
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
Wang Y, Peng M, Zhong Y, Xiong W, Zhu L, Jin X
Oncogene 2023 Mar;42(13):952-966
Oncogene 2023 Mar;42(13):952-966
CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR-199b-5p and regulating STRN expression.
Liu J, Liu B
The Kaohsiung journal of medical sciences 2023 Mar;39(3):221-233
The Kaohsiung journal of medical sciences 2023 Mar;39(3):221-233
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
Chen Y, Liu Y, Jiang K, Wen Z, Cao X, Wu S
Journal of orthopaedic translation 2023 Mar;39:1-11
Journal of orthopaedic translation 2023 Mar;39:1-11
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
He X, Guo X, Deng B, Kang J, Liu W, Zhang G, Wang Y, Yang Y, Kang X
Experimental neurology 2023 Mar;361:114301
Experimental neurology 2023 Mar;361:114301
The combination of gemcitabine and ginsenoside Rh2 enhances the immune function of dendritic cells against pancreatic cancer via the CARD9-BCL10-MALT1 / NF-κB pathway.
Li Q, He J, Li S, Tian C, Yang J, Yuan H, Lu Y, Fagone P, Nicoletti F, Xiang M
Clinical immunology (Orlando, Fla.) 2023 Mar;248:109217
Clinical immunology (Orlando, Fla.) 2023 Mar;248:109217
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
Zhang L, Ma X, Shi R, Zhang L, Zhao R, Duan R, Qin Y, Gao S, Li X, Duan J, Li J
British journal of pharmacology 2023 Mar;180(5):628-646
British journal of pharmacology 2023 Mar;180(5):628-646
Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.
Lan XB, Ni YS, Liu N, Wei W, Liu Y, Yang JM, Ma L, Bai R, Zhang J, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114266
Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.
Jin J, Xu F, Zhang Y, Guan J, Fu J
Molecular immunology 2023 Mar;155:27-43
Molecular immunology 2023 Mar;155:27-43
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
Zhao J, Liu J, Liu S, Tian S, Yuan H, Li S
Epigenomics 2023 Mar;15(6):369-383
Epigenomics 2023 Mar;15(6):369-383
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Yang J, Chen X
Immunity, inflammation and disease 2023 Mar;11(3):e809
Immunity, inflammation and disease 2023 Mar;11(3):e809
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Zhang M, Li L, Li S, Liu Z, Zhang N, Sun B, Wang Z, Jia D, Liu M, Wang Q
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
Zhu Q, Luo Y, Wen Y, Wang D, Li J, Fan Z
Biochemical and biophysical research communications 2023 Mar 5;647:1-8
Biochemical and biophysical research communications 2023 Mar 5;647:1-8
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166
European journal of medicinal chemistry 2023 Mar 5;249:115166
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy.
Sun K, Guo Z, Zhang J, Hou L, Liang S, Lu F, Wang G, Xu J, Zhang X, Guo F, Zhu W
Cell death discovery 2023 Mar 31;9(1):109
Cell death discovery 2023 Mar 31;9(1):109
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease.
Guo Y, Wang M, Liu Y, Pang Y, Tian L, Zhao J, Liu M, Shen C, Meng Y, Wang Y, Cai Z, Zhao W
Chinese medicine 2023 Mar 26;18(1):32
Chinese medicine 2023 Mar 26;18(1):32
SDNOR, a Novel Antioxidative lncRNA, Is Essential for Maintaining the Normal State and Function of Porcine Follicular Granulosa Cells.
Huo Y, Li Q, Yang L, Li X, Sun C, Liu Y, Liu H, Pan Z, Li Q, Du X
Antioxidants (Basel, Switzerland) 2023 Mar 24;12(4)
Antioxidants (Basel, Switzerland) 2023 Mar 24;12(4)
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway.
Tian Y, Che H, Yang J, Jin Y, Yu H, Wang C, Fu Y, Li N, Zhang J
Toxins 2023 Mar 21;15(3)
Toxins 2023 Mar 21;15(3)
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Liu LL, Shannahan J, Zheng W
bioRxiv : the preprint server for biology 2023 Mar 18;
bioRxiv : the preprint server for biology 2023 Mar 18;
An integrated approach of network pharmacology, molecular docking, and experimental verification uncovers kaempferol as the effective modulator of HSD17B1 for treatment of endometrial cancer.
Ruan GY, Ye LX, Lin JS, Lin HY, Yu LR, Wang CY, Mao XD, Zhang SH, Sun PM
Journal of translational medicine 2023 Mar 17;21(1):204
Journal of translational medicine 2023 Mar 17;21(1):204
Exposure to bisphenol A alternatives bisphenol AF and fluorene-9-bisphenol induces gonadal injuries in male zebrafish.
Meng X, Su S, Wei X, Wang S, Guo T, Li J, Song H, Wang M, Wang Z
Ecotoxicology and environmental safety 2023 Mar 15;253:114634
Ecotoxicology and environmental safety 2023 Mar 15;253:114634
AAZ2 induces mitochondrial-dependent apoptosis by targeting PDK1 in gastric cancer.
Li Y, She W, Xu X, Liu Y, Wang X, Tian S, Li S, Wang M, Yu C, Liu P, Huang T, Wei Y
Journal of Zhejiang University. Science. B 2023 Mar 15;24(3):232-247
Journal of Zhejiang University. Science. B 2023 Mar 15;24(3):232-247
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Feng L, Luo G, Li Y, Zhang C, Liu Y, Liu Y, Chen H, He D, Zhu Y, Gan L
Veterinary research 2023 Mar 14;54(1):25
Veterinary research 2023 Mar 14;54(1):25
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Fang X, Zhang X, Zhang Y, Zhang X, Shan M, Guan S, Qiu Z, Zhu D, Luo H
Journal of ethnopharmacology 2023 Mar 1;303:115978
Journal of ethnopharmacology 2023 Mar 1;303:115978
Aidi injection enhances the anti-tumor impact of doxorubicin in H22 tumor-containing mice.
Lu Y, Zhang S, Zhu X, Wang K, He Y, Liu C, Sun J, Pan J, Zheng L, Liu W, Li Y, Huang Y, Liu T
Journal of ethnopharmacology 2023 Mar 1;303:115968
Journal of ethnopharmacology 2023 Mar 1;303:115968
Integrating metabolomics and network pharmacology to investigate Panax japonicus prevents kidney injury in HFD/STZ-induced diabetic mice.
Wang T, Huang X, Zhai K, Yu J, Li J, Duan H, Liu J, Lu Z, Guo J, Li F
Journal of ethnopharmacology 2023 Mar 1;303:115893
Journal of ethnopharmacology 2023 Mar 1;303:115893
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Liu X, Xi H, Han S, Zhang H, Hu J
Ecotoxicology and environmental safety 2023 Mar 1;252:114571
Ecotoxicology and environmental safety 2023 Mar 1;252:114571
Ursolic acid nanoparticles for glioblastoma therapy.
Li Y, Zhao L, Zhao Q, Zhou Y, Zhou L, Song P, Liu B, Chen Q, Deng G
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B.
Wang P, Liu D, Cui J, Yan S, Liang Y, Chen Q, Liu Y, Ren S, Chen P
Cutaneous and ocular toxicology 2023 Jun;42(2):74-81
Cutaneous and ocular toxicology 2023 Jun;42(2):74-81
Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.
Hui YJ, Chen H, Peng XC, Li LG, Di MJ, Liu H, Hu XH, Yang Y, Zhao KL, Li TF, Yu TT, Wang WX
Photodiagnosis and photodynamic therapy 2023 Jun;42:103558
Photodiagnosis and photodynamic therapy 2023 Jun;42:103558
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
Li Y, Wang D, Zhang Z, Wang Y, Zhang Z, Liang Z, Liu F, Chen L
Photodiagnosis and photodynamic therapy 2023 Jun;42:103342
Photodiagnosis and photodynamic therapy 2023 Jun;42:103342
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Wang Y, Guo Y, Liu H, Du X, Shi L, Wang W, Zhang S
Environmental toxicology 2023 Jun;38(6):1239-1250
Environmental toxicology 2023 Jun;38(6):1239-1250
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L
Cell death and differentiation 2023 Jun;30(6):1503-1516
Cell death and differentiation 2023 Jun;30(6):1503-1516
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma.
Fu Y, Liang X, Yang X, Liu J, Huang H, Zhang P, Li S, Zhu D, Zhang Y, Peng F, Chen Y, Chen Z
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100567
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100567
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Wang P, Zheng SY, Jiang RL, Wu HD, Li YA, Lu JL, Xiong Y, Han B, Lin L
Free radical biology & medicine 2023 Jun;202:76-96
Free radical biology & medicine 2023 Jun;202:76-96
Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.
Gu L, Jin X, Liang H, Yang C, Zhang Y
Pharmacological research 2023 Jun;192:106789
Pharmacological research 2023 Jun;192:106789
GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.
Lin A, Guo Y, Zhang H, Lin P, Tao K, Jiang L, Xu D, Chen B
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166687
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166687
Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy.
Xu XX, Shi RX, Fu Y, Wang JL, Tong X, Zhang SQ, Wang N, Li MX, Tong Y, Wang W, He M, Liu BY, Chen GL, Guo F
Neural regeneration research 2023 Jun;18(6):1277-1285
Neural regeneration research 2023 Jun;18(6):1277-1285
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis.
Dong F, Qu L, Duan Z, He Y, Ma X, Fan D
Bioorganic chemistry 2023 Jun;135:106537
Bioorganic chemistry 2023 Jun;135:106537
Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells.
Zhang C, Wang M, Ying Y, Meng F, Gao H, Zeng S, Zhu Y, Liu A, Zhang Z, Xu C
Cancer medicine 2023 Jun;12(11):12581-12592
Cancer medicine 2023 Jun;12(11):12581-12592
MicroRNA-324-3p inhibits osteosarcoma progression by suppressing PGAM1-mediated aerobic glycolysis.
Weng Y, Duan W, Yu X, Wu F, Yang D, Jiang Y, Wu J, Wang M, Wang X, Shen Y, Zhang Y, Xu H
Cancer science 2023 Jun;114(6):2345-2359
Cancer science 2023 Jun;114(6):2345-2359
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Chen J, Liu F, Wu J, Yang Y, He J, Wu F, Yang K, Li J, Jiang Z, Jiang Z
Cellular signalling 2023 Jun;106:110642
Cellular signalling 2023 Jun;106:110642
Potential Mechanisms of Metformin-Induced Apoptosis in HeLa Cells.
Chu Z, Tan Y, Xu C, Zhangsun D, Zhu X
Biomolecules 2023 Jun 6;13(6)
Biomolecules 2023 Jun 6;13(6)
Codelivery of TRAIL and Mitomycin C via Liposomes Shows Improved Antitumor Effect on TRAIL-Resistant Tumors.
Chang R, Fu R, Huang Y, Zhang J, Feng C, Wang R, Yan H, Li G, Chu X, Yuan F, Jia D, Li J
Molecular pharmaceutics 2023 Jun 5;20(6):2864-2875
Molecular pharmaceutics 2023 Jun 5;20(6):2864-2875
Alr Gene in Brucella suis S2: Its Role in Lipopolysaccharide Biosynthesis and Bacterial Virulence in RAW264.7.
Hao M, Wang M, Zhao D, Shi Y, Yuan Y, Li J, Zhai Y, Liu X, Zhou D, Chen H, Lin P, Tang K, Liu W, Jin Y, Wang A
International journal of molecular sciences 2023 Jun 28;24(13)
International journal of molecular sciences 2023 Jun 28;24(13)
The Natural Alkaloid (-)-N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex.
Feng L, Shang RR, Wang XJ, Li L, Li X, Gong YX, Shi LY, Wang JW, Qian ZY, Tan NH, Wang Z
Journal of natural products 2023 Jun 23;86(6):1449-1462
Journal of natural products 2023 Jun 23;86(6):1449-1462
Effect of Lactobacillus delbrueckii subsp. lactis on vaginal radiotherapy for gynecological cancer.
Bi Z, Wang Q, Yang T, Liu Y, Yuan J, Li L, Guo Y
Scientific reports 2023 Jun 21;13(1):10105
Scientific reports 2023 Jun 21;13(1):10105
DHCR24 reverses Alzheimer's disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xFAD mice.
Zhang WB, Huang Y, Guo XR, Zhang MQ, Yuan XS, Zu HB
Acta neuropathologica communications 2023 Jun 21;11(1):102
Acta neuropathologica communications 2023 Jun 21;11(1):102
[Cordycepin, a metabolite of Cordyceps militaris, inhibits xenograft tumor growth of tongue squamous cell carcinoma in nude mice].
Zheng Q, Shao Y, Zheng W, Zou Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):873-878
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):873-878
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Sun Y, Zhu L, Liu P, Zhang H, Guo F, Jin X
Cancer research 2023 Jun 15;83(12):2034-2051
Cancer research 2023 Jun 15;83(12):2034-2051
A multi-bioresponsive self-assembled nano drug delivery system based on hyaluronic acid and geraniol against liver cancer.
Duan S, Xia Y, Tian X, Cui J, Zhang X, Yang Q, Zhao T, Lin Y, Zhang F, Zhang X, Cen J
Carbohydrate polymers 2023 Jun 15;310:120695
Carbohydrate polymers 2023 Jun 15;310:120695
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Li XC, Wang S, Yang XX, Li TJ, Gu JX, Zhao L, Bao YR, Meng XS
Journal of ethnopharmacology 2023 Jun 12;309:116264
Journal of ethnopharmacology 2023 Jun 12;309:116264
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Blunting ROS/TRPML1 pathway protects AFB1-induced porcine intestinal epithelial cells apoptosis by restoring impaired autophagic flux.
Cheng X, Liang J, Wu D, Guo X, Cao H, Zhang C, Liu P, Hu R, Hu G, Zhuang Y
Ecotoxicology and environmental safety 2023 Jun 1;257:114942
Ecotoxicology and environmental safety 2023 Jun 1;257:114942
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Li H, Wei Y, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Hao J
Acta cardiologica 2023 Jul;78(5):594-606
Acta cardiologica 2023 Jul;78(5):594-606
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Ruan Z, Chi J, Kong Y, Li C, Ruan X, Zhou X, Chen Y, Li Y, Luo Z
Advanced biology 2023 Jul;7(7):e2200336
Advanced biology 2023 Jul;7(7):e2200336
Open hepatic artery flow with portal vein clamping protects against bile duct injury compared to pringles maneuver.
Zhang S, Cao P, Bi P, Yang F, Wu M, Luo D, Yang B
Scandinavian journal of gastroenterology 2023 Jul;58(7):771-781
Scandinavian journal of gastroenterology 2023 Jul;58(7):771-781
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Zheng Y, Sang M, Liu F, Gu L, Li J, Wu Y, Shan B
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Pseudolaric acid B triggers cell apoptosis by activating AMPK/JNK/DRP1/mitochondrial fission pathway in hepatocellular carcinoma.
Liu Z, Wang N, Meng Z, Lu S, Peng G
Toxicology 2023 Jul;493:153556
Toxicology 2023 Jul;493:153556
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Liang JP, He YM, Cui YL, Sun YN, He GS, Zhu ZG, Mao XL
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Liang C, Yi K, Zhou X, Li X, Zhong C, Cao H, Xie C, Zhu J
Phytotherapy research : PTR 2023 Jul;37(7):2995-3008
Phytotherapy research : PTR 2023 Jul;37(7):2995-3008
A mitochondria-targeting ROS-activated nanoprodrug for self-augmented antitumor oxidation therapy.
Zeng Z, Luo Y, Xu X, Shan T, Chen M, Huang Z, Huang Y, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2023 Jul;359:415-427
Journal of controlled release : official journal of the Controlled Release Society 2023 Jul;359:415-427
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Qi H, Liu T, Liu J, Teng Q, Ma Z, Wang S, Wen S, Zhang C, Ren X, Kong H, Kong L
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Silicate ions as soluble form of bioactive ceramics alleviate aortic aneurysm and dissection.
Que Y, Zhang Z, Zhang Y, Li X, Chen L, Chen P, Ou C, Yang C, Chang J
Bioactive materials 2023 Jul;25:716-731
Bioactive materials 2023 Jul;25:716-731
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Man J, Zhou W, Zuo S, Zhao X, Wang Q, Ma H, Li HY
Biochemical pharmacology 2023 Jul;213:115615
Biochemical pharmacology 2023 Jul;213:115615
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Hu M, Li T, Ma X, Liu S, Li C, Huang Z, Lin Y, Wu R, Wang S, Lu D, Lu T, Men X, Shen S, Huang H, Liu Y, Song K, Jian B, Jiang Y, Qiu W, Liu Q, Lu Z, Cai W
Nature communications 2023 Jul 4;14(1):3945
Nature communications 2023 Jul 4;14(1):3945
Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice.
Chen F, Zhan J, Al Mamun A, Tao Y, Huang S, Zhao J, Zhang Y, Xu Y, Du S, Lu W, Li X, Chen Z, Xiao J
Food & function 2023 Jul 31;14(15):7176-7194
Food & function 2023 Jul 31;14(15):7176-7194
TLR4 Overexpression Aggravates Bacterial Lipopolysaccharide-Induced Apoptosis via Excessive Autophagy and NF-κB/MAPK Signaling in Transgenic Mammal Models.
Wang S, Zhang K, Song X, Huang Q, Lin S, Deng S, Qi M, Yang Y, Lu Q, Zhao D, Meng F, Li J, Lian Z, Luo C, Yao Y
Cells 2023 Jul 3;12(13)
Cells 2023 Jul 3;12(13)
Foot-and-Mouth Disease Virus Induces Porcine Gasdermin E-Mediated Pyroptosis through the Protease Activity of 3C(pro).
Ren X, Yin M, Zhao Q, Zheng Z, Wang H, Lu Z, Li X, Qian P
Journal of virology 2023 Jul 27;97(7):e0068623
Journal of virology 2023 Jul 27;97(7):e0068623
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Li Y, Zhao R, Xiu Z, Yang X, Zhu Y, Han J, Li S, Li Y, Sun L, Li X, Jin N, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Zhang J, Meng X, Zhou Y, Jiang Z, Chen H, Meng Z, Zhang Q, Chen W
Cancer cell international 2023 Jul 19;23(1):142
Cancer cell international 2023 Jul 19;23(1):142
Inhibition of FEN1 promotes DNA damage and enhances chemotherapeutic response in prostate cancer cells.
Wang Z, Yong C, Fu Y, Sun Y, Guo Z, Liu SB, Hu Z
Medical oncology (Northwood, London, England) 2023 Jul 15;40(8):242
Medical oncology (Northwood, London, England) 2023 Jul 15;40(8):242
Hypothermic oxygenated perfusion attenuates DCD liver ischemia-reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum stress.
Yue P, Lv X, You J, Zou Y, Luo J, Lu Z, Cao H, Liu Z, Fan X, Ye Q
Cellular & molecular biology letters 2023 Jul 12;28(1):55
Cellular & molecular biology letters 2023 Jul 12;28(1):55
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma.
Chen X, Zhang L, Wang X, Xu L, Sun J, Liu Y, Liu X, Kalvakolanu DV, Guo B
Anti-cancer drugs 2023 Jul 1;34(6):715-724
Anti-cancer drugs 2023 Jul 1;34(6):715-724
Carnosic Acid Attenuates AβOs-Induced Apoptosis and Synaptic Impairment via Regulating NMDAR2B and Its Downstream Cascades in SH-SY5Y Cells.
Liu WY, Li Y, Li Y, Xu LZ, Jia JP
Molecular neurobiology 2023 Jan;60(1):133-144
Molecular neurobiology 2023 Jan;60(1):133-144
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Kong F, Zhang Y, Wang T, Zhong L, Feng C, Wu Y
The European journal of neuroscience 2023 Jan;57(2):217-232
The European journal of neuroscience 2023 Jan;57(2):217-232
TGF-β1 regulates the lncRNA transcriptome of ovarian granulosa cells in a transcription activity-dependent manner.
Li Q, Huo Y, Wang S, Yang L, Li Q, Du X
Cell proliferation 2023 Jan;56(1):e13336
Cell proliferation 2023 Jan;56(1):e13336
TNFα-induced IDH1 hyperacetylation reprograms redox homeostasis and promotes the chemotherapeutic sensitivity.
Yang H, Zhao X, Liu J, Jin M, Liu X, Yan J, Yao X, Mao X, Li N, Liang B, Xie W, Zhang K, Zhao J, Liu L, Huang G
Oncogene 2023 Jan;42(1):35-48
Oncogene 2023 Jan;42(1):35-48
Replication of standard bovine viral diarrhea strain OregonC24Va induces endoplasmic reticulum stress-mediated apoptosis of bovine trophoblast cells.
Yuan N, Song Q, Jin Y, Zhang Z, Wu Z, Sheng X, Qi X, Xing K, Xiao L, Wang X
Cell stress & chaperones 2023 Jan;28(1):49-60
Cell stress & chaperones 2023 Jan;28(1):49-60
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Ye Z, Xia Y, Li L, Li B, Chen W, Han S, Zhou X, Chen L, Yu W, Ruan Y, Cheng F
Translational oncology 2023 Jan;27:101578
Translational oncology 2023 Jan;27:101578
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
Chen Z, Wang Z, Liu D, Zhao X, Ning S, Liu X, Wang G, Zhang F, Luo F, Yao J, Tian X
Free radical biology & medicine 2023 Jan;194:62-70
Free radical biology & medicine 2023 Jan;194:62-70
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Tong F, Zhao JX, Fang ZY, Cui XT, Su DY, Liu X, Zhou JH, Wang GX, Qiu ZJ, Liu SZ, Fu JQ, Kang CS, Wang JC, Wang QX
Pharmacological research 2023 Jan;187:106606
Pharmacological research 2023 Jan;187:106606
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Liu C, Liu Z, Fang Y, Liao Z, Zhang Z, Yuan X, Yu T, Yang Y, Xiong M, Zhang X, Zhang G, Meng L, Zhang Z
Environment international 2023 Jan;171:107696
Environment international 2023 Jan;171:107696
Alternate-day fasting for the protection of cognitive impairment in c57BL/6J mice following whole-brain radiotherapy.
Wu Q, Yu M, Wang Z, Ai X, Liu Z, Zeng J, Li C, Yuan L, He J, Lin X, Wan W
Neurochemistry international 2023 Jan;162:105463
Neurochemistry international 2023 Jan;162:105463
CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway.
Wen C, Li Y, Huang Y, Wang N, He S, Bao M, Zhou H, Wu L
The international journal of biochemistry & cell biology 2023 Jan;154:106344
The international journal of biochemistry & cell biology 2023 Jan;154:106344
Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.
Sun T, Li J, Zeng C, Luo C, Luo X, Li H
Advanced healthcare materials 2023 Jan;12(2):e2202348
Advanced healthcare materials 2023 Jan;12(2):e2202348
Mechanism of action of Daqinjiao decoction in treating cerebral small vessel disease explored using network pharmacology and molecular docking technology.
Wang ZY, Li MZ, Li WJ, Ouyang JF, Gou XJ, Huang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154538
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154538
Double-modified oncolytic adenovirus armed with a recombinant interferon-like gene enhanced abscopal effects against malignant glioma.
Jiang S, Chai HH, Fang XL, Xu HS, Li TW, Tang QS, Gu JF, Zhang KJ, Liu XY, Shi ZF, Cao XP, Wu ZY, Zhou LF
Neuro-oncology advances 2023 Jan-Dec;5(1):vdad117
Neuro-oncology advances 2023 Jan-Dec;5(1):vdad117
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury.
Zhang Z, Pi R, Jiang Y, Ahmad M, Luo H, Luo J, Yang J, Sun B
Human & experimental toxicology 2023 Jan-Dec;42:9603271231172724
Human & experimental toxicology 2023 Jan-Dec;42:9603271231172724
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate.
Chen Y, Yang S, Liu L, Yang X, Duan Y, Zhang S, Han J
European journal of pharmacology 2023 Jan 5;938:175428
European journal of pharmacology 2023 Jan 5;938:175428
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Ding JF, Zhou Y, Xu SS, Shi KH, Sun H, Tu B, Song K, Xuan HY, Sha JM, Zhao JY, Tao H
European journal of pharmacology 2023 Jan 5;938:175398
European journal of pharmacology 2023 Jan 5;938:175398
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
Ma M, Luan X, Zheng H, Wang X, Wang S, Shen T, Ren D
International journal of molecular sciences 2023 Jan 5;24(2)
International journal of molecular sciences 2023 Jan 5;24(2)
Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds.
Sun R, Liu C, Liu J, Yin S, Song R, Ma J, Cao G, Lu Y, Zhang G, Wu Z, Chen A, Wang Y
Scientific reports 2023 Jan 4;13(1):132
Scientific reports 2023 Jan 4;13(1):132
5-Hydroxytryptophan inhibits β-casein biosynthesis and promotes goat mammary epithelial cell apoptosis through the JAK2/STAT5a axis and the HTR7.
Du W, Zhang ZF, Xiao JY, Wang Y, Liu WY, Zheng HL
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Lipopolysaccharide promotes apoptosis and oxidative injury of porcine small intestinal epithelial cells by down-regulating the expression of glutamine transporter ASCT2.
Tang X, Xiong K, Liu J, Li M
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Honokiol reduces cadmium-induced oxidative injury and endosomal/lysosomal vacuolation via protecting mitochondrial function in quail (Coturnix japonica) liver tissues.
Yuan J, Huang X, Gu J, Yuan Y, Liu Z, Zou H, Bian J
The Science of the total environment 2023 Jan 20;857(Pt 3):159626
The Science of the total environment 2023 Jan 20;857(Pt 3):159626
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
Yang C, Jin X, Liu X, Wu G, Yang W, Pang B, Jiang J, Liao D, Zhang Y
Cell death & disease 2023 Jan 20;14(1):47
Cell death & disease 2023 Jan 20;14(1):47
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Cheng B, Chu X, Liu R, Ma X, Wang M, Zhang J, Jiao P, Gao Q, Ma W, Zhang Y, Zhao C, Zhou D, Xiao S
Molecular pharmaceutics 2023 Jan 2;20(1):701-710
Molecular pharmaceutics 2023 Jan 2;20(1):701-710
Endosulfan induced kidney cell injury by modulating ACE2 through up-regulating miR-429 in HK-2 cells.
Zhang B, Liu S, Sun Y, Xu D
Toxicology 2023 Jan 15;484:153392
Toxicology 2023 Jan 15;484:153392
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z
Annals of translational medicine 2023 Jan 15;11(1):12
Annals of translational medicine 2023 Jan 15;11(1):12
METTL3 Regulates Osteoclast Biological Behaviors via iNOS/NO-Mediated Mitochondrial Dysfunction in Inflammatory Conditions.
Li D, He J, Fang C, Zhang Y, He M, Zhang Z, Hou J, Xu Q
International journal of molecular sciences 2023 Jan 11;24(2)
International journal of molecular sciences 2023 Jan 11;24(2)
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Xing F, Gao H, Chen G, Sun L, Sun J, Qiao X, Xue J, Liu C
Molecular cancer 2023 Jan 10;22(1):6
Molecular cancer 2023 Jan 10;22(1):6
Intravenous Transplantation of an Ischemic-specific Peptide-TPP-mitochondrial Compound Alleviates Myocardial Ischemic Reperfusion Injury.
Sun X, Chen H, Gao R, Qu Y, Huang Y, Zhang N, Hu S, Fan F, Zou Y, Hu K, Chen Z, Ge J, Sun A
ACS nano 2023 Jan 10;17(2):896-909
ACS nano 2023 Jan 10;17(2):896-909
Aluminum exposure induces nephrotoxicity via fibrosis and apoptosis through the TGF-β1/Smads pathway in vivo and in vitro.
Wei H, Li D, Luo Y, Wang Y, Lin E, Wei X
Ecotoxicology and environmental safety 2023 Jan 1;249:114422
Ecotoxicology and environmental safety 2023 Jan 1;249:114422
Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.
Huang J, Zou L, Bao M, Feng Q, Xia W, Zhu C
Ecotoxicology and environmental safety 2023 Jan 1;249:114371
Ecotoxicology and environmental safety 2023 Jan 1;249:114371
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Xi H, Hu Z, Han S, Liu X, Wang L, Hu J
Theriogenology 2023 Jan 1;195:103-114
Theriogenology 2023 Jan 1;195:103-114
An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer's disease rat model.
Zhao JK, Hou SJ, Zhao JW, Yu HL, Duan SR
Translational neuroscience 2023 Jan 1;14(1):20220298
Translational neuroscience 2023 Jan 1;14(1):20220298
Interleukin-32γ promotes macrophage-mediated chemoresistance by inducing CSF1-dependent M2 macrophage polarization in multiple myeloma.
Yan H, He D, Qu J, Liu Y, Xu R, Gu H, Chen J, Li Y, Zhang E, Zhao Y, He J, Cai Z
Cancer immunology, immunotherapy : CII 2023 Feb;72(2):327-338
Cancer immunology, immunotherapy : CII 2023 Feb;72(2):327-338
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Yang J, Han F, Wu G, Dong Y, Su H, Xu J, Li J
Digestive diseases and sciences 2023 Feb;68(2):478-486
Digestive diseases and sciences 2023 Feb;68(2):478-486
SIRT7 silencing by miR-152-3p confers cell apoptosis and renal functional impairment induced by renal ischaemia/reperfusion injury.
Wang Y, Wu XQ, Cai JR, Ji HX, Xu T
International urology and nephrology 2023 Feb;55(2):367-376
International urology and nephrology 2023 Feb;55(2):367-376
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Yang W, Jia C, Liu L, Fu Y, Wu Y, Liu Z, Yu R, Ma X, Gong A, Liu F, Xia Y, Hou Y, Li Y, Zhang L
Inflammation 2023 Feb;46(1):270-284
Inflammation 2023 Feb;46(1):270-284
TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex.
Wang Y, Yao Y, Wei Q, Long S, Chen Y, Xie J, Tan R, Jiang W, Zhang Q, Wu D, Xiao S, Wan F, Fu K
Oncogene 2023 Feb;42(8):586-600
Oncogene 2023 Feb;42(8):586-600
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Fang Q, Zheng S, Chen Q, Chen L, Yang Y, Wang Y, Zhang H, Chen J
Metabolic brain disease 2023 Feb;38(2):453-466
Metabolic brain disease 2023 Feb;38(2):453-466
Curcumin alleviates ketamine-induced oxidative stress and apoptosis via Nrf2 signaling pathway in rats' cerebral cortex and hippocampus.
Zhang X, Cui Y, Song X, Jin X, Sheng X, Xu X, Li T, Chen H, Gao L
Environmental toxicology 2023 Feb;38(2):300-311
Environmental toxicology 2023 Feb;38(2):300-311
Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma.
Zhu XF, Sun ZL, Ma J, Hu B, Yu MC, Liu XJ, Yang P, Xu Y, Ju D, Mu Q
Phytotherapy research : PTR 2023 Feb;37(2):592-610
Phytotherapy research : PTR 2023 Feb;37(2):592-610
Berberine promotes the viability of random skin flaps via the PI3K/Akt/eNOS signaling pathway.
Chen J, Jiang Z, Liu X, Wang K, Fan W, Chen T, Li Z, Lin D
Phytotherapy research : PTR 2023 Feb;37(2):424-437
Phytotherapy research : PTR 2023 Feb;37(2):424-437
DNMT1-mediated lncRNA IFFD controls the follicular development via targeting GLI1 by sponging miR-370.
Zhou X, He Y, Pan X, Quan H, He B, Li Y, Bai G, Li N, Zhang Z, Zhang H, Li J, Yuan X
Cell death and differentiation 2023 Feb;30(2):576-588
Cell death and differentiation 2023 Feb;30(2):576-588
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Jiang B, Feng L, Yang T, Guo W, Li Y, Wang T, Liu C, Su H
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
Bao Y, Li X, El-Samahy MA, Yang H, Wang Z, Yang F, Yao X, Wang F
Theriogenology 2023 Feb;197:198-208
Theriogenology 2023 Feb;197:198-208
A plant nonenveloped double-stranded RNA virus activates and co-opts BNIP3-mediated mitophagy to promote persistent infection in its insect vector.
Liang Q, Wan J, Liu H, Jia D, Chen Q, Wang A, Wei T
Autophagy 2023 Feb;19(2):616-631
Autophagy 2023 Feb;19(2):616-631
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons.
Yan WT, Zhao WJ, Hu XM, Ban XX, Ning WY, Wan H, Zhang Q, Xiong K
Neural regeneration research 2023 Feb;18(2):357-363
Neural regeneration research 2023 Feb;18(2):357-363
Decreased expression and DNA hypermethylation of syncytin-1 in human villus tissues with unexplained recurrent spontaneous abortion.
Fu Y, Song Y, Zhang J, Wei LP, Sun XR
Journal of reproductive immunology 2023 Feb;155:103784
Journal of reproductive immunology 2023 Feb;155:103784
Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.
Shen C, Yue X, Dai L, Wang J, Li J, Fang Q, Zhi Y, Shi C, Li W
Journal of cancer research and clinical oncology 2023 Feb;149(2):683-699
Journal of cancer research and clinical oncology 2023 Feb;149(2):683-699
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Jiang X, Lu Z, Zhang Q, Yu J, Han D, Liu J, Li P, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
Li T, Bai H, Yang L, Hao W, Wei S, Yan P
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2023 Feb-Mar;264:110813
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2023 Feb-Mar;264:110813
Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats.
Otsuka S, Itashiki Y, Tani A, Matsuoka T, Takada S, Matsuzaki R, Nakanishi K, Norimatsu K, Tachibe Y, Kitazato R, Nojima N, Kakimoto S, Kikuchi K, Maruyama I, Sakakima H
Scientific reports 2023 Feb 7;13(1):2158
Scientific reports 2023 Feb 7;13(1):2158
Spleen Toxicity of Organophosphorus Flame Retardant TDCPP in Mice and the Related Mechanisms.
Cao L, Wei L, Du Q, Su Y, Ye S, Liu K
Toxics 2023 Feb 27;11(3)
Toxics 2023 Feb 27;11(3)
The protective effect of the mitochondrial-derived peptide MOTS-c on LPS-induced septic cardiomyopathy.
Wu J, Xiao D, Yu K, Shalamu K, He B, Zhang M
Acta biochimica et biophysica Sinica 2023 Feb 25;55(2):285-294
Acta biochimica et biophysica Sinica 2023 Feb 25;55(2):285-294
Combined use of dasatinib and quercetin alleviates overtraining-induced deficits in learning and memory through eliminating senescent cells and reducing apoptotic cells in rat hippocampus.
Wang C, Kang Y, Liu P, Liu W, Chen W, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Behavioural brain research 2023 Feb 25;440:114260
Behavioural brain research 2023 Feb 25;440:114260
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Wu J, Lin S, Chen W, Lian G, Wu W, Chen A, Sagor MIH, Luo L, Wang H, Xie L
Cell death discovery 2023 Feb 24;9(1):76
Cell death discovery 2023 Feb 24;9(1):76
Salidroside Alleviates Diabetic Cognitive Dysfunction Via B3galt2/F3/Contactin Signaling Pathway in Mice.
Lv P, Zuo Z, Liu W, Zhao L, Wang Y, Wang X, Yu S, Yu H, Zhang T, Bi J, Liu X
Neuroscience 2023 Feb 21;512:47-58
Neuroscience 2023 Feb 21;512:47-58
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z, Fan M, Hou J, Pan S, Xu Y, Zhang H, Liu C, Hao X, Li X, Wang H
Cell death & disease 2023 Feb 20;14(2):144
Cell death & disease 2023 Feb 20;14(2):144
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Deng L, Yang L, Zhu S, Li M, Wang Y, Cao X, Wang Q, Guo L
Cell death discovery 2023 Feb 2;9(1):40
Cell death discovery 2023 Feb 2;9(1):40
Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice.
McGehee OC, Ebrahim HY, Rad AH, Abdelwahed KS, Mudhish EA, King JA, Helal IE, Meyer SA, El Sayed KA
Molecules (Basel, Switzerland) 2023 Feb 2;28(3)
Molecules (Basel, Switzerland) 2023 Feb 2;28(3)
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, Chen J, Sun Z, He P
Experimental cell research 2023 Feb 15;423(2):113469
Experimental cell research 2023 Feb 15;423(2):113469
m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: Novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells.
Fu H, Zhu X, Di Q, Sun J, Jiang Q, Xu Q
The Science of the total environment 2023 Feb 10;859(Pt 2):160432
The Science of the total environment 2023 Feb 10;859(Pt 2):160432
MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells.
Hu Z, Linn N, Li Q, Zhang K, Liao J, Han Q, Zhang H, Guo J, Hu L, Pan J, Li Y, Tang Z
The Science of the total environment 2023 Feb 1;858(Pt 3):160157
The Science of the total environment 2023 Feb 1;858(Pt 3):160157
YM155 inhibits neuroblastoma growth through degradation of MYCN: A new role as a USP7 inhibitor.
Li X, Yang F, He N, Zhang M, Lv Y, Yu Y, Dong Q, Hou X, Hao Y, An Z, Zhang H, Yang Z, Zhai H, Guo D, Cao Z, Jiang VC, Chen Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Feb 1;181:106343
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Feb 1;181:106343
TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin‒proteasome-mediated degradation of PRKCD.
Sun L, Chen Y, Xia L, Wang J, Zhu J, Li J, Wang K, Shen K, Zhang D, Zhang G, Shi T, Chen W
Oncogene 2023 Dec;42(49):3619-3632
Oncogene 2023 Dec;42(49):3619-3632
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells.
Zhou M, Boulos JC, Klauck SM, Efferth T
Cell biology and toxicology 2023 Dec;39(6):2971-2997
Cell biology and toxicology 2023 Dec;39(6):2971-2997
Uqcr11 alleviates oxidative stress and apoptosis after traumatic brain injury.
Lin Y, Zhang J, Lu D, Zhang Y, Xu J, Wang S, Cheng X, Qin J, Zhang L, Li H, Zhang X, Li W
Experimental neurology 2023 Dec;370:114582
Experimental neurology 2023 Dec;370:114582
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis.
Tang L, Zhang D, Zhang Y, Peng Y, Li M, Song H, Chen H, Li W, Li X
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1618-1627
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1618-1627
Cold Stress Induces Apoptosis in Silver Pomfret via DUSP-JNK Pathway.
Hu J, Zhang M, Yan K, Zhang Y, Li Y, Zhu J, Wang G, Wang X, Li Y, Huang X, Tang J, Zheng R, Xu S, Wang D, Wang Y, Yan X
Marine biotechnology (New York, N.Y.) 2023 Dec;25(6):846-857
Marine biotechnology (New York, N.Y.) 2023 Dec;25(6):846-857
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Wang Y, Zhao Y, Ling Z, Luan D, Kang J, Dong X, Quan F
Theriogenology 2023 Dec;212:91-103
Theriogenology 2023 Dec;212:91-103
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Xu Q, Cao Y, Zhong X, Qin X, Feng J, Peng H, Su Y, Ma Z, Zhou S
British journal of pharmacology 2023 Dec;180(23):3024-3044
British journal of pharmacology 2023 Dec;180(23):3024-3044
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Yan J, Xie J, Xu S, Guo Y, Ji K, Li C, Gao H, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Lu D, Liu Y, Huang H, Hu M, Li T, Wang S, Shen S, Wu R, Cai W, Lu T, Lu Z
Translational stroke research 2023 Dec;14(6):910-928
Translational stroke research 2023 Dec;14(6):910-928
Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion.
Wu YF, Sun J, Chen M, Lin Q, Jin KY, Su SH, Hai J
International immunopharmacology 2023 Dec;125(Pt A):111108
International immunopharmacology 2023 Dec;125(Pt A):111108
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Identification of a Difluorinated Alkoxy Sulfonyl Chloride as a Novel Antitumor Agent for Hepatocellular Carcinoma through Activating Fumarate Hydratase Activity.
Jin J, Liang X, Bi W, Liu R, Zhang S, He Y, Xie Q, Liu S, Xiao JC, Zhang P
Pharmaceuticals (Basel, Switzerland) 2023 Dec 8;16(12)
Pharmaceuticals (Basel, Switzerland) 2023 Dec 8;16(12)
Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.
Yi Y, Tianxin Y, Zhangchi L, Cui Z, Weiguo W, Bo Y
European journal of pharmacology 2023 Dec 5;960:176169
European journal of pharmacology 2023 Dec 5;960:176169
Cynanchum komarovii extract for the treatment of rheumatoid arthritis by acting on synovial cells in vitro and in vivo.
Hao F, Tao L, Liu J, Ma Y, Zhang J, Wang W, Yan W, Wang B, Wang X, Chen X, Ma Y, Fan H, Zhao X, Wang Z, Bai C
Journal of ethnopharmacology 2023 Dec 5;317:116825
Journal of ethnopharmacology 2023 Dec 5;317:116825
hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
Xu L, Ma X, Zhang X, Zhang C, Zhang Y, Gong S, Wu N, Zhang P, Feng X, Guo J, Zhao M, Ren Z, Zhang P
Molecular cancer 2023 Dec 4;22(1):195
Molecular cancer 2023 Dec 4;22(1):195
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Chen Y, Yin H, Sun J, Zhang G, Zhang Y, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Mesenchymal stem cell exosomes inhibit nucleus pulposus cell apoptosis via the miR-125b-5p/TRAF6/NF-κB pathway axis.
Duan Y, Yu C, Kuang W, Li J, Qiu S, Ni S, Chen Z
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1938-1949
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1938-1949
PD-L1 and AKT Overexpressing Adipose-Derived Mesenchymal Stem Cells Enhance Myocardial Protection by Upregulating CD25(+) T Cells in Acute Myocardial Infarction Rat Model.
Lin YK, Hsiao LC, Wu MY, Chen YF, Lin YN, Chang CM, Chung WH, Chen KW, Lu CR, Chen WY, Chang SS, Shyu WC, Lee AS, Chen CH, Jeng LB, Chang KC
International journal of molecular sciences 2023 Dec 21;25(1)
International journal of molecular sciences 2023 Dec 21;25(1)
Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression.
Cong L, Liu X, Bai Y, Qin Q, Zhao L, Shi Y, Bai Y, Guo Z
Biological research 2023 Dec 2;56(1):62
Biological research 2023 Dec 2;56(1):62
Cryptocaryone induces apoptosis in human hepatocellular carcinoma cells by inhibiting aerobic glycolysis through Akt and c-Src signaling pathways.
Yu CL, Lai YW, Chen JJ, Lee JJ, Chou TH, Huang CC, Liu SC, Chen GW, Tsai CH, Wang SW
Journal of food and drug analysis 2023 Dec 15;31(4):696-710
Journal of food and drug analysis 2023 Dec 15;31(4):696-710
Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis.
Liu J, Sun Y, Chen W, Deng L, Chen M, Dong J
BMC complementary medicine and therapies 2023 Dec 15;23(1):461
BMC complementary medicine and therapies 2023 Dec 15;23(1):461
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
Xie F, Qu J, Lin D, Feng K, Tan M, Liao H, Zeng L, Xiong Q, Huang J, Chen W
Molecular biology reports 2023 Dec 12;51(1):10
Molecular biology reports 2023 Dec 12;51(1):10
PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer.
Wang C, Xu YH, Xu HZ, Li K, Zhang Q, Shi L, Zhao L, Chen X
Journal of nanobiotechnology 2023 Dec 11;21(1):476
Journal of nanobiotechnology 2023 Dec 11;21(1):476
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Yang R, Wan J, Ma L, Zhou F, Yang Z, Li Z, Zhang M, Ming L
Cell death discovery 2023 Dec 1;9(1):431
Cell death discovery 2023 Dec 1;9(1):431
Mouth breathing induces condylar remodelling and chondrocyte apoptosis via both the extrinsic and mitochondrial pathways in male adolescent rats.
Wang Y, Liu Z, Ma G, Xu Y, Li Y
Tissue & cell 2023 Aug;83:102146
Tissue & cell 2023 Aug;83:102146
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
He Y, Zhang B, Han D, Du Y, Zhang X, Wang H, Yue Z, Shang P
Biochemical genetics 2023 Aug;61(4):1265-1281
Biochemical genetics 2023 Aug;61(4):1265-1281
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Hu Z, Zhang Y, Chen J, Luo M, Wang N, Xiao Y, He Q
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.
Yao H, Zhang S, Xie H, Fan Y, Miao M, Zhu R, Yuan L, Gu M, You Y, You B
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048
Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS-mediated mitochondrial pathway.
Chen Y, Zhang Y, Wang X, Qiao S
Journal of biochemical and molecular toxicology 2023 Aug;37(8):e23387
Journal of biochemical and molecular toxicology 2023 Aug;37(8):e23387
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Gu L, Wang F, Wang Y, Sun D, Sun Y, Tian T, Meng Q, Yin L, Xu L, Lu X, Peng J, Lin Y, Sun P
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
He P, He Y, Ma J, Liu Y, Liu C, Baoping Y, Dong W
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
Hao Z, Yuan Q, Tang H, Lei C, Chen Y, Su H, Zhang C
The FEBS journal 2023 Aug;290(15):3858-3876
The FEBS journal 2023 Aug;290(15):3858-3876
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Wang X, Zhou Y, Sun Q, Zhang Q, Zhou H, Zhang J, Du Y, Wang Y, Yuan K, Xu L, Zhang M, Yan D, Zeng L, Xu K, Sang W
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Role of Autophagy and Apoptosis in Aluminum Exposure-Induced Liver Injury in Rats.
Wei X, Li D, Luo Y, Wu B
Biological trace element research 2023 Aug;201(8):3971-3980
Biological trace element research 2023 Aug;201(8):3971-3980
Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy.
Zhang J, Tang Y, Xu W, Hu Z, Xu S, Niu Q
Biological trace element research 2023 Aug;201(8):3850-3860
Biological trace element research 2023 Aug;201(8):3850-3860
N-Acetylserotonin Protects Rat Nucleus Pulposus Cells Against Oxidative Stress Injury by Activating the PI3K/AKT Signaling Pathway.
Yidian W, Jihe K, Xudong G, Daxue Z, Mingqiang L, Xuewen K
World neurosurgery 2023 Aug;176:e109-e124
World neurosurgery 2023 Aug;176:e109-e124
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Feng DD, Chen JH, Chen YF, Cao Q, Li BJ, Chen XQ, Jin R, Zhou GP
Molecular immunology 2023 Aug;160:67-79
Molecular immunology 2023 Aug;160:67-79
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
Cui J, Xu T, Lv H, Guo MY
Fish & shellfish immunology 2023 Aug;139:108905
Fish & shellfish immunology 2023 Aug;139:108905
SIRT6 deficiency in endothelial cells exacerbates oxidative stress by enhancing HIF1α accumulation and H3K9 acetylation at the Ero1α promoter.
Guo Z, Yu X, Zhao S, Zhong X, Huang D, Feng R, Li P, Fang Z, Hu Y, Zhang Z, Abdurahman M, Huang L, Zhao Y, Wang X, Ge J, Li H
Clinical and translational medicine 2023 Aug;13(8):e1377
Clinical and translational medicine 2023 Aug;13(8):e1377
Multi-Catcher Polymers Regulate the Nucleolin Cluster on the Cell Surface for Cancer Therapy.
Cheng F, Jiang Y, Kong B, Lin H, Shuai X, Hu P, Gao P, Zhan L, Huang C, Li C
Advanced healthcare materials 2023 Aug;12(21):e2300102
Advanced healthcare materials 2023 Aug;12(21):e2300102
The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.
Zhang X, Xiao Y, Huang Q
International journal of biological macromolecules 2023 Aug 30;247:125747
International journal of biological macromolecules 2023 Aug 30;247:125747
Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.
Wang J, Ji Y, Ai C, Chen JR, Gan D, Zhang J, Mo JQ, Guan MX
Journal of biomedical science 2023 Aug 3;30(1):63
Journal of biomedical science 2023 Aug 3;30(1):63
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Gao Z, Zhan H, Zong W, Sun M, Linghu L, Wang G, Meng F, Chen M
Life sciences 2023 Aug 15;327:121793
Life sciences 2023 Aug 15;327:121793
Trimetazidine Affects Mitochondrial Calcium Uniporter Expression to Restore Ischemic Heart Function via Reactive Oxygen Species/NFκB Pathway Inhibition.
Xiao Z, Guan L, Shi H, Yu Y, Yu Z, Qin S, Su Y, Chen R, Li M, Ge J
Journal of cardiovascular pharmacology 2023 Aug 1;82(2):104-116
Journal of cardiovascular pharmacology 2023 Aug 1;82(2):104-116
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Zheng Y, Zhan Y, Zhang Y, Zhang Y, Liu Y, Xie Y, Sun Y, Qian J, Ding Y, Ding Y, Fang Y
Cell death & disease 2023 Aug 1;14(8):488
Cell death & disease 2023 Aug 1;14(8):488
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro.
Du P, Liu T, Luo P, Li H, Tang W, Zong S, Xiao H
Archives of toxicology 2023 Apr;97(4):1147-1162
Archives of toxicology 2023 Apr;97(4):1147-1162
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
Chang T, Lian Z, Ma S, Liang Z, Ma X, Wen X, Wang Y, Liu R
The Prostate 2023 Apr;83(5):470-486
The Prostate 2023 Apr;83(5):470-486
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X
Redox biology 2023 Apr;60:102618
Redox biology 2023 Apr;60:102618
Decreased autophagic activity of detrusor cells is involved in the inflammatory response of interstitial cystitis/bladder pain syndrome.
Zhao J, Lu Q, Yang Z, Sun B, Zhu J, Zhang H, Yang C, Yi S, Dong X
International urogynecology journal 2023 Apr;34(4):843-851
International urogynecology journal 2023 Apr;34(4):843-851
IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway.
Gao J, Suo S, Li J, Wang C, Deng R, Hu Y, Zhang C
Experimental and therapeutic medicine 2023 Apr;25(4):169
Experimental and therapeutic medicine 2023 Apr;25(4):169
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
Zhang RL, Lei BX, Wu GY, Wang YY, Huang QH
Bioorganic chemistry 2023 Apr;133:106210
Bioorganic chemistry 2023 Apr;133:106210
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Zheng G, Su Y, Wei L, Yao Y, Wang Y, Luo X, Wang X, Ruan XZ, Li D, Chen Y
Cell death & disease 2023 Apr 6;14(4):249
Cell death & disease 2023 Apr 6;14(4):249
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.
Lai F, Wang H, Zhao X, Yang K, Cai L, Hu M, Lin L, Xia X, Li W, Cheng H, Zhou R
Cell & bioscience 2023 Apr 6;13(1):71
Cell & bioscience 2023 Apr 6;13(1):71
Structure-based discovery of novel α-aminoketone derivatives as dual p53-MDM2/MDMX inhibitors for the treatment of cancer.
Luo HJ, Si DJ, Sun XJ, Wang MY, Yang YB, Wang B, Wen HM, Li W, Liu J
European journal of medicinal chemistry 2023 Apr 5;252:115282
European journal of medicinal chemistry 2023 Apr 5;252:115282
Inflammation Control and Tumor Growth Inhibition of Ovarian Cancer by Targeting Adhesion Molecules of E-Selectin.
Yang B, Yin S, Zhou Z, Huang L, Xi M
Cancers 2023 Apr 4;15(7)
Cancers 2023 Apr 4;15(7)
Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy.
Zhong Y, Wang L, Jin R, Liu J, Luo R, Zhang Y, Zhu L, Peng X
Nutrients 2023 Apr 30;15(9)
Nutrients 2023 Apr 30;15(9)
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Abdurahman A, Li Y, Jia SZ, Xu XW, Lin SJ, Ouyang P, Jun He Z, Zhang ZH, Liu Q, Xu Y, Song GL
Metallomics : integrated biometal science 2023 Apr 3;15(4)
Metallomics : integrated biometal science 2023 Apr 3;15(4)
Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex.
Cai S, Zhang C, Zhuang Z, Zhang S, Ma L, Yang S, Zhou T, Wang Z, Xie W, Jin S, Zhao J, Guan X, Wu J, Cui J, Wu Y
Signal transduction and targeted therapy 2023 Apr 26;8(1):170
Signal transduction and targeted therapy 2023 Apr 26;8(1):170
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Fan J, Liu M, Li X, Gao S, Wang Y, Li A, Chen L, Zhou D, Chen H, Xu Z, Wu Z, Wu K
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Antioxidant, Immunostimulatory, and Anticancer Properties of Hydrolyzed Wheat Bran Mediated through Macrophages Stimulation.
Tomé-Sánchez I, Martínez-Villaluenga C, Martín-Diana AB, Rico D, Jiménez-Pulido I, Frias J, Dia VP
International journal of molecular sciences 2023 Apr 18;24(8)
International journal of molecular sciences 2023 Apr 18;24(8)
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Zhang ZF, Liu F, Zhang HR, Liu B, Zheng SQ, Ye WQ, Ding JN, Zhou ZJ, Luo HX, Wu F, Guo XM, Zhou JY, Guo YH
Discover oncology 2023 Apr 13;14(1):43
Discover oncology 2023 Apr 13;14(1):43
Sulforaphane suppresses paraquat-induced oxidative damage in bovine in vitro-matured oocytes through Nrf2 transduction pathway.
Feng Z, Wang T, Sun Y, Chen S, Hao H, Du W, Zou H, Yu D, Zhu H, Pang Y
Ecotoxicology and environmental safety 2023 Apr 1;254:114747
Ecotoxicology and environmental safety 2023 Apr 1;254:114747
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Luo M, Cao S, Lv D, He L, He Z, Li L, Li Y, Luo S, Chang Q
Frontiers in cardiovascular medicine 2022;9:922705
Frontiers in cardiovascular medicine 2022;9:922705
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Chen Y, Qiao S, Liu H, Xing H, Chen P
Frontiers in nutrition 2022;9:911838
Frontiers in nutrition 2022;9:911838
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Pei Z, Wu M, Yu H, Long G, Gui Z, Li X, Chen H, Jia Z, Xia W
Frontiers in medicine 2022;9:873739
Frontiers in medicine 2022;9:873739
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Zou P, Zhang X, Zhang R, Chai X, Zhao Y, Li E, Zhang Q, Yan R, Yang J, Liao B
Frontiers in molecular biosciences 2022;9:853654
Frontiers in molecular biosciences 2022;9:853654
Effect of Two Different Drug-Resistant Staphylococcus aureus Strains on the Physiological Properties of MAC-T Cells and Their Transcriptome Analysis.
Yan L, Yang Y, Ma X, Wei L, Wan X, Zhang Z, Ding J, Peng J, Liu G, Gou H, Wang C, Zhang X
Frontiers in veterinary science 2022;9:818928
Frontiers in veterinary science 2022;9:818928
6-Shogaol Inhibits Oxidative Stress-Induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 Axis.
Liu J, Li B, Li W, Pan T, Diao Y, Wang F
Frontiers in molecular biosciences 2022;9:808162
Frontiers in molecular biosciences 2022;9:808162
Effects of limonin treatment on the survival of random skin flaps in mice.
Zhang T, Huang Q, Gan K, Zhou K, Hu K, Ding W, Jin J, Li J
Frontiers in surgery 2022;9:1043239
Frontiers in surgery 2022;9:1043239
Calvatia Lilacina Extracts Exert Anti-Breast-Cancer Bioactivity through the Apoptosis Induction Dependent on Mitochondrial Reactive Oxygen Species and Caspase Activation.
Zeng Q, Singh R, Ye Y, Cheng S, Fan C, Zeng Q
Nutrition and cancer 2022;74(3):1058-1070
Nutrition and cancer 2022;74(3):1058-1070
Lycium barbarum polysaccharide attenuates Pseudomonas-aeruginosa pyocyanin-induced cellular injury in mice airway epithelial cells.
Lin X, Song F, Wu Y, Xue D, Wang Y
Food & nutrition research 2022;66
Food & nutrition research 2022;66
MiR-7015-3p Targets Nuclear Factor-Kappa-B-Inhibitor Alpha to Aggravate Hypoxia/Reoxygenation Injury in Cardiomyocytes Through the NF-κB Pathway.
Shen X, Tao J, Wang Z, Li G, Zhang Z, Li J, Diliar A
International heart journal 2022;63(5):881-892
International heart journal 2022;63(5):881-892
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Xiong W, Huang XL, Li CY, Wang XL, Lan HW, Wang TT, Chen ZL, Yang QP, Hu AL, Xia YF, Zhu FR, Zhou ZZ
Folia histochemica et cytobiologica 2022;60(4):323-334
Folia histochemica et cytobiologica 2022;60(4):323-334
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Huang ZW, Tan P, Yi XK, Chen H, Sun B, Shi H, Mou ZQ, Cheng YL, Li TX, Li Q, Fu WG
The American journal of Chinese medicine 2022;50(8):2185-2197
The American journal of Chinese medicine 2022;50(8):2185-2197
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.
Sun YS, Wang ZW, Gao Z, Zhao W, Thakur K, Zhong Q, Wei ZJ
Current research in food science 2022;5:904-917
Current research in food science 2022;5:904-917
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
Guan L, Wang F, Wang M, Han S, Cui Z, Xi S, Xu H, Li S
Oxidative medicine and cellular longevity 2022;2022:9613095
Oxidative medicine and cellular longevity 2022;2022:9613095
Artesunate Suppresses the Growth of Lung Cancer Cells by Downregulating the AKT/Survivin Signaling Pathway.
Zhang W, Ning N, Huang J
BioMed research international 2022;2022:9170053
BioMed research international 2022;2022:9170053
Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.
Yang CJ, Li X, Feng XQ, Chen Y, Feng JG, Jia J, Wei JC, Zhou J
Oxidative medicine and cellular longevity 2022;2022:8729398
Oxidative medicine and cellular longevity 2022;2022:8729398
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Yu Q, Lin J, Ma Q, Li Y, Wang Q, Chen H, Liu Y, Liu B
Journal of diabetes research 2022;2022:8679548
Journal of diabetes research 2022;2022:8679548
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Jiang QY, Li JM, Jing MR, Zhang YX, Zhang QQ, Cai CB, Wang D, Qi HW, Li T, Li YZ, Ji XY, Wu DD
Oxidative medicine and cellular longevity 2022;2022:8678363
Oxidative medicine and cellular longevity 2022;2022:8678363
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Ma H, Duan X, Zhang R, Li H, Guo Y, Tian Y, Huang M, Chen G, Wang Z, Li L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction.
Zheng Z, Yu Z, Xu B, Zhou Y, Xing Y, Li Q, Tang W, Peng F
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8630480
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8630480
Protective Effect of Phloretin against Hydrogen Peroxide-Induced Oxidative Damage by Enhancing Autophagic Flux in DF-1 Cells.
Song D, Liu F, Tao W, Wu X, Bi H, Li X, Shu J, Wang D
Oxidative medicine and cellular longevity 2022;2022:8359118
Oxidative medicine and cellular longevity 2022;2022:8359118
Keratin 8 Is an Inflammation-Induced and Prognosis-Related Marker for Pancreatic Adenocarcinoma.
Xiong F, Guo T, Wang X, Wu G, Liu W, Wang Q, Wang B, Chen Y
Disease markers 2022;2022:8159537
Disease markers 2022;2022:8159537
DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status.
Dong X, Hu F, Yi J, Zhang Y, Liu C, Geng P, Duan H, Wu CT, Zhang X, Wang H
Stem cells international 2022;2022:7590337
Stem cells international 2022;2022:7590337
Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21.
Huang R, Zou C, Zhang C, Wang X, Zou X, Xiang Z, Wang Z, Gui B, Lin T, Hu H
Oxidative medicine and cellular longevity 2022;2022:7142314
Oxidative medicine and cellular longevity 2022;2022:7142314
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Wu W, Gou H, Xiang B, Geng R, Dong J, Yang X, Chen D, Dai R, Chen L, Liu J
Journal of oncology 2022;2022:7099589
Journal of oncology 2022;2022:7099589
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Zhan L, Liu H, Zheng J, Meng J, Fu D, Pang L, Ji C
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Zhang YL, Li PB, Han X, Zhang B, Li HH
Oxidative medicine and cellular longevity 2022;2022:6196173
Oxidative medicine and cellular longevity 2022;2022:6196173
Brevilin A Inhibits VEGF-Induced Angiogenesis through ROS-Dependent Mitochondrial Dysfunction.
Wei B, Hao Z, Zheng H, Qin Y, Zhao F, Shi L
Oxidative medicine and cellular longevity 2022;2022:5888636
Oxidative medicine and cellular longevity 2022;2022:5888636
Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy.
Jiang RH, Dong CJ, Chen ZL, Cheng S, Yang JX, Gao WY
Oxidative medicine and cellular longevity 2022;2022:5668226
Oxidative medicine and cellular longevity 2022;2022:5668226
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
Liu G, Guan Y, Liu Y, Wang Y, Zhang J, Liu Y, Liu X
BioMed research international 2022;2022:5489553
BioMed research international 2022;2022:5489553
CORM-3 Attenuates Oxidative Stress-Induced Bone Loss via the Nrf2/HO-1 Pathway.
Jin C, Lin BH, Zheng G, Tan K, Liu GY, Yao Z, Xie J, Chen WK, Chen L, Xu TH, Huang CB, Wu ZY, Yang L
Oxidative medicine and cellular longevity 2022;2022:5098358
Oxidative medicine and cellular longevity 2022;2022:5098358
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Fang Q, Liu X, Ding J, Zhang Z, Chen G, Du T, Wang Y, Xu R
Oxidative medicine and cellular longevity 2022;2022:3773415
Oxidative medicine and cellular longevity 2022;2022:3773415
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Yi J, Peng F, Zhao J, Gong X
Journal of oncology 2022;2022:3565118
Journal of oncology 2022;2022:3565118
Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway.
Wang S, Tan J, Chen L, Wang J
Journal of oncology 2022;2022:2956888
Journal of oncology 2022;2022:2956888
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
Li B, Lu ZY, Jiang SD, Jiang LS, Zheng XF
Oxidative medicine and cellular longevity 2022;2022:2912276
Oxidative medicine and cellular longevity 2022;2022:2912276
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Liu WZ, Ma ZJ, Kang JH, Lin AX, Wang ZH, Chen HW, Guo XD, He XG, Kang XW
Mediators of inflammation 2022;2022:2579003
Mediators of inflammation 2022;2022:2579003
SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis.
Zhou X, Lin L, Qi Y, Xu M, Xu Q, Wang Y, Qu J
Disease markers 2022;2022:2562595
Disease markers 2022;2022:2562595
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
Yin Z, Gao D, Du K, Han C, Liu Y, Wang Y, Gao X
Oxidative medicine and cellular longevity 2022;2022:2524832
Oxidative medicine and cellular longevity 2022;2022:2524832
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Qi S, Yan Q, Wang Z, Liu D, Zhan M, Du J, Chen L
PPAR research 2022;2022:2212996
PPAR research 2022;2022:2212996
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
Hu H, Luo Z, Liu X, Huang L, Lu X, Ding R, Duan C, He Y
International journal of endocrinology 2022;2022:2009753
International journal of endocrinology 2022;2022:2009753
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Wang G, Ma L, Wang B, Gao F, Li J, Cai H, Wang J, Zhang T, Guo H, Xie P, Li Y
Mediators of inflammation 2022;2022:1478181
Mediators of inflammation 2022;2022:1478181
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Wang M, Yang X, Zhou Q, Guo Y, Chen Y, Song L, Yang J, Li L, Luo L
Oxidative medicine and cellular longevity 2022;2022:1330928
Oxidative medicine and cellular longevity 2022;2022:1330928
Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell.
Gong L, Chen B, Chen J, Li Y
Neural plasticity 2022;2022:1298692
Neural plasticity 2022;2022:1298692
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
Jia C, Li X, Pan J, Ma H, Wu D, Lu H, Wang W, Zhang X, Yi X
Oxidative medicine and cellular longevity 2022;2022:1135827
Oxidative medicine and cellular longevity 2022;2022:1135827
PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer.
Chen YG, Liu HX, Hong Y, Dong PZ, Liu SY, Gao YR, Lu D, Li T, Wang DY, Wu DD, Ji XY
International journal of biological sciences 2022;18(9):3605-3620
International journal of biological sciences 2022;18(9):3605-3620
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
Wen H, Zhong Y, Yin Y, Qin K, Yang L, Li D, Yu W, Yang C, Deng Z, Hong K
International journal of biological sciences 2022;18(7):2898-2913
International journal of biological sciences 2022;18(7):2898-2913
CIRBP-OGFR axis safeguards against cardiomyocyte apoptosis and cardiotoxicity induced by chemotherapy.
Liu C, Cheng X, Xing J, Li J, Li Z, Jian D, Wang Y, Wang S, Li R, Zhang W, Shao D, Ma X, Chen X, Shen J, Shi C, Guo Z, Wang W, Fan T, Liu L, Tang H
International journal of biological sciences 2022;18(7):2882-2897
International journal of biological sciences 2022;18(7):2882-2897
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y
International journal of biological sciences 2022;18(6):2639-2651
International journal of biological sciences 2022;18(6):2639-2651
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca(2+)-FOXO1 pathway.
Huang JC, Duan CC, Jin S, Sheng CB, Wang YS, Yue ZP, Guo B
International journal of biological sciences 2022;18(5):2047-2059
International journal of biological sciences 2022;18(5):2047-2059
Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics.
Zhang Q, Luo P, Chen J, Yang C, Xia F, Zhang J, Tang H, Liu D, Gu L, Shi Q, He X, Yang T, Wang J
International journal of biological sciences 2022;18(5):2003-2017
International journal of biological sciences 2022;18(5):2003-2017
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
Dong L, Jiang H, Chen K, Xie J, An Q, Deng F, Sun Z, Liu Y, Zhou J, Zhang L, Lu X, Wang M, Chen Z, Zou X, Zuo D
International journal of biological sciences 2022;18(4):1580-1593
International journal of biological sciences 2022;18(4):1580-1593
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs.
Liu W, Yan B, Yu H, Ren J, Peng M, Zhu L, Wang Y, Jin X, Yi L
International journal of biological sciences 2022;18(4):1401-1414
International journal of biological sciences 2022;18(4):1401-1414
Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin.
Xiao J, Li Y, Cheng G, Xu G
Open medicine (Warsaw, Poland) 2022;17(1):768-780
Open medicine (Warsaw, Poland) 2022;17(1):768-780
Zinc Oxide Particles Can Cause Ovarian Toxicity by Oxidative Stress in Female Mice Model.
Xu Y, Zhao Y, Liu S, Lv S, Chen L, Wang W, Feng Y, Fu F, Xu H
International journal of nanomedicine 2022;17:4947-4960
International journal of nanomedicine 2022;17:4947-4960
Microglial infiltration mediates cognitive dysfunction in rat models of hypothalamic obesity via a hypothalamic-hippocampal circuit involving the lateral hypothalamic area.
Song C, Wei W, Wang T, Zhou M, Li Y, Xiao B, Huang D, Gu J, Shi L, Peng J, Jin D
Frontiers in cellular neuroscience 2022;16:971100
Frontiers in cellular neuroscience 2022;16:971100
Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
Wang Y, Luo K, Li J, Liao Y, Liao C, Chen WS, Chen M, Ao L
Frontiers in cellular neuroscience 2022;16:884788
Frontiers in cellular neuroscience 2022;16:884788
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Xiao S, Zhou Y, Wang Q, Yang D
Drug design, development and therapy 2022;16:4411-4428
Drug design, development and therapy 2022;16:4411-4428
Magnesium Lithospermate B Protects Against Cisplatin-Induced Acute Kidney Injury via Alleviating Mitochondrial Dysfunction.
Shen D, Guo M, Geng X, Yu J, Zhang Z, Lin J, Lin P, Ding X, Xu X
Drug design, development and therapy 2022;16:2293-2304
Drug design, development and therapy 2022;16:2293-2304
Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction.
Fan ZG, Xu Y, Chen X, Ji MY, Ma GS
Drug design, development and therapy 2022;16:2017-2030
Drug design, development and therapy 2022;16:2017-2030
Expression and potential role of FOSB in glioma.
Qi M, Sun LA, Zheng LR, Zhang J, Han YL, Wu F, Zhao J, Niu WH, Fei MX, Jiang XC, Zhou ML
Frontiers in molecular neuroscience 2022;15:972615
Frontiers in molecular neuroscience 2022;15:972615
The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells.
Zhao J, Liu H, Huang Z, Yang R, Gong L
Frontiers in molecular neuroscience 2022;15:824762
Frontiers in molecular neuroscience 2022;15:824762
Over-expression of miR-193a-3p regulates the apoptosis of colorectal cancer cells by targeting PAK3.
Ma T, Li H, Yang W, Liu Q, Yan H
American journal of translational research 2022;14(2):1361-1375
American journal of translational research 2022;14(2):1361-1375
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Zheng X, Liu B, Liu X, Li P, Zhang P, Ye F, Zhao T, Kuang Y, Chen W, Jin X, Li Q
Journal of Cancer 2022;13(2):669-680
Journal of Cancer 2022;13(2):669-680
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Huang D, Wang P, Chen J, Li Y, Zhu M, Tang Y, Zhou W
Frontiers in immunology 2022;13:995791
Frontiers in immunology 2022;13:995791
Licoricidin combats gastric cancer by targeting the ICMT/Ras pathway in vitro and in vivo.
Ma H, Wu F, Bai Y, Wang T, Ma S, Guo L, Liu G, Leng G, Kong Y, Zhang Y
Frontiers in pharmacology 2022;13:972825
Frontiers in pharmacology 2022;13:972825
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Wang J, Wang K, Ding L, Zhao P, Zhang C, Wang H, Yang Z, Liu Z
Frontiers in pharmacology 2022;13:969892
Frontiers in pharmacology 2022;13:969892
Therapeutic effect and mechanism of combination therapy with ursolic acid and insulin on diabetic nephropathy in a type I diabetic rat model.
Liu Y, Zheng JY, Wei ZT, Liu SK, Sun JL, Mao YH, Xu YD, Yang Y
Frontiers in pharmacology 2022;13:969207
Frontiers in pharmacology 2022;13:969207
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154
Frontiers in endocrinology 2022;13:962154
Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis.
Zhang Y, Duan C, Wu S, Ma J, Liu Y, Li W, Wang T, Yang L, Cheng K, Zhuang R
Frontiers in immunology 2022;13:936689
Frontiers in immunology 2022;13:936689
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H(2)O(2)-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Yang T, Lin X, Li H, Zhou X, Fan F, Yang J, Luo Y, Liu X
Frontiers in pharmacology 2022;13:927871
Frontiers in pharmacology 2022;13:927871
Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation.
Xia B, Li Q, Wu J, Yuan X, Wang F, Lu X, Huang C, Zheng K, Yang R, Yin L, Liu K, You Q
Frontiers in pharmacology 2022;13:922484
Frontiers in pharmacology 2022;13:922484
Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.
Han J, Zhang Z, Zhang Z, Yang S
Frontiers in pharmacology 2022;13:918966
Frontiers in pharmacology 2022;13:918966
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Xin M, Gao Q, Xiang X, Xu J, Jiao Y, Li X, Zhang X, Jia X
Frontiers in pharmacology 2022;13:890974
Frontiers in pharmacology 2022;13:890974
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Li D, Zhao H, Xu P, Lin Q, Zhao T, Li C, Cui ZK, Tian G
Frontiers in pharmacology 2022;13:887833
Frontiers in pharmacology 2022;13:887833
High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia.
Ren Z, Huang X, Lv Q, Lei Y, Shi H, Wang F, Wang M
Frontiers in genetics 2022;13:882004
Frontiers in genetics 2022;13:882004
Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.
Qin X, Liu B, Gao F, Hu Y, Chen Z, Xu J, Zhang X
Frontiers in physiology 2022;13:856699
Frontiers in physiology 2022;13:856699
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Yu TT, Han N, Li LG, Peng XC, Li QR, Xu HZ, Wang XY, Yang ZY, Chen X, Wang MF, Li TF
Frontiers in pharmacology 2022;13:837784
Frontiers in pharmacology 2022;13:837784
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Lin X, Wei Y, Li Y, Xiong Y, Fang B, Li C, Huang Q, Huang R, Wei J
Frontiers in pharmacology 2022;13:801982
Frontiers in pharmacology 2022;13:801982
PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling.
Cao YJ, Li JY, Wang PX, Lin ZR, Yu WJ, Zhang JG, Lu J, Liu PQ
Frontiers in pharmacology 2022;13:798436
Frontiers in pharmacology 2022;13:798436
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T
Frontiers in endocrinology 2022;13:781149
Frontiers in endocrinology 2022;13:781149
Comprehensive analysis of hypoxia-related genes for prognosis value, immune status, and therapy in osteosarcoma patients.
Han T, Wu Z, Zhang Z, Liang J, Xia C, Yan H
Frontiers in pharmacology 2022;13:1088732
Frontiers in pharmacology 2022;13:1088732
Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis.
Li W, Yang K, Li B, Wang Y, Liu J, Chen D, Diao Y
Frontiers in pharmacology 2022;13:1060104
Frontiers in pharmacology 2022;13:1060104
Sanguisorba officinalis L. suppresses non-small cell lung cancer via downregulating the PI3K/AKT/mTOR signaling pathway based on network pharmacology and experimental investigation.
Li H, Lin J, Yang F, Deng J, Lai J, Zeng J, Zou W, Jiang N, Huang Q, Li H, Liu J, Li M, Zhong Z, Wu J
Frontiers in pharmacology 2022;13:1054803
Frontiers in pharmacology 2022;13:1054803
Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-A(Thr288)-geminin dual signaling pathways.
Zhao H, Jia P, Nanding K, Wu M, Bai X, Morigen M, Fan L
Frontiers in pharmacology 2022;13:1046269
Frontiers in pharmacology 2022;13:1046269
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Guo K, Liu R, Jing R, Wang L, Li X, Zhang K, Fu M, Ye J, Hu Z, Zhao W, Xu N
Frontiers in pharmacology 2022;13:1036013
Frontiers in pharmacology 2022;13:1036013
Depletion of PARP10 inhibits the growth and metastatic potential of oral squamous cell carcinoma.
Zhou Z, Wei B, Liu Y, Liu T, Zeng S, Gan J, Qi G
Frontiers in genetics 2022;13:1035638
Frontiers in genetics 2022;13:1035638
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Ma T, Jia L, Zhao J, Lv L, Yu Y, Ruan H, Song X, Chen H, Li X, Zhang J, Gao L
Frontiers in pharmacology 2022;13:1027553
Frontiers in pharmacology 2022;13:1027553
BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model.
Lu Z, Sun GF, Pan XA, Qu XH, Yang P, Chen ZP, Han XJ, Wang T
Frontiers in pharmacology 2022;13:1025551
Frontiers in pharmacology 2022;13:1025551
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Ge F, Li Z, Hu J, Pu Y, Zhao F, Kong L
Frontiers in pharmacology 2022;13:1002565
Frontiers in pharmacology 2022;13:1002565
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Zheng W, Wang K, Wu Y, Yan G, Zhang C, Li Z, Wang L, Chen S
Theranostics 2022;12(17):7289-7306
Theranostics 2022;12(17):7289-7306
A miR-137-XIAP axis contributes to the sensitivity of TRAIL-induced cell death in glioblastoma.
Geng F, Yang F, Liu F, Zhao J, Zhang R, Hu S, Zhang J, Zhang X
Frontiers in oncology 2022;12:870034
Frontiers in oncology 2022;12:870034
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
Tan M, Wang H, Gao C, Jiang Z, Yin Y, Xing R, Hu L, Xu J, Zhang M, Xie Y
Frontiers in oncology 2022;12:844214
Frontiers in oncology 2022;12:844214
Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.
Wang FF, Zhao PY, He XJ, Jiang K, Wang TS, Xiao JW, Sun DB, Guo DH
Frontiers in cellular and infection microbiology 2022;12:827750
Frontiers in cellular and infection microbiology 2022;12:827750
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Zhang L, Li C, Fu L, Yu Z, Xu G, Zhou J, Shen M, Feng Z, Zhu H, Xie T, Zhou L, Zhou X
PeerJ 2022;10:e12759
PeerJ 2022;10:e12759
A nanobody-based molecular toolkit for ubiquitin-proteasome system explores the main role of survivin subcellular localization.
Miao H, Liu C, Ouyang H, Zhang P, Liu Y, Zhang C, Deng C, Fu Y, Niu J, Zheng W, You F, Yang Y, Ma X
Frontiers in bioengineering and biotechnology 2022;10:952237
Frontiers in bioengineering and biotechnology 2022;10:952237
A mitochondria-targeted nano-platform for pancreatic cancer therapy.
Tan X, Zhu X, Xu D, Shi Y, Wang Z, Cao M, Hu K, Zhao L, Zhao J, Miao M, Zeng H, Wu X
Frontiers in chemistry 2022;10:951434
Frontiers in chemistry 2022;10:951434
Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation.
Cheng X, Zhang R, Wei S, Huang J, Zhai K, Li Y, Gao B
Frontiers in public health 2022;10:900751
Frontiers in public health 2022;10:900751
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Dong Y, Lv D, Zhao Z, Xu Z, Hu Z, Tang B
Frontiers in bioengineering and biotechnology 2022;10:892015
Frontiers in bioengineering and biotechnology 2022;10:892015
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Wang Z, Zhang P, Zhao Y, Yu F, Wang S, Liu K, Cheng X, Shi J, He Q, Xia Y, Cheng L
Frontiers in bioengineering and biotechnology 2022;10:883118
Frontiers in bioengineering and biotechnology 2022;10:883118
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Li W, Wang X, Liu T, Zhang Q, Cao J, Jiang Y, Sun Q, Li C, Wang W, Wang Y
Frontiers in cell and developmental biology 2022;10:813370
Frontiers in cell and developmental biology 2022;10:813370
The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis.
Wang J, Wu X, Sun X, Zhang L, Wang Q, Qu J, Wang Y, Li Y
Frontiers in cell and developmental biology 2022;10:760466
Frontiers in cell and developmental biology 2022;10:760466
TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice.
Zhang J, Zhou X, Wan D, Yu L, Chen X, Yan T, Wu Z, Zheng M, Zhu F, Zhu H
Frontiers in cell and developmental biology 2022;10:757042
Frontiers in cell and developmental biology 2022;10:757042
Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma.
Peng Z, Li M, Wang Y, Yang H, Wei W, Liang M, Shi J, Liu R, Li R, Zhang Y, Liu J, Shi X, Wan R, Fu Y, Xie R, Wang Y
Frontiers in cell and developmental biology 2022;10:698282
Frontiers in cell and developmental biology 2022;10:698282
Ferulic acid ameliorates acetaminophen-induced acute liver injury by promoting AMPK-mediated protective autophagy.
Wu J, Zhou F, Fan G, Liu J, Wang Y, Xue X, Lyu X, Lin S, Li X
IUBMB life 2022 Sep;74(9):880-895
IUBMB life 2022 Sep;74(9):880-895
MiR-325-3p Alleviates Acute Pancreatitis via Targeting RIPK3.
Jia A, Yang ZW, Shi JY, Liu JM, Zhang K, Cui YF
Digestive diseases and sciences 2022 Sep;67(9):4471-4483
Digestive diseases and sciences 2022 Sep;67(9):4471-4483
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Li M, Xia M, Zhang Z, Tan Y, Li E, Guo Z, Fang M, Zhu Y, Hu Z
International journal of oncology 2022 Sep;61(3)
International journal of oncology 2022 Sep;61(3)
Expression levels of caspase-3 and gasdermin E and their involvement in the occurrence and prognosis of lung cancer.
Huang YL, Zhang GH, Zhu Q, Wu X, Wu LG
Cancer reports (Hoboken, N.J.) 2022 Sep;5(9):e1561
Cancer reports (Hoboken, N.J.) 2022 Sep;5(9):e1561
Acacetin antagonized lipotoxicity in pancreatic β-cells via ameliorating oxidative stress and endoplasmic reticulum stress.
Wang N, Gao Q, Shi J, Yulan C, Ji W, Sheng X, Zhang R
Molecular biology reports 2022 Sep;49(9):8727-8740
Molecular biology reports 2022 Sep;49(9):8727-8740
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Pan H, Yang L, Bai H, Luo J, Deng Y
Journal of ginseng research 2022 Sep;46(5):636-645
Journal of ginseng research 2022 Sep;46(5):636-645
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y, Mao X
The Journal of biological chemistry 2022 Sep;298(9):102314
The Journal of biological chemistry 2022 Sep;298(9):102314
Protective Effect of Shenfu Injection on Vascular Endothelial Damage in a Porcine Model of Hemorrhagic Shock.
Zhang MQ, Zhang Q, Yuan W, Wu JY, Liang Y, Qin HJ, Li CS
Chinese journal of integrative medicine 2022 Sep;28(9):794-801
Chinese journal of integrative medicine 2022 Sep;28(9):794-801
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Fan M, Xiong X, Han L, Zhang L, Gao S, Liu L, Wang X, Huang C, Tong D, Yang J, Zhao L, Shao Y
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Jiang T, Shen S, Wang L, Zhao M, Li Y, Huang S
Applied biochemistry and biotechnology 2022 Sep;194(9):4093-4104
Applied biochemistry and biotechnology 2022 Sep;194(9):4093-4104
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Wang TY, Hu YJ, Wang X, Li YF, Zhang F, Yan YD, Dou WT, Cheng CY, Xu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Improvement of anticancer effect of berberine by salt formation modifications.
Xu F, Liu M, Liao Y, Zhou Y, Zhang P, Zeng Y, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154314
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154314
THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours.
Sun J, Zhang Q, Sun X, Xue A, Gao X, Shen K
Cell communication and signaling : CCS 2022 Sep 8;20(1):138
Cell communication and signaling : CCS 2022 Sep 8;20(1):138
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
Wang Z, Wang MM, Geng Y, Ye CY, Zang YS
Journal of translational medicine 2022 Sep 5;20(1):402
Journal of translational medicine 2022 Sep 5;20(1):402
SIRT1 modifies DNA methylation linked to synaptic deficits induced by Pb in vitro and in vivo.
Wang R, Yang M, Wu Y, Liu R, Liu M, Li Q, Su X, Xin Y, Huo W, Deng Q, Ba Y, Huang H
International journal of biological macromolecules 2022 Sep 30;217:219-228
International journal of biological macromolecules 2022 Sep 30;217:219-228
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
Small extracellular vesicles of hypoxic endothelial cells regulate the therapeutic potential of adipose-derived mesenchymal stem cells via miR-486-5p/PTEN in a limb ischemia model.
Shen Z, Wang W, Chen J, Chen B, Tang Y, Hou J, Li J, Liu S, Mei Y, Zhang L, Lu S
Journal of nanobiotechnology 2022 Sep 24;20(1):422
Journal of nanobiotechnology 2022 Sep 24;20(1):422
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Dang Y, He Q, Yang S, Sun H, Liu Y, Li W, Tang Y, Zheng Y, Wu T
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma.
Shi Y, Cui X, Jiang T, Pan Y, Lin Y, Feng X, Ding Z, Yang C, Tan Y, Wang H, Dong L
Cell death & disease 2022 Sep 19;13(9):799
Cell death & disease 2022 Sep 19;13(9):799
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
He D, Liu Y, Li J, Wang H, Ye B, He Y, Li Z, Gao X, Fu S, Liu D
Cells 2022 Sep 19;11(18)
Cells 2022 Sep 19;11(18)
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.
Chang X, Wang J, Bian J, Liu Z, Guo M, Li Z, Wu Y, Zhai X, Zuo D
Toxicology and applied pharmacology 2022 Sep 1;450:116156
Toxicology and applied pharmacology 2022 Sep 1;450:116156
Oleuropein attenuates testicular ischemia-reperfusion by inhibiting apoptosis and inflammation.
Xu LZ, He KX, Ning JZ, Cheng F
Tissue & cell 2022 Oct;78:101876
Tissue & cell 2022 Oct;78:101876
Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.
Kaixuan Z, Dong Z, Huiwei B, Lijing LI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794
Mechanism of Thymus Rejuvenation in Elderly Macaques.
Wang YY, Chang L, Zhu GH, Li GH, Kong QP, Lv LB, Wang Q, Tian C, Li Y, Zhu XQ, Pan XH
Rejuvenation research 2022 Oct;25(5):223-232
Rejuvenation research 2022 Oct;25(5):223-232
Anodal transcranial direct current stimulation alleviates cognitive impairment in an APP/PS1 model of Alzheimer's disease in the preclinical stage.
Luo YP, Liu Z, Wang C, Yang XF, Wu XY, Tian XL, Wen HZ
Neural regeneration research 2022 Oct;17(10):2278-2285
Neural regeneration research 2022 Oct;17(10):2278-2285
Mechanical stretch aggravates vascular smooth muscle cell apoptosis and vascular remodeling by downregulating EZH2.
Zhong HY, Yuan C, Liu XL, Wang QQ, Li X, Zhao YC, Li X, Liu DD, Zheng TF, Zhang M
The international journal of biochemistry & cell biology 2022 Oct;151:106278
The international journal of biochemistry & cell biology 2022 Oct;151:106278
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Wang X, Duan C, Li Y, Lu H, Guo K, Ge X, Chen T, Shang Y, Liu H, Zhang D
International immunopharmacology 2022 Oct;111:109083
International immunopharmacology 2022 Oct;111:109083
SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.
Yang L, Zhu J, Yang L, Gan Y, Hu D, Zhao J, Zhao Y
International immunopharmacology 2022 Oct;111:109079
International immunopharmacology 2022 Oct;111:109079
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Hao M, Ding C, Peng X, Chen H, Dong L, Zhang Y, Chen X, Liu W, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365
Haizao Yuhu decoctions including three species of glycyrrhiza protected against propylthiouracil-induced goiter with hypothyroidism in rats via the AMPK/mTOR pathway.
Li N, Li M, Xiu L, Liao W, Ren Y, Liu H, Chen S, Chen F, Yu X, Fan A, Huo M, He J, Zhong G
Journal of ethnopharmacology 2022 Oct 5;296:115443
Journal of ethnopharmacology 2022 Oct 5;296:115443
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
Luan H, Yan L, Zhao Y, Ding X, Cao L
Discover oncology 2022 Oct 3;13(1):98
Discover oncology 2022 Oct 3;13(1):98
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345
Aging 2022 Oct 27;14(20):8321-8345
Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma.
Gao Z, Li M, Yao F, Xia X, Duan T, Meng J, Huang Y, He Y, Saro A, Huang J
International journal of molecular sciences 2022 Oct 26;23(21)
International journal of molecular sciences 2022 Oct 26;23(21)
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Tai H, Cui XZ, He J, Lan ZM, Li SM, Li LB, Yao SC, Jiang XL, Meng XS, Kuang JS
Aging 2022 Oct 20;14(20):8302-8320
Aging 2022 Oct 20;14(20):8302-8320
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Zhao Y, Lin J, Li J, Bwalya C, Xu Y, Niu Y, Zhang Y, Wu J, Xu Y, Chen J, Ye S, Lin L
International journal of molecular sciences 2022 Oct 18;23(20)
International journal of molecular sciences 2022 Oct 18;23(20)
Geniposide attenuates spermatogenic dysfunction via inhibiting endoplasmic reticulum stress in male mice.
Chi YN, Ye RJ, Yang JM, Hai DM, Liu N, Ren JW, Du J, Lan XB, Yu JQ, Ma L
Chemico-biological interactions 2022 Oct 1;366:110144
Chemico-biological interactions 2022 Oct 1;366:110144
New insights into the interaction between duodenal toxicity and microbiota disorder under copper exposure in chicken: Involving in endoplasmic reticulum stress and mitochondrial toxicity.
Ma F, Huo Y, Li H, Yang F, Liao J, Han Q, Li Y, Pan J, Hu L, Guo J, Tang Z
Chemico-biological interactions 2022 Oct 1;366:110132
Chemico-biological interactions 2022 Oct 1;366:110132
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Zheng H, Liu Q, Wang S, Liu X, Ma M, Shen T, Wang X, Ren D
Chemico-biological interactions 2022 Oct 1;366:110125
Chemico-biological interactions 2022 Oct 1;366:110125
Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.
Chen Y, Liu H, Zheng Q, Li H, You H, Feng Y, Feng W
Life sciences 2022 Oct 1;306:120826
Life sciences 2022 Oct 1;306:120826
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).
He Z, Cheng M, Hu J, Liu L, Liu P, Chen L, Cao D, Tang J
Journal of translational medicine 2022 Oct 1;20(1):443
Journal of translational medicine 2022 Oct 1;20(1):443
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Zhou Y, Li ZX, Liu YT, Xu ZC, Hu Y, Lv W, Yang ZY, Sheng YM, Liu S
Brain research bulletin 2022 Oct 1;188:203-213
Brain research bulletin 2022 Oct 1;188:203-213
Naringenin induces endoplasmic reticulum stress-mediated cell apoptosis and autophagy in human oral squamous cell carcinoma cells.
Liu JF, Chang TM, Chen PH, Lin JS, Tsai YJ, Wu HM, Lee CJ
Journal of food biochemistry 2022 Nov;46(11):e14221
Journal of food biochemistry 2022 Nov;46(11):e14221
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Zhou Z, Dong Y, Li N, Niu M, Wang S, Zhou Y, Sun Z, Chu P, Tang Z
Cell biology international 2022 Nov;46(11):1801-1813
Cell biology international 2022 Nov;46(11):1801-1813
AGR2-induced cholesterol synthesis drives lovastatin resistance that is overcome by combination therapy with allicin.
Sheng N, Wang YQ, Wang CF, Jia MQ, Niu HM, Lu QQ, Wang YN, Feng D, Zheng XX, Yuan HQ
Acta pharmacologica Sinica 2022 Nov;43(11):2905-2916
Acta pharmacologica Sinica 2022 Nov;43(11):2905-2916
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Liu N, Li Y, Yang Y, Shu L, Liu Y, Wu Y, Sun D, Kang Z, Zhang Y, Ni D, Wei Z, Li S, Yang M, Wang Y, Sun J, Yang X
Experimental neurology 2022 Nov;357:114180
Experimental neurology 2022 Nov;357:114180
LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis.
Wei W, Lin C, Hu R, Huang J, Chen X, Zhou L, Wei J, Deng YB, Wang CF
Molecular medicine reports 2022 Nov;26(5)
Molecular medicine reports 2022 Nov;26(5)
Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells.
Wang J, Lai X, Yuan D, Liu Y, Wang J, Liang Y
Food research international (Ottawa, Ont.) 2022 Nov;161:111816
Food research international (Ottawa, Ont.) 2022 Nov;161:111816
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Zhan L, Zheng J, Meng J, Fu D, Pang L, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Wang Y, Zhu M, Liang J, Zhang N, Sun D, Li H, Chen L
Bioorganic chemistry 2022 Nov;128:106067
Bioorganic chemistry 2022 Nov;128:106067
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Zhou X, Li X, Yi K, Liang C, Geng S, Zhu J, Xie C, Zhong C
Bioorganic chemistry 2022 Nov;128:106034
Bioorganic chemistry 2022 Nov;128:106034
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Deng YW, Liu F, Li ZT, Gao JH, Zhao Y, Yang XL, Xia YL
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1192-1202
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1192-1202
Human Umbilical Cord-Derived Mesenchymal Stem Cells Repair SU5416-Injured Emphysema by Inhibiting Apoptosis via Rescuing VEGF-VEGFR2-AKT Pathway in Rats.
Chen Q, Lv L, Zheng C, Pan H, Xu J, Lin J, Deng Z, Qian W
International journal of stem cells 2022 Nov 30;15(4):395-404
International journal of stem cells 2022 Nov 30;15(4):395-404
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Xu P, Chang J, Ma G, Liao F, Xu T, Wu Y, Yin Z
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury.
Liu B, Ding C, Tang W, Zhang C, Gu Y, Wang Z, Yu T, Li Z
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Pt(IV) Prodrug as a Potential Antitumor Agent with APE1 Inhibitory Activity.
Yuan Y, Fu D, Xu Y, Wang X, Deng X, Zhou S, Du F, Cui X, Deng Y, Tang Z
Journal of medicinal chemistry 2022 Nov 24;65(22):15344-15357
Journal of medicinal chemistry 2022 Nov 24;65(22):15344-15357
Mupirocin blocks imiquimod-induced psoriasis-like skin lesion by inhibiting epidermal isoleucyl-tRNA synthetase.
Yan BX, Chen XY, Wang ZY, Cui YZ, Landeck L, Fu NC, Yang XY, Xu F, Zhou Y, Chen JQ, Man XY
Cell communication and signaling : CCS 2022 Nov 22;20(1):185
Cell communication and signaling : CCS 2022 Nov 22;20(1):185
SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.
Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, Liu N, Gu J, Xu D
Nature communications 2022 Nov 22;13(1):7153
Nature communications 2022 Nov 22;13(1):7153
Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells.
Tian Z, Yang L, Huang M, Sun C, Chen M, Zhao W, Peng J, Guo G
Molecules (Basel, Switzerland) 2022 Nov 21;27(22)
Molecules (Basel, Switzerland) 2022 Nov 21;27(22)
Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization.
Zhang L, Jin GZ, Li D
Cancers 2022 Nov 21;14(22)
Cancers 2022 Nov 21;14(22)
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Peng S, Zhao D, Li Q, Wang M, Zhang S, Pang K, Huang J, Lu F, Chen H, Zhang W
Cells 2022 Nov 2;11(21)
Cells 2022 Nov 2;11(21)
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031
Nature communications 2022 Nov 17;13(1):7031
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
Wang R, Zhao J, Jin J, Tian Y, Lan L, Wang X, Zhu L, Wang J
Lipids in health and disease 2022 Nov 16;21(1):121
Lipids in health and disease 2022 Nov 16;21(1):121
CD93 promotes acute myeloid leukemia development and is a potential therapeutic target.
Jia J, Liu B, Wang D, Wang X, Song L, Ren Y, Guo Z, Ma K, Cui C
Experimental cell research 2022 Nov 15;420(2):113361
Experimental cell research 2022 Nov 15;420(2):113361
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G
European journal of medicinal chemistry 2022 Nov 15;242:114674
European journal of medicinal chemistry 2022 Nov 15;242:114674
GRP94 Inhabits the Immortalized Porcine Hepatic Stellate Cells Apoptosis under Endoplasmic Reticulum Stress through Modulating the Expression of IGF-1 and Ubiquitin.
Wang X, Xin H, Zhang C, Gu X, Hao Y
International journal of molecular sciences 2022 Nov 14;23(22)
International journal of molecular sciences 2022 Nov 14;23(22)
HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.
Duan SF, Zhang MM, Zhang X, Liu W, Zhang SH, Yang B, Dong Q, Han JG, Yu HL, Li T, Ji XY, Wu DD, Zhang XJ
Experimental cell research 2022 Nov 1;420(1):113341
Experimental cell research 2022 Nov 1;420(1):113341
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Wang J, Zhang L, Cao H, Shi X, Zhang X, Gao Z, Ikeda K, Yan T, Jia Y, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154022
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154022
Traditional Chinese medicine CFF-1 exerts a potent anti-tumor immunity to hinder tumor growth and metastasis in prostate cancer through EGFR/JAK1/STAT3 pathway to inhibit PD-1/PD-L1 checkpoint signaling.
Zhang Y, Wei Y, Jiang S, Dang Y, Yang Y, Zuo W, Zhu Q, Liu P, Gao Y, Lu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153939
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153939
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Yang X, Wang M, Zhou Q, Bai Y, Liu J, Yang J, Li L, Li G, Luo L
Molecular neurobiology 2022 May;59(5):2776-2798
Molecular neurobiology 2022 May;59(5):2776-2798
Impact and potential mechanism of effects of chronic moderate alcohol consumption on cardiac function in aldehyde dehydrogenase 2 gene heterozygous mice.
Hu Q, Chen H, Shen C, Zhang B, Weng X, Sun X, Liu J, Dong Z, Hu K, Ge J, Sun A
Alcoholism, clinical and experimental research 2022 May;46(5):707-723
Alcoholism, clinical and experimental research 2022 May;46(5):707-723
Selenium protects against cadmium-induced cardiac injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling.
Feng J, Yang F, Wu H, Xing C, Xue H, Zhang L, Zhang C, Hu G, Cao H
Environmental toxicology 2022 May;37(5):1185-1197
Environmental toxicology 2022 May;37(5):1185-1197
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer.
Cheng C, Wang J, Xu P, Zhang K, Xin Z, Zhao H, Ji Z, Zhang M, Wang D, He Y, Jing N, Fan L, Liu K, Li F, Liu C, Gong Y, Cui S, Sun Z, Sun D, Yao X, Li H, Zhang J, Zhang P, Dong B, Xue W, Qian X, Gao WQ, Zhu HH
Nature cancer 2022 May;3(5):565-580
Nature cancer 2022 May;3(5):565-580
Gasdermin E is required for induction of pyroptosis and severe disease during enterovirus 71 infection.
Dong S, Shi Y, Dong X, Xiao X, Qi J, Ren L, Xiang Z, Zhou Z, Wang J, Lei X
The Journal of biological chemistry 2022 May;298(5):101850
The Journal of biological chemistry 2022 May;298(5):101850
The application of CRISPR/Cas9 system in cervical carcinogenesis.
Gao C, Wu P, Yu L, Liu L, Liu H, Tan X, Wang L, Huang X, Wang H
Cancer gene therapy 2022 May;29(5):466-474
Cancer gene therapy 2022 May;29(5):466-474
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Yao W, Wang S, Du X, Lin C, Zhang J, Pan Z, Li Q
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1577-1585
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1577-1585
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Yu H, Wu S, Liu S, Li X, Gai Y, Lin H, Wang Y, Edwards H, Ge Y, Wang G
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
PM(2.5) induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
Ren F, Xu J, Zhang J, Xu X, Huang L, Sun W, Li R, Li F
Immunobiology 2022 May;227(3):152207
Immunobiology 2022 May;227(3):152207
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Cai J, Gao L, Wang Y, Li Y, Ye Z, Tong S, Yan T, Sun Q, Xu Y, Jiang H, Zhang S, Zhao L, Yang J, Chen Q
Translational oncology 2022 May;19:101391
Translational oncology 2022 May;19:101391
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Feng W, Wang J, Li B, Liu Y, Xu D, Cheng K, Zhuang J
The international journal of biochemistry & cell biology 2022 May;146:106206
The international journal of biochemistry & cell biology 2022 May;146:106206
Single-cell profiling-guided combination therapy of c-Fos and histone deacetylase inhibitors in diffuse large B-cell lymphoma.
Wang L, Wu Z, Xia Y, Lu X, Li J, Fan L, Qiao C, Qiu H, Gu D, Xu W, Li J, Jin H
Clinical and translational medicine 2022 May;12(5):e798
Clinical and translational medicine 2022 May;12(5):e798
Ubiquitin-specific protease 35 (USP35) mediates cisplatin-induced apoptosis by stabilizing BIRC3 in non-small cell lung cancer.
Liu C, Chen Z, Ding X, Qiao Y, Li B
Laboratory investigation; a journal of technical methods and pathology 2022 May;102(5):524-533
Laboratory investigation; a journal of technical methods and pathology 2022 May;102(5):524-533
Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy.
Zhang Y, Sun T, Li M, Lin Y, Liu Y, Tang S, Dai C
Antioxidants (Basel, Switzerland) 2022 May 5;11(5)
Antioxidants (Basel, Switzerland) 2022 May 5;11(5)
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
Zhang K, Lian S, Shen X, Zhao X, Zhao W, Li C
International journal of biological macromolecules 2022 May 31;208:890-900
International journal of biological macromolecules 2022 May 31;208:890-900
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
Li E, Xia M, Du Y, Long K, Ji F, Pan F, He L, Hu Z, Guo Z
eLife 2022 May 3;11
eLife 2022 May 3;11
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.
Yang G, Lu S, Jiang J, Weng J, Zeng X
International journal of molecular sciences 2022 May 27;23(11)
International journal of molecular sciences 2022 May 27;23(11)
Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors.
Jia D, Wang F, Lu Y, Hu P, Wang R, Li G, Liu R, Li J, Liu H, Fan Q, Yuan F
International journal of pharmaceutics 2022 May 25;620:121746
International journal of pharmaceutics 2022 May 25;620:121746
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Zhou T, Chen T, Lai B, Zhang W, Luo X, Xia D, Fu W, Xu J
Cellular and molecular life sciences : CMLS 2022 May 2;79(5):268
Cellular and molecular life sciences : CMLS 2022 May 2;79(5):268
Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating T lymphocytes.
Ren F, Zhang Y, Qin Y, Shang J, Wang Y, Wei P, Guo J, Jia H, Zhao T
Cell death discovery 2022 May 16;8(1):264
Cell death discovery 2022 May 16;8(1):264
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Gao L, Ye Z, Liu JH, Yang JA, Li Y, Cai JY, Wang YX, Tong SA, Deng G, Zhang S, Chen QX
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
Yang XX, Xu X, Wang MF, Xu HZ, Peng XC, Han N, Yu TT, Li LG, Li QR, Chen X, Wen Y, Li TF
Journal of nanobiotechnology 2022 May 14;20(1):230
Journal of nanobiotechnology 2022 May 14;20(1):230
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Wang R, Ren Q, Gao D, Paudel YN, Li X, Wang L, Zhang P, Wang B, Shang X, Jin M
Journal of ethnopharmacology 2022 May 10;289:115018
Journal of ethnopharmacology 2022 May 10;289:115018
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
Yang M, Feng J, Lan X, Tang Y, Zhang Y, Zhang H, Wang S
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):243-254
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):243-254
Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells.
Ma QL, Shen MO, Han N, Xu HZ, Peng XC, Li QR, Yu TT, Li LG, Xu X, Liu B, Chen X, Wang MF, Li TF
Photodiagnosis and photodynamic therapy 2022 Mar;37:102645
Photodiagnosis and photodynamic therapy 2022 Mar;37:102645
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Wang F, Luo Y, Zhang L, Younis M, Yuan L
Cancer gene therapy 2022 Mar;29(3-4):292-303
Cancer gene therapy 2022 Mar;29(3-4):292-303
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Jiang H, Niu Y, He Y, Li X, Xu Y, Liu X
Journal of cellular physiology 2022 Mar;237(3):1948-1963
Journal of cellular physiology 2022 Mar;237(3):1948-1963
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Kang H, Dong Y, Peng R, Liu H, Guo Q, Song K, Zhu M, Yu K, Wu W, Li F
Biochemical pharmacology 2022 Mar;197:114932
Biochemical pharmacology 2022 Mar;197:114932
Sevoflurane induced neurotoxicity in neonatal mice links to a GSK3β/Drp1-dependent mitochondrial fission and apoptosis.
Liu J, Li L, Xie P, Zhao X, Shi D, Zhang Y, Pan C, Li T
Free radical biology & medicine 2022 Mar;181:72-81
Free radical biology & medicine 2022 Mar;181:72-81
Catalpol alleviates myocardial ischemia reperfusion injury by activating the Nrf2/HO-1 signaling pathway.
Ge H, Lin W, Lou Z, Chen R, Shi H, Zhao Q, Lin Z
Microvascular research 2022 Mar;140:104302
Microvascular research 2022 Mar;140:104302
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Zhang J, Shang L, Jiang W, Wu W
Bioengineered 2022 Mar;13(3):7904-7918
Bioengineered 2022 Mar;13(3):7904-7918
Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification.
Jiang G, Sun C, Wang X, Mei J, Li C, Zhan H, Liao Y, Zhu Y, Mao J
Bioengineered 2022 Mar;13(3):5216-5235
Bioengineered 2022 Mar;13(3):5216-5235
Design, synthesis and biological evaluation of marine phidianidine-inspired derivatives against oxidized ldl-induced endothelial injury by activating Nrf2 anti-oxidation pathway.
Xie HX, Wang YH, Zhang JH, Zhang J, Zhong YN, Ge YX, Cheng ZQ, Jiang CS, Meng N
Bioorganic chemistry 2022 Mar;120:105606
Bioorganic chemistry 2022 Mar;120:105606
Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
Tian H, Wang G, Wang Q, Zhang B, Jiang G, Li H, Chai D, Fang L, Wang M, Zheng J
Cancer science 2022 Mar;113(3):875-890
Cancer science 2022 Mar;113(3):875-890
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways.
Li JJ, Liu ML, Lv JN, Chen RL, Ding K, He JQ
International immunopharmacology 2022 Mar;104:108510
International immunopharmacology 2022 Mar;104:108510
Blocking protease-activated receptor 4 alleviates liver injury induced by brain death.
Fang H, Yuan Z, Zhu Y, Tang H, Pang C, Li J, Shi J, Guo W, Zhang S
Biochemical and biophysical research communications 2022 Mar 5;595:47-53
Biochemical and biophysical research communications 2022 Mar 5;595:47-53
HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.
Ma H, Qi G, Han F, Lu W, Peng J, Li R, Yan S, Yuan C, Kong B
Cell death & disease 2022 Mar 24;13(3):263
Cell death & disease 2022 Mar 24;13(3):263
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Wang L, Chen J, Hu Y, Liao A, Zheng W, Wang X, Lan J, Shen J, Wang S, Yang F, Wang Y, Li Y, Chen D
Translational psychiatry 2022 Mar 22;12(1):114
Translational psychiatry 2022 Mar 22;12(1):114
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
Gu X, Zhang L, Sun W, Liu K, Xu H, Wu P, Gui M, Qu W
Chemical research in toxicology 2022 Mar 21;35(3):392-401
Chemical research in toxicology 2022 Mar 21;35(3):392-401
Engineering Lipusu with lysophosphatidylcholine for improved tumor cellular uptake and anticancer efficacy.
Li L, Zhan Q, Yi K, Chen N, Li X, Yang S, Hou X, Zhao J, Yuan X, Kang C
Journal of materials chemistry. B 2022 Mar 16;10(11):1833-1842
Journal of materials chemistry. B 2022 Mar 16;10(11):1833-1842
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancerthrough inhibiting GPX4 and enhancing ROS.
Han N, Li LG, Peng XC, Ma QL, Yang ZY, Wang XY, Li J, Li QR, Yu TT, Xu HZ, Xu X, Chen X, Wang MF, Li TF
European journal of pharmacology 2022 Mar 15;919:174797
European journal of pharmacology 2022 Mar 15;919:174797
Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H(+)] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.
Zhang Y, Liang X, Guan J, Jin J, Zhang Y, Xu F, Fu J
Toxicology and applied pharmacology 2022 Mar 15;439:115929
Toxicology and applied pharmacology 2022 Mar 15;439:115929
Inhibition of STAT3(Y705) phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Guo H, Xiao Y, Yuan Z, Yang X, Chen J, Chen C, Wang M, Xie L, Chen Q, Tong Y, Zhang Q, Bai Y
Cell death discovery 2022 Mar 14;8(1):116
Cell death discovery 2022 Mar 14;8(1):116
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Jin C, Min F, Zhong Y, Sun D, Luo R, Liu Q, Peng X
Toxicology letters 2022 Mar 1;356:110-120
Toxicology letters 2022 Mar 1;356:110-120
Oxidative stress activates Ryr2-Ca(2+) and apoptosis to promote PM(2.5)-induced heart injury of hyperlipidemia mice.
Meng M, Jia R, Wei M, Meng X, Zhang X, Du R, Sun W, Wang L, Song L
Ecotoxicology and environmental safety 2022 Mar 1;232:113228
Ecotoxicology and environmental safety 2022 Mar 1;232:113228
Microencapsulated islet transplantation alleviates podocyte injury in diabetic nephropathy via inhibiting Notch-1 signaling.
Yuan J, Lin F, Chen L, Huang H, Ni X, Pan X, Chen B, Cai Y
Transplant immunology 2022 Jun;72:101579
Transplant immunology 2022 Jun;72:101579
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Xie M, Xiong Z, Yin S, Xiong J, Li X, Jin L, Zhang F, Chen H, Lan P, Lian L
Digestive diseases and sciences 2022 Jun;67(6):2232-2243
Digestive diseases and sciences 2022 Jun;67(6):2232-2243
LncRNA small nucleolar RNA host gene 16 reduces sepsis-induced myocardial damage by regulating miR-421/suppressor of cytokine signaling 5 axis.
Yu M, Xie D, Hu CY, Cui Y
The Kaohsiung journal of medical sciences 2022 Jun;38(6):517-529
The Kaohsiung journal of medical sciences 2022 Jun;38(6):517-529
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Zhai X, Dai T, Chi Z, Zhao Z, Wu G, Yang S, Dong D
Environmental toxicology 2022 Jun;37(6):1332-1342
Environmental toxicology 2022 Jun;37(6):1332-1342
microRNA-486-5p is implicated in the cisplatin-induced apoptosis and acute inflammation response of renal tubular epithelial cells by targeting HAT1.
Lin FY, Han ST, Yu WM, Rao T, Ruan Y, Yuan R, Li HY, Ning JZ, Xia YQ, Xie JN, Qi YC, Zhou XJ, Cheng F
Journal of biochemical and molecular toxicology 2022 Jun;36(6):e23039
Journal of biochemical and molecular toxicology 2022 Jun;36(6):e23039
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Tai H, Tong YJ, Yu R, Yu Y, Yao SC, Li LB, Liu Y, Cui XZ, Kuang JS, Meng XS, Jiang XL
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Shi L, Wang X, Duan Y, Li K, Ren Y
Theriogenology 2022 Jun;185:43-49
Theriogenology 2022 Jun;185:43-49
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Cai J, Liang J, Zhang Y, Shen L, Lin H, Hu T, Zhan S, Xie M, Liang S, Xian M, Wang S
Pharmacological research 2022 Jun;180:106230
Pharmacological research 2022 Jun;180:106230
MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis.
Cui Y, Wang X, Lin F, Li W, Zhao Y, Zhu F, Yang H, Rao M, Li Y, Liang H, Dai M, Liu B, Chen L, Han D, Lu R, Peng W, Zhang Y, Song C, Luo Y, Pan P
Aging and disease 2022 Jun;13(3):899-909
Aging and disease 2022 Jun;13(3):899-909
Beneficial effects of genistein in suppression of proliferation, inhibition of metastasis, and induction of apoptosis in PC3 prostate cancer cells.
Shafiee G, Saidijam M, Tayebinia H, Khodadadi I
Archives of physiology and biochemistry 2022 Jun;128(3):694-702
Archives of physiology and biochemistry 2022 Jun;128(3):694-702
The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction.
Hu S, Gao Y, Gao R, Wang Y, Qu Y, Yang J, Wei X, Zhang F, Ge J
International immunopharmacology 2022 Jun;107:108658
International immunopharmacology 2022 Jun;107:108658
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Liang JJ, Yu WL, Yang L, Qin KM, Yin YP, Li D, Ni YH, Yan JJ, Zhong YX, Deng ZX, Hong K
European journal of medicinal chemistry 2022 Jun 5;236:114313
European journal of medicinal chemistry 2022 Jun 5;236:114313
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.
Wang YC, Zhang RH, Hu SC, Zhang H, Yang D, Zhang WL, Zhao YL, Cui DB, Li YJ, Pan WD, Liao SG, Zhou M
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Khan NH, Wang D, Wang W, Shahid M, Khattak S, Ngowi EE, Sarfraz M, Ji XY, Zhang CY, Wu DD
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Chen H, Dong L, Chen X, Ding C, Hao M, Peng X, Zhang Y, Zhu H, Liu W
Experimental gerontology 2022 Jun 15;163:111769
Experimental gerontology 2022 Jun 15;163:111769
METTL3 mediates osteoblast apoptosis by regulating endoplasmic reticulum stress during LPS-induced inflammation.
Kong Y, Zhang Y, Cai Y, Li D, Yi B, Xu Q
Cellular signalling 2022 Jul;95:110335
Cellular signalling 2022 Jul;95:110335
PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.
Ma H, Qi G, Han F, Peng J, Yuan C, Kong B
Experimental & molecular medicine 2022 Jul;54(7):999-1010
Experimental & molecular medicine 2022 Jul;54(7):999-1010
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway.
Wu G, Xue P, Jin H, Zhang M, Gui C, Bao G, Xu G, Jiang J, Zhang J, Cui S, Cui Z, Sun Y
Molecular biology reports 2022 Jul;49(7):6459-6466
Molecular biology reports 2022 Jul;49(7):6459-6466
Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.
Li H, Wu R, Xi Y, Li H, Chang G, Sun F, Wei C, Jiao L, Wen X, Zhang G, Zaid A, Hao J
Cell biology international 2022 Jul;46(7):1098-1108
Cell biology international 2022 Jul;46(7):1098-1108
The involvement of TRPM2 on the MPP(+)-induced oxidative neurotoxicity and apoptosis in hippocampal neurons from neonatal mice: protective role of resveratrol.
Yildizhan K, Çinar R, Naziroğlu M
Neurological research 2022 Jul;44(7):636-644
Neurological research 2022 Jul;44(7):636-644
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Li Y, Yang J, Zhang Q, Xu S, Sun W, Ge S, Xu X, Jager MJ, Jia R, Zhang J, Fan X
Oncogene 2022 Jul;41(27):3539-3553
Oncogene 2022 Jul;41(27):3539-3553
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Wang J, Wang Q, Chen P, Li Q, Li Z, Xu M, Zeng K, Li C
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Melatonin improves bisphenol A-induced cell apoptosis, oxidative stress and autophagy impairment via inhibition of the p38 MAPK signaling pathway in FLK-BLV cells.
Song D, Liu Y, Yao Y, Liu F, Tao W, Zhou X, Li R, Zhang X, Li X
Environmental toxicology 2022 Jul;37(7):1551-1562
Environmental toxicology 2022 Jul;37(7):1551-1562
MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13.
Zhang Z, Deng K, Kang Z, Wang F, Fan Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22370
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22370
SERPINA1 is a hub gene associated with intervertebral disc degeneration grade and affects the nucleus pulposus cell phenotype through the ADIRF-AS1/miR-214-3p axis.
Zhong H, Zhou Z, Guo L, Liu FS, Wang X, Li J, Lv GH, Zou MX
Translational research : the journal of laboratory and clinical medicine 2022 Jul;245:99-116
Translational research : the journal of laboratory and clinical medicine 2022 Jul;245:99-116
Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis.
Sun X, Zhong X, Ma W, Feng W, Huang Q, Ma M, Lv M, Hu R, Han Z, Li J, Zhou X
Experimental and therapeutic medicine 2022 Jul;24(1):456
Experimental and therapeutic medicine 2022 Jul;24(1):456
Targeted metabolomics analysis of bile acids and cell biology studies reveal the critical role of glycodeoxycholic acid in buffalo follicular atresia.
Wei Y, Cheng J, Luo M, Yang S, Xing Q, Cheng J, Lv J, Yu C, Sun L, Shi D, Deng Y
The Journal of steroid biochemistry and molecular biology 2022 Jul;221:106115
The Journal of steroid biochemistry and molecular biology 2022 Jul;221:106115
TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy.
Tian W, Liu SY, Zhang M, Meng JR, Tang N, Feng YD, Sun Y, Gao YY, Zhou L, Cao W, Li XQ
Pharmacological research 2022 Jul;181:106262
Pharmacological research 2022 Jul;181:106262
Baicalin Induced Apoptosis of Human Cholangiocarcinoma Cell through Activating AMPK/mTORC1/p70S6K Signaling Pathway.
Jia M, Yang F, Xu Y, Xu Q, Zeng Y, Dai R, Xiang Y
Bulletin of experimental biology and medicine 2022 Jul;173(3):366-370
Bulletin of experimental biology and medicine 2022 Jul;173(3):366-370
A New Berberine Preparation Protects Pancreatic Islet Cells from Apoptosis Mediated by Inhibition of Phospholipase A(2)/p38 MAPK Pathway.
Bi XJ, Lv YQ, Yang XH, Ge Y, Han H, Feng JS, Zhang M, Chen L, Xu MZ, Guan FY
Bulletin of experimental biology and medicine 2022 Jul;173(3):346-353
Bulletin of experimental biology and medicine 2022 Jul;173(3):346-353
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Cao J, Ma X, Liu L, Zhang G, Wu Y, Fu Y, Gong A, Yang Z, Zhao Y, Zhang L, Li Y
Annals of the New York Academy of Sciences 2022 Jul;1513(1):140-152
Annals of the New York Academy of Sciences 2022 Jul;1513(1):140-152
Endurance exercise-mediated metabolic reshuffle attenuates high-caloric diet-induced non-alcoholic fatty liver disease.
Cook JJ, Wei M, Segovia B, Cosio-Lima L, Simpson J, Taylor S, Koh Y, Kim S, Lee Y
Annals of hepatology 2022 Jul-Aug;27(4):100709
Annals of hepatology 2022 Jul-Aug;27(4):100709
sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death.
Wu Z, Xu Z, Zhou X, Li H, Zhao L, Lv Y, Guo Y, Shen G, He Y, Lei P
Cell death & disease 2022 Jul 7;13(7):587
Cell death & disease 2022 Jul 7;13(7):587
Sulforaphane Acts Through NFE2L2 to Prevent Hypoxia-Induced Apoptosis in Porcine Granulosa Cells via Activating Antioxidant Defenses and Mitophagy.
Zhang X, Chen Y, Li H, Chen B, Liu Z, Wu G, Li C, Li R, Cao Y, Zhou J, Shen M, Liu H, Tao J
Journal of agricultural and food chemistry 2022 Jul 6;70(26):8097-8110
Journal of agricultural and food chemistry 2022 Jul 6;70(26):8097-8110
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
Wang P, Liu D, Yan S, Liang Y, Cui J, Guo L, Ren S, Chen P
Toxics 2022 Jul 29;10(8)
Toxics 2022 Jul 29;10(8)
T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells.
Sun T, Zhang Q, Li M, Tang S, Dai C
Journal of fungi (Basel, Switzerland) 2022 Jul 22;8(8)
Journal of fungi (Basel, Switzerland) 2022 Jul 22;8(8)
PM2.5 promotes NSCLC carcinogenesis through translationally and transcriptionally activating DLAT-mediated glycolysis reprograming.
Chen Q, Wang Y, Yang L, Sun L, Wen Y, Huang Y, Gao K, Yang W, Bai F, Ling L, Zhou Z, Zhang X, Xiong J, Zhai R
Journal of experimental & clinical cancer research : CR 2022 Jul 22;41(1):229
Journal of experimental & clinical cancer research : CR 2022 Jul 22;41(1):229
Exposure to Bisphenol A Caused Hepatoxicity and Intestinal Flora Disorder in Rats.
Liu R, Liu B, Tian L, Jiang X, Li X, Cai D, Sun J, Bai W, Jin Y
International journal of molecular sciences 2022 Jul 21;23(14)
International journal of molecular sciences 2022 Jul 21;23(14)
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Xu Y, Wang X, Han D, Wang J, Luo Z, Jin T, Shi C, Zhou X, Lin L, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
P2X7R/NLRP3 signaling pathway-mediated pyroptosis and neuroinflammation contributed to cognitive impairment in a mouse model of migraine.
Wang Y, Shan Z, Zhang L, Fan S, Zhou Y, Hu L, Wang Y, Li W, Xiao Z
The journal of headache and pain 2022 Jul 2;23(1):75
The journal of headache and pain 2022 Jul 2;23(1):75
Melatonin Alleviates Hyperglycemia-Induced Cardiomyocyte Apoptosis via Regulation of Long Non-Coding RNA H19/miR-29c/MAPK Axis in Diabetic Cardiomyopathy.
Tang H, Zhong H, Liu W, Wang Y, Wang Y, Wang L, Tang S, Zhu H
Pharmaceuticals (Basel, Switzerland) 2022 Jul 2;15(7)
Pharmaceuticals (Basel, Switzerland) 2022 Jul 2;15(7)
Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN.
Liang W, Chen Y, Liu H, Zhao H, Luo T, Tang H, Zhou X, Jiang E, Shao Z, Liu K, Shang Z
International journal of oral science 2022 Jul 19;14(1):36
International journal of oral science 2022 Jul 19;14(1):36
Diffractaic acid, a novel TrxR1 inhibitor, induces cytotoxicity, apoptosis, and antimigration in human breast cancer cells.
Kalın ŞN, Altay A, Budak H
Chemico-biological interactions 2022 Jul 1;361:109984
Chemico-biological interactions 2022 Jul 1;361:109984
Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.
Wang Z, Liu D, Yan Q, Liu F, Zhan M, Qi S, Fang Q, Yao L, Wang W, Zhang R, Du J, Chen L
Transplantation 2022 Jul 1;106(7):1351-1364
Transplantation 2022 Jul 1;106(7):1351-1364
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Yu G, Ji S, Yun Y, Cheng K, Zhang H, Jia P, Wang T, Zhang L
Journal of animal science 2022 Jul 1;100(7)
Journal of animal science 2022 Jul 1;100(7)
Chlorogenic acid suppresses mitochondrial apoptotic effectors Bax/Bak to counteract Nod-like receptor pyrin domain 3 (NLRP3) inflammasome in thiram exposed chondrocytes.
Fakhar-E-Alam Kulyar M, Yao W, Ding Y, Du H, Mo Q, Pan H, Shahzad M, Mehmood K, Iqbal M, Akhtar M, Waqas M, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153865
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153865
Circular RNA circUSP13 sponges miR-29c to promote differentiation and inhibit apoptosis of goat myoblasts by targeting IGF1.
Zhang Z, Fan Y, Deng K, Liang Y, Zhang G, Gao X, El-Samahy MA, Zhang Y, Deng M, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22097
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22097
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H(2) S pathway in diabetic mice.
Wen X, Xi Y, Zhang Y, Jiao L, Shi S, Bai S, Sun F, Chang G, Wu R, Hao J, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22070
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22070
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise.
Yi T, Chen H, Zhan J, Li Y, Long Z, Wu Z, Yang M, Peng T, Li H
Experimental biology and medicine (Maywood, N.J.) 2022 Jan;247(2):165-173
Experimental biology and medicine (Maywood, N.J.) 2022 Jan;247(2):165-173
Thyroid stimulating hormone aggravates diabetic retinopathy through the mitochondrial apoptotic pathway.
Lin D, Qin R, Guo L
Journal of cellular physiology 2022 Jan;237(1):868-880
Journal of cellular physiology 2022 Jan;237(1):868-880
Molecular Mechanism of Aluminum-Induced Oxidative Damage and Apoptosis in Rat Cardiomyocytes.
Zhou L, He M, Li X, Lin E, Wang Y, Wei H, Wei X
Biological trace element research 2022 Jan;200(1):308-317
Biological trace element research 2022 Jan;200(1):308-317
Cytotoxic new caged-polyprenylated xanthonoids from Garcinia oligantha.
Liu Q, Zheng H, Wang X, Zhou L, Wang S, Shen T, Ren D
Fitoterapia 2022 Jan;156:105092
Fitoterapia 2022 Jan;156:105092
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Nie BX, Zhao G, Yuan XF, Yu LX, Zhang J, Yuan Y, Liu Y, Hu J, Song E, Zhou YC, Shu J
Journal of chemical neuroanatomy 2022 Jan;119:102053
Journal of chemical neuroanatomy 2022 Jan;119:102053
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Zhang B, Zhu Z, Zhang X, Li F, Ding A
Translational andrology and urology 2022 Jan;11(1):53-66
Translational andrology and urology 2022 Jan;11(1):53-66
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Du P, Zhang X, Luo K, Li Y, Fu C, Xiao J, Xiao Q
Human & experimental toxicology 2022 Jan-Dec;41:9603271221087146
Human & experimental toxicology 2022 Jan-Dec;41:9603271221087146
Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines.
Lee CW, Huang CC, Chi MC, Lee KH, Peng KT, Fang ML, Chiang YC, Liu JF
Molecules (Basel, Switzerland) 2022 Jan 7;27(2)
Molecules (Basel, Switzerland) 2022 Jan 7;27(2)
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
Zheng LY, Zou X, Wang YL, Zou M, Ma F, Wang N, Li JW, Wang MS, Hung HY, Wang Q
European journal of pharmacology 2022 Jan 5;914:174686
European journal of pharmacology 2022 Jan 5;914:174686
lncRNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5.
Jiang Y, Guo H, Tong T, Xie F, Qin X, Wang X, Chen W, Zhang J
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Jan 5;30(1):448-467
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Jan 5;30(1):448-467
lncRNA-encoded pep-AP attenuates the pentose phosphate pathway and sensitizes colorectal cancer cells to Oxaliplatin.
Wang X, Zhang H, Yin S, Yang Y, Yang H, Yang J, Zhou Z, Li S, Ying G, Ba Y
EMBO reports 2022 Jan 5;23(1):e53140
EMBO reports 2022 Jan 5;23(1):e53140
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Yang L, Wang Q, Zhao Q, Yang F, Liu T, Huang X, Yan Q, Yang X
Aging 2022 Jan 4;14(1):316-329
Aging 2022 Jan 4;14(1):316-329
Involvement of caspase in patulin-induced hepatotoxicity in vitro and in vivo.
Zhang B, Huang C, Lu Q, Liang H, Li J, Xu D
Toxicon : official journal of the International Society on Toxinology 2022 Jan 30;206:64-73
Toxicon : official journal of the International Society on Toxinology 2022 Jan 30;206:64-73
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma.
Li Y, Wang Y, Gao L, Tan Y, Cai J, Ye Z, Chen AT, Xu Y, Zhao L, Tong S, Sun Q, Liu B, Zhang S, Tian D, Deng G, Zhou J, Chen Q
Journal of nanobiotechnology 2022 Jan 21;20(1):39
Journal of nanobiotechnology 2022 Jan 21;20(1):39
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Li W, Huang BS, Xiong YY, Yang LJ, Wu LX
Cancer cell international 2022 Jan 18;22(1):32
Cancer cell international 2022 Jan 18;22(1):32
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Zhang Y, Han X, Tang Y, Zhang J, Hu Z, Xu W, Yao P, Niu Q
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice.
Li L, Zhang H, Chen B, Xia B, Zhu R, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Orekhov AN, Prentki M, Wang L, Guo S, Zhang D
Journal of ethnopharmacology 2022 Jan 10;282:114653
Journal of ethnopharmacology 2022 Jan 10;282:114653
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Shen Y, Yang F, Peng H, Zhang G, Zhu F, Xu H, Shi L
Journal of ethnopharmacology 2022 Jan 10;282:114601
Journal of ethnopharmacology 2022 Jan 10;282:114601
The Role of RAD6B and PEDF in Retinal Degeneration.
Ye Q, Wang J, Liu X, Liu Z, BaZong L, Ma J, Shen R, Ye W, Zhang W, Wang D
Neuroscience 2022 Jan 1;480:19-31
Neuroscience 2022 Jan 1;480:19-31
Neuroprotective Effects of Tetrahydroxystilbene Glucoside against Rotenone-Induced Toxicity in PC12 Cells.
Fu R, Xing H, Wang X, Liu Y, Li B, Zhang L, Li Z, Duan D, Chen J
Biological & pharmaceutical bulletin 2022 Jan 1;45(1):143-149
Biological & pharmaceutical bulletin 2022 Jan 1;45(1):143-149
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
Kan Y, Song M, Cui X, Yang Q, Zang Y, Li Q, Li Y, Cai W, Chen Y, Weng X, Wang Y, Zhu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153834
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153834
Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.
Wang Y, Wang J, Hao Z, Yang H, Li Y, Tan M, Liu L, Feng S, Mei L, Qian B
Andrologia 2022 Feb;54(1):e14287
Andrologia 2022 Feb;54(1):e14287
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenvironment.
Xu M, Luo LL, Du MY, Tang L, Zhou J, Hu Y, Mei H
Current medical science 2022 Feb;42(1):26-38
Current medical science 2022 Feb;42(1):26-38
Estrogen receptor-α36 is involved in diallyl sulfide-induced inhibition of malignant growth of HepG2 and Huh7 hepatocellular carcinoma cells.
Wu W, Chen H, Wang R, Chen J, Yu H, Wei Z, Liu X, Xue M, Chen Q, Zhou H, Fu Z
Environmental toxicology 2022 Feb;37(2):270-281
Environmental toxicology 2022 Feb;37(2):270-281
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Hu JH, Fan P, Zhang LR, Chen CY, Xu J, Huang J, Lu WT, Zhu SJ, Qiu GP, Xu SY, Ran JH, Gan SW
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Wang N, Huang R, Yang K, He Y, Gao Y, Dong D
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
Li T, Huang S, Yan W, Zhang Y, Guo Q
Experimental and therapeutic medicine 2022 Feb;23(2):169
Experimental and therapeutic medicine 2022 Feb;23(2):169
Cardiotoxicity of patulin was found in H9c2 cells.
Zhang B, Liang H, Huang K, Li J, Xu D, Huang C, Li Y
Toxicon : official journal of the International Society on Toxinology 2022 Feb;207:21-30
Toxicon : official journal of the International Society on Toxinology 2022 Feb;207:21-30
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Huang Z, Dai H, Jiang J, Ye N, Zhu S, Wei Q, Lv Z, Shi F
Theriogenology 2022 Feb;179:177-186
Theriogenology 2022 Feb;179:177-186
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.
Wang G, Wu HL, Liu YP, Yan DQ, Yuan ZL, Chen L, Yang Q, Gao YS, Diao B
Neural regeneration research 2022 Feb;17(2):354-361
Neural regeneration research 2022 Feb;17(2):354-361
Anticancer effects of myricetin derivatives in non-small cell lung cancer in vitro and in vivo.
Li M, Zha G, Chen R, Chen X, Sun Q, Jiang H
Pharmacology research & perspectives 2022 Feb;10(1):e00905
Pharmacology research & perspectives 2022 Feb;10(1):e00905
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Lu T, Li H, Zhou Y, Wei W, Ding L, Zhan Z, Liu W, Tao J, Xue X
Journal of neuroinflammation 2022 Feb 7;19(1):37
Journal of neuroinflammation 2022 Feb 7;19(1):37
Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury through the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression.
Liu XM, Zhang Z, Zhong J, Li N, Wang T, Wang L, Zhang Q
European journal of pharmacology 2022 Feb 5;916:174719
European journal of pharmacology 2022 Feb 5;916:174719
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Liang JJ, Yu WL, Yang L, Xie BH, Qin KM, Yin YP, Yan JJ, Gong S, Liu TY, Zhou HB, Hong K
European journal of medicinal chemistry 2022 Feb 5;229:114081
European journal of medicinal chemistry 2022 Feb 5;229:114081
Asparaginyl endopeptidase protects against podocyte injury in diabetic nephropathy through cleaving cofilin-1.
Lei C, Li M, Qiu Y, Xie Y, Hao Z, Yin X, Zhang Z, Su H, Yang L, Lin J, Hammes HP, Zhang C
Cell death & disease 2022 Feb 25;13(2):184
Cell death & disease 2022 Feb 25;13(2):184
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162
Cell death & disease 2022 Feb 18;13(2):162
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
Huang Y, Chen S, Pang L, Feng Z, Su H, Zhu W, Wei J
European journal of pharmacology 2022 Feb 15;917:174749
European journal of pharmacology 2022 Feb 15;917:174749
Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders.
Zhao T, Tang X, Li D, Zhao J, Zhou R, Shu F, Jia W, Fu W, Xia H, Liu G
Journal of hazardous materials 2022 Feb 15;424(Pt B):127547
Journal of hazardous materials 2022 Feb 15;424(Pt B):127547
Knocking Down Peroxiredoxin 6 Aggravates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitophagy.
Hong T, Zhou Y, Peng L, Wu X, Li Y, Li Y, Zhao Y
Neuroscience 2022 Feb 1;482:30-42
Neuroscience 2022 Feb 1;482:30-42
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Han QJ, Han G, Peng J, Tang Z
Free radical biology & medicine 2022 Feb 1;179:416-417
Free radical biology & medicine 2022 Feb 1;179:416-417
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Lv S, Zhang W, Yuan P, Lu C, Dong J, Zhang J
Pharmaceutical biology 2022 Dec;60(1):722-728
Pharmaceutical biology 2022 Dec;60(1):722-728
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
Jiao Y, Xin M, Xu J, Xiang X, Li X, Jiang J, Jia X
Pharmaceutical biology 2022 Dec;60(1):1781-1789
Pharmaceutical biology 2022 Dec;60(1):1781-1789
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Yang Y, Ren ZZ, Wei WJ, He ZL, Deng YL, Wang Z, Fan YC, Zhou J, Jiang LH
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Pharmaceutical biology 2022 Dec;60(1):1566-1577
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation.
Dong Y, Zhang Y, Wang X, Li W, Zhang J, Lu L, Dong H, Fan S, Meng A, Li D
Animal models and experimental medicine 2022 Dec;5(6):565-574
Animal models and experimental medicine 2022 Dec;5(6):565-574
A metabolomic approach to study triptolide-induced ovarian damage in rats.
Zhou F, Zhong LL, Tan Y, Liu L, Pei G
Toxicology 2022 Dec;482:153351
Toxicology 2022 Dec;482:153351
Caveolin-1 suppresses hippocampal neuron apoptosis via the regulation of HIF1α in hypoxia in naked mole-rats.
Yang W, Wu W, Zhao Y, Li Y, Zhang C, Zhang J, Chen C, Cui S
Cell biology international 2022 Dec;46(12):2060-2074
Cell biology international 2022 Dec;46(12):2060-2074
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
Enhancement of the cytotoxic effect of dihydroartemisinin in high-risk human papillomavirus-infected cells by aminolevulinic acid via the Bax/Bcl-2-caspase pathway.
Che Q, Wang Q, Lu H, Li C, Zeng K
Photodiagnosis and photodynamic therapy 2022 Dec;40:103053
Photodiagnosis and photodynamic therapy 2022 Dec;40:103053
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Li F, Mao Q, Wang J, Zhang X, Lv X, Wu B, Yan T, Jia Y
Metabolic brain disease 2022 Dec;37(8):2965-2978
Metabolic brain disease 2022 Dec;37(8):2965-2978
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Yao J, Wu J, Jia S, Shao J, Zhang X, Xu Z, Zhang H, Li H, Yao X
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Zhou X, Song L, Cong R, Luan J, Zhou X, Wang Y, Yao L, Zhang X, Ren X, Zhang T, Yu M, Song N
Chemosphere 2022 Dec;308(Pt 3):136486
Chemosphere 2022 Dec;308(Pt 3):136486
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Jin X, Li X, Li L, Zhong B, Hong Y, Niu J, Li B
The Journal of biological chemistry 2022 Dec;298(12):102587
The Journal of biological chemistry 2022 Dec;298(12):102587
Bone-targeted nanoplatform enables efficient modulation of bone tumor microenvironment for prostate cancer bone metastasis treatment.
Zhang X, Liu Q, Zhang T, Gao P, Wang H, Yao L, Huang J, Jiang S
Drug delivery 2022 Dec;29(1):889-905
Drug delivery 2022 Dec;29(1):889-905
Alfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway.
Cui Y, Li F, Zhu X, Xu J, Muhammad A, Chen Y, Li D, Liu B, Wang C, Wang Z, Ma S, Liu X, Shi Y
Redox report : communications in free radical research 2022 Dec;27(1):1-8
Redox report : communications in free radical research 2022 Dec;27(1):1-8
Nickel nanoparticles exert cytotoxic effects on trophoblast HTR-8/SVneo cells possibly via Nrf2/MAPK/caspase 3 pathway.
Li T, Li Z, Fu J, Tang C, Liu L, Xu J, Zhao J, Li Z
Environmental research 2022 Dec;215(Pt 2):114336
Environmental research 2022 Dec;215(Pt 2):114336
Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats.
Chen Q, Lin J, Deng Z, Qian W
Regenerative therapy 2022 Dec;21:216-224
Regenerative therapy 2022 Dec;21:216-224
GRN-/- iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis.
Bossolasco P, Cimini S, Maderna E, Bardelli D, Canafoglia L, Cavallaro T, Ricci M, Silani V, Marucci G, Rossi G
Neurobiology of disease 2022 Dec;175:105891
Neurobiology of disease 2022 Dec;175:105891
Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.
Varier KM, Dan G, Liu W, Wu G, Xiao C, Lei H, Ling T, Jiang Y, Chen Y, Ben-David Y, Li Y, Zhang N, Gajendran B, Shen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113887
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113887
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Jie W, Rui-Fen Z, Zhong-Xiang H, Yan W, Wei-Na L, Yong-Ping M, Jing S, Jing-Yi C, Wan-Hong L, Xiao-Hua H, Zhi L, Yan S
Virulence 2022 Dec;13(1):342-354
Virulence 2022 Dec;13(1):342-354
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Sun S, Yin Q, Li B, Deng Y, Li J, Xiong Y, Shaojun H
Journal of thermal biology 2022 Dec;110:103348
Journal of thermal biology 2022 Dec;110:103348
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Wang H, Yao J, Chen Y, Wang Y, Liu Y, Liao Y, Liang Z, Dong YH, Qu M, Ge X, Zhou X
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Hao J, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Wei C, Li H
Cellular signalling 2022 Dec;100:110465
Cellular signalling 2022 Dec;100:110465
Idebenone reduces sepsis-induced oxidative stress and apoptosis in hepatocytes via RAGE/p38 signaling.
Gou T, Jin X, Xia J
Annals of translational medicine 2022 Dec;10(24):1363
Annals of translational medicine 2022 Dec;10(24):1363
Elsholtzia bodinieri Vaniot Ameliorated Acute Lung Injury by NQO1, BCL2 and PTGS2 In Silico and In Vitro Analyses.
Sun J, Jiang X, Chen Y, Guo S, Zhao Z, Cao J, Liu Y, Cheng G, Li Y, Tian L
International journal of molecular sciences 2022 Dec 9;23(24)
International journal of molecular sciences 2022 Dec 9;23(24)
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
Huang X, Yan Y, Gui A, Zhu S, Qiu S, Chen F, Liu W, Zuo J, Yang L
International journal of molecular sciences 2022 Dec 4;23(23)
International journal of molecular sciences 2022 Dec 4;23(23)
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Wang Y, Lei J, Zhang S, Wang X, Jin J, Liu Y, Gan M, Yuan Y, Sun L, Li X, Han T, Wang JB
Cell death & disease 2022 Dec 27;13(12):1075
Cell death & disease 2022 Dec 27;13(12):1075
Multi-specific niflumic acid platinum(IV) complexes displaying potent antitumor activities by improving immunity and suppressing angiogenesis besides causing DNA damage.
Li L, Zhang M, Jia D, Liu Z, Zhang N, Sun B, Wang Z, Liu M, Wang Q
Dalton transactions (Cambridge, England : 2003) 2022 Dec 20;52(1):147-158
Dalton transactions (Cambridge, England : 2003) 2022 Dec 20;52(1):147-158
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Yang W, Guo C, Herman JG, Zhu C, Lv H, Su X, Zhang L, Zhang M, Guo M
Clinical epigenetics 2022 Dec 2;14(1):164
Clinical epigenetics 2022 Dec 2;14(1):164
Synergistic Effects of the Combinational Use of Escitalopram Oxalate and 5-Fluorouracil on the Inhibition of Gastric Cancer SNU-1 Cells.
Chen VC, Huang JY, Tzang BS, Hsu TC, McIntyre RS
International journal of molecular sciences 2022 Dec 19;23(24)
International journal of molecular sciences 2022 Dec 19;23(24)
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Dai Z, Liu X, Zeng H, Chen Y
Respiratory research 2022 Dec 17;23(1):356
Respiratory research 2022 Dec 17;23(1):356
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
Ye H, Ma Z, Liu L, Zhang T, Han Q, Xiang Z, Xia Y, Ke Y, Guan X, Shi Q, Ataullakhanov FI, Panteleev M
ChemMedChem 2022 Dec 16;17(24):e202200317
ChemMedChem 2022 Dec 16;17(24):e202200317
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
Zhang Y, Xu T, Tian H, Wu J, Yu X, Zeng L, Liu F, Liu Q, Huang X
Cancers 2022 Dec 15;14(24)
Cancers 2022 Dec 15;14(24)
HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death.
Saro A, Gao Z, Kambey PA, Li M, Huang J
Viruses 2022 Dec 15;14(12)
Viruses 2022 Dec 15;14(12)
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
Xie T, Yang R, Zhang X, Shen X, Yu L, Liao J, Bao T, Fang Q
The Tohoku journal of experimental medicine 2022 Dec 14;259(1):49-55
The Tohoku journal of experimental medicine 2022 Dec 14;259(1):49-55
Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts.
Li S, Yang J, Sun J, Chen M
Cells 2022 Dec 12;11(24)
Cells 2022 Dec 12;11(24)
Totipotency of miR-184 in porcine granulosa cells.
Shi S, Hu Y, Song X, Huang L, Zhang L, Zhou X, Gao L, Pang W, Yang G, Chu G
Molecular and cellular endocrinology 2022 Dec 1;558:111765
Molecular and cellular endocrinology 2022 Dec 1;558:111765
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Xue Y, Luo M, Hu X, Li X, Shen J, Zhu W, Huang L, Hu Y, Guo Y, Liu L, Wang L, Luo S
Communications biology 2022 Dec 1;5(1):1316
Communications biology 2022 Dec 1;5(1):1316
Thiram induces myocardial oxidative damage and apoptosis in broilers via interfering their cardiac metabolism.
Mo Q, Kulyar MF, Ding Y, Zhang Y, Pan H, Li J
Ecotoxicology and environmental safety 2022 Dec 1;247:114225
Ecotoxicology and environmental safety 2022 Dec 1;247:114225
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Li J, Bu Y, Li B, Zhang H, Guo J, Hu J, Zhang Y
Journal of molecular histology 2022 Aug;53(4):713-727
Journal of molecular histology 2022 Aug;53(4):713-727
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Chen S, Huang Y, Su H, Zhu W, Wei Y, Long Y, Shi Y, Wei J
Inflammation 2022 Aug;45(4):1780-1799
Inflammation 2022 Aug;45(4):1780-1799
Protective role of selenium on MPP(+) and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells.
Yıldızhan K, Nazıroğlu M
Journal of receptor and signal transduction research 2022 Aug;42(4):399-408
Journal of receptor and signal transduction research 2022 Aug;42(4):399-408
DDX3X alleviates doxorubicin-induced cardiotoxicity by regulating Wnt/β-catenin signaling pathway in an in vitro model.
Feng D, Li J, Guo L, Liu J, Wang S, Ma X, Song Y, Liu J, Hao E
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23077
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23077
MiR-383-5p promotes apoptosis of ovarian granulosa cells by targeting CIRP through the PI3K/AKT signaling pathway.
Li Y, Wu X, Miao S, Cao Q
Archives of gynecology and obstetrics 2022 Aug;306(2):501-512
Archives of gynecology and obstetrics 2022 Aug;306(2):501-512
Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells.
Jiang Q, Di Q, Shan D, Xu Q
Ecotoxicology and environmental safety 2022 Aug;241:113822
Ecotoxicology and environmental safety 2022 Aug;241:113822
Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
Wei W, Li Y, Wang C, Gao S, Zhao Y, Yang Z, Wang H, Gao Z, Jiang Y, He Y, Zhao L, Gao H, Yao X, Hu Y
Pharmacological research 2022 Aug;182:106285
Pharmacological research 2022 Aug;182:106285
The miR-410-5p /ITGA6 axis participates in the pathogenesis of recurrent abortion by regulating the biological function of trophoblast.
Wu S, Liu H, Zhou M, Shang Y, Luo L, Chen J, Yang J
Journal of reproductive immunology 2022 Aug;152:103647
Journal of reproductive immunology 2022 Aug;152:103647
GFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation.
Wei S, Zhao Q, Zheng K, Liu P, Sha N, Li Y, Ma C, Li J, Zhuo L, Liu G, Liang W, Jiang Y, Chen T, Zhong N
Cell discovery 2022 Aug 9;8(1):77
Cell discovery 2022 Aug 9;8(1):77
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
Wang C, Chen X, Liu X, Lu D, Li S, Qu L, Yin F, Luo H, Zhang Y, Luo Z, Cui N, Kong L, Wang X
European journal of medicinal chemistry 2022 Aug 5;238:114462
European journal of medicinal chemistry 2022 Aug 5;238:114462
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Sokouti H, Mohajeri D, Nourazar MA
Physiological research 2022 Aug 31;71(4):551-560
Physiological research 2022 Aug 31;71(4):551-560
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Jia X, Xin M, Xu J, Xiang X, Li X, Jiao Y, Wang L, Jiang J, Pang F, Zhang X, Zhang J
Cell death & disease 2022 Aug 30;13(8):750
Cell death & disease 2022 Aug 30;13(8):750
Notoginsenoside R1 alleviates spinal cord injury by inhibiting oxidative stress, neuronal apoptosis, and inflammation via activating the nuclear factor erythroid 2 related factor 2/heme oxygenase-1 signaling pathway.
Luo H, Bao Z, Zhou M, Chen Y, Huang Z
Neuroreport 2022 Aug 3;33(11):451-462
Neuroreport 2022 Aug 3;33(11):451-462
Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy.
Wang N, Li Y, He F, Liu S, Liu Y, Peng J, Liu J, Yu C, Wang S
Pharmaceuticals (Basel, Switzerland) 2022 Aug 29;15(9)
Pharmaceuticals (Basel, Switzerland) 2022 Aug 29;15(9)
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
Yan Y, Huang J, Huan C, Li L, Li C
Metabolites 2022 Aug 27;12(9)
Metabolites 2022 Aug 27;12(9)
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Liu M, Yue Z, Zhang B, Li F, Liu L, Li F
Metabolites 2022 Aug 25;12(9)
Metabolites 2022 Aug 25;12(9)
Development of a series of flurbiprofen and zaltoprofen platinum(IV) complexes with anti-metastasis competence targeting COX-2, PD-L1 and DNA.
Li Z, Li L, Zhao W, Sun B, Liu Z, Liu M, Han J, Wang Z, Li D, Wang Q
Dalton transactions (Cambridge, England : 2003) 2022 Aug 23;51(33):12604-12619
Dalton transactions (Cambridge, England : 2003) 2022 Aug 23;51(33):12604-12619
Chiral FA Conjugated CdTe/CdS Quantum Dots for Selective Cancer Ablation.
Li G, Zhang X, Fei X, Li J, Liu H, Liu W, Yang Y, Li B, Liu M, Yang G, Zhang T
ACS nano 2022 Aug 23;16(8):12991-13001
ACS nano 2022 Aug 23;16(8):12991-13001
Investigation of the effects of high cervical spinal cord electrical stimulation on improving neurological dysfunction and its potential mechanism in rats with traumatic brain injury.
Zhao PC, Huang ZS, Xu SN, Deng PC, Qian F, Shi J, Zhang YM
Neuroreport 2022 Aug 2;33(12):509-517
Neuroreport 2022 Aug 2;33(12):509-517
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI.
Yang R, Yang H, Li W, Yue F, Chen H, Hao Y, Hu K
The Journal of pharmacy and pharmacology 2022 Aug 19;74(8):1117-1124
The Journal of pharmacy and pharmacology 2022 Aug 19;74(8):1117-1124
METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner.
Li J, Yao H, Huang J, Li C, Zhang Y, Xu R, Wang Z, Long Z, Tang J, Wang L
Cell death & disease 2022 Aug 19;13(8):723
Cell death & disease 2022 Aug 19;13(8):723
Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy.
Sun Y, Guan X, Zhang T, Li Y, Shi H, Chitakunye AT, Hong H, Zhang S, Zhu Q, Cai L
Medical oncology (Northwood, London, England) 2022 Aug 16;39(11):159
Medical oncology (Northwood, London, England) 2022 Aug 16;39(11):159
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Liu J, Li B, Liu J, Qiu F, Diao Y, Lei Y, Liu J, Zhang W
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)
Exosomal circ-CACNG2 promotes cardiomyocyte apoptosis in multiple myeloma via modulating miR-197-3p/caspase3 axis.
Yu M, Ji L, Li S, Zhang Y, Sun X, Sun R, Chen X, Luo Y, Cui X
Experimental cell research 2022 Aug 15;417(2):113229
Experimental cell research 2022 Aug 15;417(2):113229
Investigation and experimental validation of curcumin-related mechanisms against hepatocellular carcinoma based on network pharmacology.
Chen Y, Li Q, Ren S, Chen T, Zhai B, Cheng J, Shi X, Song L, Fan Y, Guo D
Journal of Zhejiang University. Science. B 2022 Aug 15;23(8):682-698
Journal of Zhejiang University. Science. B 2022 Aug 15;23(8):682-698
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Dong Y, Yu H, Li X, Bian K, Zheng Y, Dai M, Feng X, Sun Y, He Y, Yu B, Zhang H, Wu J, Yu X, Wu H, Kong W
Journal of neuroinflammation 2022 Aug 15;19(1):205
Journal of neuroinflammation 2022 Aug 15;19(1):205
Ginseng oligosaccharides protect neurons from glutamate-induced oxidative damage through the Nrf2/HO-1 signaling pathway.
Yan X, Chen X, Fu C, Jing C, Zhao D, Sun L
Food & function 2022 Aug 15;13(16):8605-8615
Food & function 2022 Aug 15;13(16):8605-8615
12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis.
Chen Q, Zheng Q, Yang Y, Luo Y, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Ma J, Tian X, Yang J
International journal of molecular sciences 2022 Aug 12;23(16)
International journal of molecular sciences 2022 Aug 12;23(16)
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264
Cellular signalling 2022 Apr;92:110264
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.
Guo X, Xu Y, Geng R, Qiu J, He X
Molecular nutrition & food research 2022 Apr;66(8):e2100943
Molecular nutrition & food research 2022 Apr;66(8):e2100943
GSK-126 Protects CA1 Neurons from H3K27me3-Mediated Apoptosis in Cerebral Ischemia.
Wang Z, Su Y, Zhang L, Lan T, Li L, Qi S
Molecular neurobiology 2022 Apr;59(4):2552-2562
Molecular neurobiology 2022 Apr;59(4):2552-2562
LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.
Kong X, Fei Q, Pan C, Jin J, Zheng J, Wu D, Li H, Huang X
In vitro cellular & developmental biology. Animal 2022 Apr;58(4):295-306
In vitro cellular & developmental biology. Animal 2022 Apr;58(4):295-306
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
He W, Zhou X, Wu Q, Zhou L, Zhang Z, Zhang R, Deng C, Zhang X
Journal of molecular histology 2022 Apr;53(2):511-521
Journal of molecular histology 2022 Apr;53(2):511-521
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Zeng L, He J, Liu C, Zhang F, Zhang Z, Chen H, Wang Q, Ding X, Luo H
Inflammation 2022 Apr;45(2):725-738
Inflammation 2022 Apr;45(2):725-738
Sevoflurane impairs m6A-mediated mRNA translation and leads to fine motor and cognitive deficits.
Zhang L, Cheng Y, Xue Z, Li J, Wu N, Yan J, Wang J, Wang C, Chen W, Zhou T, Qiu Z, Jiang H
Cell biology and toxicology 2022 Apr;38(2):347-369
Cell biology and toxicology 2022 Apr;38(2):347-369
Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κ B and PI3K/AKT Signaling In Vitro and In Vivo.
Xuan L, Hu JH, Bi R, Liu SQ, Wang CX
Chinese journal of integrative medicine 2022 Apr;28(4):349-356
Chinese journal of integrative medicine 2022 Apr;28(4):349-356
BMAL1 regulates mitochondrial homeostasis in renal ischaemia-reperfusion injury by mediating the SIRT1/PGC-1α axis.
Ye P, Li W, Huang X, Zhao S, Chen W, Xia Y, Yu W, Rao T, Ning J, Zhou X, Ruan Y, Cheng F
Journal of cellular and molecular medicine 2022 Apr;26(7):1994-2009
Journal of cellular and molecular medicine 2022 Apr;26(7):1994-2009
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer.
Yu TT, Peng XC, Wang MF, Han N, Xu HZ, Li QR, Li LG, Xu X, Ma QL, Liu B, Wang J, Zhao L, Chen X, Li TF
Journal of cancer research and clinical oncology 2022 Apr;148(4):867-879
Journal of cancer research and clinical oncology 2022 Apr;148(4):867-879
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Zhan L, Pu J, Zheng J, Hang S, Pang L, Dai M, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
The interferon regulatory factor 6 promotes cisplatin sensitivity in colorectal cancer.
Tan L, Qu W, Wu D, Liu M, Ai Q, Hu H, Wang Q, Chen W, Zhou H
Bioengineered 2022 Apr;13(4):10504-10517
Bioengineered 2022 Apr;13(4):10504-10517
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
Wu D, Yang C, Yang M, Wu Y, Mao Y, Zhou X, Wang J, Yuan Z, Wu J
Toxins 2022 Apr 6;14(4)
Toxins 2022 Apr 6;14(4)
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels.
Han Y, Li C, Zhang P, Yang X, Min J, Wu Q, Xie Y, Jin D, Wang Z, Shao F, Quan H
European journal of pharmacology 2022 Apr 5;920:174811
European journal of pharmacology 2022 Apr 5;920:174811
Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway.
Li J, Li B, Bu Y, Zhang H, Guo J, Hu J, Zhang Y
Molecules and cells 2022 Apr 30;45(4):216-230
Molecules and cells 2022 Apr 30;45(4):216-230
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Yu H, Li M, Wen X, Yang J, Liang X, Li X, Bao X, Shu J, Ren X, Chen W, Li Z, Li Y
Arthritis research & therapy 2022 Apr 29;24(1):93
Arthritis research & therapy 2022 Apr 29;24(1):93
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Dietary Tryptophan Supplementation Improves Antioxidant Status and Alleviates Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Pyroptosis in the Intestine of Piglets after Lipopolysaccharide Challenge.
Liu G, Tao J, Lu J, Jia G, Zhao H, Chen X, Tian G, Cai J, Zhang R, Wang J
Antioxidants (Basel, Switzerland) 2022 Apr 28;11(5)
Antioxidants (Basel, Switzerland) 2022 Apr 28;11(5)
Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia.
Jiang C, Qian M, Gocho Y, Yang W, Du G, Shen S, Yang JJ, Zhang H
Blood advances 2022 Apr 26;6(8):2496-2509
Blood advances 2022 Apr 26;6(8):2496-2509
Berberine alleviates LPS-induced apoptosis, oxidation, and skewed lineages during mouse preimplantation development†.
Miao X, Cui W
Biology of reproduction 2022 Apr 26;106(4):699-709
Biology of reproduction 2022 Apr 26;106(4):699-709
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Zhao N, Gui X, Fang Q, Zhang R, Zhu W, Zhang H, Li Q, Zhou Y, Zhao J, Cui X, Gao G, Tang H, Shen N, Chen T, Song H, Shen W
Journal of nanobiotechnology 2022 Apr 2;20(1):174
Journal of nanobiotechnology 2022 Apr 2;20(1):174
Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment.
Chen L, Chen Y, Ding W, Zhan T, Zhu J, Zhang L, Wang H, Shen B, Wang Y
Cells 2022 Apr 2;11(7)
Cells 2022 Apr 2;11(7)
Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.
Wu Z, Zhou G, Wang H, Yao P
International journal of molecular sciences 2022 Apr 18;23(8)
International journal of molecular sciences 2022 Apr 18;23(8)
Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells.
Chen L, Yan Y, Kong F, Wang J, Zeng J, Fang Z, Wang Z, Liu Z, Liu F
Cancers 2022 Apr 18;14(8)
Cancers 2022 Apr 18;14(8)
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Xiao W, Su J, Gao X, Yang H, Weng R, Ni W, Gu Y
Microbiome 2022 Apr 17;10(1):62
Microbiome 2022 Apr 17;10(1):62
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Fu NJ, Xi RY, Shi XK, Li RZ, Zhang ZH, Li LY, Zhang GL, Wang F
Toxicology and applied pharmacology 2022 Apr 15;441:115988
Toxicology and applied pharmacology 2022 Apr 15;441:115988
NaAsO(2) decreases GSH synthesis by inhibiting GCLC and induces apoptosis through Hela cell mitochondrial damage, mediating the activation of the NF-κB/miR-21 signaling pathway.
Ran S, Gao X, Ma M, Zhang J, Li S, Zhang M, Li S
Ecotoxicology and environmental safety 2022 Apr 1;234:113380
Ecotoxicology and environmental safety 2022 Apr 1;234:113380
PARP1 Inhibitor Combined With Oxaliplatin Efficiently Suppresses Oxaliplatin Resistance in Gastric Cancer-Derived Organoids via Homologous Recombination and the Base Excision Repair Pathway.
Li H, Wang C, Lan L, Wu W, Evans I, Ruiz EJ, Yan L, Zhou Z, Oliveira JM, Reis RL, Hu Z, Chen W, Behrens A, He Y, Zhang C
Frontiers in cell and developmental biology 2021;9:719192
Frontiers in cell and developmental biology 2021;9:719192
Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR.
Yang Y, Li J, Yao L, Wu L
Frontiers in cell and developmental biology 2021;9:710721
Frontiers in cell and developmental biology 2021;9:710721
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763
Frontiers in cell and developmental biology 2021;9:662763
Transcriptomic Data Analyses Reveal That Sow Fertility-Related lincRNA NORFA Is Essential for the Normal States and Functions of Granulosa Cells.
Du X, Li Q, Yang L, Zeng Q, Wang S, Li Q
Frontiers in cell and developmental biology 2021;9:610553
Frontiers in cell and developmental biology 2021;9:610553
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Ou G, Jiang X, Gao A, Li X, Lin Z, Pei S
Frontiers in veterinary science 2021;8:801407
Frontiers in veterinary science 2021;8:801407
Validated Impacts of N6-Methyladenosine Methylated mRNAs on Apoptosis and Angiogenesis in Myocardial Infarction Based on MeRIP-Seq Analysis.
Zhang Y, Hua W, Dang Y, Cheng Y, Wang J, Zhang X, Teng M, Wang S, Zhang M, Kong Z, Lu X, Zheng Y
Frontiers in molecular biosciences 2021;8:789923
Frontiers in molecular biosciences 2021;8:789923
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Wu X, Zhang T, Lyu P, Chen M, Ni G, Cheng H, Xu G, Li X, Wang L, Shang H
Frontiers in cardiovascular medicine 2021;8:698056
Frontiers in cardiovascular medicine 2021;8:698056
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Zhang XM, Gu YH, Deng H, Xu ZQ, Zhong ZY, Lyu XJ, Jin HM, Yang XH
Frontiers in cardiovascular medicine 2021;8:691336
Frontiers in cardiovascular medicine 2021;8:691336
Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Differentiation Under Cisplatin-Induced ROS Exposure.
Zhou L, Lu R, Huang C, Lin D
Frontiers in molecular biosciences 2021;8:685362
Frontiers in molecular biosciences 2021;8:685362
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Zhang P, Han X, Zhang X, Zhu X
Frontiers in nutrition 2021;8:667695
Frontiers in nutrition 2021;8:667695
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Pilose Antler Peptide-3.2KD Ameliorates Adriamycin-Induced Myocardial Injury Through TGF-β/SMAD Signaling Pathway.
Xu Y, Qu X, Zhou J, Lv G, Han D, Liu J, Liu Y, Chen Y, Qu P, Huang X
Frontiers in cardiovascular medicine 2021;8:659643
Frontiers in cardiovascular medicine 2021;8:659643
Quercetin Antagonizes Glucose Fluctuation Induced Renal Injury by Inhibiting Aerobic Glycolysis via HIF-1α/miR-210/ISCU/FeS Pathway.
Xu WL, Liu S, Li N, Ye LF, Zha M, Li CY, Zhao Y, Pu Q, Bao JJ, Chen XJ, Yu JY, Pei YH
Frontiers in medicine 2021;8:656086
Frontiers in medicine 2021;8:656086
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Li X, Gao M, Zhu S, Yin L, Zhang B, Qi Y, Zhao Y, Yu Y, Xu L
Frontiers in nutrition 2021;8:635232
Frontiers in nutrition 2021;8:635232
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Yao M, Zhang J, Li Z, Bai X, Ma J, Li Y
Frontiers in medicine 2021;8:630962
Frontiers in medicine 2021;8:630962
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Tai H, Jiang XL, Song N, Xiao HH, Li Y, Cheng MJ, Yin XM, Chen YR, Yang GL, Jiang XY, Kuang JS, Lan ZM, Jia LQ
Frontiers in medicine 2021;8:617393
Frontiers in medicine 2021;8:617393
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J
Nutrition and cancer 2021;73(8):1459-1470
Nutrition and cancer 2021;73(8):1459-1470
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Yang X, Jin J, Yang J, Zhou L, Mi S, Qi G
Genetics and molecular biology 2021;44(4):e20210058
Genetics and molecular biology 2021;44(4):e20210058
EphA2 overexpression reduces H2O2-induced damage of lens epithelial cells.
Ji Q, Liu J, Wang G, Liu L, Zhong J
Genetics and molecular biology 2021;44(3):e20200414
Genetics and molecular biology 2021;44(3):e20200414
Shen-fu injection alleviates acute renal injury by reducing cytokine levels and modulating apoptosis in a porcine hemorrhagic shock model.
Yuan W, Wu J, Zhang Q, Liang Y, Zhang M, Qin H, Li CS
Acta cirurgica brasileira 2021;36(4):e360405
Acta cirurgica brasileira 2021;36(4):e360405
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Li Y, Chandra TP, Song X, Nie L, Liu M, Yi J, Zheng X, Chu C, Yang J
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Erteng-Sanjie Capsule Enhances Chemosensitivity of 5-Fluorouracil in Tumor-Bearing Nude Mice with Gastric Cancer by Inhibiting Notch1/Hes1 Signaling Pathway.
Zhou J, Hao S, Guo H, Yu H, Guo Z, Liu L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9980565
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9980565
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Wang L, Li S, Qi L, Ling L
Mediators of inflammation 2021;2021:9978882
Mediators of inflammation 2021;2021:9978882
Huxie Huaji Ointment Induced Apoptosis of Liver Cancer Cells In Vivo and In Vitro by Activating the Mitochondrial Pathway.
Cai Y, Du Q, Deng TH, Shen BB, Peng YM, Zeng PH, Yu SR
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9922059
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9922059
Escin Sodium Improves the Prognosis of Acute Pancreatitis via Promoting Cell Apoptosis by Suppression of the ERK/STAT3 Signaling Pathway.
Zhang Q, Zhao C, Zhang L, Sun K, Yu L, Wang X, Ren L, Zhang N, Chen C, Liu J, Wang H, Tian H
Oxidative medicine and cellular longevity 2021;2021:9921839
Oxidative medicine and cellular longevity 2021;2021:9921839
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
Dou Q, Tong H, Yang Y, Zhang H, Gan H
BioMed research international 2021;2021:9884297
BioMed research international 2021;2021:9884297
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation.
Lou X, Mou Q, Zhao B, Huang J, Yao K, Luo Z, Ye M, Hu Y, Duan Q, Li X, Wen Z, Chen Z, Zhang H, Zhao Y
Oxidative medicine and cellular longevity 2021;2021:9397960
Oxidative medicine and cellular longevity 2021;2021:9397960
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Hypoxia-Induced Autophagy Enhances Cisplatin Resistance in Human Bladder Cancer Cells by Targeting Hypoxia-Inducible Factor-1α.
Mao X, Nanzhang, Xiao J, Wu H, Ding K
Journal of immunology research 2021;2021:8887437
Journal of immunology research 2021;2021:8887437
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
Zhao W, Wu Y, Ye F, Huang S, Chen H, Zhou R, Jiang W
BioMed research international 2021;2021:8870674
BioMed research international 2021;2021:8870674
Sodium Houttuyfonate Ameliorates β-amyloid(1-42)-Induced Memory Impairment and Neuroinflammation through Inhibiting the NLRP3/GSDMD Pathway in Alzheimer's Disease.
Zhao Y, Tian Y, Feng T
Mediators of inflammation 2021;2021:8817698
Mediators of inflammation 2021;2021:8817698
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Zhang Y, Chen G, Zhuang X, Guo M
Oxidative medicine and cellular longevity 2021;2021:8807676
Oxidative medicine and cellular longevity 2021;2021:8807676
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Zhang J, Cheng P, Dai W, Ji J, Wu L, Feng J, Wu J, Yu Q, Li J, Guo C
PPAR research 2021;2021:6658944
PPAR research 2021;2021:6658944
Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.
Cheng Z, Guo C
PPAR research 2021;2021:6632137
PPAR research 2021;2021:6632137
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
Guo J, Zhao D, Dong P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway.
Wang Y, Bai B, Hu Y, Wang H, Liu N, Li Y, Li P, Zhou G, Zhou Q
Stem cells international 2021;2021:5626487
Stem cells international 2021;2021:5626487
Programmed NP Cell Death Induced by Mitochondrial ROS in a One-Strike Loading Disc Degeneration Organ Culture Model.
Li BL, Liu X, Gao M, Zhang F, Chen X, He Z, Wang J, Tian W, Chen D, Zhou Z, Liu S
Oxidative medicine and cellular longevity 2021;2021:5608133
Oxidative medicine and cellular longevity 2021;2021:5608133
Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling.
Qu L, Lin P, Lin M, Ye S, Papa Akuetteh PD, Youyou Zhu
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5540139
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5540139
TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.
Zhang Z, Chang M, Song X, Wang K, Sun W, Ma H, Yan X, Sun Y, Song X, Xie L
Journal of oncology 2021;2021:5538911
Journal of oncology 2021;2021:5538911
Mechanism by Which Tong Xie Yao Fang Heals the Intestinal Mucosa of Rats with Ulcerative Colitis through the Hippo Pathway.
You W, Xu Z, Di A, Liu P, Pang C, Wang J, Li X, Wang Y, Yu B, Liu X, Zhao G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5533914
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5533914
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Yang K, Wu K, Feng J, Yutian L, Zhu X, Xu D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
He J, Liu J, Huang Y, Tang X, Xiao H, Liu Z, Jiang Z, Zeng L, Hu Z, Lu M
Oxidative medicine and cellular longevity 2021;2021:4805040
Oxidative medicine and cellular longevity 2021;2021:4805040
Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways.
Che X, Zhan J, Zhao F, Zhong Z, Chen M, Han R, Wang Y
BioMed research international 2021;2021:4340950
BioMed research international 2021;2021:4340950
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
Pei Z, Wang X, Yang C, Dong M, Wang F
Oxidative medicine and cellular longevity 2021;2021:3899356
Oxidative medicine and cellular longevity 2021;2021:3899356
γ-Glutamylcysteine Alleviates Ischemic Stroke-Induced Neuronal Apoptosis by Inhibiting ROS-Mediated Endoplasmic Reticulum Stress.
Li HQ, Xia SN, Xu SY, Liu PY, Gu Y, Bao XY, Xu Y, Cao X
Oxidative medicine and cellular longevity 2021;2021:2961079
Oxidative medicine and cellular longevity 2021;2021:2961079
TSH Combined with TSHR Aggravates Diabetic Peripheral Neuropathy by Promoting Oxidative Stress and Apoptosis in Schwann Cells.
Fan J, Pan Q, Gao Q, Li W, Xiao F, Guo L
Oxidative medicine and cellular longevity 2021;2021:2482453
Oxidative medicine and cellular longevity 2021;2021:2482453
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Xin Y, Shang X, Sun X, Liu Y, Xu G, Xue G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress.
He M, Long P, Chen T, Li K, Wei D, Zhang Y, Wang W, Hu Y, Ding Y, Wen A
Oxidative medicine and cellular longevity 2021;2021:1641717
Oxidative medicine and cellular longevity 2021;2021:1641717
Resistance of bone marrow mesenchymal stem cells in a stressed environment - Comparison with osteocyte cells.
Shimasaki M, Ueda S, Ichiseki T, Hirata H, Kawahara N, Ueda Y
International journal of medical sciences 2021;18(6):1375-1381
International journal of medical sciences 2021;18(6):1375-1381
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
Qin T, Cui XY, Xiu H, Huang C, Sun ZN, Xu XM, Li LH, Yue L
International journal of medical sciences 2021;18(2):325-334
International journal of medical sciences 2021;18(2):325-334
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
Zhang H, Xia P, Liu J, Chen Z, Ma W, Yuan Y
International journal of biological sciences 2021;17(15):4442-4458
International journal of biological sciences 2021;17(15):4442-4458
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Wang CM, Li HF, Wang XK, Li WG, Su Q, Xiao X, Hao TF, Chen W, Zhang YW, Zhang HY, Wu W, Hu ZR, Zhao GY, Huo MY, He YL, Zhang CH
International journal of biological sciences 2021;17(11):2811-2825
International journal of biological sciences 2021;17(11):2811-2825
Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.
Zhou Y, Yang Q, Wang F, Zhou Z, Xu J, Cheng S, Cheng Y
International journal of nanomedicine 2021;16:1805-1817
International journal of nanomedicine 2021;16:1805-1817
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Xing Y, Zhang M, Wang MM, Feng YS, Dong F, Zhang F
Frontiers in cellular neuroscience 2021;15:633280
Frontiers in cellular neuroscience 2021;15:633280
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Shi Y, Chen X, Liu J, Fan X, Jin Y, Gu J, Liang J, Liang X, Wang C
Frontiers in neuroscience 2021;15:555543
Frontiers in neuroscience 2021;15:555543
Integrating Network Pharmacology and Experimental Verification to Explore the Mechanism of Effect of Zuojin Pills in Pancreatic Cancer Treatment.
Wang K, Miao X, Kong F, Huang S, Mo J, Jin C, Zheng Y
Drug design, development and therapy 2021;15:3749-3764
Drug design, development and therapy 2021;15:3749-3764
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Ma L, Wu F, Shao Q, Chen G, Xu L, Lu F
Drug design, development and therapy 2021;15:3207-3221
Drug design, development and therapy 2021;15:3207-3221
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Ding L, Ren C, Yang L, Wu Z, Li F, Jiang D, Zhu Y, Lu J
Drug design, development and therapy 2021;15:1797-1810
Drug design, development and therapy 2021;15:1797-1810
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Yang Y, Yi J, Pan M, Hu B, Duan H
Drug design, development and therapy 2021;15:1409-1422
Drug design, development and therapy 2021;15:1409-1422
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Wang H, Jiang Z, Pang Z, Qi G, Hua B, Yan Z, Yuan H
Journal of inflammation research 2021;14:745-760
Journal of inflammation research 2021;14:745-760
Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma.
Gu W, Chen P, Ren P, Wang Y, Li X, Gong M
OncoTargets and therapy 2021;14:2917-2927
OncoTargets and therapy 2021;14:2917-2927
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
Tu Z, Jiang X, Li Y, Yang S, Lin D, Shi Y, Mao C, Zhang X, Lin C
American journal of translational research 2021;13(3):1337-1351
American journal of translational research 2021;13(3):1337-1351
miR-21-5p inhibits inflammation injuries in LPS-treated H9c2 cells by regulating PDCD4.
Xue J, Liu J, Xu B, Yu J, Zhang A, Qin L, Liu C, Yang Y
American journal of translational research 2021;13(10):11450-11460
American journal of translational research 2021;13(10):11450-11460
LncRNA TMPO-AS1 serves as a sponge for miR-4731-5p modulating breast cancer progression through FOXM1.
Wang Y, Ma J, Li R, Gao X, Wang H, Jiang G
American journal of translational research 2021;13(10):11094-11106
American journal of translational research 2021;13(10):11094-11106
Role of Cytokines Released During Pyroptosis in Non-Small Cell Lung Cancer.
Huang Y, Zhang G, Zhu Q, Wu X, Wu L
Cancer management and research 2021;13:7399-7409
Cancer management and research 2021;13:7399-7409
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
Dang Y, Zhou Y, Ou X, Wang Q, Wei D, Xie F
Cancer management and research 2021;13:7277-7288
Cancer management and research 2021;13:7277-7288
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
Liu C, Han X, Li B, Huang S, Zhou Z, Wang Z, Wang W
Cancer management and research 2021;13:6879-6889
Cancer management and research 2021;13:6879-6889
SAA1 knockdown promotes the apoptosis of glioblastoma cells via downregulation of AKT signaling.
Zhang H, Xu Y, Deng G, Yuan F, Tan Y, Gao L, Sun Q, Qi Y, Yang K, Geng R, Jiang H, Liu B, Chen Q
Journal of Cancer 2021;12(9):2756-2767
Journal of Cancer 2021;12(9):2756-2767
PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway.
Xu X, Xuan X, Zhang J, Xu H, Yang X, Zhang L, Zhao Y, Xu H, Li D
Journal of Cancer 2021;12(16):4945-4957
Journal of Cancer 2021;12(16):4945-4957
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Xin J, Cheng W, Yu Y, Chen J, Zhang X, Shao S
Frontiers in pharmacology 2021;12:806829
Frontiers in pharmacology 2021;12:806829
Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Fan S, Wang C, Huang K, Liang M
Frontiers in physiology 2021;12:790345
Frontiers in physiology 2021;12:790345
Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology.
Yi N, Mi Y, Xu X, Li N, Zeng F, Yan K, Tan K, Kuang G, Lu M
Frontiers in pharmacology 2021;12:788392
Frontiers in pharmacology 2021;12:788392
Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells.
Li G, Zhong Y, Wang W, Jia X, Zhu H, Jiang W, Song Y, Xu W, Wu S
Frontiers in pharmacology 2021;12:770667
Frontiers in pharmacology 2021;12:770667
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Yin Z, Geng X, Zhang Z, Wang Y, Gao X
Frontiers in pharmacology 2021;12:746711
Frontiers in pharmacology 2021;12:746711
Naringin Exerts Therapeutic Effects on Mice Colitis: A Study Based on Transcriptomics Combined With Functional Experiments.
Dong J, Chen Y, Yang F, Zhang W, Wei K, Xiong Y, Wang L, Zhou Z, Li C, Wang J, Chen D
Frontiers in pharmacology 2021;12:729414
Frontiers in pharmacology 2021;12:729414
Mechanisms Underlying the Effects of Lianhua Qingwen on Sepsis-Induced Acute Lung Injury: A Network Pharmacology Approach.
Yang R, Yang H, Wei J, Li W, Yue F, Song Y, He X, Hu K
Frontiers in pharmacology 2021;12:717652
Frontiers in pharmacology 2021;12:717652
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Han Y, Jiang M, He R, Lv X, Liao X, He Y, Zhang F, Long L, Jiang G, Peng Z, Tao L, Hu G, Meng J
Frontiers in pharmacology 2021;12:713572
Frontiers in pharmacology 2021;12:713572
Enterovirus 71 Induces INF2 Cleavage via Activated Caspase-2 in Infected RD Cells.
Wang B, Zhang C, Yu C, Zhu Y, Tang Q, Huang H, Zhao Z
Frontiers in microbiology 2021;12:684953
Frontiers in microbiology 2021;12:684953
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Wang T, Dong J, Yuan X, Wen H, Wu L, Liu J, Sui H, Deng W
Frontiers in pharmacology 2021;12:653306
Frontiers in pharmacology 2021;12:653306
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ji W, Wan T, Zhang F, Zhu X, Guo S, Mei X
Frontiers in pharmacology 2021;12:641058
Frontiers in pharmacology 2021;12:641058
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256
Frontiers in pharmacology 2021;12:639256
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Hu W, Wang R, Sun B
Frontiers in pharmacology 2021;12:627147
Frontiers in pharmacology 2021;12:627147
Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures.
Li C, Sui C, Wang W, Yan J, Deng N, Du X, Cheng F, Ma X, Wang X, Wang Q
Frontiers in pharmacology 2021;12:599543
Frontiers in pharmacology 2021;12:599543
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Lu J, Liu SY, Zhang J, Yang GM, Gao GB, Yu NN, Li YP, Li YX, Ma ZQ, Wang Y, Lu CH
American journal of cancer research 2021;11(7):3575-3593
American journal of cancer research 2021;11(7):3575-3593
Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.
Cheng Y, Wang G, Zhao L, Dai S, Han J, Hu X, Zhou C, Wang F, Ma H, Li B, Meng Z
Frontiers in oncology 2021;11:753598
Frontiers in oncology 2021;11:753598
The lncRNA CASC2 Modulates Hepatocellular Carcinoma Cell Sensitivity and Resistance to TRAIL Through Apoptotic and Non-Apoptotic Signaling.
Sun J, Xu H, Lei Z, Li Z, Zhu H, Deng Z, Yu X, Jin X, Yang Z
Frontiers in oncology 2021;11:726622
Frontiers in oncology 2021;11:726622
Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway.
Sun Y, Liu W, Zhao Q, Zhang R, Wang J, Pan P, Shang H, Liu C, Wang C
Frontiers in oncology 2021;11:653596
Frontiers in oncology 2021;11:653596
An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis.
Jin H, Zheng W, Hou J, Peng H, Zhuo H
Frontiers in oncology 2021;11:653246
Frontiers in oncology 2021;11:653246
A Novel Mechanism of the c-Myc/NEAT1 Axis Mediating Colorectal Cancer Cell Response to Photodynamic Therapy Treatment.
Liu K, Lei S, Kuang Y, Jin Q, Long D, Liu C, Jiang Y, Zhao H, Yao H
Frontiers in oncology 2021;11:652831
Frontiers in oncology 2021;11:652831
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Wen D, Liu WL, Lu ZW, Cao YM, Ji QH, Wei WJ
Frontiers in oncology 2021;11:647034
Frontiers in oncology 2021;11:647034
The Long Non-coding RNA TMPO-AS1 Promotes Bladder Cancer Growth and Progression via OTUB1-Induced E2F1 Deubiquitination.
Zhang Y, Zhu Y, Xiao M, Cheng Y, He D, Liu J, Xiang L, Gong L, Wang Z, Deng L, Cao K
Frontiers in oncology 2021;11:643163
Frontiers in oncology 2021;11:643163
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Guo W, Ma X, Fu Y, Liu C, Liu Q, Hu F, Miao H, Zhang T, Liu Y, Han MH, You F, Yang Y, Zheng W
Frontiers in oncology 2021;11:635233
Frontiers in oncology 2021;11:635233
Downregulating Long Non-coding RNAs CTBP1-AS2 Inhibits Colorectal Cancer Development by Modulating the miR-93-5p/TGF-β/SMAD2/3 Pathway.
Li Q, Yue W, Li M, Jiang Z, Hou Z, Liu W, Ma N, Gan W, Li Y, Zhou T, Yue W, Chen S
Frontiers in oncology 2021;11:626620
Frontiers in oncology 2021;11:626620
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
Liu J, He J, Huang Y, Ge L, Xiao H, Zeng L, Jiang Z, Lu M, Hu Z
Annals of translational medicine 2021 Sep;9(17):1362
Annals of translational medicine 2021 Sep;9(17):1362
SPAG6-silencing enhances decitabine-induced apoptosis and demethylation of PTEN in SKM-1 cells and in a xenograft mouse model.
Luo J, Mu J, Zhang M, Zhao B, Liu L
Leukemia & lymphoma 2021 Sep;62(9):2242-2252
Leukemia & lymphoma 2021 Sep;62(9):2242-2252
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Lin F, Zhen F, Yan X, Shaojun Y, Guizhu P, Yanfeng W, Qifa Y
Artificial organs 2021 Sep;45(9):E304-E316
Artificial organs 2021 Sep;45(9):E304-E316
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Dong JY, Xia KJ, Liang W, Liu LL, Yang F, Fang XS, Xiong YJ, Wang L, Zhou ZJ, Li CY, Zhang WD, Wang JY, Chen DP
Acta pharmacologica Sinica 2021 Sep;42(9):1461-1471
Acta pharmacologica Sinica 2021 Sep;42(9):1461-1471
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Yang LY, Cheng ZJ, Liu Z, Wang D, Zhang N, Fan ZL, Cai HQ, Zhang Y, Cai Y, Xu X, Wang JH, Du GH, Hao JJ, Wang MR
Journal of gastroenterology and hepatology 2021 Sep;36(9):2513-2522
Journal of gastroenterology and hepatology 2021 Sep;36(9):2513-2522
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
Wang D, Liu J, Jiang H
Environmental toxicology 2021 Sep;36(9):1953-1964
Environmental toxicology 2021 Sep;36(9):1953-1964
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Wu J, Wu T, Zheng S, Huang Y, Wang L
Experimental eye research 2021 Sep;210:108696
Experimental eye research 2021 Sep;210:108696
Knockdown of PYCR1 suppressed the malignant phenotype of human hepatocellular carcinoma cells via inhibiting the AKT pathway activation.
Guo J, Cheng X, Tian Y, Li B, Zhang X, Gao X, An Y
Reproductive biology 2021 Sep;21(3):100534
Reproductive biology 2021 Sep;21(3):100534
Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease.
Cheng B, Liang C, Yang X, Li P, Liu L, Cheng S, Jia Y, Zhang L, Ma M, Qi X, Yao Y, Chu X, Ye J, Lu C, Guo X, Wen Y, Zhang F
Bone 2021 Sep;150:115997
Bone 2021 Sep;150:115997
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Li H, Yang W, Zhang M, He T, Zhou F, G Herman J, Hu L, Guo M
Epigenomics 2021 Sep;13(17):1403-1419
Epigenomics 2021 Sep;13(17):1403-1419
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma.
Xia T, Tian H, Zhang K, Zhang S, Chen W, Shi S, You Y
BMC cancer 2021 Sep 8;21(1):1003
BMC cancer 2021 Sep 8;21(1):1003
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Xu HZ, Li TF, Wang C, Ma Y, Liu Y, Zheng MY, Liu ZJ, Chen JB, Li K, Sun SK, Komatsu N, Xu YH, Zhao L, Chen X
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Li TF, Xu HZ, Xu YH, Yu TT, Tang JM, Li K, Wang C, Peng XC, Li QR, Sang XY, Zheng MY, Liu Y, Zhao L, Chen X
Molecular pharmaceutics 2021 Sep 6;18(9):3601-3615
Molecular pharmaceutics 2021 Sep 6;18(9):3601-3615
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
Yuan SJ, Wang C, Xu HZ, Liu Y, Zheng MY, Li K, Sun SK, Komatsu N, Zhao L, Chen X
International journal of pharmaceutics 2021 Sep 5;606:120872
International journal of pharmaceutics 2021 Sep 5;606:120872
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
Zhang Z, Ye C, Liu J, Xu W, Wu C, Yu Q, Xu X, Zeng X, Jin H, Wu Y, Yan H
Cancer biology & medicine 2021 Sep 28;19(5):651-68
Cancer biology & medicine 2021 Sep 28;19(5):651-68
Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer.
Sun Y, Ren D, Zhou Y, Shen J, Wu H, Jin X
Cell death & disease 2021 Sep 25;12(10):878
Cell death & disease 2021 Sep 25;12(10):878
Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation.
Liu KL, Li XY, Wang DP, Xue WH, Qian XH, Li YH, Lin QQ, Li S, Meng FH
Journal of medicinal chemistry 2021 Sep 23;64(18):13356-13372
Journal of medicinal chemistry 2021 Sep 23;64(18):13356-13372
TRAIL produced by SAM-1-activated CD4(+) and CD8(+) subgroup T cells induces apoptosis in human tumor cells through upregulation of death receptors.
Zhang G, Xu M, Zhang X, Ma L, Zhang H
Toxicology and applied pharmacology 2021 Sep 15;427:115656
Toxicology and applied pharmacology 2021 Sep 15;427:115656
Hydroxychloroquine alleviates the neurotoxicity induced by anti-ribosomal P antibodies.
Zhao X, Yang P
Journal of neuroimmunology 2021 Sep 15;358:577648
Journal of neuroimmunology 2021 Sep 15;358:577648
Rubioncolin C, a natural naphthohydroquinone dimer isolated from Rubia yunnanensis, inhibits the proliferation and metastasis by inducing ROS-mediated apoptotic and autophagic cell death in triple-negative breast cancer cells.
Li L, Wang J, Feng L, Fan J, Wang J, Tan N, Wang Z
Journal of ethnopharmacology 2021 Sep 15;277:114184
Journal of ethnopharmacology 2021 Sep 15;277:114184
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Zhu X, Yu Z, Feng L, Deng L, Fang Z, Liu Z, Li Y, Wu X, Qin L, Guo R, Zheng Y
Carbohydrate polymers 2021 Sep 15;268:118237
Carbohydrate polymers 2021 Sep 15;268:118237
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Lan J, Hu Y, Wang X, Zheng W, Liao A, Wang S, Li Y, Wang Y, Yang F, Chen D
Neuropharmacology 2021 Sep 15;196:108689
Neuropharmacology 2021 Sep 15;196:108689
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Esculetin inhibits endometrial cancer proliferation and promotes apoptosis via hnRNPA1 to downregulate BCLXL and XIAP.
Jiang R, Su G, Chen X, Chen S, Li Q, Xie B, Zhao Y
Cancer letters 2021 Sep 1;521:308-321
Cancer letters 2021 Sep 1;521:308-321
Prolonged exposure to the herbicide atrazine suppresses immune cell functions by inducing spleen cell apoptosis in rats.
Ge J, Liu J, Wang T, Huang D, Li J, Zhang S, Wang M, Liu W, Zhao L
Ecotoxicology and environmental safety 2021 Sep 1;220:112386
Ecotoxicology and environmental safety 2021 Sep 1;220:112386
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Cell biology and toxicology 2021 Oct;37(5):795-809
Cell biology and toxicology 2021 Oct;37(5):795-809
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
Li M, Chen X, Wang X, Wei X, Wang D, Liu X, Xu L, Batu W, Li Y, Guo B, Zhang L
Biochemical pharmacology 2021 Oct;192:114741
Biochemical pharmacology 2021 Oct;192:114741
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Zhao Y, Yang X, Li S, Zhang B, Li S, Wang X, Wang Y, Jia C, Chang Y, Wei W
Stem cell research & therapy 2021 Oct 9;12(1):535
Stem cell research & therapy 2021 Oct 9;12(1):535
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
Yao W, Pan Z, Du X, Zhang J, Liu H, Li Q
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034
Cell death & disease 2021 Oct 30;12(11):1034
Curcuma oil ameliorates benign prostatic hyperplasia through suppression of the nuclear factor-kappa B signaling pathway in rats.
Wang S, Li Y, Li W, Zhang K, Yuan Z, Cai Y, Xu K, Zhou J, Du Z
Journal of ethnopharmacology 2021 Oct 28;279:113703
Journal of ethnopharmacology 2021 Oct 28;279:113703
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
Zheng Y, Niu B, Zhang W, Ru X, Gao Y, Li C, Wu X
Aging 2021 Oct 25;13(20):23757-23768
Aging 2021 Oct 25;13(20):23757-23768
Sequential drug delivery by injectable macroporous hydrogels for combined photodynamic-chemotherapy.
Zhong Y, Zhang L, Sun S, Zhou Z, Ma Y, Hong H, Yang D
Journal of nanobiotechnology 2021 Oct 23;19(1):333
Journal of nanobiotechnology 2021 Oct 23;19(1):333
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway.
Ma Y, Li S, Ye S, Tang S, Hu D, Wei L, Xiao F
Ecotoxicology and environmental safety 2021 Oct 15;223:112614
Ecotoxicology and environmental safety 2021 Oct 15;223:112614
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
Wang D, Wei X, Chen X, Wang Q, Zhang J, Kalvakolanu DV, Guo B, Zhang L
Experimental cell research 2021 Oct 1;407(1):112799
Experimental cell research 2021 Oct 1;407(1):112799
Imidacloprid increases intestinal permeability by disrupting tight junctions.
Zhao GP, Wang XY, Li JW, Wang R, Ren FZ, Pang GF, Li YX
Ecotoxicology and environmental safety 2021 Oct 1;222:112476
Ecotoxicology and environmental safety 2021 Oct 1;222:112476
Comparison of biological and transcriptomic effects of conventional cigarette and electronic cigarette smoke exposure at toxicological dose in BEAS-2B cells.
Wang L, Wang Y, Chen J, Yang XM, Jiang XT, Liu P, Li M
Ecotoxicology and environmental safety 2021 Oct 1;222:112472
Ecotoxicology and environmental safety 2021 Oct 1;222:112472
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
Zhou M, Chen X, Bai H, Sun Y, Zhang Z, Li S, Wang X, Zeng M
DNA and cell biology 2021 Nov;40(11):1418-1427
DNA and cell biology 2021 Nov;40(11):1418-1427
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
Wang N, Zhu P, Huang R, Sun L, Dong D, Gao Y
Experimental and therapeutic medicine 2021 Nov;22(5):1246
Experimental and therapeutic medicine 2021 Nov;22(5):1246
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Chen Q, Li Z, Xu Z, Chen C, Wang J, Zhu J, Dong Z
Biological trace element research 2021 Nov;199(11):4119-4128
Biological trace element research 2021 Nov;199(11):4119-4128
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
He R, Wang Z, Cui M, Liu S, Wu W, Chen M, Wu Y, Qu Y, Lin H, Chen S, Wang B, Shao Z
Autophagy 2021 Nov;17(11):3338-3360
Autophagy 2021 Nov;17(11):3338-3360
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Wang L, Wang X, Kong L, Wang S, Huang K, Wu J, Wang C, Sun H, Liu K, Meng Q
International immunopharmacology 2021 Nov;100:108159
International immunopharmacology 2021 Nov;100:108159
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
Ji J, Wang Z, Sun W, Li Z, Cai H, Zhao E, Cui H
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC
Food & function 2021 Nov 29;12(23):12142-12158
Food & function 2021 Nov 29;12(23):12142-12158
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling.
Xiao Y, Liu Y, Gao Z, Li X, Weng M, Shi C, Wang C, Sun L
Aging 2021 Nov 25;13(22):24753-24767
Aging 2021 Nov 25;13(22):24753-24767
WNK3 Promotes Neuronal Survival after Traumatic Brain Injury in Rats.
Zhu J, Lin X, Chen C, Tan H, Gao Y, Li D, Chen G
Neuroscience 2021 Nov 21;477:76-88
Neuroscience 2021 Nov 21;477:76-88
Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer.
Zheng S, Wang J, Ding N, Chen W, Chen H, Xue M, Chen F, Ni J, Wang Z, Lin Z, Jiang H, Liu X, Wang L
Journal of nanobiotechnology 2021 Nov 21;19(1):381
Journal of nanobiotechnology 2021 Nov 21;19(1):381
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Xi H, Ren F, Li Y, Du Y, Wang L, Hu J
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Biology of reproduction 2021 Nov 15;105(5):1344-1354
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.
Liu S, Zhang Y, Cui S, Song D, Li B, Chen Q, Yao G, Gong B
Cancer cell international 2021 Nov 13;21(1):605
Cancer cell international 2021 Nov 13;21(1):605
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
Zheng L, Ren R, Sun X, Zou Y, Shi Y, Di B, Niu MM
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
Anti-glioblastoma effects of nanomicelle-curcumin plus erlotinib.
Bagherian A, Roudi B, Masoudian N, Mirzaei H
Food & function 2021 Nov 1;12(21):10926-10937
Food & function 2021 Nov 1;12(21):10926-10937
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Lu YZ, Zhang CQ, Yu BX, Zhang EH, Quan H, Yin X, Cai H, Yuan F, Li LQ, Xu YJ, Su YJ, Xing YJ, Liao ZH, Lan XZ
Food science & nutrition 2021 May;9(5):2402-2413
Food science & nutrition 2021 May;9(5):2402-2413
Activation of HSP70 impedes tert-butyl hydroperoxide (t-BHP)-induced apoptosis and senescence of human nucleus pulposus stem cells via inhibiting the JNK/c-Jun pathway.
Zhang S, Liu W, Wang P, Hu B, Lv X, Chen S, Wang B, Shao Z
Molecular and cellular biochemistry 2021 May;476(5):1979-1994
Molecular and cellular biochemistry 2021 May;476(5):1979-1994
Near-infrared emission Cu, N-doped carbon dots for human umbilical vein endothelial cell labeling and their biocompatibility in vitro.
Zhu P, Zhang T, Li J, Ma J, Ouyang X, Zhao X, Xu M, Wang D, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):789-798
Journal of applied toxicology : JAT 2021 May;41(5):789-798
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
Hu J, Huo S, Dou S, Jiang W, Li Y
General physiology and biophysics 2021 May;40(3):161-171
General physiology and biophysics 2021 May;40(3):161-171
Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy.
Liu X, Zheng Q, Yu Q, Hu Y, Cheng Y, Shao Z, Chen L, Ding W, Gao D
Naunyn-Schmiedeberg's archives of pharmacology 2021 May;394(5):1009-1018
Naunyn-Schmiedeberg's archives of pharmacology 2021 May;394(5):1009-1018
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Zhong BR, Zhou GF, Song L, Wen QX, Deng XJ, Ma YL, Hu LT, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway.
Huang N, Cui X, Li W, Zhang C, Liu L, Li J
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
Xu S, Jiang N, Nawaz W, Liu B, Zhang F, Liu Y, Wu X, Wu Z
PLoS pathogens 2021 May;17(5):e1009587
PLoS pathogens 2021 May;17(5):e1009587
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY, Xiang XJ, Song L, Chen J, Luo B, Wen QX, Zhong BR, Zhou GF, Deng XJ, Ma YL, Hu LT, Chen GJ
Journal of neurochemistry 2021 May;157(4):1351-1365
Journal of neurochemistry 2021 May;157(4):1351-1365
Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis.
Jiang S, Wang X, He Y, Huang H, Cao B, Zhang Z, Liu J, Wang Q, Huang Z, Mao X
Cell death & disease 2021 May 7;12(5):456
Cell death & disease 2021 May 7;12(5):456
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
Jiang Y, Liu H, Yu H, Zhou Y, Zhang J, Xin W, Li Y, He S, Ma C, Zheng X, Zhang L, Zhao X, Wu B, Jiang C, Zhu D
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693
[Heat stress induces neuronal apoptosis by up-regulating endoplasmic reticulum stress pathway].
Gao J, Liu Y, Ji J, Liu Z
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):702-709
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):702-709
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Cao Y, Tang S, Nie X, Zhou Z, Ruan G, Han W, Zhu Z, Ding C
EBioMedicine 2021 Mar;65:103283
EBioMedicine 2021 Mar;65:103283
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Li X, Zhou W, Li Z, Guan F
Autoimmunity 2021 Mar;54(2):114-128
Autoimmunity 2021 Mar;54(2):114-128
Chlorogenic acid inhibits proliferation in human hepatoma cells by suppressing noncanonical NF-κB signaling pathway and triggering mitochondrial apoptosis.
Jiang Y, Nan H, Shi N, Hao W, Dong J, Chen H
Molecular biology reports 2021 Mar;48(3):2351-2364
Molecular biology reports 2021 Mar;48(3):2351-2364
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Zhu S, Liu X, Xue M, Li Y, Cai D, Wang S, Zhang L
Journal of ginseng research 2021 Mar;45(2):295-304
Journal of ginseng research 2021 Mar;45(2):295-304
KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer.
Xiong Y, Ju L, Yuan L, Chen L, Wang G, Xu H, Peng T, Luo Y, Xiao Y, Wang X
Oncogene 2021 Mar;40(9):1595-1608
Oncogene 2021 Mar;40(9):1595-1608
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Zhou X, Zhang X, Wu Z, Xu X, Guo M, Zhai X, Zuo D, Wu Y
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22666
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22666
Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia-reperfusion injury.
Lu S, Tian Y, Luo Y, Xu X, Ge W, Sun G, Sun X
Journal of advanced research 2021 Mar;29:83-94
Journal of advanced research 2021 Mar;29:83-94
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Sperm Parameters, ASAs and Apoptosis After Processing by the Double Tube and Swim up Methods.
Shi ZD, Zhang YP, Zhai LP, Zhang MH, Dong YL, Yang HJ, Qiu Y
American journal of men's health 2021 Mar-Apr;15(2):15579883211001202
American journal of men's health 2021 Mar-Apr;15(2):15579883211001202
circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression.
Chen Z, Xu W, Zhang D, Chu J, Shen S, Ma Y, Wang Q, Liu G, Yao T, Huang Y, Ye H, Wang J, Ma J, Fan S
Molecular therapy. Nucleic acids 2021 Mar 5;23:1120-1135
Molecular therapy. Nucleic acids 2021 Mar 5;23:1120-1135
PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer.
Jiang TY, Feng XF, Fang Z, Cui XW, Lin YK, Pan YF, Yang C, Ding ZW, Zhang YJ, Tan YX, Wang HY, Dong LW
Cancer letters 2021 Mar 31;501:187-199
Cancer letters 2021 Mar 31;501:187-199
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
Gao J, Feng W, Lv W, Liu W, Fu C
International heart journal 2021 Mar 30;62(2):350-358
International heart journal 2021 Mar 30;62(2):350-358
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.
Yang MH, Chen YA, Tu SC, Chi PL, Chuang KP, Chang CC, Lee CH, Chen YL, Lee CH, Yuan CH, Tyan YC
International journal of molecular sciences 2021 Mar 23;22(6)
International journal of molecular sciences 2021 Mar 23;22(6)
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Tai H, Jiang XL, Lan ZM, Li Y, Kong L, Yao SC, Song N, Lv MJ, Wu J, Yang P, Xiao XS, Yang GL, Kuang JS, Jia LQ
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Zhang S, Shao Z, Liu X, Hou M, Cheng F, Lei D, Yuan H
Cell death discovery 2021 Mar 15;7(1):49
Cell death discovery 2021 Mar 15;7(1):49
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
Wang ZG, Zhu ZQ, He ZY, Cheng P, Liang S, Chen AM, Yang Q
Aging 2021 Mar 10;13(6):8454-8466
Aging 2021 Mar 10;13(6):8454-8466
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1α pathway.
Wang H, Dou S, Zhu J, Shao Z, Wang C, Xu X, Cheng B
Neuropeptides 2021 Jun;87:102134
Neuropeptides 2021 Jun;87:102134
Adenine nucleotide translocase 2, a putative target protein for 2-carba cyclic phosphatidic acid in microglial cells.
Tsukahara T, Sahara Y, Ribeiro N, Tsukahara R, Gotoh M, Sakamoto S, Handa H, Murakami-Murofushi K
Cellular signalling 2021 Jun;82:109951
Cellular signalling 2021 Jun;82:109951
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of Alzheimer's disease.
Övey İS, Nazıroğlu M
Journal of receptor and signal transduction research 2021 Jun;41(3):273-283
Journal of receptor and signal transduction research 2021 Jun;41(3):273-283
Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy.
Shao Z, Dou S, Zhu J, Wang H, Xu D, Wang C, Cheng B, Bai B
Neurotoxicity research 2021 Jun;39(3):740-753
Neurotoxicity research 2021 Jun;39(3):740-753
Role of the BDNF/TrkB/CREB signaling pathway in the cytotoxicity of bisphenol S in SK-N-SH cells.
He QZ, Zhu BQ, Xu XN, Zeng HC
Journal of biochemical and molecular toxicology 2021 Jun;35(6):1-11
Journal of biochemical and molecular toxicology 2021 Jun;35(6):1-11
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Xu M, Lin B, Zheng D, Wen J, Hu W, Li C, Zhang X, Zhang X, Qu J
Oncology letters 2021 Jun;21(6):442
Oncology letters 2021 Jun;21(6):442
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
Han S, Wang Z, Liu J, Wang HD, Yuan Q
Biochemical pharmacology 2021 Jun;188:114539
Biochemical pharmacology 2021 Jun;188:114539
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1.
Duan Y, Jia Y, Wang J, Liu T, Cheng Z, Sang M, Lv W, Qin J, Liu L
Cell death & disease 2021 Jun 7;12(6):587
Cell death & disease 2021 Jun 7;12(6):587
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Pan H, Xu Y, Cai Q, Wu M, Ding M
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 4;27:e931884
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 4;27:e931884
Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells†.
Yang M, Guan S, Tao J, Zhu K, Lv D, Wang J, Li G, Gao Y, Wu H, Liu J, Cao L, Fu Y, Ji P, Lian Z, Zhang L, Liu G
Biology of reproduction 2021 Jun 4;104(6):1322-1336
Biology of reproduction 2021 Jun 4;104(6):1322-1336
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
Kuang W, Jiang W, Chen Y, Tian Y, Liu Z
Cancer biology & therapy 2021 Jun 3;22(5-6):392-403
Cancer biology & therapy 2021 Jun 3;22(5-6):392-403
Hypoxia induces chemoresistance of esophageal cancer cells to cisplatin through regulating the lncRNA-EMS/miR-758-3p/WTAP axis.
Zhu ZJ, Pang Y, Jin G, Zhang HY, Wang WH, Liu JW, Tuo GX, Wu P, Yang Y, Wang ZQ, Wang K
Aging 2021 Jun 3;13(13):17155-17176
Aging 2021 Jun 3;13(13):17155-17176
Pre-emptive pharmacological inhibition of fatty acid-binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism.
Chen Y, Dai Y, Song K, Huang Y, Zhang L, Zhang C, Yan Q, Gao H
Cell death & disease 2021 Jun 3;12(6):572
Cell death & disease 2021 Jun 3;12(6):572
Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.
Wang L, Zhang Y, Chen L, Wang J, Jia F, Li F, Froehlich TE, Hou Y, Hao Y, Shi Y, Deng H, Zhang J, Huang L, Xie X, Fang S, Xu L, Xu Q, Guan H, Wang W, Shen J, Qian Y, Wang X, Shan L, Tan C, Yu Y, Wang X, Chen F, Zhang L, Li X, Shi X, Ke X, Li T
Translational psychiatry 2021 Jun 3;11(1):342
Translational psychiatry 2021 Jun 3;11(1):342
Transforming Growth Factor Beta 1 and p44/42 Expression in Cardinal Ligament Tissues of Patients with Pelvic Organ Prolapse.
Zhao Y, Xia Z, Lin T, Qin M
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 28;27:e930433
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 28;27:e930433
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Zhou X, He Y, Li N, Bai G, Pan X, Zhang Z, Zhang H, Li J, Yuan X
Cell death & disease 2021 Jun 26;12(7):653
Cell death & disease 2021 Jun 26;12(7):653
TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression.
Zhang X, Zhao S, Yuan Q, Zhu L, Li F, Wang H, Kong D, Hao J
Cell death & disease 2021 Jun 23;12(7):642
Cell death & disease 2021 Jun 23;12(7):642
Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity.
Jin L, Gao F, Jiang T, Liu B, Li C, Qin X, Zheng Q
Biochemical and biophysical research communications 2021 Jun 18;558:126-133
Biochemical and biophysical research communications 2021 Jun 18;558:126-133
Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance.
Huang H, Zhang S, Li Y, Liu Z, Mi L, Cai Y, Wang X, Chen L, Ran H, Xiao D, Li F, Wu J, Li T, Han Q, Chen L, Pan X, Li H, Li T, He K, Li A, Zhang X, Zhou T, Xia Q, Man J
Nature communications 2021 Jun 17;12(1):3720
Nature communications 2021 Jun 17;12(1):3720
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.
Zhao X, Jiang L, Hu D, Tang Y, Zhao G, Du X, Luo S, Tang W
Experimental cell research 2021 Jun 15;403(2):112614
Experimental cell research 2021 Jun 15;403(2):112614
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Xu R, Zhang K, Liang J, Gao F, Li J, Guan F
Carbohydrate polymers 2021 Jun 1;261:117846
Carbohydrate polymers 2021 Jun 1;261:117846
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Zhou S, Zhou Y, Yu J, Jiang L, Xiang Y, Wang J, Du Y, Cui X, Ge F
Food science & nutrition 2021 Jul;9(7):3602-3616
Food science & nutrition 2021 Jul;9(7):3602-3616
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.
Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S, Zong WX
EBioMedicine 2021 Jul;69:103456
EBioMedicine 2021 Jul;69:103456
CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K‑Akt‑mTOR pathway inhibition.
Liao YX, Lv JY, Zhou ZF, Xu TY, Yang D, Gao QM, Fan L, Li GD, Yu HY, Liu KY
International journal of oncology 2021 Jul;59(1)
International journal of oncology 2021 Jul;59(1)
Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis.
Guan R, Li Z, Dai X, Zou W, Yu X, Liu H, Chen Q, Teng W, Liu P, Liu X, Dong S
Molecular medicine reports 2021 Jul;24(1)
Molecular medicine reports 2021 Jul;24(1)
Dynamin 3 overexpression suppresses the proliferation, migration and invasion of cervical cancer cells.
Fa J
Oncology letters 2021 Jul;22(1):524
Oncology letters 2021 Jul;22(1):524
2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop.
Zheng S, Ni J, Li Y, Lu M, Yao Y, Guo H, Jiao M, Jin T, Zhang H, Yuan A, Wang Z, Yang Y, Chen Z, Wu H, Hu W
Pharmacological research 2021 Jul;169:105685
Pharmacological research 2021 Jul;169:105685
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
Luo P, He WX, Li C, Chang MJ
Neuroreport 2021 Jul 7;32(10):875-881
Neuroreport 2021 Jul 7;32(10):875-881
NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process.
Shi C, Weng M, Zhu H, Guo Y, Xu D, Jin H, Wei B, Cao Z
Aging 2021 Jul 29;13(14):18298-18309
Aging 2021 Jul 29;13(14):18298-18309
Prognostic SLC family genes promote cell proliferation, migration, and invasion in hepatocellular carcinoma.
Fang X, Liu Y, Xiao W, Zhao N, Zhu C, Yu D, Zhao Y
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1065-1075
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1065-1075
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
Guo Y, Xiao Y, Guo H, Zhu H, Chen D, Wang J, Deng J, Lan J, Liu X, Zhang Q, Bai Y
Aging 2021 Jul 28;13(14):18545-18563
Aging 2021 Jul 28;13(14):18545-18563
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985
Scientific reports 2021 Jul 22;11(1):14985
Pseudoginsengenin DQ exerts antitumour activity against hypopharyngeal cancer cells by targeting the HIF-1α-GLUT1 pathway.
Wang S, Cai Y, Feng Q, Gao J, Teng B
Cancer cell international 2021 Jul 19;21(1):382
Cancer cell international 2021 Jul 19;21(1):382
Timolol induces necroptosis, apoptosis and senescence concentration-dependently in rabbit Limbal stem cells in vitro.
Jiang GJ, Li BB, Fan TJ
Life sciences 2021 Jul 15;277:119453
Life sciences 2021 Jul 15;277:119453
Type 2 Alveolar Epithelial Cells Differentiated from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Mouse Pulmonary Fibrosis Through β-Catenin-Regulated Cell Apoptosis.
Liu J, Peng D, You J, Zhou O, Qiu H, Hao C, Chen H, Fu Z, Zou L
Stem cells and development 2021 Jul 1;30(13):660-670
Stem cells and development 2021 Jul 1;30(13):660-670
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
Zhou G, Qin M, Zhang X, Yang J, Yu H
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Li Q, Chu Z, Geng S
Cancer investigation 2021 Jan;39(1):84-97
Cancer investigation 2021 Jan;39(1):84-97
Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway.
Zhou L, Wang S, Cao L, Ren X, Li Y, Shao J, Xu L
International journal of environmental health research 2021 Jan;31(1):34-44
International journal of environmental health research 2021 Jan;31(1):34-44
Metabolomic analysis of spontaneous neutrophil apoptosis reveals the potential involvement of glutathione depletion.
Yuyun X, Fan Y, Weiping W, Qing Y, Bingwei S
Innate immunity 2021 Jan;27(1):31-40
Innate immunity 2021 Jan;27(1):31-40
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Yang LR, Li L, Meng MY, Wang WJ, Yang SL, Zhao YY, Wang RQ, Gao H, Tang WW, Yang Y, Yang LL, Liao LW, Hou ZL
Journal of cellular and molecular medicine 2021 Jan;25(2):686-700
Journal of cellular and molecular medicine 2021 Jan;25(2):686-700
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z
Free radical biology & medicine 2021 Jan;162:181-190
Free radical biology & medicine 2021 Jan;162:181-190
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Liu C, Yu M, Li Y, Wang H, Xu C, Zhang X, Li M, Guo H, Ma D, Guo X
Cancer medicine 2021 Jan;10(1):337-349
Cancer medicine 2021 Jan;10(1):337-349
Melatonin Alleviates Hypoxia-Induced Apoptosis of Granulosa Cells by Reducing ROS and Activating MTNR1B-PKA-Caspase8/9 Pathway.
Tao JL, Zhang X, Zhou JQ, Li CY, Yang MH, Liu ZJ, Zhang LL, Deng SL, Zhang L, Shen M, Liu GS, Liu HL
Antioxidants (Basel, Switzerland) 2021 Jan 28;10(2)
Antioxidants (Basel, Switzerland) 2021 Jan 28;10(2)
Cytoprotective Effects of Taurine on Heat-Induced Bovine Mammary Epithelial Cells In Vitro.
Bai H, Li T, Yu Y, Zhou N, Kou H, Guo Y, Yang L, Yan P
Cells 2021 Jan 28;10(2)
Cells 2021 Jan 28;10(2)
Ameliorative effect of recombinant human lactoferrin on the premature ovarian failure in rats after cyclophosphamide treatments.
Li S, Liu M, Ma H, Jin Q, Ma Y, Wang C, Ren J, Liu G, Dai Y
Journal of ovarian research 2021 Jan 21;14(1):17
Journal of ovarian research 2021 Jan 21;14(1):17
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Zhang X, Zhu M, Wang H, Song Z, Zhan D, Cao W, Han Y, Jia J
Gene 2021 Jan 15;766:145163
Gene 2021 Jan 15;766:145163
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
He J, Huang Y, Liu J, Ge L, Tang X, Lu M, Hu Z
Life sciences 2021 Jan 15;265:118861
Life sciences 2021 Jan 15;265:118861
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Yang W, Liu J, Hou L, Chen Q, Liu Y
Life sciences 2021 Jan 15;265:118796
Life sciences 2021 Jan 15;265:118796
Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration.
Guo Z, Qiu C, Mecca C, Zhang Y, Bian J, Wang Y, Wu X, Wang T, Su W, Li X, Zhang W, Chen B, Xiang H
BMC musculoskeletal disorders 2021 Jan 13;22(1):77
BMC musculoskeletal disorders 2021 Jan 13;22(1):77
LncRNA SNHG16 contributes to tumor progression via the miR-302b-3p/SLC2A4 axis in pancreatic adenocarcinoma.
Xu H, Miao X, Li X, Chen H, Zhang B, Zhou W
Cancer cell international 2021 Jan 12;21(1):51
Cancer cell international 2021 Jan 12;21(1):51
Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study.
Huang Y, Zhang J, Dong R, Ji X, Jiang Y, Cen J, Bai Z, Hong K, Li H, Chen J, Zhou J, Qian F, Wang F, Qu Y, Zhou Y
BMC complementary medicine and therapies 2021 Jan 11;21(1):26
BMC complementary medicine and therapies 2021 Jan 11;21(1):26
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Qiu Y, Ren K, Zhao W, Yu Q, Guo R, He J, Mei L, Liu Y, Tang J, Xu S, Li J, Wei J, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
ALKBH5-mediated m(6)A demethylation of FOXM1 mRNA promotes progression of uveal melanoma.
Hao L, Yin J, Yang H, Li C, Zhu L, Liu L, Zhong J
Aging 2021 Jan 10;13(3):4045-4062
Aging 2021 Jan 10;13(3):4045-4062
Deficiency of NEAT1 prevented MPP(+)-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
Zhou S, Zhang D, Guo J, Chen Z, Chen Y, Zhang J
Brain research 2021 Jan 1;1750:147156
Brain research 2021 Jan 1;1750:147156
Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters.
Ye N, Lv Z, Dai H, Huang Z, Shi F
Theriogenology 2021 Jan 1;159:20-27
Theriogenology 2021 Jan 1;159:20-27
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation.
Han Q, Zhang C, Zhang Y, Li Y, Wu L, Sun X
Pharmacology research & perspectives 2021 Feb;9(1):e00694
Pharmacology research & perspectives 2021 Feb;9(1):e00694
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Jiao Y, Zhao D, Gao F, Hu X, Hu X, Li M, Cui Y, Wei X, Xie C, Zhao Y, Gao Y
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Curcumin Ameliorates Copper-Induced Neurotoxicity Through Inhibiting Oxidative Stress and Mitochondrial Apoptosis in SH-SY5Y Cells.
Xiang B, Li D, Chen Y, Li M, Zhang Y, Sun T, Tang S
Neurochemical research 2021 Feb;46(2):367-378
Neurochemical research 2021 Feb;46(2):367-378
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Wo X, Yuan Y, Xu Y, Chen Y, Wang Y, Zhao S, Lin L, Zhong X, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2021 Feb;36(1):95-103
Virologica Sinica 2021 Feb;36(1):95-103
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Yu Y, Sun H, Zhu L, Ji L, Liu H
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
PRSS55 plays an important role in the structural differentiation and energy metabolism of sperm and is required for male fertility in mice.
Zhu F, Li W, Zhou X, Chen X, Zheng M, Cui Y, Liu X, Guo X, Zhu H
Journal of cellular and molecular medicine 2021 Feb;25(4):2040-2051
Journal of cellular and molecular medicine 2021 Feb;25(4):2040-2051
Increased expression of IFN-γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop.
Liu H, Wang W, Liu C
Experimental and therapeutic medicine 2021 Feb;21(2):112
Experimental and therapeutic medicine 2021 Feb;21(2):112
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
Yak milk-derived exosomal microRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment.
Gao HN, Ren FZ, Wen PC, Xie LX, Wang R, Yang ZN, Li YX
Journal of dairy science 2021 Feb;104(2):1291-1303
Journal of dairy science 2021 Feb;104(2):1291-1303
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Xiang T, Yuan C, Guo X, Wang H, Cai Q, Xiang Y, Luo W, Liu G
Cell death & disease 2021 Feb 4;12(2):150
Cell death & disease 2021 Feb 4;12(2):150
GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway.
Yu X, Jin J, Zheng Y, Zhu H, Xu H, Ma J, Lan Q, Zhuang Z, Chen CC, Li M
Cell death & disease 2021 Feb 19;12(2):203
Cell death & disease 2021 Feb 19;12(2):203
CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma.
Liu T, Han X, Zheng S, Liu Q, Tuerxun A, Zhang Q, Yang L, Lu X
Cancer cell international 2021 Feb 18;21(1):121
Cancer cell international 2021 Feb 18;21(1):121
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Feng Z, Wang C, Yue, Jin, Meng Q, Wu J, Sun H
Pharmaceutical biology 2021 Dec;59(1):1106-1116
Pharmaceutical biology 2021 Dec;59(1):1106-1116
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Lu C, Liu L, Chen S, Niu J, Li S, Xie W, Cheng X
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
Chen Y, Tian Y, Jin G, Cui Z, Guo W, Zhang X, Liu X
Human & experimental toxicology 2021 Dec;40(12):2074-2086
Human & experimental toxicology 2021 Dec;40(12):2074-2086
AK003290 Protects Myocardial Cells Against Apoptosis and Promotes Cardiac Function Recovery Via miR-539-3p/ErbB4 Axis in Ischemic-Reperfusion Injury.
Tang Y, Tang Y, Xiang Y, Yan J, Guo K
DNA and cell biology 2021 Dec;40(12):1528-1538
DNA and cell biology 2021 Dec;40(12):1528-1538
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Liu Y, Liu Y, Zhang HL, Yu FF, Yin XR, Zhao YF, Ye F, Wu XQ
Environmental toxicology 2021 Dec;36(12):2367-2379
Environmental toxicology 2021 Dec;36(12):2367-2379
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Chen N, Song S, Yang Z, Wu M, Mu L, Zhou T, Shi Y
Journal of diabetes and its complications 2021 Dec;35(12):108050
Journal of diabetes and its complications 2021 Dec;35(12):108050
The endocytic pathway of Pt nanoclusters and their induced apoptosis of A549 and A549/Cis cells through c-Myc/p53 and Bcl-2/caspase-3 signaling pathways.
Zhao L, Li H, Huang X, Liu T, Xin Y, Xiao Z, Zhao W, Miao S, Chen J, Li Z, Mi Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112360
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112360
Corosolic acid reduces A549 and PC9 cell proliferation, invasion, and chemoresistance in NSCLC via inducing mitochondrial and liposomal oxidative stress.
Jin M, Wu Y, Lou Y, Liu X, Dai Y, Yang W, Liu C, Huang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112313
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112313
The XBP1‒MARCH5‒MFN2 Axis Confers Endoplasmic Reticulum Stress Resistance by Coordinating Mitochondrial Fission and Mitophagy in Melanoma.
Wang H, Yi X, Guo S, Wang S, Ma J, Zhao T, Shi Q, Tian Y, Wang H, Jia L, Gao T, Li C, Guo W
The Journal of investigative dermatology 2021 Dec;141(12):2932-2943.e12
The Journal of investigative dermatology 2021 Dec;141(12):2932-2943.e12
Sequential Epiphyseal Cartilage Changes of Femoral Heads in C57BL/6 Female Mice Treated with Excessive Glucocorticoids.
Jin S, Yang L, Meng C, He Y, Ma K, Huang W, Wang H
Cartilage 2021 Dec;13(2_suppl):453S-464S
Cartilage 2021 Dec;13(2_suppl):453S-464S
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600
Bioengineered 2021 Dec;12(1):589-600
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Ge S, Jiang C, Li M, Cheng Z, Feng X
Cancer cell international 2021 Dec 4;21(1):650
Cancer cell international 2021 Dec 4;21(1):650
Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension.
Ma W, Qiu Z, Bai Z, Dai Y, Li C, Chen X, Song X, Shi D, Zhou Y, Pan Y, Liao Y, Liao M, Zhou Z
Molecular therapy. Nucleic acids 2021 Dec 3;26:678-693
Molecular therapy. Nucleic acids 2021 Dec 3;26:678-693
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Li H, Fan J, Zhao Y, Yang J, Xu H, Manthari RK, Cheng X, Wang J, Wang J
Ecotoxicology and environmental safety 2021 Dec 15;226:112851
Ecotoxicology and environmental safety 2021 Dec 15;226:112851
Recombinant protein Schistosoma japonicum-derived molecule attenuates dextran sulfate sodium-induced colitis by inhibiting miRNA-217-5p to alleviate apoptosis.
Zhang LC, Wu XY, Yang RB, Chen F, Liu JH, Hu YY, Wu ZD, Wang LF, Sun X
World journal of gastroenterology 2021 Dec 14;27(46):7982-7994
World journal of gastroenterology 2021 Dec 14;27(46):7982-7994
TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension.
Cao X, Fang X, Guo M, Li X, He Y, Xie M, Xu Y, Liu X
Respiratory research 2021 Dec 14;22(1):312
Respiratory research 2021 Dec 14;22(1):312
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Zhang Y, Peng X
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Vitamin E regulates bovine granulosa cell apoptosis via NRF2-mediated defence mechanism by activating PI3K/AKT and ERK1/2 signalling pathways.
Wang M, Li Y, Gao Y, Li Q, Cao Y, Shen Y, Chen P, Yan J, Li J
Reproduction in domestic animals = Zuchthygiene 2021 Aug;56(8):1066-1084
Reproduction in domestic animals = Zuchthygiene 2021 Aug;56(8):1066-1084
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway.
Deng H, Yu B, Li Y
Phytotherapy research : PTR 2021 Aug;35(8):4309-4323
Phytotherapy research : PTR 2021 Aug;35(8):4309-4323
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.
Pan S, Zhang Y, Huang M, Deng Z, Zhang A, Pei L, Wang L, Zhao W, Ma L, Zhang Q, Cui D
Biomaterials 2021 Aug;275:120946
Biomaterials 2021 Aug;275:120946
Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.
Zhou X, Zhang T, Song L, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Zhang W, Song N, Wang S
Ecotoxicology and environmental safety 2021 Aug;219:112323
Ecotoxicology and environmental safety 2021 Aug;219:112323
Vitamin E and selenium supplementation synergistically alleviate the injury induced by hydrogen peroxide in bovine granulosa cells.
Wang M, Li Y, Molenaar A, Li Q, Cao Y, Shen Y, Chen P, Yan J, Gao Y, Li J
Theriogenology 2021 Aug;170:91-106
Theriogenology 2021 Aug;170:91-106
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation.
Yang Z, Chen Z, Wang C, Huang P, Luo M, Zhou R
Cytokine 2021 Aug;144:155535
Cytokine 2021 Aug;144:155535
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
Wang HX, Zhang R, Li Z, Wang LS, Yu Y, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
Toxicology research 2021 Aug;10(4):742-750
Toxicology research 2021 Aug;10(4):742-750
Autophagy Delays Apoptotic Cell Death Induced by Siniperca chuatsi Rhabdovirus in Epithelioma Papulosum Cyprinid Cells.
Zhou GZ, Li J, Sun YH, Zhang Q, Zhang L, Pei C
Viruses 2021 Aug 6;13(8)
Viruses 2021 Aug 6;13(8)
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.
Zhou L, Zhang C, Qiang Y, Huang M, Ren X, Li Y, Shao J, Xu L
Ecotoxicology and environmental safety 2021 Aug 24;224:112683
Ecotoxicology and environmental safety 2021 Aug 24;224:112683
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis.
Fu J, Tang Y, Zhang Z, Tong L, Yue R, Cai L
Molecular medicine (Cambridge, Mass.) 2021 Aug 19;27(1):90
Molecular medicine (Cambridge, Mass.) 2021 Aug 19;27(1):90
Transcriptome Analysis Reveals the Potential Role of Long Noncoding RNAs in Regulating Fowl Adenovirus Serotype 4-Induced Apoptosis in Leghorn Male Hepatocellular Cells.
Wen B, Wang X, Yang L, Wang T, Hou X, Qi X, Wang J
Viruses 2021 Aug 17;13(8)
Viruses 2021 Aug 17;13(8)
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation.
Wu F, Shao Q, Cheng Z, Xiong X, Fang K, Zhao Y, Dong R, Xu L, Lu F, Chen G
Chinese medicine 2021 Aug 16;16(1):78
Chinese medicine 2021 Aug 16;16(1):78
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Xiaoli F, Yaqing Z, Ruhui L, Xuan L, Aijie C, Yanli Z, Chen H, Lili C, Longquan S
Journal of hazardous materials 2021 Aug 15;416:126158
Journal of hazardous materials 2021 Aug 15;416:126158
Targeting hypoxia for sensitization of tumors to apoptosis enhancement through supramolecular biohybrid bacteria.
Wu Y, Li Q, Liu Y, Li Y, Chen Y, Wu X, Liu X
International journal of pharmaceutics 2021 Aug 10;605:120817
International journal of pharmaceutics 2021 Aug 10;605:120817
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells.
Xiao M, Tang N, Yan Y, Li Z, Shi S, He S, Chen Z, Cao K, Chen J, Zhou J, Chen X
Melanoma research 2021 Aug 1;31(4):309-318
Melanoma research 2021 Aug 1;31(4):309-318
NCX3 alleviates ethanol-induced apoptosis of SK-N-SH cells via the elimination of intracellular calcium ions.
Xia Z, Wang C, Wang X, Yu H, Yao H, Shen H, Lan X, Wu X, Zhang G
Toxicology in vitro : an international journal published in association with BIBRA 2021 Apr;72:105104
Toxicology in vitro : an international journal published in association with BIBRA 2021 Apr;72:105104
Resveratrol-induced apoptosis is associated with regulating the miR-492/CD147 pathway in malignant melanoma cells.
Zhao S, Tang L, Chen W, Su J, Li F, Chen X, Wu L
Naunyn-Schmiedeberg's archives of pharmacology 2021 Apr;394(4):797-807
Naunyn-Schmiedeberg's archives of pharmacology 2021 Apr;394(4):797-807
Coaction of hepatic thioredoxin and glutathione systems in iron overload-induced oxidative stress.
Sönmez Aydın F, Hukkamlı B, Budak H
Journal of biochemical and molecular toxicology 2021 Apr;35(4):e22704
Journal of biochemical and molecular toxicology 2021 Apr;35(4):e22704
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Liu X, Gu Y, Bian Y, Cai D, Li Y, Zhao Y, Zhang Z, Xue M, Zhang L
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Exosomal miR-27 negatively regulates ROS production and promotes granulosa cells apoptosis by targeting SPRY2 in OHSS.
Liu K, Yang W, Hu M, Xie W, Huang J, Cui M, He X, Nie X
Journal of cellular and molecular medicine 2021 Apr;25(8):3976-3990
Journal of cellular and molecular medicine 2021 Apr;25(8):3976-3990
PBK promotes aggressive phenotypes of cervical cancer through ERK/c-Myc signaling pathway.
Ma H, Han F, Yan X, Qi G, Li Y, Li R, Yan S, Yuan C, Song K, Kong B
Journal of cellular physiology 2021 Apr;236(4):2767-2781
Journal of cellular physiology 2021 Apr;236(4):2767-2781
Morroniside protects OLN-93 cells against H(2)O(2)-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities.
Li F, Song X, Xu J, Shi Y, Hu R, Ren Z, Qi Q, Lü H, Cheng X, Hu J
Cell cycle (Georgetown, Tex.) 2021 Apr;20(7):661-675
Cell cycle (Georgetown, Tex.) 2021 Apr;20(7):661-675
Abnormal Glu/mGluR(2/3)/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Liu J, Han YS, Liu L, Tang L, Yang H, Meng P, Zhao HQ, Wang YH
Neural regeneration research 2021 Apr;16(4):727-733
Neural regeneration research 2021 Apr;16(4):727-733
Dracomolphin A-E, new lignans from Dracocephalum moldavica.
Zhang H, Wang S, Liu Q, Zheng H, Liu X, Wang X, Shen T, Ren D
Fitoterapia 2021 Apr;150:104841
Fitoterapia 2021 Apr;150:104841
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Yan F, Liu R, Zhuang X, Li R, Shi H, Gao X
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.
Zhang X, Feng C, Wang S, Wang Y, Fu Z, Zhang Y, Sun H, Xie C, Fu Y, Tao J, Luo M, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111258
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111258
Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase.
Wang ZD, Feng Y, Sun L, Gan J, Li X, Ding WF, Chen XM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111241
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111241
The Crosstalk between Autophagy and Apoptosis Is Necessary for Myogenic Differentiation.
Jiang A, Guo H, Wu W, Liu H
Journal of agricultural and food chemistry 2021 Apr 7;69(13):3942-3951
Journal of agricultural and food chemistry 2021 Apr 7;69(13):3942-3951
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
Zhou Z, Xie J, Ma S, Luo X, Liu J, Wang S, Chen Y, Yan J, Luo F
ACS omega 2021 Apr 27;6(16):10723-10734
ACS omega 2021 Apr 27;6(16):10723-10734
A Bioinformatics Analysis Identifies the Telomerase Inhibitor MST-312 for Treating High-STMN1-Expressing Hepatocellular Carcinoma.
Wang SJ, Yang PM
Journal of personalized medicine 2021 Apr 22;11(5)
Journal of personalized medicine 2021 Apr 22;11(5)
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Xie Q, Liu Y, Long Y, Wang Z, Jiang S, Ahmed R, Daniyal M, Li B, Liu B, Wang W
Biomaterials science 2021 Apr 21;9(8):2991-3004
Biomaterials science 2021 Apr 21;9(8):2991-3004
Grape seed proanthocyanidins protect PC12 cells from hydrogen peroxide-induced damage via the PI3K/AKT signaling pathway.
He X, Guo X, Ma Z, Li Y, Kang J, Zhang G, Gao Y, Liu M, Chen H, Kang X
Neuroscience letters 2021 Apr 17;750:135793
Neuroscience letters 2021 Apr 17;750:135793
Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis.
Wei H, Qu L, Dai S, Li Y, Wang H, Feng Y, Chen X, Jiang L, Guo M, Li J, Chen Z, Chen L, Zhang Y, Chen Y
Nature communications 2021 Apr 16;12(1):2280
Nature communications 2021 Apr 16;12(1):2280
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Wang F, Wang L, Qu C, Chen L, Geng Y, Cheng C, Yu S, Wang D, Yang L, Meng Z, Chen Z
BMC cancer 2021 Apr 12;21(1):396
BMC cancer 2021 Apr 12;21(1):396
Inhibiting Heat Shock Protein 90 Protects Nucleus Pulposus-Derived Stem/Progenitor Cells From Compression-Induced Necroptosis and Apoptosis.
Hu B, Zhang S, Liu W, Wang P, Chen S, Lv X, Shi D, Ma K, Wang B, Wu Y, Shao Z
Frontiers in cell and developmental biology 2020;8:685
Frontiers in cell and developmental biology 2020;8:685
Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression.
Wang P, Lan R, Guo Z, Cai S, Wang J, Wang Q, Li Z, Li Z, Wang Q, Li J, Wu Z, Lu J, Liu P
Frontiers in cell and developmental biology 2020;8:548605
Frontiers in cell and developmental biology 2020;8:548605
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
Li J, Yang Q, Han L, Pan C, Lei C, Chen H, Lan X
Frontiers in cell and developmental biology 2020;8:541260
Frontiers in cell and developmental biology 2020;8:541260
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Cui Y, Chen R, Ma L, Yang W, Chen M, Zhang Y, Yu S, Dong W, Zeng W, Lan X, Pan C
Frontiers in cell and developmental biology 2020;8:448
Frontiers in cell and developmental biology 2020;8:448
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Clinics (Sao Paulo, Brazil) 2020;75:e1865
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α.
Tang BI, Tang MM, Xu QM, Guo JL, Xuan L, Zhou J, Wang XJ, Zhang H, Kang PF
Journal of biosciences 2020;45
Journal of biosciences 2020;45
Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway.
Sun Y, Chen Y, Xu M, Liu C, Shang H, Wang C
BioMed research international 2020;2020:9243681
BioMed research international 2020;2020:9243681
Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors.
Zhang X, Yang Y, Yang Y, Chen H, Tu H, Li J
Stem cells international 2020;2020:8890201
Stem cells international 2020;2020:8890201
Metabolomic Analysis of the Ameliorative Effect of Enhanced Proline Metabolism on Hypoxia-Induced Injury in Cardiomyocytes.
Wang J, Xue Z, Hua C, Lin J, Shen Z, Song Y, Ying H, Lv Q, Wang M, Zhou B
Oxidative medicine and cellular longevity 2020;2020:8866946
Oxidative medicine and cellular longevity 2020;2020:8866946
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Chen S, Wang Y, Liao L, Meng L, Li J, Shi C, Han H, Zheng X, Shen H
Stem cells international 2020;2020:8861557
Stem cells international 2020;2020:8861557
TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways.
Meng X, Zhang C, Guo Y, Han Y, Wang C, Chu H, Kong L, Ma H
Oxidative medicine and cellular longevity 2020;2020:8787156
Oxidative medicine and cellular longevity 2020;2020:8787156
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Cui G, Li L, Xu W, Wang M, Jiao D, Yao B, Xu K, Chen Y, Yang S, Long M, Li P, Guo Y
Oxidative medicine and cellular longevity 2020;2020:7639109
Oxidative medicine and cellular longevity 2020;2020:7639109
Neuroprotective Effect of the Inhibitor Salubrinal after Cardiac Arrest in a Rodent Model.
Zhang J, Wang Y, Ju M, Song J, Zheng Y, Lin S, Zhu D, Wen L, Zhong M, Pan S, Yang G
Oxidative medicine and cellular longevity 2020;2020:7468738
Oxidative medicine and cellular longevity 2020;2020:7468738
Experimental Study on the Effect of Aconite and Angelica sinensis on Myocardial Ischemia Rats with Yang Deficiency and Blood Stasis.
Cao Y, Liang X, Li C, Chen T, Li Z, Li W, Liu P, Li G, Ma R, Tang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7027391
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7027391
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236
Oxidative medicine and cellular longevity 2020;2020:6834236
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Wang CH, Yang JM, Guo YB, Shen J, Pei XH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats.
Li S, Dong J, Ta G, Liu Y, Cui J, Li X, Song J, Liu A, Cheng G
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5041629
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5041629
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Deng X, Lin N, Fu J, Xu L, Luo H, Jin Y, Liu Y, Sun L, Su J
Oxidative medicine and cellular longevity 2020;2020:4830418
Oxidative medicine and cellular longevity 2020;2020:4830418
Antitumor Effects of Curcumin and Glycyrrhetinic Acid-Modified Curcumin-Loaded Cationic Liposome by Intratumoral Administration.
Chang M, Wu M, Li H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4504936
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4504936
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Almoiliqy M, Wen J, Qaed E, Sun Y, Lian M, Mousa H, Al-Azab M, Zaky MY, Chen D, Wang L, Al-Sharabi A, Liu Z, Sun P, Lin Y
Oxidative medicine and cellular longevity 2020;2020:4196548
Oxidative medicine and cellular longevity 2020;2020:4196548
Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway.
Du LJ, Pang B, Tan YM, Yang YN, Zhang MZ, Pang Q, Sun M, Ni Q
Journal of diabetes research 2020;2020:3695689
Journal of diabetes research 2020;2020:3695689
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Deng LH, Li L, Zhai Y, Michael S, Yang CY, Guo R, Chen SF, Fan GW, Zhao YQ, Liu W
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191
miR193b Promotes Apoptosis of Gastric Cancer Cells via Directly Mediating the Akt Pathway.
Tian R, Jiang H, Shao L, Yu Y, Guo Q, Cao B, Guo S
BioMed research international 2020;2020:2863236
BioMed research international 2020;2020:2863236
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
Guo LP, Liu SX, Yang Q, Liu HY, Xu LL, Hao YH, Zhang XQ
BioMed research international 2020;2020:1594726
BioMed research international 2020;2020:1594726
The Protective Effect of Adiponectin-Transfected Endothelial Progenitor Cells on Cognitive Function in D-Galactose-Induced Aging Rats.
Huang J, Hou B, Zhang S, Wang M, Lu X, Wang Q, Liu Y
Neural plasticity 2020;2020:1273198
Neural plasticity 2020;2020:1273198
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Li C, Wang X, Yan J, Cheng F, Ma X, Chen C, Wang W, Wang Q
Oxidative medicine and cellular longevity 2020;2020:1201624
Oxidative medicine and cellular longevity 2020;2020:1201624
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
Li L, Li X, Zhang Z, Liu L, Liu T, Li S, Liu S, Zhou Y, Liu F
Current molecular medicine 2020;20(5):396-406
Current molecular medicine 2020;20(5):396-406
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b.
Wang W, Wang M, Xu J, Long F, Zhan X
Cancer cell international 2020;20:339
Cancer cell international 2020;20:339
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity.
Lv S, Ju C, Peng J, Liang M, Zhu F, Wang C, Huang K, Cheng M, Zhang F
International journal of biological sciences 2020;16(2):298-308
International journal of biological sciences 2020;16(2):298-308
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
Nakano D, Kawaguchi T, Iwamoto H, Hayakawa M, Koga H, Torimura T
PloS one 2020;15(4):e0232283
PloS one 2020;15(4):e0232283
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Lin HY, Han HW, Wang YS, He DL, Sun WX, Feng L, Wen ZL, Yang MK, Lu GH, Wang XM, Qi JL, Yang YH
Chinese medicine 2020;15:23
Chinese medicine 2020;15:23
Liquiritigenin-Loaded Submicron Emulsion Protects Against Doxorubicin-Induced Cardiotoxicity via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activity.
Shi C, Wu H, Xu K, Cai T, Qin K, Wu L, Cai B
International journal of nanomedicine 2020;15:1101-1115
International journal of nanomedicine 2020;15:1101-1115
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
Zhang X, Chen Y, Wang K, Tang J, Chen Y, Jin G, Liu X
International journal of clinical and experimental pathology 2020;13(9):2228-2239
International journal of clinical and experimental pathology 2020;13(9):2228-2239
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
Hu X, Wang J, Chai J, Yu X, Zhang Y, Feng Y, Qin J, Yu H
OncoTargets and therapy 2020;13:9967-9976
OncoTargets and therapy 2020;13:9967-9976
Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway.
Fan J, Tian L, Huang S, Zhang J, Zhao B
OncoTargets and therapy 2020;13:5407-5417
OncoTargets and therapy 2020;13:5407-5417
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib.
Yang S, Wang M, Yang L, Li Y, Ma Y, Peng X, Li X, Li B, Jin H, Li H
OncoTargets and therapy 2020;13:3557-3570
OncoTargets and therapy 2020;13:3557-3570
Chronic Unpredictable Mild Stress Accelerates the Growth of Bladder Cancer in a Xenograft Mouse Model.
Zhou Q, Ding W, Qian Z, Jiang G, Sun C, Xu K
Psychology research and behavior management 2020;13:1289-1297
Psychology research and behavior management 2020;13:1289-1297
Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery.
Zhao S, Xiao P, Cui H, Gong P, Lin C, Chen F, Tang Z
Frontiers in molecular neuroscience 2020;13:100
Frontiers in molecular neuroscience 2020;13:100
Deubiquitinase PSMD7 regulates cell fate and is associated with disease progression in breast cancer.
Zhao Y, Yang X, Xu X, Zhang J, Zhang L, Xu H, Miao Z, Li D, Wang S
American journal of translational research 2020;12(9):5433-5448
American journal of translational research 2020;12(9):5433-5448
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
He C, Xia J, Gao Y, Chen Z, Wan X
American journal of translational research 2020;12(9):5080-5094
American journal of translational research 2020;12(9):5080-5094
Long non-coding RNA KRT16P2/miR-1294/EGFR axis regulates laryngeal squamous cell carcinoma cell aggressiveness.
Yang T, Li S, Liu J, Yin D, Yang X, Tang Q, Wang S
American journal of translational research 2020;12(6):2939-2955
American journal of translational research 2020;12(6):2939-2955
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
Chu P, Wang S, Zhu X, Yang Y, Li H, Tesfaldet T, Shopit A, Yang Y, Ma X, Peng J, Tang Z, Sun Z
American journal of translational research 2020;12(11):7127-7143
American journal of translational research 2020;12(11):7127-7143
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
Jing X, Chen Y, Chen Y, Shi G, Lv S, Cheng N, Feng C, Xin Z, Zhang L, Wu J
Cancer management and research 2020;12:2185-2194
Cancer management and research 2020;12:2185-2194
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP
Cancer management and research 2020;12:1789-1798
Cancer management and research 2020;12:1789-1798
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
Wang Z, Li F, Wei M, Zhang S, Wang T
Cancer management and research 2020;12:11897-11908
Cancer management and research 2020;12:11897-11908
Baohuoside I via mTOR Apoptotic Signaling to Inhibit Glioma Cell Growth.
Guo Y, Wang C, Jiang M, Zhu H, Weng M, Sun L, Zhang Y
Cancer management and research 2020;12:11435-11444
Cancer management and research 2020;12:11435-11444
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.
Yu J, Wang W, Yao W, Yang Z, Gao P, Liu M, Wang H, Chen S, Wang D, Wang W, Sun G
Journal of Cancer 2020;11(19):5568-5577
Journal of Cancer 2020;11(19):5568-5577
Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance.
Zhang L, Xu H, Ma C, Zhang J, Zhao Y, Yang X, Wang S, Li D
Journal of Cancer 2020;11(10):2962-2971
Journal of Cancer 2020;11(10):2962-2971
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Shi J, Xiao P, Liu X, Chen Y, Xu Y, Fan J, Yin Y
Frontiers in physiology 2020;11:669
Frontiers in physiology 2020;11:669
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Li B, Chen Z, Luo X, Zhang C, Chen H, Wang S, Zhao M, Ma H, Liu J, Cheng M, Yang Y, Yan H
Frontiers in pharmacology 2020;11:612932
Frontiers in pharmacology 2020;11:612932
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Wang H, Xia W, Long G, Pei Z, Li Y, Wu M, Wang Q, Zhang Y, Jia Z, Chen H
Frontiers in pharmacology 2020;11:599416
Frontiers in pharmacology 2020;11:599416
Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.
Wu D, Zhong P, Wang Y, Zhang Q, Li J, Liu Z, Ji A, Li Y
Frontiers in pharmacology 2020;11:585860
Frontiers in pharmacology 2020;11:585860
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Zhang S, Feng Z, Gao W, Duan Y, Fan G, Geng X, Wu B, Li K, Liu K, Peng C
Frontiers in pharmacology 2020;11:544124
Frontiers in pharmacology 2020;11:544124
Morroniside Inhibits H(2)O(2)-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Gao X, Liu Y, Wang L, Sai N, Liu Y, Ni J
Frontiers in pharmacology 2020;11:533809
Frontiers in pharmacology 2020;11:533809
miR-149-5p Regulates Goat Hair Follicle Stem Cell Proliferation and Apoptosis by Targeting the CMTM3/AR Axis During Superior-Quality Brush Hair Formation.
Wang J, Qu J, Li Y, Feng Y, Ma J, Zhang L, Chu C, Hu H, Wang Y, Ji D
Frontiers in genetics 2020;11:529757
Frontiers in genetics 2020;11:529757
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4(+) and CD8(+) T Cells During BVDV Infection in vitro.
Liu Y, Liu S, Wu C, Huang W, Xu B, Lian S, Wang L, Yue S, Chen N, Zhu Z
Frontiers in immunology 2020;11:467
Frontiers in immunology 2020;11:467
α-Cyperone Attenuates H(2)O(2)-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2.
Huang B, Liu J, Fu S, Zhang Y, Li Y, He D, Ran X, Yan X, Du J, Meng T, Gao X, Liu D
Frontiers in pharmacology 2020;11:281
Frontiers in pharmacology 2020;11:281
Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling.
Liu D, Bai X, Ma W, Xin D, Chu X, Yuan H, Qiu J, Ke H, Yin S, Chen W, Wang Z
Frontiers in pharmacology 2020;11:204
Frontiers in pharmacology 2020;11:204
Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.
Su W, Zhao J, Fan TJ
Frontiers in pharmacology 2020;11:202
Frontiers in pharmacology 2020;11:202
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Yan Z, Zhan J, Qi W, Lin J, Huang Y, Xue X, Pan X
Frontiers in pharmacology 2020;11:1195
Frontiers in pharmacology 2020;11:1195
Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy.
Ye J, Lu S, Wang M, Ge W, Liu H, Qi Y, Fu J, Zhang Q, Zhang B, Sun G, Sun X
Frontiers in pharmacology 2020;11:1170
Frontiers in pharmacology 2020;11:1170
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Gao L, Liu J, Xu P, Deng G, Liu B, Yuan F, Tan Y, Sun Q, Xu Y, Zhang H, Qi Y, Han S, Yang K, Geng R, Jiang H, Chen Q
Frontiers in pharmacology 2020;11:1102
Frontiers in pharmacology 2020;11:1102
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis.
Zhang H, Tian F, Jiang P, Qian S, Dai X, Ma B, Wang M, Dai H, Sha X, Yang Z, Zhu X, Sun X
Frontiers in oncology 2020;10:614067
Frontiers in oncology 2020;10:614067
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Zhou B, Yang C, Yan X, Shi Z, Xiao H, Wei X, Jiang N, Wu Z
Frontiers in oncology 2020;10:606790
Frontiers in oncology 2020;10:606790
Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells.
Fang X, Tan T, Gao B, Zhao Y, Liu T, Xia Q
Frontiers in oncology 2020;10:537322
Frontiers in oncology 2020;10:537322
Combination Therapy of Prostate Cancer by Oncolytic Adenovirus Harboring Interleukin 24 and Ionizing Radiation.
Mao LJ, Kan Y, Li BH, Ma S, Liu Y, Yang DL, Yang C
Frontiers in oncology 2020;10:421
Frontiers in oncology 2020;10:421
Caspase-3 inhibitor inhibits enterovirus D68 production.
Huo W, Yu J, Liu C, Wu T, Wang Y, Meng X, Song F, Zhang S, Su Y, Liu Y, Liu J, Yu X, Hua S
Journal of microbiology (Seoul, Korea) 2020 Sep;58(9):812-820
Journal of microbiology (Seoul, Korea) 2020 Sep;58(9):812-820
Apigetrin ameliorates streptozotocin-induced pancreatic β-cell damages via attenuating endoplasmic reticulum stress.
Zhang R, Shi J, Wang T, Qiu X, Liu R, Li Y, Gao Q, Wang N
In vitro cellular & developmental biology. Animal 2020 Sep;56(8):622-634
In vitro cellular & developmental biology. Animal 2020 Sep;56(8):622-634
Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma.
An K, Zhang Y, Liu Y, Yan S, Hou Z, Cao M, Liu G, Dong C, Gao J, Liu G
Oncology reports 2020 Sep;44(3):1116-1126
Oncology reports 2020 Sep;44(3):1116-1126
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Almoiliqy M, Wen J, Xu B, Sun YC, Lian MQ, Li YL, Qaed E, Al-Azab M, Chen DP, Shopit A, Wang L, Sun PY, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
Zhang N, Zhang Y, Qian H, Wu S, Cao L, Sun Y
Cell death and differentiation 2020 Sep;27(9):2605-2619
Cell death and differentiation 2020 Sep;27(9):2605-2619
A novel antisense lncRNA NT5E promotes progression by modulating the expression of SYNCRIP and predicts a poor prognosis in pancreatic cancer.
Zhang P, Cao M, Zhang Y, Xu L, Meng F, Wu X, Xia T, Chen Q, Shi G, Wu P, Chen L, Lu Z, Yin J, Cai B, Cao S, Miao Y, Jiang K
Journal of cellular and molecular medicine 2020 Sep;24(18):10898-10912
Journal of cellular and molecular medicine 2020 Sep;24(18):10898-10912
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
Liu W, Zhou J, Niu F, Pu F, Wang Z, Huang M, Zhao X, Yang L, Tao P, Xia P, Feng J
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, Sun Y, Su J, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397
Valproic acid overcomes sorafenib resistance by reducing the migration of Jagged2-mediated Notch1 signaling pathway in hepatocellular carcinoma cells.
Liu J, Yang X, Liang Q, Yu Y, Shen X, Sun G
The international journal of biochemistry & cell biology 2020 Sep;126:105820
The international journal of biochemistry & cell biology 2020 Sep;126:105820
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359
Journal of dairy science 2020 Sep;103(9):8350-8359
Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers.
Wu Q, Song Y, Liu R, Wang R, Mei W, Chen W, Yang H, Wang X
Bioorganic chemistry 2020 Sep;102:104074
Bioorganic chemistry 2020 Sep;102:104074
Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele.
Xu YW, Ou NJ, Song YX, Wang XH, Kang JQ, Yang YJ, Chen YG, Liu XQ
Asian journal of andrology 2020 Sep-Oct;22(5):513-518
Asian journal of andrology 2020 Sep-Oct;22(5):513-518
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Ma M, Zhang J, Gao X, Yao W, Li Q, Pan Z
Biomolecules 2020 Sep 4;10(9)
Biomolecules 2020 Sep 4;10(9)
MiR-489 aggravates H2O2-induced apoptosis of cardiomyocytes via inhibiting IGF1.
Tang S, Zhong H, Xiong T, Yang X, Mao Y, Wang D
Bioscience reports 2020 Sep 30;40(9)
Bioscience reports 2020 Sep 30;40(9)
Globular CTRP9 protects cardiomyocytes from palmitic acid-induced oxidative stress by enhancing autophagic flux.
Zuo A, Li J, Zhao X, Li T, Lei S, Chen J, Xu D, Song C, Li N, Ruan S, Lyu L, Guo Y
Chemico-biological interactions 2020 Sep 25;329:109094
Chemico-biological interactions 2020 Sep 25;329:109094
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Jiang TY, Pan YF, Wan ZH, Lin YK, Zhu B, Yuan ZG, Ma YH, Shi YY, Zeng TM, Dong LW, Tan YX, Wang HY
Science translational medicine 2020 Sep 23;12(562)
Science translational medicine 2020 Sep 23;12(562)
Protective effects of alfalfa saponins on oxidative stress-induced apoptotic cells.
Cui Y, Liu B, Sun X, Li Z, Chen Y, Guo Z, Liu H, Li D, Wang C, Zhu X, Shi Y
Food & function 2020 Sep 23;11(9):8133-8140
Food & function 2020 Sep 23;11(9):8133-8140
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Liu J, Deng X, Sun X, Dong J, Huang J
Life sciences 2020 Sep 15;257:118040
Life sciences 2020 Sep 15;257:118040
Sphingomyelin Synthase 2 Participate in the Regulation of Sperm Motility and Apoptosis.
Li X, Luo T, Li H, Yan N
Molecules (Basel, Switzerland) 2020 Sep 15;25(18)
Molecules (Basel, Switzerland) 2020 Sep 15;25(18)
Involvement of JNK/FOXO1 pathway in apoptosis induced by severe hypoxia in porcine granulosa cells.
Liu Z, Li C, Wu G, Li W, Zhang X, Zhou J, Zhang L, Tao J, Shen M, Liu H
Theriogenology 2020 Sep 15;154:120-127
Theriogenology 2020 Sep 15;154:120-127
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, Wang C, Chen J, Liu Y, Machens HG, Chen Z
Life sciences 2020 Sep 1;256:118022
Life sciences 2020 Sep 1;256:118022
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, Bai X, Liu D, Wang Z
Acta biomaterialia 2020 Sep 1;113:597-613
Acta biomaterialia 2020 Sep 1;113:597-613
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Liu A, Zuo Z, Liu L, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.
Zhou B, Peng K, Wang G, Chen W, Liu P, Chen F, Kang Y
International journal of molecular medicine 2020 Oct;46(4):1571-1581
International journal of molecular medicine 2020 Oct;46(4):1571-1581
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
Wu S, Zhang X, Dong M, Yang Z, Zhang M, Chen Q
Oncology reports 2020 Oct;44(4):1467-1478
Oncology reports 2020 Oct;44(4):1467-1478
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
Yang ZH, Li J, Chen WZ, Kong FS
Cell biochemistry and function 2020 Oct;38(7):943-954
Cell biochemistry and function 2020 Oct;38(7):943-954
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Li Y, Zhang M, Li F
Histology and histopathology 2020 Oct;35(10):1171-1180
Histology and histopathology 2020 Oct;35(10):1171-1180
Proanthocyanidin B2 inhibits proliferation and induces apoptosis of osteosarcoma cells by suppressing the PI3K/AKT pathway.
Wu X, Yu H, Zhou H, Li Z, Huang H, Xiao F, Xu S, Yang Y
Journal of cellular and molecular medicine 2020 Oct;24(20):11960-11971
Journal of cellular and molecular medicine 2020 Oct;24(20):11960-11971
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
Potential hazardous effects of printing room PM2.5 exposure include promotion of lung inflammation and subsequent injury.
Zou C, Yang H, Cui L, Cao X, Huang H, Chen T
Molecular medicine reports 2020 Oct;22(4):3213-3224
Molecular medicine reports 2020 Oct;22(4):3213-3224
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Inhibitory effect of Lycium barbarum polysaccharide on sperm damage during cryopreservation.
Yan B, Zhang X, Wang J, Jia S, Zhou Y, Tian J, Wang H, Tang Y
Experimental and therapeutic medicine 2020 Oct;20(4):3051-3063
Experimental and therapeutic medicine 2020 Oct;20(4):3051-3063
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
Yu X, Li H, Zhu M, Hu P, Liu X, Qing Y, Wang X, Wang H, Wang Z, Xu J, Tan R, Guo Q, Hui H
The Journal of investigative dermatology 2020 Oct;140(10):2009-2022.e4
The Journal of investigative dermatology 2020 Oct;140(10):2009-2022.e4
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y
Nanotoxicology 2020 Oct;14(8):1017-1038
Nanotoxicology 2020 Oct;14(8):1017-1038
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
Zhang S, Wang S, Shi X, Feng X
Neurochemistry international 2020 Oct;139:104815
Neurochemistry international 2020 Oct;139:104815
S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.
Shao Z, Pan Z, Lin J, Zhao Q, Wang Y, Ni L, Feng S, Tian N, Wu Y, Sun L, Gao W, Zhou Y, Zhang X, Wang X
Aging 2020 Oct 7;12(19):19254-19272
Aging 2020 Oct 7;12(19):19254-19272
Effect of Zhenxin Xingshui Yizhi Fang on Aβ(25-35) induced expression of related transporters in HBMEC cell model.
Wu L, Zheng Q, Guo YY, Zhang KN, Luo J, Xiao S, Li WJ, Yang M
Journal of ethnopharmacology 2020 Oct 5;260:112783
Journal of ethnopharmacology 2020 Oct 5;260:112783
Activation of Sirtuin1 by lyceum barbarum polysaccharides in protection against diabetic cataract.
Yao Q, Zhou Y, Yang Y, Cai L, Xu L, Han X, Guo Y, Li PA
Journal of ethnopharmacology 2020 Oct 28;261:113165
Journal of ethnopharmacology 2020 Oct 28;261:113165
Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wei Z, Nie G, Yang F, Pi S, Wang C, Cao H, Guo X, Liu P, Li G, Hu G, Zhang C
Environmental pollution (Barking, Essex : 1987) 2020 Oct 23;273:115919
Environmental pollution (Barking, Essex : 1987) 2020 Oct 23;273:115919
Cortistatin protects against inflammatory airway diseases through curbing CCL2 and antagonizing NF-κB signaling pathway.
Qiu C, Li J, Luo D, Chen X, Qu R, Liu T, Li F, Liu Y
Biochemical and biophysical research communications 2020 Oct 22;531(4):595-601
Biochemical and biophysical research communications 2020 Oct 22;531(4):595-601
Loss of RAD6B induces degeneration of the cochlea in mice.
Ma Y, Song Y, Shen R, Li P, Ding H, Guo Z, Liu X, Wang D
Biochemical and biophysical research communications 2020 Oct 20;531(3):402-408
Biochemical and biophysical research communications 2020 Oct 20;531(3):402-408
NO66 overexpression rescues ethanol-induced cell apoptosis in human AC16 cardiomyocytes by suppressing PTEN and activating the PI3K/Akt signaling.
Deng H, Yu B, Yu Y, Tian G, Yang L
Acta biochimica et biophysica Sinica 2020 Oct 19;52(10):1093-1101
Acta biochimica et biophysica Sinica 2020 Oct 19;52(10):1093-1101
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice.
Zhao J, Xie C, Wang K, Takahashi S, Krausz KW, Lu D, Wang Q, Luo Y, Gong X, Mu X, Wang Q, Su S, Gonzalez FJ
Toxicology letters 2020 Oct 15;333:290-302
Toxicology letters 2020 Oct 15;333:290-302
Hypoxia Protects Rat Bone Marrow Mesenchymal Stem Cells Against Compression-Induced Apoptosis in the Degenerative Disc Microenvironment Through Activation of the HIF-1α/YAP Signaling Pathway.
Wang Z, Cui M, Qu Y, He R, Wu W, Lin H, Shao Z
Stem cells and development 2020 Oct 15;29(20):1309-1319
Stem cells and development 2020 Oct 15;29(20):1309-1319
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Cheng H, Wu X, Ni G, Wang S, Peng W, Zhang H, Gao J, Li X
Annals of translational medicine 2020 Nov;8(21):1396
Annals of translational medicine 2020 Nov;8(21):1396
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats.
Li M, Liu P, Xue Y, Liang Y, Shi J, Han X, Zhang J, Chu X, Chu L
Oncology reports 2020 Nov;44(5):2306-2316
Oncology reports 2020 Nov;44(5):2306-2316
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
Zhang JX, Qin MB, Ye Z, Peng P, Li SM, Song Q, Lin L, Liu SQ, Xie LH, Zhu Y, Huang JA
Oncology reports 2020 Nov;44(5):2174-2184
Oncology reports 2020 Nov;44(5):2174-2184
ITCH regulates oxidative stress induced by high glucose through thioredoxin interacting protein in cultured human lens epithelial cells.
Jiang L, Zhou W, Lu B, Yan Q
Molecular medicine reports 2020 Nov;22(5):4307-4319
Molecular medicine reports 2020 Nov;22(5):4307-4319
Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.
Wang X, Zhou J, Yang J, Wang S, Yang L
Experimental and therapeutic medicine 2020 Nov;20(5):115
Experimental and therapeutic medicine 2020 Nov;20(5):115
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
Wei J, Yu W, Hao R, Fan J, Gao J
Chemistry & biodiversity 2020 Nov;17(11):e2000654
Chemistry & biodiversity 2020 Nov;17(11):e2000654
Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells.
Jin C, Zhong Y, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111740
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111740
Ghrelin mitigates MPP(+)-induced cytotoxicity: Involvement of ERK1/2-mediated Nrf2/HO-1 and endoplasmic reticulum stress PERK signaling pathway.
Wang H, Dou S, Zhu J, Shao Z, Wang C, Cheng B
Peptides 2020 Nov;133:170374
Peptides 2020 Nov;133:170374
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway.
Li T, Zhang L, Jin C, Xiong Y, Cheng YY, Chen K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110769
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110769
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Liang Y, Zheng B, Li J, Shi J, Chu L, Han X, Chu X, Zhang X, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713
Functionalized graphene oxide against U251 glioma cells and its molecular mechanism.
Wang P, Wang X, Tang Q, Chen H, Zhang Q, Jiang H, Wang Z
Materials science & engineering. C, Materials for biological applications 2020 Nov;116:111187
Materials science & engineering. C, Materials for biological applications 2020 Nov;116:111187
Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2.
Xu B, Zang SC, Lang LM, Lian S, Lu J, Li SZ, Yang HM, Zhen L
Journal of animal physiology and animal nutrition 2020 Nov;104(6):1948-1959
Journal of animal physiology and animal nutrition 2020 Nov;104(6):1948-1959
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Liu Y, Zhou M, Xu S, Khan MA, Shi Y, Qu W, Gao J, Liu G, Kastelic JP, Han B
Journal of dairy science 2020 Nov;103(11):10429-10445
Journal of dairy science 2020 Nov;103(11):10429-10445
Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.
Zheng B, Shi C, Muhammed FK, He J, Abdullah AO, Liu Y
FEBS open bio 2020 Nov;10(11):2404-2416
FEBS open bio 2020 Nov;10(11):2404-2416
Swine MicroRNAs ssc-miR-221-3p and ssc-miR-222 Restrict the Cross-Species Infection of Avian Influenza Virus.
Song J, Sun H, Sun H, Jiang Z, Zhu J, Wang C, Gao W, Wang T, Pu J, Sun Y, Yuan HY, Liu J
Journal of virology 2020 Nov 9;94(23)
Journal of virology 2020 Nov 9;94(23)
Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway.
Yuan J, Zhang G, Li X, Ma Q, Cheng W, Wang W, Zhang B, Hu T, Song G
International journal of molecular sciences 2020 Nov 25;21(23)
International journal of molecular sciences 2020 Nov 25;21(23)
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Ding S, Ma N, Liu H, Tang M, Mei J
Aging 2020 Nov 24;12(24):25505-25527
Aging 2020 Nov 24;12(24):25505-25527
Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Chen Y, Yan Q, Lv M, Song K, Dai Y, Huang Y, Zhang L, Zhang C, Gao H
Cell death & disease 2020 Nov 20;11(11):994
Cell death & disease 2020 Nov 20;11(11):994
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
Wang M, Dong Y, Wu J, Li H, Zhang Y, Fan S, Li D
Life sciences 2020 Nov 15;261:118463
Life sciences 2020 Nov 15;261:118463
Hesperidin ameliorates hypobaric hypoxia-induced retinal impairment through activation of Nrf2/HO-1 pathway and inhibition of apoptosis.
Xin X, Li Y, Liu H
Scientific reports 2020 Nov 10;10(1):19426
Scientific reports 2020 Nov 10;10(1):19426
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Wang J, Liu X, Zheng H, Liu Q, Zhang H, Wang X, Shen T, Wang S, Ren D
Chemico-biological interactions 2020 Nov 1;331:109279
Chemico-biological interactions 2020 Nov 1;331:109279
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413
Life sciences 2020 Nov 1;260:118413
Edaravone attenuates myocyte apoptosis through the JAK2/STAT3 pathway in acute myocardial infarction.
Chen H, Chen Y, Wang X, Yang J, Huang C
Free radical research 2020 May;54(5):351-359
Free radical research 2020 May;54(5):351-359
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
Xu JH, Chen RZ, Liu LY, Li XM, Wu CP, Zhou YT, Yan JD, Zhang ZY
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats.
Liu Y, Chen H, Zhang L, Zhang T, Ren X
Biological trace element research 2020 May;195(1):159-168
Biological trace element research 2020 May;195(1):159-168
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Liu X, Zhang Y, Wu S, Xu M, Shen Y, Yu M, Fan J, Wei S, Xu C, Huang L, Zhao H, Li X, Ye X
Biochemical pharmacology 2020 May;175:113933
Biochemical pharmacology 2020 May;175:113933
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Man S, Yang L, Xiang H, Lu G, Wang Y, Liu C, Gao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109977
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109977
Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2.
Zhou L, Yang C, Zhang N, Zhang X, Zhao T, Yu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109964
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
Zhang X, Wang Y, Liu X, Zhao A, Yang Z, Kong F, Sun L, Yu Y, Jiang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Zhang XM, Wang YZ, Tong JD, Ning XC, Zhou FQ, Yang XH, Jin HM
FEBS open bio 2020 May;10(5):827-834
FEBS open bio 2020 May;10(5):827-834
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Hu Z, Long T, Ma Y, Zhu J, Gao L, Zhong Y, Wang X, Wang X, Li Z
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 May 25;323:109074
Chemico-biological interactions 2020 May 25;323:109074
Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms.
Wang R, Wang S, Chan S, Wang Y, Zhang Y, Zuo Z, Chi-Fung Chan G, Li H, Sun H
iScience 2020 May 22;23(5):101054
iScience 2020 May 22;23(5):101054
Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice.
Yu M, Ren L, Liang F, Zhang Y, Jiang L, Ma W, Li C, Li X, Ye X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 May 17;76:153216
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 May 17;76:153216
α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish.
Shang X, Ji X, Dang J, Wang L, Sun C, Liu K, Sik A, Jin M
Toxicology letters 2020 May 15;324:1-11
Toxicology letters 2020 May 15;324:1-11
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, Tan P, Xia X, Du Y, Fu W
Life sciences 2020 May 15;249:117517
Life sciences 2020 May 15;249:117517
CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma.
Li T, Wu S, Jia L, Cao W, Yao Y, Zhao G, Li H
Cancer biology & medicine 2020 May 15;17(2):357-370
Cancer biology & medicine 2020 May 15;17(2):357-370
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
SMAD4 activates Wnt signaling pathway to inhibit granulosa cell apoptosis.
Du X, Li Q, Yang L, Liu L, Cao Q, Li Q
Cell death & disease 2020 May 15;11(5):373
Cell death & disease 2020 May 15;11(5):373
Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke.
Zhang KY, Rui G, Zhang JP, Guo L, An GZ, Lin JJ, He W, Ding GR
BMC neuroscience 2020 May 12;21(1):21
BMC neuroscience 2020 May 12;21(1):21
Gasdermine E-Dependent Mitochondrial Pyroptotic Pathway in Dermatomyositis: A Possible Mechanism of Perifascicular Atrophy.
Liu M, Li L, Dai T, Hou Y, Li W, Zhao Y, Fang Q, Yan C
Journal of neuropathology and experimental neurology 2020 May 1;79(5):551-561
Journal of neuropathology and experimental neurology 2020 May 1;79(5):551-561
Comprehensive identification of signaling pathways for idiopathic pulmonary arterial hypertension.
Liu B, Zhu L, Yuan P, Marsboom G, Hong Z, Liu J, Zhang P, Hu Q
American journal of physiology. Cell physiology 2020 May 1;318(5):C913-C930
American journal of physiology. Cell physiology 2020 May 1;318(5):C913-C930
Camellia oil (Camellia oleifera Abel.) attenuates CCl(4)-induced liver fibrosis via suppressing hepatocyte apoptosis in mice.
Lei X, Liu Q, Liu Q, Cao Z, Zhang J, Kuang T, Fang Y, Liu G, Qian K, Fu J, Du H, Liu Z, Xiao Z, Li C, Xu X
Food & function 2020 May 1;11(5):4582-4590
Food & function 2020 May 1;11(5):4582-4590
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
Jiang L, He C, Zhang X, Chen Y, Li G
Translational cancer research 2020 Mar;9(3):1851-1860
Translational cancer research 2020 Mar;9(3):1851-1860
LncRNA FAM66C inhibits pancreatic cancer progression by sponging miR-574-3p.
Zhu J, Zhu S, Yu Q, Wu Y
Translational cancer research 2020 Mar;9(3):1806-1817
Translational cancer research 2020 Mar;9(3):1806-1817
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, Niu L, Liu H, Bao D
Journal of natural medicines 2020 Mar;74(2):399-408
Journal of natural medicines 2020 Mar;74(2):399-408
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway.
Wang Z, Li Y, Fan L, Zhao Q, Tan B, Liu R, Li F
Neoplasma 2020 Mar;67(2):277-285
Neoplasma 2020 Mar;67(2):277-285
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
Qi W, Li Z, Yang C, Jiangshan Dai J, Zhang Q, Wang D, Wu C, Xia L, Xu S
Oncology reports 2020 Mar;43(3):839-850
Oncology reports 2020 Mar;43(3):839-850
FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
Li C, Zhou J, Liu Z, Zhou J, Yao W, Tao J, Shen M, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3631-3645
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3631-3645
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
Gucer H, Caliskan S, Kefeli M, Mete O
Endocrine pathology 2020 Mar;31(1):33-38
Endocrine pathology 2020 Mar;31(1):33-38
miR-7112-3p targets PERK to regulate the endoplasmic reticulum stress pathway and apoptosis induced by photodynamic therapy in colorectal cancer CX-1 cells.
Kong F, Zou H, Liu X, He J, Zheng Y, Xiong L, Miao X
Photodiagnosis and photodynamic therapy 2020 Mar;29:101663
Photodiagnosis and photodynamic therapy 2020 Mar;29:101663
Acrolein-induced apoptosis of smooth muscle cells through NEAT1-Bmal1/Clock pathway and a protection from asparagus extract.
Chen L, Wu X, Zeb F, Huang Y, An J, Jiang P, Chen A, Xu C, Feng Q
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113735
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113735
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis.
Gong Q, Song C, Wang X, Wang R, Cai G, Liang X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):542-551
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):542-551
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, Xu Z, Wang X, Wang Y, Zhu Y, Wang W
Archives of oral biology 2020 Mar;111:104646
Archives of oral biology 2020 Mar;111:104646
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
Zhang K, Bai Y, Xu R, Li J, Guan F
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Zhang X, Wang Z, Li W, Huang R, Zheng D, Bi G
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Wu K, Li L, Li L, Wang D
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway.
Ma L, Sun Y, Li D, Li H, Jin X, Ren D
Aging 2020 Mar 22;12(6):5336-5351
Aging 2020 Mar 22;12(6):5336-5351
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, Yu M, Zhang Y, Li X, Ye X
Life sciences 2020 Mar 15;245:117387
Life sciences 2020 Mar 15;245:117387
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Yu M, Zeng M, Pan Z, Wu F, Guo L, He G
European journal of medicinal chemistry 2020 Mar 1;189:112076
European journal of medicinal chemistry 2020 Mar 1;189:112076
Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage.
Lin QS, Wang WX, Lin YX, Lin ZY, Yu LH, Kang Y, Kang DZ
Journal of neurosurgery 2020 Mar 1;132(3):777-787
Journal of neurosurgery 2020 Mar 1;132(3):777-787
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Zhu X, Feng J, Fu W, Shu X, Wan X, Liu J
International journal of molecular medicine 2020 Jun;45(6):1838-1850
International journal of molecular medicine 2020 Jun;45(6):1838-1850
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Peng F, Li G, Xie Y, Yin HY, Li XJ, Yang YD
Journal of food biochemistry 2020 Jun;44(6):e13222
Journal of food biochemistry 2020 Jun;44(6):e13222
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
Liu X, Hu R, Pei L, Si P, Wang C, Tian X, Wang X, Liu H, Wang B, Xia Z, Xu Y, Song B
Experimental neurology 2020 Jun;328:113233
Experimental neurology 2020 Jun;328:113233
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Wu J, He J, Tian X, Luo Y, Zhong J, Zhang H, Li H, Cen B, Jiang T, Sun X
Journal of neurochemistry 2020 Jun;153(6):710-726
Journal of neurochemistry 2020 Jun;153(6):710-726
Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α.
Huang Y, Tan F, Zhuo Y, Liu J, He J, Duan D, Lu M, Hu Z
Aging 2020 Jun 7;12(11):10931-10950
Aging 2020 Jun 7;12(11):10931-10950
Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway.
Fang H, Yang K, Tang P, Zhao N, Ma R, Luo X, Liu Q
Aging 2020 Jun 30;12(13):12850-12868
Aging 2020 Jun 30;12(13):12850-12868
Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model.
Shi Z, Wang Q, Zhang Y, Jiang D
Stem cell research & therapy 2020 Jun 26;11(1):253
Stem cell research & therapy 2020 Jun 26;11(1):253
Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis.
Gong Y, Zhang YL, Wang Z, Song HH, Liu YC, Lv AW, Tian LL, Zhu WL, Fu Y, Ding XL, Cui LJ, Yan YP
Journal of neuroinflammation 2020 Jun 25;17(1):198
Journal of neuroinflammation 2020 Jun 25;17(1):198
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Wang Y, Li C, Li J, Wang G, Li L
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis.
Dong X, Kong F, Liu C, Dai S, Zhang Y, Xiao F, Zhang H, Wu CT, Wang H
Stem cell research & therapy 2020 Jun 10;11(1):229
Stem cell research & therapy 2020 Jun 10;11(1):229
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, Ye X
Planta medica 2020 Jul;86(11):767-775
Planta medica 2020 Jul;86(11):767-775
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, Chu L
International immunopharmacology 2020 Jul;84:106548
International immunopharmacology 2020 Jul;84:106548
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, Li S, Zhang J, Dai W, Xu X, Mao Y, Xu S, Chen K, Li J, Guo C
International immunopharmacology 2020 Jul;84:106529
International immunopharmacology 2020 Jul;84:106529
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
Tao L, Liu X, Da W, Tao Z, Zhu Y
Neurological research 2020 Jul;42(7):597-604
Neurological research 2020 Jul;42(7):597-604
The roles of SHANK1 in the development of colon cancer.
Wang L, Lv Y, Liu G
Cell biochemistry and function 2020 Jul;38(5):669-675
Cell biochemistry and function 2020 Jul;38(5):669-675
2-Deoxy-D-glucose enhances the anti-cancer effects of idarubicin on idarubicin-resistant P388 leukemia cells.
Matsuo T, Konya Y, Hirayama E, Sadzuka Y
Oncology letters 2020 Jul;20(1):962-966
Oncology letters 2020 Jul;20(1):962-966
ZX-29, a novel ALK inhibitor, induces apoptosis via ER stress in ALK rearrangement NSCLC cells and overcomes cell resistance caused by an ALK mutation.
Gou W, Li Z, Xu X, Shen J, Guo M, Zhou X, Zhang X, Wu Y, Zhai X, Zuo D
Biochimica et biophysica acta. Molecular cell research 2020 Jul;1867(7):118712
Biochimica et biophysica acta. Molecular cell research 2020 Jul;1867(7):118712
Mkrn2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis.
Qian YC, Xie YX, Wang CS, Shi ZM, Jiang CF, Tang YY, Qian X, Wang L, Jiang BH
Asian journal of andrology 2020 Jul-Aug;22(4):414-421
Asian journal of andrology 2020 Jul-Aug;22(4):414-421
Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells.
Li C, Meng X, Liu S, Li W, Zhang X, Zhou J, Yao W, Dong C, Liu Z, Zhou J, Li J, Tao J, Wu W, Shen M, Liu H
Development (Cambridge, England) 2020 Jul 3;147(13)
Development (Cambridge, England) 2020 Jul 3;147(13)
Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation.
Wang K, Tu Y, Wan JB, Chen M, He C
Carcinogenesis 2020 Jul 10;41(6):804-816
Carcinogenesis 2020 Jul 10;41(6):804-816
An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury.
He S, Li A, Zhang W, Zhang L, Liu Y, Li K, Qin X
Chemico-biological interactions 2020 Jul 1;325:109096
Chemico-biological interactions 2020 Jul 1;325:109096
Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury.
Pang H, Wang N, Chai J, Wang X, Zhang Y, Bi Z, Wu W, He G
European journal of medicinal chemistry 2020 Jul 1;197:112314
European journal of medicinal chemistry 2020 Jul 1;197:112314
Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Li S, Li XY, Zhang TJ, Kamara MO, Liang JW, Zhu J, Meng FH
Bioorganic chemistry 2020 Jan;94:103385
Bioorganic chemistry 2020 Jan;94:103385
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, He G, Han B
Cell proliferation 2020 Jan;53(1):e12701
Cell proliferation 2020 Jan;53(1):e12701
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, Sun S, Chu X, Cheng J, Guan S, Li Z, Chu L
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Zhang L, Yan X, Yu S, Zhong X, Tian R, Xu L, Bian X, Su J
Oncology letters 2020 Jan;19(1):753-762
Oncology letters 2020 Jan;19(1):753-762
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Zheng Y, Nie P, Xu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition.
Chen Z, Zhang J, Xue H, Qian M, Guo X, Gao X, Xu J, Qi Y, Sun X, Li G
Integrative cancer therapies 2020 Jan-Dec;19:1534735419900927
Integrative cancer therapies 2020 Jan-Dec;19:1534735419900927
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
Zhu Y, Shi F, Wang M, Ding J
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
He X, Chen S, Li C, Ban J, Wei Y, He Y, Liu F, Chen Y, Chen J
Cells 2020 Jan 4;9(1)
Cells 2020 Jan 4;9(1)
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, Yu Q, Kong R, Li S, Zhang J, Ji J, Wu J, Mo W, Xu X, Guo C
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Disruption of Midkine gene reduces traumatic brain injury through the modulation of neuroinflammation.
Takada S, Sakakima H, Matsuyama T, Otsuka S, Nakanishi K, Norimatsu K, Itashiki Y, Tani A, Kikuchi K
Journal of neuroinflammation 2020 Jan 29;17(1):40
Journal of neuroinflammation 2020 Jan 29;17(1):40
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Wang J, Xu H, Cheng X, Yang J, Yan Z, Ma H, Zhao Y, Ommati MM, Manthari RK, Wang J
Food & function 2020 Jan 29;11(1):1155-1164
Food & function 2020 Jan 29;11(1):1155-1164
Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression.
Li C, Xia M, Wang H, Li W, Peng J, Jiang H
Life sciences 2020 Jan 15;241:117143
Life sciences 2020 Jan 15;241:117143
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Zhang W, Zhu T, Chen L, Luo W, Chao J
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, Song Y, Wang K, Zhao K, Yang S, Yang C
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
Zhu CL, Huang Q
Digestive diseases and sciences 2020 Feb;65(2):489-499
Digestive diseases and sciences 2020 Feb;65(2):489-499
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Liang LY, Wang MM, Liu M, Zhao W, Wang X, Shi L, Zhu MJ, Zhao YL, Liu L, Maurya P, Wang Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
Chen M, Zhu LL, Su JL, Li GL, Wang J, Zhang YN
Human & experimental toxicology 2020 Feb;39(2):173-181
Human & experimental toxicology 2020 Feb;39(2):173-181
MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis.
Li S, Xie Y, Yang B, Huang S, Zhang Y, Jia Z, Ding G, Zhang A
Apoptosis : an international journal on programmed cell death 2020 Feb;25(1-2):92-104
Apoptosis : an international journal on programmed cell death 2020 Feb;25(1-2):92-104
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, Yue Z
Molecular medicine reports 2020 Feb;21(2):597-606
Molecular medicine reports 2020 Feb;21(2):597-606
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
Effect of S-Allyl -L-Cysteine on MCF-7 Cell Line 3-Mercaptopyruvate Sulfurtransferase/Sulfane Sulfur System, Viability and Apoptosis.
Bronowicka-Adamska P, Bentke A, Lasota M, Wróbel M
International journal of molecular sciences 2020 Feb 6;21(3)
International journal of molecular sciences 2020 Feb 6;21(3)
The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice.
Liu Q, Zhang S, Zhu D, Tang X, Che Y, Feng X
Behavioural brain research 2020 Feb 3;379:112337
Behavioural brain research 2020 Feb 3;379:112337
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Xiong Y, Yin Q, Li J, He S
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
PUMA-mediated epithelial cell apoptosis promotes Helicobacter pylori infection-mediated gastritis.
Dang Y, Zhang Y, Xu L, Zhou X, Gu Y, Yu J, Jin S, Ji H, Shu Y, Zhang G, Cui S, Sun J
Cell death & disease 2020 Feb 20;11(2):139
Cell death & disease 2020 Feb 20;11(2):139
Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.
Fan J, Ren D, Wang J, Liu X, Zhang H, Wu M, Yang G
Cell death & disease 2020 Feb 18;11(2):126
Cell death & disease 2020 Feb 18;11(2):126
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Shopit A, Niu M, Wang H, Tang Z, Li X, Tesfaldet T, Ai J, Ahmad N, Al-Azab M, Tang Z
Life sciences 2020 Feb 1;242:117248
Life sciences 2020 Feb 1;242:117248
Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways.
Zeng Q, Zeng Y, Nie X, Guo Y, Zhan Y
Planta medica 2020 Dec;86(18):1401-1410
Planta medica 2020 Dec;86(18):1401-1410
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
E L, Jiang H
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
Dong M, Xiao Q, Hu J, Cheng F, Zhang P, Zong W, Tang Q, Li X, Mao F, He Y, Yu X, Wan F, Lei T, Guo D, Wang B
Cancer gene therapy 2020 Dec;27(12):878-897
Cancer gene therapy 2020 Dec;27(12):878-897
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Hou HW, Xue P, Wang Y, Li YK
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Chen X, Ji S, Si J, Zhang X, Wang X, Guo Y, Zou X
Molecular medicine reports 2020 Dec;22(6):5243-5250
Molecular medicine reports 2020 Dec;22(6):5243-5250
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Xue Y, Li M, Xue Y, Jin W, Han X, Zhang J, Chu X, Li Z, Chu L
Molecular medicine reports 2020 Dec;22(6):4663-4674
Molecular medicine reports 2020 Dec;22(6):4663-4674
FAIM-S functions as a negative regulator of NF-κB pathway and blocks cell cycle progression in NSCLC cells.
Wang P, Xun W, Han T, Cheng Z
Cell cycle (Georgetown, Tex.) 2020 Dec;19(24):3458-3467
Cell cycle (Georgetown, Tex.) 2020 Dec;19(24):3458-3467
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Wang Y, Chen Y, Zhang H, Chen J, Cao J, Chen Q, Li X, Sun C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811
Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents.
Xu C, Zhou W, Dong G, Qiao H, Peng J, Jia P, Li Y, Liu H, Sun K, Zhao W
Bioorganic chemistry 2020 Dec;105:104424
Bioorganic chemistry 2020 Dec;105:104424
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
SMARCA2 is regulated by NORFA-miR-29c, a novel pathway that controls granulosa cell apoptosis and is related to female fertility.
Du X, Liu L, Wu W, Li P, Pan Z, Zhang L, Liu J, Li Q
Journal of cell science 2020 Dec 7;133(23)
Journal of cell science 2020 Dec 7;133(23)
Cryogen spray cooling mitigates inflammation and injury-induced CISD2 decline in rat spinal cord hemisection model.
Kung WM, Chang CJ, Chen TY, Lin MS
Journal of integrative neuroscience 2020 Dec 30;19(4):619-628
Journal of integrative neuroscience 2020 Dec 30;19(4):619-628
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wang C, Nie G, Zhuang Y, Hu R, Wu H, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.
Guan S, Tao S, Huang Y, Jin Y, Hu Y, Lu J
Ecotoxicology and environmental safety 2020 Dec 1;205:111062
Ecotoxicology and environmental safety 2020 Dec 1;205:111062
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Zhang L, Wang Z, Kong D, Zhao X, Chen X, Chai W
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Yang T, Fan TJ, Xu B
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104868
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104868
Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis.
Su Q, Wang J, Liu F, Zhang Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104840
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104840
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C
Cell proliferation 2020 Aug;53(8):e12869
Cell proliferation 2020 Aug;53(8):e12869
LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR-200c-3p to upregulate ANLN.
Zhang M, Wang F, Xiang Z, Huang T, Zhou WB
Clinical and experimental pharmacology & physiology 2020 Aug;47(8):1464-1472
Clinical and experimental pharmacology & physiology 2020 Aug;47(8):1464-1472
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner.
Huang L, Yan W, Cai B, Song Y, Lv Q, Wang G, Wang L, Wang Z
Biomaterials 2020 Aug;250:120021
Biomaterials 2020 Aug;250:120021
Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration.
Guo Y, Zhu H, Weng M, Chen B, Wang C, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110366
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
A mitochondria-targeted anticancer nanoplatform with deep penetration for enhanced synergistic sonodynamic and starvation therapy.
Zhang R, Zhang L, Ran H, Li P, Huang J, Tan M, Yang Y, Wang Z
Biomaterials science 2020 Aug 21;8(16):4581-4594
Biomaterials science 2020 Aug 21;8(16):4581-4594
Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARγ(1).
Cui L, Xu F, Wu K, Li L, Qiao T, Li Z, Chen T, Sun C
European journal of pharmacology 2020 Aug 15;881:173230
European journal of pharmacology 2020 Aug 15;881:173230
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, Sun L
Life sciences 2020 Aug 15;255:117846
Life sciences 2020 Aug 15;255:117846
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, Cheng C, Wang G, Sun X
Neuroscience 2020 Aug 1;440:160-174
Neuroscience 2020 Aug 1;440:160-174
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Cao Y, Liu C, Wang Q, Wang W, Tao E, Wan L
Experimental cell research 2020 Aug 1;393(1):112058
Experimental cell research 2020 Aug 1;393(1):112058
Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
Liu Q, Tan Y, Qu T, Zhang J, Duan X, Xu H, Mu Y, Ma H, Wang F
Life sciences 2020 Aug 1;254:117772
Life sciences 2020 Aug 1;254:117772
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Luo J, Yang C, Luo X, Yang Y, Li J, Song B, Zhao J, Li L
Life sciences 2020 Aug 1;254:117590
Life sciences 2020 Aug 1;254:117590
Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway.
Liu Y, Wang H, Liu N, Du J, Lan X, Qi X, Zhuang C, Sun T, Li Y, Yu J
Life sciences 2020 Aug 1;254:116444
Life sciences 2020 Aug 1;254:116444
Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels.
Liu W, Xiao K, Ren L, Sui Y, Chen J, Zhang T, Li XQ, Cao W
Carbohydrate polymers 2020 Aug 1;241:116279
Carbohydrate polymers 2020 Aug 1;241:116279
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation.
Feng Y, Wu JJ, Sun ZL, Liu SY, Zou ML, Yuan ZD, Yu S, Lv GZ, Yuan FL
EBioMedicine 2020 Apr;54:102715
EBioMedicine 2020 Apr;54:102715
Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2.
Bi W, Xiao JC, Liu RJ, Zhou LY, Zhang S, Yang M, Zhang PF
Investigational new drugs 2020 Apr;38(2):287-298
Investigational new drugs 2020 Apr;38(2):287-298
Inhibition of microRNA-327 ameliorates ischemia/reperfusion injury-induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain.
Li Q, Yang J, Zhang J, Liu XW, Yang CJ, Fan ZX, Wang HB, Yang Y, Zheng T, Yang J
Journal of cellular physiology 2020 Apr;235(4):3753-3767
Journal of cellular physiology 2020 Apr;235(4):3753-3767
The Effects of Daxx Knockout on Pluripotency and Differentiation of Mouse Induced Pluripotent Stem Cells.
Liu H, Liu Z, Gao M, Hu X, Sun R, Shen X, Liu F, Shen J, Shan Z, Lei L
Cellular reprogramming 2020 Apr;22(2):90-98
Cellular reprogramming 2020 Apr;22(2):90-98
METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway.
Liang S, Guan H, Lin X, Li N, Geng F, Li J
Oncology letters 2020 Apr;19(4):3197-3204
Oncology letters 2020 Apr;19(4):3197-3204
The inhibitory effect and safety of GANT61 on HeLa cells in nude mice.
Chang Y, Chen H, Duan J, Wu W, Le F, Mou F
Experimental and molecular pathology 2020 Apr;113:104352
Experimental and molecular pathology 2020 Apr;113:104352
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Zhang Y, Zhang X, Wei Q, Leng S, Li C, Han B, Bai Y, Zhang H, Yao H
Translational stroke research 2020 Apr;11(2):267-287
Translational stroke research 2020 Apr;11(2):267-287
Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis.
Shi B, Huang Y, Ni J, Chen J, Wei J, Gao H, Li L, Zhou Z, Wang Y, Xu Y, Xu Z, Mao J, Fan G
Scientific reports 2020 Apr 8;10(1):6105
Scientific reports 2020 Apr 8;10(1):6105
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Li X, Yao Z, Yang D, Jiang X, Sun J, Tian L, Hu J, Wu B, Bai W
Journal of hazardous materials 2020 Apr 5;387:121706
Journal of hazardous materials 2020 Apr 5;387:121706
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Chen HX, Liang FC, Gu P, Xu BL, Xu HJ, Wang WT, Hou JY, Xie DX, Chai XQ, An SJ
Cell death & disease 2020 Apr 27;11(4):288
Cell death & disease 2020 Apr 27;11(4):288
PTEN-induced kinase 1-induced dynamin-related protein 1 Ser637 phosphorylation reduces mitochondrial fission and protects against intestinal ischemia reperfusion injury.
Qasim W, Li Y, Sun RM, Feng DC, Wang ZY, Liu DS, Yao JH, Tian XF
World journal of gastroenterology 2020 Apr 21;26(15):1758-1774
World journal of gastroenterology 2020 Apr 21;26(15):1758-1774
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene.
Huang G, Ma J, Zhang L
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 19;26:e920623
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 19;26:e920623
Resveratrol Attenuates Aflatoxin B(1)-Induced ROS Formation and Increase of m(6)A RNA Methylation.
Wu J, Gan Z, Zhuo R, Zhang L, Wang T, Zhong X
Animals : an open access journal from MDPI 2020 Apr 13;10(4)
Animals : an open access journal from MDPI 2020 Apr 13;10(4)
VX-765 attenuates atherosclerosis in ApoE deficient mice by modulating VSMCs pyroptosis.
Li Y, Niu X, Xu H, Li Q, Meng L, He M, Zhang J, Zhang Z, Zhang Z
Experimental cell research 2020 Apr 1;389(1):111847
Experimental cell research 2020 Apr 1;389(1):111847
The FSH-HIF-1α-VEGF Pathway Is Critical for Ovulation and Oocyte Health but Not Necessary for Follicular Growth in Mice.
Li C, Liu Z, Li W, Zhang L, Zhou J, Sun M, Zhou J, Yao W, Zhang X, Wang H, Tao J, Shen M, Liu H
Endocrinology 2020 Apr 1;161(4)
Endocrinology 2020 Apr 1;161(4)
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, Zhou R, Cai L, Chen L, Tao G
American journal of cancer research 2019;9(5):887-905
American journal of cancer research 2019;9(5):887-905
Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation.
Zhu J, Liu B, Wang Z, Wang D, Ni H, Zhang L, Wang Y
Theranostics 2019;9(23):6901-6919
Theranostics 2019;9(23):6901-6919
Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.
Zhu Y, Yu F, Tan Y, Hong Y, Meng T, Liu Y, Dai S, Qiu G, Yuan H, Hu F
Theranostics 2019;9(23):6764-6779
Theranostics 2019;9(23):6764-6779
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.
Zou W, Niu C, Fu Z, Gong C
Cell & bioscience 2019;9:18
Cell & bioscience 2019;9:18
Saikosaponin A Inhibits Triple-Negative Breast Cancer Growth and Metastasis Through Downregulation of CXCR4.
Wang Y, Zhao L, Han X, Wang Y, Mi J, Wang C, Sun D, Fu Y, Zhao X, Guo H, Wang Q
Frontiers in oncology 2019;9:1487
Frontiers in oncology 2019;9:1487
SIX1 Activates STAT3 Signaling to Promote the Proliferation of Thyroid Carcinoma via EYA1.
Kong D, Li A, Liu Y, Cui Q, Wang K, Zhang D, Tang J, Du Y, Liu Z, Wu G, Wu K
Frontiers in oncology 2019;9:1450
Frontiers in oncology 2019;9:1450
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Wang J, Shao L, Wang CZ, Zhou HH, Yuan CS, Huang WH
Nutrition and cancer 2019;71(3):472-482
Nutrition and cancer 2019;71(3):472-482
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
Wang J, Shao L, Rao T, Zhang W, Huang WH
The American journal of Chinese medicine 2019;47(6):1381-1404
The American journal of Chinese medicine 2019;47(6):1381-1404
Gefitinib-coated balloon inhibits the excessive hyperplasia of intima after vascular injuries through PI3K/AKT pathway.
Tang F, Liu M, Zeng O, Tan W, Long J, Liu S, Yang J, Chu C
Technology and health care : official journal of the European Society for Engineering and Medicine 2019;27(S1):331-343
Technology and health care : official journal of the European Society for Engineering and Medicine 2019;27(S1):331-343
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, Kang Z
Cellular & molecular biology letters 2019;24:19
Cellular & molecular biology letters 2019;24:19
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z
Oxidative medicine and cellular longevity 2019;2019:6521218
Oxidative medicine and cellular longevity 2019;2019:6521218
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, Zheng T, Pu S, Xia X, Fu W
Oxidative medicine and cellular longevity 2019;2019:3765898
Oxidative medicine and cellular longevity 2019;2019:3765898
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, Li S, Feng J, Liu T, Zhang J, Chen J, Zhou Y, Mao Y, Wang F, Dai W, Fan X, Guo C, Wu J
Mediators of inflammation 2019;2019:3240713
Mediators of inflammation 2019;2019:3240713
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Yan X, Fu X, Jia Y, Ma X, Tao J, Yang T, Ma H, Liang X, Liu X, Yang J, Wei J
Oxidative medicine and cellular longevity 2019;2019:2654910
Oxidative medicine and cellular longevity 2019;2019:2654910
Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms.
Wang Y, Wu JZ, Li Y, Qi X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2089586
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2089586
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.
Yang Y, Pang B, Liu Z, Li J, Zhang Z, Zhang R, Hou X, Guo H, Chi L, Pang Q, Xin T
Oxidative medicine and cellular longevity 2019;2019:1292891
Oxidative medicine and cellular longevity 2019;2019:1292891
Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway.
Wu D, Liu Z, Li J, Zhang Q, Zhong P, Teng T, Chen M, Xie Z, Ji A, Li Y
Cancer cell international 2019;19:43
Cancer cell international 2019;19:43
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell.
Li Y, Wang C, Lu J, Huang K, Han Y, Chen J, Yang Y, Liu B
International journal of medical sciences 2019;16(12):1593-1603
International journal of medical sciences 2019;16(12):1593-1603
RRM2 is a potential prognostic biomarker with functional significance in glioma.
Sun H, Yang B, Zhang H, Song J, Zhang Y, Xing J, Yang Z, Wei C, Xu T, Yu Z, Xu Z, Hou M, Ji M, Zhang Y
International journal of biological sciences 2019;15(3):533-543
International journal of biological sciences 2019;15(3):533-543
Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway.
Wu H, Ding J, Li S, Lin J, Jiang R, Lin C, Dai L, Xie C, Lin D, Xu H, Gao W, Zhou K
International journal of biological sciences 2019;15(2):325-340
International journal of biological sciences 2019;15(2):325-340
Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression.
Zhang P, He D, Song E, Jiang M, Song Y
PloS one 2019;14(10):e0223760
PloS one 2019;14(10):e0223760
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
Sun Y, Gong J, Cao Y
International journal of nanomedicine 2019;14:9285-9294
International journal of nanomedicine 2019;14:9285-9294
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771
International journal of nanomedicine 2019;14:3753-3771
Treatment With 2-BFI Attenuated Spinal Cord Injury by Inhibiting Oxidative Stress and Neuronal Apoptosis via the Nrf2 Signaling Pathway.
Lin X, Zhu J, Ni H, Rui Q, Sha W, Yang H, Li D, Chen G
Frontiers in cellular neuroscience 2019;13:567
Frontiers in cellular neuroscience 2019;13:567
Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway.
Zhu HF, Shao Y, Qin L, Wang JH, Feng S, Jiang YB, Wan D
Drug design, development and therapy 2019;13:4145-4157
Drug design, development and therapy 2019;13:4145-4157
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.
Guo Z, Tian Y, Guo Y, Li B, Liu X, Xie K, Song Y, Wang D
Frontiers in cellular neuroscience 2019;13:392
Frontiers in cellular neuroscience 2019;13:392
Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress.
Lin J, Jia C, Wang Y, Jiang S, Jia Z, Chen N, Sheng S, Li S, Jiang L, Xu H, Zhou K, Chen Y
Drug design, development and therapy 2019;13:1461-1472
Drug design, development and therapy 2019;13:1461-1472
NCAPG Promotes The Proliferation Of Hepatocellular Carcinoma Through PI3K/AKT Signaling.
Gong C, Ai J, Fan Y, Gao J, Liu W, Feng Q, Liao W, Wu L
OncoTargets and therapy 2019;12:8537-8552
OncoTargets and therapy 2019;12:8537-8552
GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
Wang Y, Cao P, Alshwmi M, Jiang N, Xiao Z, Jiang F, Gu J, Wang X, Sun X, Li S
OncoTargets and therapy 2019;12:6639-6651
OncoTargets and therapy 2019;12:6639-6651
Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis.
Xu W, Hu GQ, Da Costa C, Tang JH, Li QR, Du L, Pan YW, Lv SQ
OncoTargets and therapy 2019;12:3467-3480
OncoTargets and therapy 2019;12:3467-3480
Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells.
Shi S, Zheng G, Yang C, Chen X, Yan Q, Jiang F, Jiang X, Xin Y, Jiang G
OncoTargets and therapy 2019;12:11715-11727
OncoTargets and therapy 2019;12:11715-11727
P-AKT2/SPK1 (P-SPK1) and P-MEK/P-ERK cell signaling pathways are involved in LPS-induced macrophage migration.
Lei Y, Yang Y, Zhao J, Gao H, Chen R, Bai B, Kang X, He Y, Ding L, Wei T, Fu X, Zhao L, Li X
American journal of translational research 2019;11(5):2725-2741
American journal of translational research 2019;11(5):2725-2741
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Cao X, He Y, Li X, Xu Y, Liu X
American journal of translational research 2019;11(2):641-654
American journal of translational research 2019;11(2):641-654
Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies.
Jiang J, Wang X, Gao G, Liu X, Chang H, Xiong R, Lu J, Sun Z
American journal of translational research 2019;11(10):6382-6392
American journal of translational research 2019;11(10):6382-6392
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, Li S, Wang Y, Lin D, Gao W, Kong J, Xu H, Zhou K
American journal of translational research 2019;11(1):379-392
American journal of translational research 2019;11(1):379-392
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W
Cancer management and research 2019;11:5799-5811
Cancer management and research 2019;11:5799-5811
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Li T, Li L, Wu X, Tian K, Wang Y
Cancer management and research 2019;11:2179-2188
Cancer management and research 2019;11:2179-2188
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Li M, Chen C, Zhang W, Gao R, Wang Q, Chen H, Zhang S, Mao X, Leblanc M, Behensky A, Zhang Z, Gan L, Yu H, Zhu T, Liu J
Frontiers in aging neuroscience 2019;11:181
Frontiers in aging neuroscience 2019;11:181
Simultaneous Inhibition of EGFR and HER2 via Afatinib Augments the Radiosensitivity of Nasopharyngeal Carcinoma Cells.
Huang F, Liang X, Min X, Zhang Y, Wang G, Peng Z, Peng F, Li M, Chen L, Chen Y
Journal of Cancer 2019;10(9):2063-2073
Journal of Cancer 2019;10(9):2063-2073
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Wu D, Li M, Gao Y, Tian W, Li J, Zhang Q, Liu Z, Zheng M, Wang H, Wang J, Teng T, Zhang L, Ji X, Xie Z, Ji A, Li Y
Journal of Cancer 2019;10(7):1693-1706
Journal of Cancer 2019;10(7):1693-1706
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
Peng Y, Wang L, Wu L, Zhang L, Nie G, Guo M
Journal of Cancer 2019;10(24):6124-6134
Journal of Cancer 2019;10(24):6124-6134
Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
Tian N, Shangguan W, Zhou Z, Yao Y, Fan C, Cai L
Journal of Cancer 2019;10(24):6074-6087
Journal of Cancer 2019;10(24):6074-6087
The Radiosensitization of Sodium Glycididazole on Nasopharyngeal Carcinoma Cells via Enhancing DNA Damage and Promoting Apoptosis.
Min X, Huang F, Huang H, Zhao S, Wang G, Zhou M, Chen Z, Li M, Chen Y
Journal of Cancer 2019;10(2):305-312
Journal of Cancer 2019;10(2):305-312
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Zhang R, Wang C, Tian Y, Yao Y, Mao J, Wang H, Li Z, Xu Y, Ye M, Wang L
Journal of Cancer 2019;10(16):3871-3882
Journal of Cancer 2019;10(16):3871-3882
Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer.
Liao X, Fan Y, Hou J, Chen X, Xu X, Yang Y, Shen J, Mi P, Huang X, Zhang W, Cao H, Hong X, Hu T, Zhan YY
Journal of Cancer 2019;10(16):3678-3690
Journal of Cancer 2019;10(16):3678-3690
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, Cai D, Rui J, Zhang L
Frontiers in pharmacology 2019;10:676
Frontiers in pharmacology 2019;10:676
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Suo L, Chang X, Xu N, Ji H
Frontiers in endocrinology 2019;10:370
Frontiers in endocrinology 2019;10:370
Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice.
Zhang Y, Xie H, Tang W, Zeng X, Lin Y, Xu L, Xiao L, Xu J, Wu Z, Yuan D
Frontiers in microbiology 2019;10:2280
Frontiers in microbiology 2019;10:2280
Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression.
Li H, Chen W, Chen Y, Zhou Q, Xiao P, Tang R, Xue J
Frontiers in pharmacology 2019;10:1197
Frontiers in pharmacology 2019;10:1197
Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration.
Nie X, Xia F, Liu Y, Zhou Y, Ye W, Hean P, Meng J, Liu H, Liu L, Wen J, Ren X, Chen WD, Wang YD
Frontiers in pharmacology 2019;10:1110
Frontiers in pharmacology 2019;10:1110
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
Li J, Bao G, ALyafeai E, Ding J, Li S, Sheng S, Shen Z, Jia Z, Lin C, Zhang C, Lou Z, Xu H, Gao W, Zhou K
Frontiers in pharmacology 2019;10:1017
Frontiers in pharmacology 2019;10:1017
Prazosin inhibits the growth and mobility of osteosarcoma cells.
An M, Ma WH, Jia HW, Li YW, Feng JJ, Meng J, Qi H, Liu J
Translational cancer research 2019 Sep;8(5):1997-2004
Translational cancer research 2019 Sep;8(5):1997-2004
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
Chen L, Tian Q, Wang W
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Xu S, Ma H, Bo Y, Shao M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, Hu Y, Wu G, Dong X
Aging 2019 Sep 8;11(17):6734-6761
Aging 2019 Sep 8;11(17):6734-6761
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Xu X, Chen X, Xu M, Liu X, Pan B, Qin J, Xu T, Zeng K, Pan Y, He B, Sun H, Sun L, Wang S
Aging 2019 Sep 22;11(18):7357-7385
Aging 2019 Sep 22;11(18):7357-7385
Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells.
Li M, Hao S, Li C, Xiao H, Sun L, Yu Z, Zhang N, Xiong Y, Zhao D, Yin Y
Biomolecules 2019 Sep 19;9(9)
Biomolecules 2019 Sep 19;9(9)
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Jing L, Jiang JR, Liu DM, Sheng JW, Zhang WF, Li ZJ, Wei LY
Molecules (Basel, Switzerland) 2019 Sep 16;24(18)
Molecules (Basel, Switzerland) 2019 Sep 16;24(18)
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Lin J, Fang L, Li H, Li Z, Lyu L, Wang H, Xiao J
European journal of pharmacology 2019 Sep 15;859:172490
European journal of pharmacology 2019 Sep 15;859:172490
Cypermethrin exposure reduces the ovarian reserve by causing mitochondrial dysfunction in granulosa cells.
Wang H, He Y, Cheng D, Pu D, Tan R, Gao L, Cui Y, Wu J
Toxicology and applied pharmacology 2019 Sep 15;379:114693
Toxicology and applied pharmacology 2019 Sep 15;379:114693
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, Zhao J, Xia S, Fan S, Yu X, Du Y, Hou L, Li Z, Ding Z, An S, Huang B, Li L, Tang J, Ju J, Guan H, Song B
Cancer letters 2019 Sep 10;459:122-134
Cancer letters 2019 Sep 10;459:122-134
DNA methylation and RASSF4 expression are involved in T-2 toxin-induced hepatotoxicity.
Liu A, Xu X, Hou R, Badawy S, Tao Y, Chen D, Ihsan A, Wang X, Wu Q, Yuan Z
Toxicology 2019 Sep 1;425:152246
Toxicology 2019 Sep 1;425:152246
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
Comparison of hypoxic effects induced by chemical and physical hypoxia on cardiomyocytes.
Zhao RZ, Jiang S, Ru NY, Jiao B, Yu ZB
Canadian journal of physiology and pharmacology 2019 Oct;97(10):980-988
Canadian journal of physiology and pharmacology 2019 Oct;97(10):980-988
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L
International journal of oncology 2019 Oct;55(4):879-895
International journal of oncology 2019 Oct;55(4):879-895
The protective effect of Cordycepin on diabetic nephropathy through autophagy induction in vivo and in vitro.
Cao T, Xu R, Xu Y, Liu Y, Qi D, Wan Q
International urology and nephrology 2019 Oct;51(10):1883-1892
International urology and nephrology 2019 Oct;51(10):1883-1892
Linc01105 acts as an oncogene in the development of neuroblastoma.
Ye M, Ma J, Liu B, Liu X, Ma D, Dong K
Oncology reports 2019 Oct;42(4):1527-1538
Oncology reports 2019 Oct;42(4):1527-1538
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
Wang HT, Tong X, Zhang ZX, Sun YY, Yan W, Xu ZM, Fu WN
The FEBS journal 2019 Oct;286(19):3892-3908
The FEBS journal 2019 Oct;286(19):3892-3908
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Rapamycin Protects Spiral Ganglion Neurons from Gentamicin-Induced Degeneration In Vitro.
Guo S, Xu N, Chen P, Liu Y, Qi X, Liu S, Li C, Tang J
Journal of the Association for Research in Otolaryngology : JARO 2019 Oct;20(5):475-487
Journal of the Association for Research in Otolaryngology : JARO 2019 Oct;20(5):475-487
CircINHA resists granulosa cell apoptosis by upregulating CTGF as a ceRNA of miR-10a-5p in pig ovarian follicles.
Guo T, Zhang J, Yao W, Du X, Li Q, Huang L, Ma M, Li Q, Liu H, Pan Z
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Oct;1862(10):194420
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Oct;1862(10):194420
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Li F, Wu JT, Wang PF, Qu LZ
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
The protective effects of salvianolic acid A against hepatic ischemia-reperfusion injury via inhibiting expression of toll-like receptor 4 in rats.
Yang L, Jiang L, Jiang D, Liu B, Jin S
Archives of medical science : AMS 2019 Oct;15(6):1599-1607
Archives of medical science : AMS 2019 Oct;15(6):1599-1607
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, Liu K, Sun H
Pharmacological research 2019 Oct;148:104414
Pharmacological research 2019 Oct;148:104414
Overexpression of lncRNA WWTR1-AS1 associates with tumor aggressiveness and unfavorable survival in head-neck squamous cell carcinoma.
Li J, Li Z, Wu Y, Diao P, Zhang W, Wang Y, Yang J, Cheng J
Journal of cellular biochemistry 2019 Oct;120(10):18266-18277
Journal of cellular biochemistry 2019 Oct;120(10):18266-18277
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, Xu Y, Zhang J, Shao C
Scientific reports 2019 Oct 23;9(1):15221
Scientific reports 2019 Oct 23;9(1):15221
Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling.
Wu Y, Li Z, Zhang L, Liu G
Medical science monitor : international medical journal of experimental and clinical research 2019 Oct 2;25:7383-7390
Medical science monitor : international medical journal of experimental and clinical research 2019 Oct 2;25:7383-7390
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer.
Yuan SJ, Xu YH, Wang C, An HC, Xu HZ, Li K, Komatsu N, Zhao L, Chen X
Journal of nanobiotechnology 2019 Oct 17;17(1):110
Journal of nanobiotechnology 2019 Oct 17;17(1):110
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma.
Xu R, Li Y, Yan H, Zhang E, Huang X, Chen Q, Chen J, Qu J, Liu Y, He J, Yi Q, Cai Z
Cell death & disease 2019 Oct 14;10(10):781
Cell death & disease 2019 Oct 14;10(10):781
Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Yang HM, Li SZ
Brain sciences 2019 Oct 12;9(10)
Brain sciences 2019 Oct 12;9(10)
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, Liu X, Jiang J, Jiang Y, Li L
Toxicology letters 2019 Oct 1;313:77-90
Toxicology letters 2019 Oct 1;313:77-90
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
Li F, Zhang Y, Lu X, Shi J, Gong Q
Life sciences 2019 Oct 1;234:116739
Life sciences 2019 Oct 1;234:116739
Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.
Hua S, Liu J, Zhang Y, Li J, Zhang X, Dong L, Zhao Y, Fu X
Food science & nutrition 2019 Nov;7(11):3443-3451
Food science & nutrition 2019 Nov;7(11):3443-3451
The oncogenic role of NKAP in the growth and invasion of colon cancer cells.
Shu W, Liu G, Dai Y, Feng A, Chen Z, Han J, Li X
Oncology reports 2019 Nov;42(5):2130-2138
Oncology reports 2019 Nov;42(5):2130-2138
Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis.
Gong DJ, Wang L, Yang YY, Zhang JJ, Liu XH
Renal failure 2019 Nov;41(1):750-761
Renal failure 2019 Nov;41(1):750-761
Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice.
Huang ZB, Zheng YX, Li N, Cai SL, Huang Y, Wang J, Hu XW, Wang Y, Wu J, Fan XG
Acta pharmacologica Sinica 2019 Nov;40(11):1404-1411
Acta pharmacologica Sinica 2019 Nov;40(11):1404-1411
FoxD2-AS1 is a prognostic factor in glioma and promotes temozolomide resistance in a O(6)-methylguanine-DNA methyltransferase-dependent manner.
Shangguan W, Lv X, Tian N
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2019 Nov;23(6):475-482
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2019 Nov;23(6):475-482
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Zeng Q, He S, Zhong L, Wang L, Cheng F, Zhang H, Hui J, Wei A
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Sun K, Luo J, Jing X, Guo J, Yao X, Hao X, Ye Y, Liang S, Lin J, Wang G, Guo F
Aging 2019 Nov 26;11(22):10513-10531
Aging 2019 Nov 26;11(22):10513-10531
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
Xu WN, Zheng HL, Yang RZ, Liu T, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
Zhou K, Chen H, Lin J, Xu H, Wu H, Bao G, Li J, Deng X, Shui X, Gao W, Ding J, Xiao J, Xu H
Cell death & disease 2019 Nov 18;10(12):872
Cell death & disease 2019 Nov 18;10(12):872
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Lin P, Cheng Y, Song S, Qiu J, Yi L, Cao Z, Li J, Cheng S, Wang J
Journal of virology 2019 Nov 15;93(22)
Journal of virology 2019 Nov 15;93(22)
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.
Huang H, Cao K, Kong Y, Yuan S, Liu H, Wang Y, Liu Y
Chemical science 2019 Nov 14;10(42):9721-9728
Chemical science 2019 Nov 14;10(42):9721-9728
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, Fan X, Guo C, Wu J
International immunopharmacology 2019 May;70:435-445
International immunopharmacology 2019 May;70:435-445
Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.
Zhu L, Li D, Chen C, Wang G, Shi J, Zhang F
Biotechnology and applied biochemistry 2019 May;66(3):465-471
Biotechnology and applied biochemistry 2019 May;66(3):465-471
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, Wang Y, Huang Y, Zhang J, Li Q
International journal of oncology 2019 May;54(5):1601-1612
International journal of oncology 2019 May;54(5):1601-1612
Astragaloside IV attenuates myocardial ischemia/reperfusion injury in rats via inhibition of calcium-sensing receptor-mediated apoptotic signaling pathways.
Yin B, Hou XW, Lu ML
Acta pharmacologica Sinica 2019 May;40(5):599-607
Acta pharmacologica Sinica 2019 May;40(5):599-607
Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway.
Zhou MF, Feng ZP, Ou YC, Peng JJ, Li K, Gong HD, Qiu BH, Liu YW, Wang YJ, Qi ST
CNS neuroscience & therapeutics 2019 May;25(5):562-574
CNS neuroscience & therapeutics 2019 May;25(5):562-574
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
Li Y, Zheng Q, Sun D, Cui X, Chen S, Bulbul A, Liu S, Yan Q
Journal of cellular physiology 2019 May;234(5):7435-7447
Journal of cellular physiology 2019 May;234(5):7435-7447
1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.
Fan J, Wu M, Wang J, Ren D, Zhao J, Yang G
Journal of cellular physiology 2019 May;234(5):6336-6349
Journal of cellular physiology 2019 May;234(5):6336-6349
Exogenous testosterone alleviates cardiac fibrosis and apoptosis via Gas6/Axl pathway in the senescent mice.
Chen FF, Song FQ, Chen YQ, Wang ZH, Li YH, Liu MH, Li Y, Song M, Zhang W, Zhao J, Zhong M
Experimental gerontology 2019 May;119:128-137
Experimental gerontology 2019 May;119:128-137
Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide.
Ren H, Yang H, Xie M, Wen Y, Liu Q, Li X, Liu J, Xu H, Tang W, Wang M
Archives of oral biology 2019 May;101:108-121
Archives of oral biology 2019 May;101:108-121
Suppressing the Na(+)/H(+) exchanger 1: a new sight to treat depression.
Deng X, Ji Z, Xu B, Guo L, Xu L, Qin T, Feng L, Ma Z, Fu Q, Qu R, Quo Q, Ma S
Cell death & disease 2019 May 8;10(5):370
Cell death & disease 2019 May 8;10(5):370
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Dkk1 exacerbates doxorubicin-induced cardiotoxicity by inhibiting the Wnt/β-catenin signaling pathway.
Liang L, Tu Y, Lu J, Wang P, Guo Z, Wang Q, Guo K, Lan R, Li H, Liu P
Journal of cell science 2019 May 16;132(10)
Journal of cell science 2019 May 16;132(10)
Synergistic effects of Pb and repeated heat pulse on developmental neurotoxicity in zebrafish.
Jin M, Ji X, Zhang B, Sheng W, Wang R, Liu K
Ecotoxicology and environmental safety 2019 May 15;172:460-470
Ecotoxicology and environmental safety 2019 May 15;172:460-470
Estrogen-related receptor-α mediates puromycin aminonucleoside-induced mesangial cell apoptosis and inflammatory injury.
Gong W, Song J, Chen X, Li S, Yu J, Xia W, Ding G, Zhang Y, Jia Z, Zhang A, Huang S
American journal of physiology. Renal physiology 2019 May 1;316(5):F906-F913
American journal of physiology. Renal physiology 2019 May 1;316(5):F906-F913
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
Organotypic slice culture based on in ovo electroporation for chicken embryonic central nervous system.
Yang C, Li X, Li S, Chai X, Guan L, Qiao L, Li H, Lin J
Journal of cellular and molecular medicine 2019 Mar;23(3):1813-1826
Journal of cellular and molecular medicine 2019 Mar;23(3):1813-1826
Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells.
Wu DD, Liu SY, Gao YR, Lu D, Hong Y, Chen YG, Dong PZ, Wang DY, Li T, Li HM, Ren ZG, Guo JC, He F, Ren XQ, Sun SY, Duan SF, Ji XY
Journal of cellular and molecular medicine 2019 Mar;23(3):1698-1713
Journal of cellular and molecular medicine 2019 Mar;23(3):1698-1713
Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.
Otsuka S, Sakakima H, Terashi T, Takada S, Nakanishi K, Kikuchi K
Brain structure & function 2019 Mar;224(2):727-738
Brain structure & function 2019 Mar;224(2):727-738
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, Wang J, Feng X
Pain physician 2019 Mar;22(2):155-164
Pain physician 2019 Mar;22(2):155-164
Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos.
Jin M, Xiao Z, Zhang S, Men X, Li X, Zhang B, Zhou T, Hsiao CD, Liu K
Chemosphere 2019 Mar;219:557-566
Chemosphere 2019 Mar;219:557-566
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Overexpression of Pyruvate Dehydrogenase E1α Subunit Inhibits Warburg Effect and Induces Cell Apoptosis Through Mitochondria-Mediated Pathway in Hepatocellular Carcinoma.
Sun J, Li J, Guo Z, Sun L, Juan C, Zhou Y, Gu H, Yu Y, Hu Q, Kan Q, Yu Z
Oncology research 2019 Mar 29;27(4):407-414
Oncology research 2019 Mar 29;27(4):407-414
H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, Wei C, Xu C, Li H
Aging 2019 Mar 26;11(6):1745-1758
Aging 2019 Mar 26;11(6):1745-1758
PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma.
Wang DY, Hong Y, Chen YG, Dong PZ, Liu SY, Gao YR, Lu D, Li HM, Li T, Guo JC, He F, Ren XQ, Sun SY, Wu DD, Duan SF, Ji XY
Oncogenesis 2019 Mar 14;8(3):22
Oncogenesis 2019 Mar 14;8(3):22
Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy.
Li TF, Xu YH, Li K, Wang C, Liu X, Yue Y, Chen Z, Yuan SJ, Wen Y, Zhang Q, Han M, Komatsu N, Zhao L, Chen X
Acta biomaterialia 2019 Mar 1;86:381-394
Acta biomaterialia 2019 Mar 1;86:381-394
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Li YM, Zhang J, Su LJ, Kellum JA, Peng ZY
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.
Terashi T, Otsuka S, Takada S, Nakanishi K, Ueda K, Sumizono M, Kikuchi K, Sakakima H
Neurological research 2019 Jun;41(6):510-518
Neurological research 2019 Jun;41(6):510-518
Iron chelation effect of curcumin and baicalein on aplastic anemia mouse model with iron overload.
Dijiong W, Xiaowen W, Linlong X, Wenbin L, Huijin H, Baodong Y, Yuhong Z
Iranian journal of basic medical sciences 2019 Jun;22(6):660-668
Iranian journal of basic medical sciences 2019 Jun;22(6):660-668
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
Deng C, Li J, Li L, Sun F, Xie J
Experimental and therapeutic medicine 2019 Jun;17(6):4517-4521
Experimental and therapeutic medicine 2019 Jun;17(6):4517-4521
PKCδ contributes to oxidative stress-induced apoptosis in porcine ovarian granulosa cells via activating JNK.
Liu S, Shen M, Li C, Wei Y, Meng X, Li R, Cao Y, Wu W, Liu H
Theriogenology 2019 Jun;131:89-95
Theriogenology 2019 Jun;131:89-95
Potent and specific MTH1 inhibitors targeting gastric cancer.
Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, Ma J, Zhao L, Wang J, Jiang G, Wan X, Adam Goscinski M, Ding L, Zheng Y, Li W, Liu H, Suo Z, Zhao W
Cell death & disease 2019 Jun 4;10(6):434
Cell death & disease 2019 Jun 4;10(6):434
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, Pan Y, Bai Y, Shao C
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Cells 2019 Jun 18;8(6)
Cells 2019 Jun 18;8(6)
Modulation of PTEN by hexarelin attenuates coronary artery ligation-induced heart failure in rats.
Agbo E, Liu D, Li M, Saahene RO, Chen L, Zhao L, Wang Y, Tian G
Turkish journal of medical sciences 2019 Jun 18;49(3):945-958
Turkish journal of medical sciences 2019 Jun 18;49(3):945-958
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, Li S, Yu G, Yang J
Toxicology 2019 Jun 15;422:1-13
Toxicology 2019 Jun 15;422:1-13
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Dong S, Ji J, Hu L, Wang H
Life sciences 2019 Jun 15;227:20-29
Life sciences 2019 Jun 15;227:20-29
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y
Cell death & disease 2019 Jun 11;10(6):457
Cell death & disease 2019 Jun 11;10(6):457
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Lu GQ, Li XY, Mohamed O K, Wang D, Meng FH
European journal of medicinal chemistry 2019 Jun 1;171:282-296
European journal of medicinal chemistry 2019 Jun 1;171:282-296
S-allyl-l-cysteine (SAC) protects hepatocytes from alcohol-induced apoptosis.
Chen P, Hu M, Liu F, Yu H, Chen C
FEBS open bio 2019 Jul;9(7):1327-1336
FEBS open bio 2019 Jul;9(7):1327-1336
Synthesized glucocorticoid-induced leucine zipper peptide inhibits photoreceptor apoptosis and protects retinal function in light-induced retinal degeneration model.
Gu R, Tang W, Lei B, Jiang C, Song F, Xu G
Clinical & experimental ophthalmology 2019 Jul;47(5):646-657
Clinical & experimental ophthalmology 2019 Jul;47(5):646-657
Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.
Wei W, Lan XB, Liu N, Yang JM, Du J, Ma L, Zhang WJ, Niu JG, Sun T, Yu JQ
Neurochemical research 2019 Jul;44(7):1582-1592
Neurochemical research 2019 Jul;44(7):1582-1592
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Du W, Wang N, Li F, Jia K, An J, Liu Y, Wang Y, Zhu L, Zhao S, Hao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
Tian L, Su CP, Wang Q, Wu FJ, Bai R, Zhang HM, Liu JY, Lu WJ, Wang W, Lan F, Guo SZ
Journal of cellular and molecular medicine 2019 Jul;23(7):4666-4678
Journal of cellular and molecular medicine 2019 Jul;23(7):4666-4678
Activation of TRPC6 channels contributes to (+)-conocarpan-induced apoptotic cell death in HK-2 cells.
Yang G, Ma H, Wu Y, Zhou B, Zhang C, Chai C, Cao Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:281-290
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:281-290
Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis.
Zhou X, Chu X, Yuan H, Qiu J, Zhao C, Xin D, Li T, Ma W, Wang H, Wang Z, Wang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108818
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108818
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Yin F, Yan J, Zhao Y, Guo KJ, Zhang ZL, Li AP, Meng CY, Guo L
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Dong Q, Yang B, Han JG, Zhang MM, Liu W, Zhang X, Yu HL, Liu ZG, Zhang SH, Li T, Wu DD, Ji XY, Duan SF
Cancer letters 2019 Jul 28;455:60-72
Cancer letters 2019 Jul 28;455:60-72
Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction.
Zhang TY, Chen HY, Cao JL, Xiong HL, Mo XB, Li TL, Kang XZ, Zhao JH, Yin B, Zhao X, Huang CH, Yuan Q, Xue D, Xia NS, Yuan YA
Nature communications 2019 Jul 19;10(1):3192
Nature communications 2019 Jul 19;10(1):3192
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L, Sun J, Chen X, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, Hu J, Yang G, Jiang S
Life sciences 2019 Jul 15;229:187-199
Life sciences 2019 Jul 15;229:187-199
Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity.
Li XY, Zhang TJ, Kamara MO, Lu GQ, Xu HL, Wang DP, Meng FH
Cell death & disease 2019 Jul 11;10(7):532
Cell death & disease 2019 Jul 11;10(7):532
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, Shi L, Du L, Liu G, Zhang C, Xu X, Kang X, Zhen Y, Zhang S
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Yang Q, Lin J, Zhang H, Liu Y, Kan M, Xiu Z, Chen X, Lan X, Li X, Shi X, Li N, Qu X
Journal of molecular neuroscience : MN 2019 Jan;67(1):62-71
Journal of molecular neuroscience : MN 2019 Jan;67(1):62-71
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Yu H, Fu QR, Huang ZJ, Lin JY, Chen QX, Wang Q, Shen DY
Oncology reports 2019 Jan;41(1):213-223
Oncology reports 2019 Jan;41(1):213-223
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Gong Z, Kuang Z, Li H, Li C, Ali MK, Huang F, Li P, Li Q, Huang X, Ren S, Li J, Xie J
Cellular immunology 2019 Jan;335:41-50
Cellular immunology 2019 Jan;335:41-50
Downregulation of microRNA-196a attenuates ischemic brain injury in rats by directly targeting HMGA1.
Zhang DL, Liu X, Wang Q, Li N, Wu SH, Wang C
European review for medical and pharmacological sciences 2019 Jan;23(2):740-748
European review for medical and pharmacological sciences 2019 Jan;23(2):740-748
Radioprotective effects of roxadustat (FG-4592) in haematopoietic system.
Zhang P, Du J, Zhao H, Cheng Y, Dong S, Yang Y, Li B, Gao F, Sun X, Cai J, Liu C
Journal of cellular and molecular medicine 2019 Jan;23(1):349-356
Journal of cellular and molecular medicine 2019 Jan;23(1):349-356
Nischarin attenuates apoptosis induced by oxidative stress in PC12 cells.
Guo Z, Yuan Y, Guo Y, Wang H, Song C, Huang M
Experimental and therapeutic medicine 2019 Jan;17(1):663-670
Experimental and therapeutic medicine 2019 Jan;17(1):663-670
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
Zheng L, Han X, Hu Y, Zhao X, Yin L, Xu L, Qi Y, Xu Y, Han X, Liu K, Peng J
Pharmacological research 2019 Jan;139:431-439
Pharmacological research 2019 Jan;139:431-439
Estrogen receptor variant ER-α36 promotes tamoxifen agonist activity in glioblastoma cells.
Qu C, Ma J, Zhang Y, Han C, Huang L, Shen L, Li H, Wang X, Liu J, Zou W
Cancer science 2019 Jan;110(1):221-234
Cancer science 2019 Jan;110(1):221-234
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.
Chen Y, Wang D, Peng H, Chen X, Han X, Yu J, Wang W, Liang L, Liu Z, Zheng Y, Hu J, Yang L, Li J, Zhou H, Cui X, Li F
Molecular cancer 2019 Jan 4;18(1):1
Molecular cancer 2019 Jan 4;18(1):1
Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway.
Chen L, Yang G, Dong H
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 3;25:77-86
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 3;25:77-86
A Novel Mutant of rLj-RGD3 (rLj-112) Suppressed the Proliferation and Metastasis of B16 Cells through the EGFR Signaling Pathway.
Zheng YY, Xiao R, Zhang LX, Yan HJ, Wang JH, Lv L
Marine drugs 2019 Jan 23;17(2)
Marine drugs 2019 Jan 23;17(2)
Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis.
Li Z, Yu Y, Wang M, Xu H, Han B, Jiang P, Ma H, Li Y, Tian C, Zhou D, Li X, Ye X
Scientific reports 2019 Jan 16;9(1):146
Scientific reports 2019 Jan 16;9(1):146
A phenanthroline derivative enhances radiosensitivity of hepatocellular carcinoma cells by inducing mitochondria-dependent apoptosis.
Liu HM, Wu Q, Cao JQ, Wang X, Song Y, Mei WJ, Wang XC
European journal of pharmacology 2019 Jan 15;843:285-291
European journal of pharmacology 2019 Jan 15;843:285-291
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, Tian Y
Toxins 2019 Jan 15;11(1)
Toxins 2019 Jan 15;11(1)
Evaluation of Iodine-125 Interstitial Brachytherapy Using Micro-Positron Emission Tomography/Computed Tomography with 18F-Fluorodeoxyglucose in Hepatocellular Carcinoma HepG2 Xenografts.
Zhu Y, Dong M, Yang J, Zhang J
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 12;25:371-380
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 12;25:371-380
Role of ZIP8 in regulation of cisplatin sensitivity through Bcl-2.
Geng X, Liu L, Tsai KJ, Liu Z
Toxicology and applied pharmacology 2019 Jan 1;362:52-58
Toxicology and applied pharmacology 2019 Jan 1;362:52-58
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Liu X, Sun H
Inflammation 2019 Feb;42(1):64-80
Inflammation 2019 Feb;42(1):64-80
The protective role of IL-1Ra on intestinal ischemia reperfusion injury by anti-oxidative stress via Nrf2/HO-1 pathway in rat.
Jin C, Fu WL, Zhang DD, Xing WW, Xia WR, Wei Z, Zou MJ, Zhu XM, Xu DG
Biomedical journal 2019 Feb;42(1):36-45
Biomedical journal 2019 Feb;42(1):36-45
Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model.
Deng S, Nie ZG, Peng PJ, Liu Y, Xing S, Long LS, Peng H
Current medical science 2019 Feb;39(1):75-80
Current medical science 2019 Feb;39(1):75-80
Oxymatrine Inhibits Bocavirus MVC Replication, Reduces Viral Gene Expression and Decreases Apoptosis Induced by Viral Infection.
Ding Y, Li N, Sun J, Zhang L, Guo J, Hao X, Sun Y
Virologica Sinica 2019 Feb;34(1):78-87
Virologica Sinica 2019 Feb;34(1):78-87
MiR-15b is a key regulator of proliferation and apoptosis of chondrocytes from patients with condylar hyperplasia by targeting IGF1, IGF1R and BCL2.
Cao P, Feng Y, Deng M, Li J, Cai H, Meng Q, Fang W, Li Y, Ke J, Long X
Osteoarthritis and cartilage 2019 Feb;27(2):336-346
Osteoarthritis and cartilage 2019 Feb;27(2):336-346
DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats.
Duan J, Deng T, Kang J, Chen M
Environmental pollution (Barking, Essex : 1987) 2019 Feb;245:316-324
Environmental pollution (Barking, Essex : 1987) 2019 Feb;245:316-324
Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids.
Ma H, Yu Y, Wang M, Li Z, Xu H, Tian C, Zhang J, Ye X, Li X
Apoptosis : an international journal on programmed cell death 2019 Feb;24(1-2):168-183
Apoptosis : an international journal on programmed cell death 2019 Feb;24(1-2):168-183
Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis.
Wang N, Li R, Xue M
Journal of cellular and molecular medicine 2019 Feb;23(2):852-864
Journal of cellular and molecular medicine 2019 Feb;23(2):852-864
Role of mitochondrial damage in Cr(VI)‑induced endoplasmic reticulum stress in L‑02 hepatocytes.
Liang Q, Zhang Y, Huang M, Xiao Y, Xiao F
Molecular medicine reports 2019 Feb;19(2):1256-1265
Molecular medicine reports 2019 Feb;19(2):1256-1265
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Zhao B, Hu T
Oncology letters 2019 Feb;17(2):1939-1945
Oncology letters 2019 Feb;17(2):1939-1945
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Cheng B, Zhong JP, Wu FX, Li GL, Ruan QX, Luo G, Jiang H
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Chen Z, Wang C, Li TF, Li K, Yue Y, Liu X, Xu HZ, Wen Y, Zhang Q, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway.
Li L, Liu M, Zhang Z, Zhang W, Liu N, Sheng X, Wei P
Biological research 2019 Feb 27;52(1):8
Biological research 2019 Feb 27;52(1):8
Long non-coding RNA TP73‑AS1 promotes colorectal cancer proliferation by acting as a ceRNA for miR‑103 to regulate PTEN expression.
Jia Z, Peng J, Yang Z, Chen J, Liu L, Luo D, He P
Gene 2019 Feb 15;685:222-229
Gene 2019 Feb 15;685:222-229
κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway.
Cui Y, Feng N, Gu X, Fu F, Li J, Guo H, Liu Y, Zhang S, Li J, Wang Y, Jia M, Yang L, Zhang F, Wang Y, Fan R, Pei J
Lipids in health and disease 2019 Feb 14;18(1):52
Lipids in health and disease 2019 Feb 14;18(1):52
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, Xu J
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, Zhao X
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Wang S, Hu H, Zhong B, Shi D, Qing X, Cheng C, Deng X, Zhang Z, Shao Z
Cancer medicine 2019 Dec;8(17):7345-7358
Cancer medicine 2019 Dec;8(17):7345-7358
Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damage.
Li Y, Wang C, Liu Y, You J, Su G
Tissue & cell 2019 Dec;61:98-108
Tissue & cell 2019 Dec;61:98-108
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, Xu D, Fan Q, Wang T, Xiao Y, Chen W, Shan Z, Huang Z, Wang Q
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
Yonsei medical journal 2019 Dec;60(12):1195-1202
Yonsei medical journal 2019 Dec;60(12):1195-1202
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Li N, Guo X, Liu L, Wang L, Cheng R
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Restoration of p53 acetylation by HDAC inhibition permits the necrosis/apoptosis switch of pancreatic ainar cell during experimental pancreatitis in mice.
Hu Y, Dai J, Zong G, Xiao J, Guo X, Dai Y, Lu Z, Wan R
Journal of cellular physiology 2019 Dec;234(12):21988-21998
Journal of cellular physiology 2019 Dec;234(12):21988-21998
Effects of kojic acid on boar sperm quality and anti-bacterial activity during liquid preservation at 17 C.
Shaoyong W, Li Q, Ren Z, Xiao J, Diao Z, Yang G, Pang W
Theriogenology 2019 Dec;140:124-135
Theriogenology 2019 Dec;140:124-135
miR-885-5p Negatively Regulates Warburg Effect by Silencing Hexokinase 2 in Liver Cancer.
Xu F, Yan JJ, Gan Y, Chang Y, Wang HL, He XX, Zhao Q
Molecular therapy. Nucleic acids 2019 Dec 6;18:308-319
Molecular therapy. Nucleic acids 2019 Dec 6;18:308-319
The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5.
Yang D, Yu J, Liu HB, Yan XQ, Hu J, Yu Y, Guo J, Yuan Y, Du ZM
Cell death & disease 2019 Dec 2;10(12):908
Cell death & disease 2019 Dec 2;10(12):908
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H
Aging 2019 Dec 16;11(24):12532-12545
Aging 2019 Dec 16;11(24):12532-12545
Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation.
Liu L, Chen H, Jin J, Tang Z, Yin P, Zhong D, Li G
Life sciences 2019 Dec 15;239:117036
Life sciences 2019 Dec 15;239:117036
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, Feng J
Life sciences 2019 Dec 15;239:117020
Life sciences 2019 Dec 15;239:117020
LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages.
Liu H, Kai L, Du H, Wang X, Wang Y
Cells 2019 Dec 12;8(12)
Cells 2019 Dec 12;8(12)
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Assani G, Segbo J, Yu X, Yessoufou A, Xiong Y, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis.
Yang CH, Xu JH, Ren QC, Duan T, Mo F, Zhang W
Journal of pineal research 2019 Aug;67(1):e12569
Journal of pineal research 2019 Aug;67(1):e12569
Soluble CXCL16 promotes TNF-α-induced apoptosis in DLBCL via the AMAD10-NF-κB regulatory feedback loop.
Yang H, Qiu B, Chen S, Xun Y, Pan Y, Chen M, Li WX, Liao W, El-Ashram S, Yang A, Liu F
Cell biology international 2019 Aug;43(8):863-874
Cell biology international 2019 Aug;43(8):863-874
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Liu P, Zhang HM, Hu K, Zhou XF, Tang S
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Journal of cellular physiology 2019 Aug;234(8):13534-13543
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, You S, Wu S, Sun Y
Molecular medicine reports 2019 Aug;20(2):1561-1568
Molecular medicine reports 2019 Aug;20(2):1561-1568
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
Wen J, Xu B, Sun Y, Lian M, Li Y, Lin Y, Chen D, Diao Y, Almoiliqy M, Wang L
Pharmacological research 2019 Aug;146:104308
Pharmacological research 2019 Aug;146:104308
Sinoporphyrin sodium based sonodynamic therapy induces anti-tumor effects in hepatocellular carcinoma and activates p53/caspase 3 axis.
Li E, Sun Y, Lv G, Li Y, Zhang Z, Hu Z, Cao W
The international journal of biochemistry & cell biology 2019 Aug;113:104-114
The international journal of biochemistry & cell biology 2019 Aug;113:104-114
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, Chen W, Gui R
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.
Ming-Yan Y, Jing Z, Shu-Qin G, Xiao-Liang B, Zhi-Hong L, Xue Z
Bioscience reports 2019 Aug 30;39(8)
Bioscience reports 2019 Aug 30;39(8)
Resveratrol induces apoptosis of benign prostatic hyperplasia epithelial cell line (BPH-1) through p38 MAPK-FOXO3a pathway.
Li C, Hu WL, Lu MX, Xiao GF
BMC complementary and alternative medicine 2019 Aug 29;19(1):233
BMC complementary and alternative medicine 2019 Aug 29;19(1):233
VceC Mediated IRE1 Pathway and Inhibited CHOP-induced Apoptosis to Support Brucella Replication in Goat Trophoblast Cells.
Zhi F, Zhou D, Bai F, Li J, Xiang C, Zhang G, Jin Y, Wang A
International journal of molecular sciences 2019 Aug 22;20(17)
International journal of molecular sciences 2019 Aug 22;20(17)
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Wu T, Jiang N, Ji Z, Shi G
Life sciences 2019 Aug 15;231:116569
Life sciences 2019 Aug 15;231:116569
The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma.
Zhu L, Xia C, Wu L, Zhang Y, Liu J, Chen Y, Liu J, Xiao Y, Nie K, Huang L, Qu N, Yu H
Cell communication and signaling : CCS 2019 Aug 13;17(1):92
Cell communication and signaling : CCS 2019 Aug 13;17(1):92
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Jin J, Sun H, Liu D, Wang H, Liu Q, Chen H, Zhong D, Li G
Neuroscience 2019 Aug 10;413:123-134
Neuroscience 2019 Aug 10;413:123-134
Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells.
Li H, Dai Y, Luo Z, Nie D
Molecular biology reports 2019 Apr;46(2):2029-2038
Molecular biology reports 2019 Apr;46(2):2029-2038
Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals.
Li D, Cai Z, Wu J, Zhang Y
Neurological research 2019 Apr;41(4):369-377
Neurological research 2019 Apr;41(4):369-377
Protective effects of ethyl gallate on H(2)O(2)-induced mitochondrial dysfunction in PC12 cells.
Chen L, Wu X, Shen T, Wang X, Wang S, Wang J, Ren D
Metabolic brain disease 2019 Apr;34(2):545-555
Metabolic brain disease 2019 Apr;34(2):545-555
Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro.
Jing Z, Wang C, Yang Q, Wei X, Jin Y, Meng Q, Liu Q, Liu Z, Ma X, Liu K, Sun H, Liu M
Journal of cellular physiology 2019 Apr;234(4):4472-4490
Journal of cellular physiology 2019 Apr;234(4):4472-4490
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Pan JH, Zhou H, Zhu SB, Huang JL, Zhao XX, Ding H, Qin L, Pan YL
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Li XY, Liu YR, Zhou JH, Li W, Guo HH, Ma HP
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
Deficiency of TPPP2, a factor linked to oligoasthenozoospermia, causes subfertility in male mice.
Zhu F, Yan P, Zhang J, Cui Y, Zheng M, Cheng Y, Guo Y, Yang X, Guo X, Zhu H
Journal of cellular and molecular medicine 2019 Apr;23(4):2583-2594
Journal of cellular and molecular medicine 2019 Apr;23(4):2583-2594
Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem.
Pan H, Wang H, Yu J, Huang X, Hao Y, Zhang C, Ji W, Yang M, Gong X, Wu X, Chang J
Biomaterials 2019 Apr;199:22-31
Biomaterials 2019 Apr;199:22-31
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, Sun H, Qi Y, Fang L, Liu K, Peng J
British journal of pharmacology 2019 Apr;176(7):919-937
British journal of pharmacology 2019 Apr;176(7):919-937
Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling.
Li XG, Du JH, Lu Y, Lin XJ
Neural regeneration research 2019 Apr;14(4):721-727
Neural regeneration research 2019 Apr;14(4):721-727
Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.
Lu L, Chen G, Yang J, Ma Z, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108625
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108625
Knockdown MTMR14 promotes cell apoptosis and inhibits migration in liver cancer cells.
Li Z, Rong L, Lian H, Cheng J, Wu X, Li X
Gene 2019 Apr 5;691:106-113
Gene 2019 Apr 5;691:106-113
Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice.
Xu B, Lian S, Guo JR, Wang JF, Zhang LP, Li SZ, Yang HM
Neuroscience letters 2019 Apr 23;699:97-102
Neuroscience letters 2019 Apr 23;699:97-102
Effects of agomelatine in rotenone-induced Parkinson's disease in rats.
Günaydın C, Avcı B, Bozkurt A, Önger ME, Balcı H, Bilge SS
Neuroscience letters 2019 Apr 23;699:71-76
Neuroscience letters 2019 Apr 23;699:71-76
Effects of 220 MHz Pulsed Modulated Radiofrequency Field on the Sperm Quality in Rats.
Guo L, Lin JJ, Xue YZ, An GZ, Zhang JP, Zhang KY, He W, Wang H, Li W, Ding GR
International journal of environmental research and public health 2019 Apr 10;16(7)
International journal of environmental research and public health 2019 Apr 10;16(7)
PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
Tian W, Guo HS, Li CY, Cao W, Wang XY, Mo D, Hao XW, Feng YD, Sun Y, Lei F, Zhang HN, Zhao MG, Li XQ
Toxicology and applied pharmacology 2019 Apr 1;368:26-36
Toxicology and applied pharmacology 2019 Apr 1;368:26-36
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Duan YM, Jin Y, Guo ML, Duan LX, Wang JG
Journal of Cancer 2018;9(15):2723-2733
Journal of Cancer 2018;9(15):2723-2733
Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation.
Yang L, Guo Y, Huang M, Wu X, Li X, Chen G, Li Y, Bai J
Frontiers in neurology 2018;9:49
Frontiers in neurology 2018;9:49
Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model.
Deng S, Zhou JL, Fang HS, Nie ZG, Chen S, Peng H
Frontiers in physiology 2018;9:1787
Frontiers in physiology 2018;9:1787
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Mao J, Yi M, Wang R, Huang Y, Chen M
Frontiers in pharmacology 2018;9:1469
Frontiers in pharmacology 2018;9:1469
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, Li S, Wang Y, Lin D, Gao W, Kong J, Xu H, Zhou K
Frontiers in pharmacology 2018;9:1178
Frontiers in pharmacology 2018;9:1178
circEPSTI1 as a Prognostic Marker and Mediator of Triple-Negative Breast Cancer Progression.
Chen B, Wei W, Huang X, Xie X, Kong Y, Dai D, Yang L, Wang J, Tang H, Xie X
Theranostics 2018;8(14):4003-4015
Theranostics 2018;8(14):4003-4015
Icariside II, a Phosphodiesterase-5 Inhibitor, Attenuates Beta-Amyloid-Induced Cognitive Deficits via BDNF/TrkB/CREB Signaling.
Liu S, Li X, Gao J, Liu Y, Shi J, Gong Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(3):985
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(3):985
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Shen D, Tian L, Shen T, Sun H, Liu P
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Zhai E, Liang W, Lin Y, Huang L, He X, Cai S, Chen J, Zhang N, Li J, Zhang Q, He Y, Zeng Z, Chen M, Xu L, Peng S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(2):879-892
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(2):879-892
MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1.
Tian ZQ, Jiang H, Lu ZB
Cellular & molecular biology letters 2018;23:41
Cellular & molecular biology letters 2018;23:41
The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells.
Wu W, Nie L, Zhang L, Li Y
Cellular & molecular biology letters 2018;23:37
Cellular & molecular biology letters 2018;23:37
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Zhang GY, Lu D, Duan SF, Gao YR, Liu SY, Hong Y, Dong PZ, Chen YG, Li T, Wang DY, Cheng XS, He F, Wei JS, Li GY, Zhang QY, Wu DD, Ji XY
Oxidative medicine and cellular longevity 2018;2018:9647809
Oxidative medicine and cellular longevity 2018;2018:9647809
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, Chen K, Xia Y, Niu P, Xu L, Wang F, Dai W, Zhou Y, Guo C
Mediators of inflammation 2018;2018:4032484
Mediators of inflammation 2018;2018:4032484
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, Niu P
PPAR research 2018;2018:3180396
PPAR research 2018;2018:3180396
Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link.
Zhang Y, Wang C, Jin Y, Yang Q, Meng Q, Liu Q, Dai Y, Cai L, Liu Z, Liu K, Sun H
Oxidative medicine and cellular longevity 2018;2018:2876350
Oxidative medicine and cellular longevity 2018;2018:2876350
Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.
Zhang HM, Liu P, Jiang C, Jin XQ, Liu RN, Li SQ, Zhao Y
PloS one 2018;13(2):e0193037
PloS one 2018;13(2):e0193037
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Xu L, Xing Q, Huang T, Zhou J, Liu T, Cui Y, Cheng T, Wang Y, Zhou X, Yang B, Yang GL, Zhang J, Zang X, Ma S, Guan F
Frontiers in cellular neuroscience 2018;12:498
Frontiers in cellular neuroscience 2018;12:498
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway.
Ding W, Ji T, Xiong W, Li T, Pu D, Liu R
Drug design, development and therapy 2018;12:3459-3469
Drug design, development and therapy 2018;12:3459-3469
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Li Q, Ma R, Zhang M
OncoTargets and therapy 2018;11:8435-8444
OncoTargets and therapy 2018;11:8435-8444
Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma.
Ye Y, Wu Y, Wang J
Cancer management and research 2018;10:6399-6407
Cancer management and research 2018;10:6399-6407
TMCO1 is essential for ovarian follicle development by regulating ER Ca(2+) store of granulosa cells.
Sun Z, Zhang H, Wang X, Wang QC, Zhang C, Wang JQ, Wang YH, An CQ, Yang KY, Wang Y, Gao F, Guo C, Tang TS
Cell death and differentiation 2018 Sep;25(9):1686-1701
Cell death and differentiation 2018 Sep;25(9):1686-1701
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
Huang Y, Hu Z
Journal of cellular physiology 2018 Sep;233(9):7480-7496
Journal of cellular physiology 2018 Sep;233(9):7480-7496
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation.
Zhou X, Yong L, Huang Y, Zhu S, Song X, Li B, Zhu J, Wang H
Journal of cellular physiology 2018 Sep;233(9):6902-6910
Journal of cellular physiology 2018 Sep;233(9):6902-6910
Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis.
Lin H, Wang T, Ruan Y, Liu K, Li H, Wang S, Li M, Liu J
The journal of sexual medicine 2018 Sep;15(9):1246-1259
The journal of sexual medicine 2018 Sep;15(9):1246-1259
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity.
Qin J, Shi H, Xu Y, Zhao F, Wang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:758-765
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:758-765
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Yi C, Wan X, Zhang Y, Fu F, Zhao C, Qin R, Wu H, Li Y, Huang Y
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Song XQ, Liu YH, Shao J, Zhang ZL, Xie CZ, Qiao X, Bao WG, Xu JY
European journal of medicinal chemistry 2018 Sep 5;157:188-197
European journal of medicinal chemistry 2018 Sep 5;157:188-197
Tumor-targeting core-shell structured nanoparticles for drug procedural controlled release and cancer sonodynamic combined therapy.
Wang L, Hu Y, Hao Y, Li L, Zheng C, Zhao H, Niu M, Yin Y, Zhang Z, Zhang Y
Journal of controlled release : official journal of the Controlled Release Society 2018 Sep 28;286:74-84
Journal of controlled release : official journal of the Controlled Release Society 2018 Sep 28;286:74-84
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo.
Yu G, Chen J, Li S, Pu P, Huang W, Zhao Y, Peng X, Wang R, Lei H
Life sciences 2018 Sep 1;208:325-332
Life sciences 2018 Sep 1;208:325-332
Knockdown of ribosomal protein S15A inhibits proliferation of breast cancer cells through induction of apoptosis in vitro.
Feng W, Liang C, Wang C, Yu X, Li Q, Yang H
Cytotechnology 2018 Oct;70(5):1315-1323
Cytotechnology 2018 Oct;70(5):1315-1323
Titanium dioxide nanoparticles induce mouse hippocampal neuron apoptosis via oxidative stress- and calcium imbalance-mediated endoplasmic reticulum stress.
He Q, Zhou X, Liu Y, Gou W, Cui J, Li Z, Wu Y, Zuo D
Environmental toxicology and pharmacology 2018 Oct;63:6-15
Environmental toxicology and pharmacology 2018 Oct;63:6-15
Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway.
Xu N, Fan W, Zhou X, Liu Y, Ma P, Qi S, Gu B
Metabolic brain disease 2018 Oct;33(5):1625-1633
Metabolic brain disease 2018 Oct;33(5):1625-1633
Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma.
Li TF, Li K, Zhang Q, Wang C, Yue Y, Chen Z, Yuan SJ, Liu X, Wen Y, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Biomaterials 2018 Oct;181:35-52
Biomaterials 2018 Oct;181:35-52
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca(2+)Production.
Wang J, Yang C, Yuan Z, Yi J, Wu J
International journal of molecular sciences 2018 Oct 27;19(11)
International journal of molecular sciences 2018 Oct 27;19(11)
β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors.
You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, Liu X, Xiao Y, Zhang J, Gong Y, Xie C
International journal of oncology 2018 Nov;53(5):2258-2268
International journal of oncology 2018 Nov;53(5):2258-2268
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Wang X, Liu W, Wang P, Li S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Antitumor activities of novel glycyrrhetinic acid-modified curcumin-loaded cationic liposomes in vitro and in H22 tumor-bearing mice.
Chang M, Wu M, Li H
Drug delivery 2018 Nov;25(1):1984-1995
Drug delivery 2018 Nov;25(1):1984-1995
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Mu Z, Sun Q
Molecular medicine reports 2018 Nov;18(5):4603-4610
Molecular medicine reports 2018 Nov;18(5):4603-4610
Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.
Wang Z, Ren J, Liu Q, Li J, Wu X, Wang W, Wu J, Wang G, Li J
Thrombosis research 2018 Nov;171:45-54
Thrombosis research 2018 Nov;171:45-54
Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway.
Qiao J, Wang WJ, Zhang Y
Oncology letters 2018 Nov;16(5):6417-6422
Oncology letters 2018 Nov;16(5):6417-6422
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Yue X, Li M, Chen D, Xu Z, Sun S
Experimental and therapeutic medicine 2018 Nov;16(5):3921-3928
Experimental and therapeutic medicine 2018 Nov;16(5):3921-3928
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Dong W, Yang B, Wang Y, Yuan J, Fan Y, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.
Wang J, Li H, Wang X, Shen T, Wang S, Ren D
Biochemical and biophysical research communications 2018 Nov 10;505(4):1015-1021
Biochemical and biophysical research communications 2018 Nov 10;505(4):1015-1021
Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.
Lai X, Su W, Zhao H, Yang S, Zeng T, Wu W, Wang D
FEBS open bio 2018 May;8(5):743-750
FEBS open bio 2018 May;8(5):743-750
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
Shi J, Li F, Yao X, Mou T, Xu Z, Han Z, Chen S, Li W, Yu J, Qi X, Liu H, Li G
Oncogene 2018 May;37(22):3022-3038
Oncogene 2018 May;37(22):3022-3038
Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury.
Duan HQ, Wu QL, Yao X, Fan BY, Shi HY, Zhao CX, Zhang Y, Li B, Sun C, Kong XH, Zhou XF, Feng SQ
CNS neuroscience & therapeutics 2018 May;24(5):429-438
CNS neuroscience & therapeutics 2018 May;24(5):429-438
Lenalidomide improvement of cisplatin antitumor efficacy on triple-negative breast cancer cells in vitro.
Yin LL, Wen XM, Lai QH, Li J, Wang XW
Oncology letters 2018 May;15(5):6469-6474
Oncology letters 2018 May;15(5):6469-6474
Matrine reversed multidrug resistance of breast cancer MCF-7/ADR cells through PI3K/AKT signaling pathway.
Zhou BG, Wei CS, Zhang S, Zhang Z, Gao HM
Journal of cellular biochemistry 2018 May;119(5):3885-3891
Journal of cellular biochemistry 2018 May;119(5):3885-3891
Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling pathway.
Fang Y, Liu G, Xie C, Qian K, Lei X, Liu Q, Liu G, Cao Z, Fu J, Du H, Liu S, Huang S, Hu J, Xu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 May;101:910-919
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 May;101:910-919
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.
Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, Niu M, Qaed E, Shopit A, Han G, Ma X, Peng J, Hu M, Tang Z
Free radical biology & medicine 2018 May 20;120:228-238
Free radical biology & medicine 2018 May 20;120:228-238
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Wu DD, Gao YR, Li T, Wang DY, Lu D, Liu SY, Hong Y, Ning HB, Liu JP, Shang J, Shi JF, Wei JS, Ji XY
BMC cancer 2018 May 2;18(1):499
BMC cancer 2018 May 2;18(1):499
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice.
Wei J, Wu H, Zhang H, Li F, Chen S, Hou B, Shi Y, Zhao L, Duan H
International journal of molecular medicine 2018 Mar;41(3):1608-1618
International journal of molecular medicine 2018 Mar;41(3):1608-1618
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Yu L, Wang S, Lin X, Lu Y, Gu P
Molecular medicine reports 2018 Mar;17(3):3972-3978
Molecular medicine reports 2018 Mar;17(3):3972-3978
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
Tang X, Liu B, Wang X, Yu Q, Fang R
International journal of molecular sciences 2018 Mar 14;19(3)
International journal of molecular sciences 2018 Mar 14;19(3)
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Che C, Liu J, Yang J, Ma L, Bai N, Zhang Q
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Wang Y, Xu H, Lu Z, Yu X, Lv C, Tian Y, Sui D
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Zhang Y, Li H, Yang X, Jin G, Zhang Y
International journal of biological macromolecules 2018 Jun;112:788-795
International journal of biological macromolecules 2018 Jun;112:788-795
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
Sun X, Huang S, Wang X, Zhang X, Wang X
Oncotarget 2018 Jun 8;9(44):27574-27584
Oncotarget 2018 Jun 8;9(44):27574-27584
Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Li XY, Liang JW, Mohamed O K, Zhang TJ, Lu GQ, Meng FH
European journal of medicinal chemistry 2018 Jun 25;154:267-279
European journal of medicinal chemistry 2018 Jun 25;154:267-279
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Han B, Jiang P, Liu W, Xu H, Li Y, Li Z, Ma H, Yu Y, Li X, Ye X
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6031-6041
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6031-6041
The orphan nuclear receptor NR4A1 attenuates oxidative stress-induced β cells apoptosis via up-regulation of glutathione peroxidase 1.
Yang Y, Xie F, Qin D, Zong C, Han F, Pu Z, Liu D, Li X, Zhang Y, Liu Y, Wang X
Life sciences 2018 Jun 15;203:225-232
Life sciences 2018 Jun 15;203:225-232
Dysfunction of DNA damage-inducible transcript 4 in the decidua is relevant to the pathogenesis of preeclampsia.
Yang J, Zhang Y, Tong J, Lv H, Zhang C, Chen ZJ
Biology of reproduction 2018 Jun 1;98(6):821-833
Biology of reproduction 2018 Jun 1;98(6):821-833
Adenovirus-mediated overexpression of sST2 attenuates cardiac injury in the rat with severe acute pancreatitis.
Li L, Sun Z, Xu C, Wu J, Liu G, Cui H, Chen H
Life sciences 2018 Jun 1;202:167-174
Life sciences 2018 Jun 1;202:167-174
The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma.
Zhao JF, Zhao Q, Hu H, Liao JZ, Lin JS, Xia C, Chang Y, Liu J, Guo AY, He XX
Molecular therapy. Nucleic acids 2018 Jun 1;11:538-553
Molecular therapy. Nucleic acids 2018 Jun 1;11:538-553
Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy.
Gong J, Jin J, Zhao L, Li Y, Li Y, He Q
International journal of molecular medicine 2018 Jul;42(1):115-122
International journal of molecular medicine 2018 Jul;42(1):115-122
Molecular targeting of glutaminase sensitizes ovarian cancer cells to chemotherapy.
Masamha CP, LaFontaine P
Journal of cellular biochemistry 2018 Jul;119(7):6136-6145
Journal of cellular biochemistry 2018 Jul;119(7):6136-6145
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Seminal plasma miR-192a: a biomarker predicting successful resolution of nonobstructive azoospermia following varicocele repair.
Zhi EL, Liang GQ, Li P, Chen HX, Tian RH, Xu P, Li Z
Asian journal of andrology 2018 Jul-Aug;20(4):396-399
Asian journal of andrology 2018 Jul-Aug;20(4):396-399
Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells.
Li Z, Chen B, Dong W, Xu W, Song M, Fang M, Guo J, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Jul 27;
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Jul 27;
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Lian S, Wang D, Xu B, Guo W, Wang L, Li W, Ji H, Wang J, Kong F, Zhen L, Li S, Zhang L, Guo J, Yang H
Behavioural brain research 2018 Jul 2;346:1-10
Behavioural brain research 2018 Jul 2;346:1-10
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.
Zhang J, Liu L, Wang J, Ren B, Zhang L, Li W
Journal of ethnopharmacology 2018 Jul 15;221:91-99
Journal of ethnopharmacology 2018 Jul 15;221:91-99
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Cheng Y, Zhao P, Wu S, Yang T, Chen Y, Zhang X, He C, Zheng C, Li K, Ma X, Xiang G
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.
Chen X, Wu Q, Jiang H, Wang J, Zhao Y, Xu Y, Zhu M
Acta biochimica et biophysica Sinica 2018 Jul 1;50(7):635-642
Acta biochimica et biophysica Sinica 2018 Jul 1;50(7):635-642
UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis.
Liu C, Xing J, Gao Y
Thoracic cancer 2018 Jan;9(1):105-111
Thoracic cancer 2018 Jan;9(1):105-111
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z
Journal of cellular physiology 2018 Jan;234(1):777-788
Journal of cellular physiology 2018 Jan;234(1):777-788
A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells.
Hsieh CH, Wang JP, Chiu CC, Liu CY, Yao CF, Fang K
Apoptosis : an international journal on programmed cell death 2018 Jan;23(1):1-15
Apoptosis : an international journal on programmed cell death 2018 Jan;23(1):1-15
Protective Effect of Selenoprotein X Against Oxidative Stress-Induced Cell Apoptosis in Human Hepatocyte (LO2) Cells via the p38 Pathway.
Tang JY, He AH, Jia G, Liu GM, Chen XL, Cai JY, Shang HY, Liao JQ, Zhao H
Biological trace element research 2018 Jan;181(1):44-53
Biological trace element research 2018 Jan;181(1):44-53
Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.
Luo S, Pan Z, Liu S, Yuan S, Yan N
Oncology letters 2018 Jan;15(1):483-488
Oncology letters 2018 Jan;15(1):483-488
The inhibitory effects of soybean isoflavones on testicular cell apoptosis in mice with type 2 diabetes.
Du Z, Qiu Z, Wang Z, Wang X
Experimental and therapeutic medicine 2018 Jan;15(1):305-309
Experimental and therapeutic medicine 2018 Jan;15(1):305-309
Tetrahydroxystilbene glucoside relieves the chronic inflammatory pain by inhibiting neuronal apoptosis, microglia activation, and GluN2B overexpression in anterior cingulate cortex.
Fan YF, Guan SY, Luo L, Li YJ, Yang L, Zhou XX, Guo GD, Zhao MG, Yang Q, Liu G
Molecular pain 2018 Jan-Dec;14:1744806918814367
Molecular pain 2018 Jan-Dec;14:1744806918814367
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
Zhang J, Yuan JP, Wang Q, Shao LH, Liu SP, Firestone RA, Hong YP, Li JG, Xin YC, Li Y
Oncotarget 2018 Jan 5;9(2):1957-1968
Oncotarget 2018 Jan 5;9(2):1957-1968
PLK1 protects against sepsis-induced intestinal barrier dysfunction.
Cao Y, Chen Q, Wang Z, Yu T, Wu J, Jiang X, Jin X, Lu W
Scientific reports 2018 Jan 18;8(1):1055
Scientific reports 2018 Jan 18;8(1):1055
Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling.
Cao YY, Yu J, Liu TT, Yang KX, Yang LY, Chen Q, Shi F, Hao JJ, Cai Y, Wang MR, Lu WH, Zhang Y
Cell death & disease 2018 Jan 16;9(2):17
Cell death & disease 2018 Jan 16;9(2):17
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365.
Min QH, Wang XZ, Zhang J, Chen QG, Li SQ, Liu XQ, Li J, Liu J, Yang WM, Jiang YH, Xu YM, Lin J, Gao QF, Sun F, Zhang L, Huang B
Experimental cell research 2018 Jan 15;362(2):386-393
Experimental cell research 2018 Jan 15;362(2):386-393
Inhibition of REDD1 Sensitizes Bladder Urothelial Carcinoma to Paclitaxel by Inhibiting Autophagy.
Zeng Q, Liu J, Cao P, Li J, Liu X, Fan X, Liu L, Cheng Y, Xiong W, Li J, Bo H, Zhu Y, Yang F, Hu J, Zhou M, Zhou Y, Zou Q, Zhou J, Cao K
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jan 15;24(2):445-459
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jan 15;24(2):445-459
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, Li Z, Ye X, Li X
Life sciences 2018 Jan 1;192:259-269
Life sciences 2018 Jan 1;192:259-269
Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitis.
Li J, Yang C, Zhang S, Liu S, Zhao L, Luo H, Chen Y, Huang W
International journal of molecular medicine 2018 Feb;41(2):899-907
International journal of molecular medicine 2018 Feb;41(2):899-907
HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3.
Luo J, Wang Z, Huang J, Yao Y, Sun Q, Wang J, Shen Y, Xu L, Ren B
Cancer science 2018 Feb;109(2):317-329
Cancer science 2018 Feb;109(2):317-329
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.
Deng F, Peng L, Li Z, Tan G, Liang E, Chen S, Zhao X, Zhi F
Cell death & disease 2018 Feb 2;9(2):153
Cell death & disease 2018 Feb 2;9(2):153
hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway.
Yin N, Wang Y, Lu X, Liu R, Zhang L, Zhao W, Yuan W, Luo Q, Wu H, Luan X, Zhang H
Stem cell research & therapy 2018 Feb 14;9(1):37
Stem cell research & therapy 2018 Feb 14;9(1):37
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Zhao W, Che C, Liu K, Zhang J, Jiang N, Yuan K, Zhao G
Cornea 2018 Dec;37(12):1579-1585
Cornea 2018 Dec;37(12):1579-1585
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Effects of mdig on proliferation and apoptosis of lung cancer cells.
Xu X, Cao L, Zhang Y, Lian H, Sun Z, Cui Y
Oncology letters 2018 Dec;16(6):7146-7151
Oncology letters 2018 Dec;16(6):7146-7151
Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.
Chen YA, Tzeng DTW, Huang YP, Lin CJ, Lo UG, Wu CL, Lin H, Hsieh JT, Tang CH, Lai CH
Cancers 2018 Dec 31;11(1)
Cancers 2018 Dec 31;11(1)
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153
Chemico-biological interactions 2018 Dec 25;296:145-153
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Liu B, Xu L, Dai EN, Tian JX, Li JM
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Yang Y, Yu S, Liu N, Xu H, Gong Y, Wu Y, Wang P, Su X, Liao Y, De Saeger S, Humpf HU, Wu A
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Canonical Transient Receptor Potential Channel 3 Contributes to Febrile Seizure Inducing Neuronal Cell Death and Neuroinflammation.
Sun D, Ma H, Ma J, Wang J, Deng X, Hu C, Deng X
Cellular and molecular neurobiology 2018 Aug;38(6):1215-1226
Cellular and molecular neurobiology 2018 Aug;38(6):1215-1226
Therapeutic effects of the novel subtype-selective histone deacetylase inhibitor chidamide on myeloma-associated bone disease.
He J, Chen Q, Gu H, Chen J, Zhang E, Guo X, Huang X, Yan H, He D, Yang Y, Zhao Y, Wang G, He H, Yi Q, Cai Z
Haematologica 2018 Aug;103(8):1369-1379
Haematologica 2018 Aug;103(8):1369-1379
Activation of neuronal N-methyl-D-aspartate receptor plays a pivotal role in Japanese encephalitis virus-induced neuronal cell damage.
Chen Z, Wang X, Ashraf U, Zheng B, Ye J, Zhou D, Zhang H, Song Y, Chen H, Zhao S, Cao S
Journal of neuroinflammation 2018 Aug 25;15(1):238
Journal of neuroinflammation 2018 Aug 25;15(1):238
Memantine can improve chronic ethanol exposure-induced spatial memory impairment in male C57BL/6 mice by reducing hippocampal apoptosis.
Wang X, Yu H, You J, Wang C, Feng C, Liu Z, Li Y, Wei R, Xu S, Zhao R, Wu X, Zhang G
Toxicology 2018 Aug 1;406-407:21-32
Toxicology 2018 Aug 1;406-407:21-32
Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells.
Ni YL, Hsieh CH, Wang JP, Fang K
Chemico-biological interactions 2018 Aug 1;291:137-143
Chemico-biological interactions 2018 Aug 1;291:137-143
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
Liu M, Li Y, Liang B, Li Z, Jiang Z, Chu C, Yang J
International journal of molecular medicine 2018 Apr;41(4):1867-1876
International journal of molecular medicine 2018 Apr;41(4):1867-1876
Endoplasmic Reticulum Stress Facilitates the Survival and Proliferation of Nucleus Pulposus Cells in TNF-α Stimulus by Activating Unfolded Protein Response.
Chen L, Liu L, Xie ZY, Wang F, Sinkemani A, Zhang C, Wang XH, Wang K, Hong X, Wu XT
DNA and cell biology 2018 Apr;37(4):347-358
DNA and cell biology 2018 Apr;37(4):347-358
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Liu DZ, Cheng Y, Cai RQ, Wang Bd WW, Cui H, Liu M, Zhang BL, Mei QB, Zhou SY
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003
PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways.
Yang BY, Song JW, Sun HZ, Xing JC, Yang ZH, Wei CY, Xu TY, Yu ZN, Zhang YN, Wang YF, Chang H, Xu ZP, Hou M, Ji MJ, Zhang YS
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:205-212
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:205-212
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Yin S, Du W, Wang F, Han B, Cui Y, Yang D, Chen H, Liu D, Liu X, Zhai X, Jiang C
Cancer biology & therapy 2018 Apr 3;19(4):260-270
Cancer biology & therapy 2018 Apr 3;19(4):260-270
The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress.
Zhang H, Zhang W, Jiao F, Li X, Zhang H, Wang L, Gong Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 28;24:2620-2630
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 28;24:2620-2630
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Cai Z, Zou Y, Hu H, Lu C, Sun W, Jiang L, Hu G
American journal of translational research 2017;9(5):2645-2655
American journal of translational research 2017;9(5):2645-2655
Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Guo Y, Peng Y, Gao D, Zhang M, Yang W, Linghu E, Herman JG, Fuks F, Dong G, Guo M
Clinical epigenetics 2017;9:116
Clinical epigenetics 2017;9:116
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Mehmood T, Maryam A, Tian X, Khan M, Ma T
Journal of Cancer 2017;8(18):3707-3717
Journal of Cancer 2017;8(18):3707-3717
The Targeted Antitumor Effects of C- PC/CMC-CD59sp Nanoparticles on HeLa Cells in Vitro and in Vivo.
Wang Y, Jiang L, Yin Q, Liu H, Liu G, Zhu G, Li B
Journal of Cancer 2017;8(15):3001-3013
Journal of Cancer 2017;8(15):3001-3013
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.
Uslusoy F, Nazıroğlu M, Çiğ B
Frontiers in physiology 2017;8:335
Frontiers in physiology 2017;8:335
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway.
Liu LS, Bai XQ, Gao Y, Wu Q, Ren Z, Li Q, Pan LH, He NY, Peng J, Tang ZH
Journal of Alzheimer's disease : JAD 2017;57(3):723-734
Journal of Alzheimer's disease : JAD 2017;57(3):723-734
Exogenous H2S Protects Against Diabetic Cardiomyopathy by Activating Autophagy via the AMPK/mTOR Pathway.
Yang F, Zhang L, Gao Z, Sun X, Yu M, Dong S, Wu J, Zhao Y, Xu C, Zhang W, Lu F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1168-1187
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1168-1187
Sulforaphane-cysteine-induced apoptosis via phosphorylated ERK1/2-mediated maspin pathway in human non-small cell lung cancer cells.
Lin K, Yang R, Zheng Z, Zhou Y, Geng Y, Hu Y, Wu S, Wu W
Cell death discovery 2017;3:17025
Cell death discovery 2017;3:17025
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168
Audiology & neuro-otology 2017;22(3):160-168
Therapy Effects of Wogonin on Ovarian Cancer Cells.
Ruibin J, Bo J, Danying W, Chihong Z, Jianguo F, Linhui G
BioMed research international 2017;2017:9381513
BioMed research international 2017;2017:9381513
Relaxin Attenuates Contrast-Induced Human Proximal Tubular Epithelial Cell Apoptosis by Activation of the PI3K/Akt Signaling Pathway In Vitro.
Xie XC, Cao Y, Yang X, Xu QH, Wei W, Wang M
BioMed research international 2017;2017:2869405
BioMed research international 2017;2017:2869405
MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS.
Chen Y, Li Y, Xu H, Li G, Ma Y, Pang YJ
African journal of traditional, complementary, and alternative medicines : AJTCAM 2017;14(2):348-355
African journal of traditional, complementary, and alternative medicines : AJTCAM 2017;14(2):348-355
Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.
Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z, Shen G
Drug design, development and therapy 2017;11:431-439
Drug design, development and therapy 2017;11:431-439
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Feng J, Zhang Q, Mo W, Wu L, Li S, Li J, Liu T, Xu S, Fan X, Guo C
Drug design, development and therapy 2017;11:1989-2006
Drug design, development and therapy 2017;11:1989-2006
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Wang B, Shen J, Wang J
OncoTargets and therapy 2017;10:5303-5309
OncoTargets and therapy 2017;10:5303-5309
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Zhang B, Liu Y, Liu D, Yang L
Journal of biosciences 2017 Sep;42(3):417-425
Journal of biosciences 2017 Sep;42(3):417-425
Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.
Chen F, Zhang H, Wang Z, Ding W, Zeng Q, Liu W, Huang C, He S, Wei A
The journal of sexual medicine 2017 Sep;14(9):1084-1094
The journal of sexual medicine 2017 Sep;14(9):1084-1094
Reactive oxygen species-driven mitochondrial injury induces apoptosis by teroxirone in human non-small cell lung cancer cells.
Wang JP, Hsieh CH, Liu CY, Lin KH, Wu PT, Chen KM, Fang K
Oncology letters 2017 Sep;14(3):3503-3509
Oncology letters 2017 Sep;14(3):3503-3509
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Wang J, Li D, Zhuang Y, Fu J, Li X, Shi Q, Ju X
Oncology letters 2017 Sep;14(3):3082-3088
Oncology letters 2017 Sep;14(3):3082-3088
Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression.
Xu F, Li X, Liu L, Xiao X, Zhang L, Zhang S, Lin P, Wang X, Wang Y, Li Q
Experimental and therapeutic medicine 2017 Sep;14(3):2216-2220
Experimental and therapeutic medicine 2017 Sep;14(3):2216-2220
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Liu L, Mao J, Wang Q, Zhang Z, Wu G, Tang Q, Zhao B, Li L, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Neuroprotective effect of G(14)-humanin on global cerebral ischemia/reperfusion by activation of SOCS3 - STAT3 - MCL-1 signal transduction pathway in rats.
Gao G, Fan H, Zhang X, Zhang F, Wu H, Qi F, Zhao L, Li Y
Neurological research 2017 Oct;39(10):895-903
Neurological research 2017 Oct;39(10):895-903
A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres.
Ni YL, Hsieh CH, Kim SH, Wang JP, Su CL, Yao CF, Fang K
Apoptosis : an international journal on programmed cell death 2017 Oct;22(10):1235-1245
Apoptosis : an international journal on programmed cell death 2017 Oct;22(10):1235-1245
Humanin analogue, S14G-humanin, has neuroprotective effects against oxygen glucose deprivation/reoxygenation by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathway.
Gao GS, Li Y, Zhai H, Bi JW, Zhang FS, Zhang XY, Fan SH
Experimental and therapeutic medicine 2017 Oct;14(4):3926-3934
Experimental and therapeutic medicine 2017 Oct;14(4):3926-3934
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.
Zhou H, Zheng L, Lu K, Gao Y, Guo L, Xu W, Wang X
Medical science monitor : international medical journal of experimental and clinical research 2017 Oct 7;23:4817-4825
Medical science monitor : international medical journal of experimental and clinical research 2017 Oct 7;23:4817-4825
Studies on the cytotoxicity and anticancer performance of heterocyclic hypervalent organobismuth(III) compounds.
Liu YP, Lei J, Tang LW, Peng Y, Au CT, Chen Y, Yin SF
European journal of medicinal chemistry 2017 Oct 20;139:826-835
European journal of medicinal chemistry 2017 Oct 20;139:826-835
Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.
Sheng N, Yan L, You W, Tan G, Gong J, Chen H, Yang Y, Hu L, Wang Z
Acta biochimica et biophysica Sinica 2017 Oct 1;49(10):926-934
Acta biochimica et biophysica Sinica 2017 Oct 1;49(10):926-934
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
Zhao Y, Jing Z, Lv J, Zhang Z, Lin J, Cao X, Zhao Z, Liu P, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:18-24
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:18-24
Cysteine-rich buccal gland protein suppressed the proliferation, migration and invasion of hela cells through akt pathway.
Han J, Liu Y, Jiang Q, Xiao R
IUBMB life 2017 Nov;69(11):856-866
IUBMB life 2017 Nov;69(11):856-866
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Tan MJ, Cao XW, Li PF, Zhai YZ, Zhou Y, Liu YJ, Zhao J, Wang FJ
Biotechnology and applied biochemistry 2017 Nov;64(6):918-926
Biotechnology and applied biochemistry 2017 Nov;64(6):918-926
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Peng Z, Gong X, Yang Y, Huang L, Zhang Q, Zhang P, Wan R, Zhang B
International immunopharmacology 2017 Nov;52:281-289
International immunopharmacology 2017 Nov;52:281-289
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Inhibited effects of CAPE-pNO(2) on cervical carcinoma in vivo and in vitro and its detected metabolites.
Yao X, Tang H, Ren Q, Zhao X, Zuo H, Li Z
Oncotarget 2017 Nov 7;8(55):94197-94209
Oncotarget 2017 Nov 7;8(55):94197-94209
Overexpression of T-box Transcription Factor 5 (TBX5) Inhibits Proliferation and Invasion in Non-Small Cell Lung Carcinoma Cells.
Ma R, Yang Y, Tu Q, Hu K
Oncology research 2017 Nov 2;25(9):1495-1504
Oncology research 2017 Nov 2;25(9):1495-1504
Losartan protects against cerebral ischemia/reperfusion-induced apoptosis through β-arrestin1-mediated phosphorylation of Akt.
Chen L, Ren Z, Wei X, Wang S, Wang Y, Cheng Y, Gao H, Liu H
European journal of pharmacology 2017 Nov 15;815:98-108
European journal of pharmacology 2017 Nov 15;815:98-108
Edaravone ameliorates compression-induced damage in rat nucleus pulposus cells.
Lin H, Ma X, Wang BC, Zhao L, Liu JX, Pu FF, Hu YQ, Hu HZ, Shao ZW
Life sciences 2017 Nov 15;189:76-83
Life sciences 2017 Nov 15;189:76-83
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, Tan N
Molecules (Basel, Switzerland) 2017 Nov 11;22(11)
Molecules (Basel, Switzerland) 2017 Nov 11;22(11)
Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells.
Huang Z, Yang G, Shen T, Wang X, Li H, Ren D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:623-631
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:623-631
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
Geniposide protects pancreatic β cells from high glucose-mediated injury by activation of AMP-activated protein kinase.
Liu C, Hao Y, Yin F, Zhang Y, Liu J
Cell biology international 2017 May;41(5):544-554
Cell biology international 2017 May;41(5):544-554
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Khan SH, Zhao D, Shah SZ, Hassan MF, Zhu T, Song Z, Zhou X, Yang L
Cellular and molecular neurobiology 2017 May;37(4):717-728
Cellular and molecular neurobiology 2017 May;37(4):717-728
EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways.
Liu S, Sun Z, Chu P, Li H, Ahsan A, Zhou Z, Zhang Z, Sun B, Wu J, Xi Y, Han G, Lin Y, Peng J, Tang Z
Apoptosis : an international journal on programmed cell death 2017 May;22(5):672-680
Apoptosis : an international journal on programmed cell death 2017 May;22(5):672-680
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, Wan L, Zhang Z, Zhang C, Qin X, Xiao M, Ye D, Liu Y, Han Z, Wang S, Mao L, Wei W, Chen W
The EMBO journal 2017 May 2;36(9):1243-1260
The EMBO journal 2017 May 2;36(9):1243-1260
Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells.
Yin K, Zhu R, Wang S, Zhao RC
Stem cells and development 2017 May 15;26(10):762-775
Stem cells and development 2017 May 15;26(10):762-775
7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
Zhu Y, Jiang Y, Shi L, Du L, Xu X, Wang E, Sun Y, Guo X, Zou B, Wang H, Wang C, Sun L, Zhen Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Mar;87:527-538
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Mar;87:527-538
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Yang W, Yang S, Zhang M, Gao D, He T, Guo M
Genes & cancer 2017 Mar;8(3-4):528-535
Genes & cancer 2017 Mar;8(3-4):528-535
The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice.
Liu G, Wang J, Deng XH, Ma PS, Li FM, Peng XD, Niu Y, Sun T, Li YX, Yu JQ
Cellular and molecular neurobiology 2017 Mar;37(2):339-349
Cellular and molecular neurobiology 2017 Mar;37(2):339-349
12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis.
Wang X, Sun YY, Zhao C, Qu FZ, Zhao YQ
European journal of pharmacology 2017 Mar 5;798:49-56
European journal of pharmacology 2017 Mar 5;798:49-56
Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways.
Wu D, Luo N, Wang L, Zhao Z, Bu H, Xu G, Yan Y, Che X, Jiao Z, Zhao T, Chen J, Ji A, Li Y, Lee GD
Scientific reports 2017 Mar 28;7(1):455
Scientific reports 2017 Mar 28;7(1):455
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice.
Shi GJ, Zheng J, Wu J, Qiao HQ, Chang Q, Niu Y, Sun T, Li YX, Yu JQ
Food & function 2017 Mar 22;8(3):1215-1226
Food & function 2017 Mar 22;8(3):1215-1226
Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice.
Wei H, Gao Z, Zheng L, Zhang C, Liu Z, Yang Y, Teng H, Hou L, Yin Y, Zou X
Marine drugs 2017 Mar 16;15(3)
Marine drugs 2017 Mar 16;15(3)
Exogenous H(2)S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, Sun A, Dong S, Wu J, Zhong X, Xu C, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway.
Xie XC, Zhao N, Xu QH, Yang X, Xia WK, Chen Q, Wang M, Fei X
Apoptosis : an international journal on programmed cell death 2017 Jun;22(6):769-776
Apoptosis : an international journal on programmed cell death 2017 Jun;22(6):769-776
Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines.
Wang Q, Ding W, Ding Y, Ma J, Qian Z, Shao J, Li Y
Oncotarget 2017 Jun 6;8(23):37594-37604
Oncotarget 2017 Jun 6;8(23):37594-37604
Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery.
Cai RQ, Liu DZ, Cui H, Cheng Y, Liu M, Zhang BL, Mei QB, Zhou SY
Oncotarget 2017 Jun 27;8(26):42772-42788
Oncotarget 2017 Jun 27;8(26):42772-42788
The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways.
Lu SY, Wang CY, Jin Y, Meng Q, Liu Q, Liu ZH, Liu KX, Sun HJ, Liu MZ
Scientific reports 2017 Jun 13;7(1):3331
Scientific reports 2017 Jun 13;7(1):3331
Bone marrow mesenchymal stem cells repair cadmium-induced rat testis injury by inhibiting mitochondrial apoptosis.
Wang YJ, Yan J, Zou XL, Guo KJ, Zhao Y, Meng CY, Yin F, Guo L
Chemico-biological interactions 2017 Jun 1;271:39-47
Chemico-biological interactions 2017 Jun 1;271:39-47
DKK3 regulates cell proliferation, apoptosis and collagen synthesis in keloid fibroblasts via TGF-β1/Smad signaling pathway.
Li Y, Liu H, Liang Y, Peng P, Ma X, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:174-180
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:174-180
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Ying C, Liu T, Ling H, Cheng M, Zhou X, Wang S, Mao Y, Chen L, Zhang R, Li W
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Sesamol attenuates oxidative stress, apoptosis and inflammation in focal cerebral ischemia/reperfusion injury.
Gao XJ, Xie GN, Liu L, Fu ZJ, Zhang ZW, Teng LZ
Experimental and therapeutic medicine 2017 Jul;14(1):841-847
Experimental and therapeutic medicine 2017 Jul;14(1):841-847
Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin.
Fang S, Qiu J, Wu Z, Bai T, Guo W
Oncotarget 2017 Jul 25;8(30):49783-49795
Oncotarget 2017 Jul 25;8(30):49783-49795
Hypertonic saline infusion suppresses apoptosis of hippocampal cells in a rat model of cardiopulmonary resuscitation.
Zhou X, Liu Y, Huang Y, Zhu S, Zhu J, Wang R
Scientific reports 2017 Jul 19;7(1):5783
Scientific reports 2017 Jul 19;7(1):5783
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
Su WC, Lin YF, Yu XP, Wang YX, Lin XD, Su QZ, Shen DY, Chen QX
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.
Gu R, Tang W, Lei B, Ding X, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jul 1;58(9):3656-3668
Investigative ophthalmology & visual science 2017 Jul 1;58(9):3656-3668
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Wang EX, Zou BY, Shi L, Du LY, Zhu YY, Jiang YM, Ma XD, Kang XH, Wang CY, Zhen YH, Sun LD
Life sciences 2017 Jul 1;180:102-113
Life sciences 2017 Jul 1;180:102-113
Cortistatin Improves Cardiac Function After Acute Myocardial Infarction in Rats by Suppressing Myocardial Apoptosis and Endoplasmic Reticulum Stress.
Shi ZY, Liu Y, Dong L, Zhang B, Zhao M, Liu WX, Zhang X, Yin XH
Journal of cardiovascular pharmacology and therapeutics 2017 Jan;22(1):83-93
Journal of cardiovascular pharmacology and therapeutics 2017 Jan;22(1):83-93
Effects of visfatin on the apoptosis of intestinal mucosal cells in immunological stressed rats.
Zhou Y, Yuan HR, Cui L, Ansari AR, Xiao K, Luo Y, Wu XT, Guo L, Khan FA, Yang Z, Song H
Acta histochemica 2017 Jan;119(1):26-31
Acta histochemica 2017 Jan;119(1):26-31
Carboxyfullerene nanoparticles alleviate acute hepatic injury in severe hemorrhagic shock.
Chen G, Song X, Wang B, You G, Zhao J, Xia S, Zhang Y, Zhao L, Zhou H
Biomaterials 2017 Jan;112:72-81
Biomaterials 2017 Jan;112:72-81
Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells.
Dai X, Dong M, Yu H, Xie Y, Yu Y, Cao Y, Kong Z, Zhou B, Xu Y, Yang T, Li K
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 26;23:452-461
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 26;23:452-461
Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress, NF-κB inhibition and mitochondrial dysfunction.
Mehmood T, Maryam A, Zhang H, Li Y, Khan M, Ma T
BioFactors (Oxford, England) 2017 Jan 2;43(1):63-72
BioFactors (Oxford, England) 2017 Jan 2;43(1):63-72
Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression.
Zhao XS, Wu Q, Peng J, Pan LH, Ren Z, Liu HT, Jiang ZS, Wang GX, Tang ZH, Liu LS
Molecular medicine reports 2017 Feb;15(2):712-718
Molecular medicine reports 2017 Feb;15(2):712-718
Inhibition of store-operated Ca(2+) entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate.
Huang W, Ren C, Huang G, Liu J, Liu W, Wang L, Zhu B, Feng X, Shi J, Li J, Xia X, Jia W, Chen J, Chen Y, Jiang X
Oncology letters 2017 Feb;13(2):921-929
Oncology letters 2017 Feb;13(2):921-929
Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway.
Yan X, Yang W, Shao Z, Yang S, Liu X
Journal of biomedical materials research. Part A 2017 Feb;105(2):443-453
Journal of biomedical materials research. Part A 2017 Feb;105(2):443-453
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, Ma H, He K, Wang Y, Han B, Ye X, Li X
Scientific reports 2017 Feb 6;7:38524
Scientific reports 2017 Feb 6;7:38524
Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice.
Dong Q, Li J, Wu QF, Zhao N, Qian C, Ding D, Wang BB, Chen L, Guo KF, Fu D, Han B, Liao YH, Du YM
Scientific reports 2017 Feb 16;7:42678
Scientific reports 2017 Feb 16;7:42678
Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis.
Liu Y, Pu Y, Li D, Zhou L, Wan L
Life sciences 2017 Feb 1;170:1-8
Life sciences 2017 Feb 1;170:1-8
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, Qaed E, Lin Y, Peng J, Ma X, Zhang J, Wang S, Tang Z
Cell biology international 2017 Dec;41(12):1367-1378
Cell biology international 2017 Dec;41(12):1367-1378
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, Zhao Y, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Gao C, Zhou Y, Li H, Cong X, Jiang Z, Wang X, Cao R, Tian W
Molecular medicine reports 2017 Dec;16(6):8729-8734
Molecular medicine reports 2017 Dec;16(6):8729-8734
Abnormal expression levels of BMP15/Smad1 are associated with granulosa cell apoptosis in patients with polycystic ovary syndrome.
Cui X, Jing X, Wu X, Bi X, Liu J, Long Z, Zhang X, Zhang D, Jia H, Su D, Huo K
Molecular medicine reports 2017 Dec;16(6):8231-8236
Molecular medicine reports 2017 Dec;16(6):8231-8236
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Gu YP, Yang XM, Duan ZH, Luo P, Shang JH, Xiao W, Tao YX, Zhang DY, Zhang YB, Liu HZ
Experimental and therapeutic medicine 2017 Dec;14(6):5889-5895
Experimental and therapeutic medicine 2017 Dec;14(6):5889-5895
Regulation of macrophage migration in ischemic mouse hearts via an AKT2/NBA1/SPK1 pathway.
Yang Y, Zhao J, Zhang J, Lei Y, Yuan F, Liu L, Gao H, Guo H, Niu X, Chen R, Fu X, Han Y, Han H, Chan T, Zhao L, Wang H, Zheng Q, Li X
Oncotarget 2017 Dec 29;8(70):115345-115359
Oncotarget 2017 Dec 29;8(70):115345-115359
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, Kong F, Xu B, Li S, Yang H
Oncotarget 2017 Dec 29;8(70):115304-115314
Oncotarget 2017 Dec 29;8(70):115304-115314
Effect of Boron on Thymic Cytokine Expression, Hormone Secretion, Antioxidant Functions, Cell Proliferation, and Apoptosis Potential via the Extracellular Signal-Regulated Kinases 1 and 2 Signaling Pathway.
Jin E, Ren M, Liu W, Liang S, Hu Q, Gu Y, Li S
Journal of agricultural and food chemistry 2017 Dec 27;65(51):11280-11291
Journal of agricultural and food chemistry 2017 Dec 27;65(51):11280-11291
miR-19a protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis via PTEN/PI3K/p-Akt pathway.
Sun G, Lu Y, Li Y, Mao J, Zhang J, Jin Y, Li Y, Sun Y, Liu L, Li L
Bioscience reports 2017 Dec 22;37(6)
Bioscience reports 2017 Dec 22;37(6)
Boron Affects Immune Function Through Modulation of Splenic T Lymphocyte Subsets, Cytokine Secretion, and Lymphocyte Proliferation and Apoptosis in Rats.
Jin E, Li S, Ren M, Hu Q, Gu Y, Li K
Biological trace element research 2017 Aug;178(2):261-275
Biological trace element research 2017 Aug;178(2):261-275
Treatment mechanism of matrine in combination with irinotecan for colon cancer.
Duan L, Deng L, Wang D, Ma S, Li C, Zhao D
Oncology letters 2017 Aug;14(2):2300-2304
Oncology letters 2017 Aug;14(2):2300-2304
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Tang H, Yao X, Yao C, Zhao X, Zuo H, Li Z
Scientific reports 2017 Aug 8;7(1):7599
Scientific reports 2017 Aug 8;7(1):7599
Establishment of an ideal time window model in hypothermic-targeted temperature management after traumatic brain injury in rats.
Zhao WY, Chen SB, Wang JJ, Xu C, Zhao ML, Dong HJ, Liang HQ, Li XH, Tu Y, Zhang S, Chen C, Sun HT
Brain research 2017 Aug 15;1669:141-149
Brain research 2017 Aug 15;1669:141-149
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, Sun B, Song Y, Lin Y, Peng J, Tang Z
Vascular pharmacology 2017 Apr;91:26-35
Vascular pharmacology 2017 Apr;91:26-35
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
Wang CP, Shi YW, Tang M, Zhang XC, Gu Y, Liang XM, Wang ZW, Ding F
Molecular neurobiology 2017 Apr;54(3):2126-2142
Molecular neurobiology 2017 Apr;54(3):2126-2142
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
Wang H, Xu YS, Wang ML, Cheng C, Bian R, Yuan H, Wang Y, Guo T, Zhu LL, Zhou H
International journal of molecular medicine 2017 Apr;39(4):819-830
International journal of molecular medicine 2017 Apr;39(4):819-830
Long-term effects of repeated superovulation on the uterus and mammary gland in rhesus monkeys.
Yan P, Xu J, Zeng Y, Dong G, Cao H, Zheng M, Zhu H
Journal of assisted reproduction and genetics 2017 Apr;34(4):535-545
Journal of assisted reproduction and genetics 2017 Apr;34(4):535-545
MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3.
Zou M, Wang F, Jiang A, Xia A, Kong S, Gong C, Zhu M, Zhou X, Zhu J, Zhu W, Cheng W
Helicobacter 2017 Apr;22(2)
Helicobacter 2017 Apr;22(2)
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Yao C, Cao X, Fu Z, Tian J, Dong W, Xu J, An K, Zhai L, Yu J
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 29;23:2059-2064
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 29;23:2059-2064
Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa.
Ma H, Li L, Dou G, Wang C, Li J, He H, Wu M, Qi H
Oncotarget 2017 Apr 25;8(17):29328-29345
Oncotarget 2017 Apr 25;8(17):29328-29345
Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats.
Feng D, Yao J, Wang G, Li Z, Zu G, Li Y, Luo F, Ning S, Qasim W, Chen Z, Tian X
Clinical science (London, England : 1979) 2017 Apr 25;131(8):759-773
Clinical science (London, England : 1979) 2017 Apr 25;131(8):759-773
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
Chronic Sleep Deprivation Exacerbates Learning-Memory Disability and Alzheimer's Disease-Like Pathologies in AβPP(swe)/PS1(ΔE9) Mice.
Qiu H, Zhong R, Liu H, Zhang F, Li S, Le W
Journal of Alzheimer's disease : JAD 2016;50(3):669-85
Journal of Alzheimer's disease : JAD 2016;50(3):669-85
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin.
Zeng J, Song F, Yang Y, Ma C, Deng G, Li Y, Wang Y, Liu X
Journal of immunology research 2016;2016:5708468
Journal of immunology research 2016;2016:5708468
Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway.
Yang J, Zhang K, Wu J, Shi J, Xue J, Li J, Chen J, Zhu Y, Wei J, He J, Liu X
Stem cells international 2016;2016:1690896
Stem cells international 2016;2016:1690896
OFD1, as a Ciliary Protein, Exhibits Neuroprotective Function in Photoreceptor Degeneration Models.
Wang J, Chen X, Wang F, Zhang J, Li P, Li Z, Xu J, Gao F, Jin C, Tian H, Zhang J, Li W, Lu L, Xu GT
PloS one 2016;11(5):e0155860
PloS one 2016;11(5):e0155860
Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.
Li J, Chen K, Li S, Liu T, Wang F, Xia Y, Lu J, Zhou Y, Guo C
PloS one 2016;11(4):e0152570
PloS one 2016;11(4):e0152570
Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet.
Sun Q, Nie S, Wang L, Yang F, Meng Z, Xiao H, Xiang B, Li X, Fu X, Wang S
PloS one 2016;11(3):e0151104
PloS one 2016;11(3):e0151104
SIRT2 Plays Significant Roles in Lipopolysaccharides-Induced Neuroinflammation and Brain Injury in Mice.
Wang B, Zhang Y, Cao W, Wei X, Chen J, Ying W
Neurochemical research 2016 Sep;41(9):2490-500
Neurochemical research 2016 Sep;41(9):2490-500
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Wang Y, Zhang XN, Xie WH, Zheng YX, Cao JP, Cao PR, Chen QJ, Li X, Sun CD
Nutrients 2016 Sep 27;8(10)
Nutrients 2016 Sep 27;8(10)
Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway.
Li Y, Jiang Z, Xue D, Deng G, Li M, Liu X, Wang Y
BMC microbiology 2016 Sep 23;16(1):222
BMC microbiology 2016 Sep 23;16(1):222
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Dia VP, Krishnan HB
Scientific reports 2016 Sep 15;6:33532
Scientific reports 2016 Sep 15;6:33532
Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis.
Zhang Y, Cheng Z, Wang C, Ma H, Meng W, Zhao Q
Neurochemical research 2016 Oct;41(10):2549-2558
Neurochemical research 2016 Oct;41(10):2549-2558
Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway.
Tang D, Wang C, Gao Y, Pu J, Long J, Xu W
Neuroscience letters 2016 Oct 6;632:79-85
Neuroscience letters 2016 Oct 6;632:79-85
Knockdown of Myosin 6 inhibits proliferation of oral squamous cell carcinoma cells.
Zhang X, Huang Z, Hu Y, Liu L
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016 Nov;45(10):740-745
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016 Nov;45(10):740-745
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, Zhang Z, Lin Y, Peng J, Song Z, Wang S, Tang Z
International immunopharmacology 2016 Nov;40:400-409
International immunopharmacology 2016 Nov;40:400-409
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis.
Song Z, Chen CP, Liu J, Wen X, Sun H, Yuan H
European journal of medicinal chemistry 2016 Nov 29;124:809-819
European journal of medicinal chemistry 2016 Nov 29;124:809-819
Multifunctional Gold Nanoclusters-Based Nanosurface Energy Transfer Probe for Real-Time Monitoring of Cell Apoptosis and Self-Evaluating of Pro-Apoptotic Theranostics.
Li Y, Li P, Zhu R, Luo C, Li H, Hu S, Nie Z, Huang Y, Yao S
Analytical chemistry 2016 Nov 15;88(22):11184-11192
Analytical chemistry 2016 Nov 15;88(22):11184-11192
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, Sun H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
Geng J, Fan FL, He S, Liu Y, Meng Y, Tian H, Zhang D, Ma Q, Zhang JB, Tian HY
Experimental lung research 2016 May;42(4):190-8
Experimental lung research 2016 May;42(4):190-8
Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.
Öz A, Çelik Ö
Molecular membrane biology 2016 May-Aug;33(3-5):76-88
Molecular membrane biology 2016 May-Aug;33(3-5):76-88
Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack.
Feng G, Li J, Zheng M, Yang Z, Liu Y, Zhang S, Ye L, Zhang W, Zhang X
Oncotarget 2016 May 10;7(19):28013-26
Oncotarget 2016 May 10;7(19):28013-26
β-Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-κB Signaling Pathway.
Zhu X, Zhang Y, Li Q, Yang L, Zhang N, Ma S, Zhang K, Song J, Guan F
Journal of biochemical and molecular toxicology 2016 Mar;30(3):148-57
Journal of biochemical and molecular toxicology 2016 Mar;30(3):148-57
Phosphocreatine protects against LPS-induced human umbilical vein endothelial cell apoptosis by regulating mitochondrial oxidative phosphorylation.
Sun Z, Lan X, Ahsan A, Xi Y, Liu S, Zhang Z, Chu P, Song Y, Piao F, Peng J, Lin Y, Han G, Tang Z
Apoptosis : an international journal on programmed cell death 2016 Mar;21(3):283-97
Apoptosis : an international journal on programmed cell death 2016 Mar;21(3):283-97
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
Yu Y, Xu X, Liu L, Mao S, Feng T, Lu Y, Cheng Y, Wang H, Zhao W, Tang W
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Huang M, Xu A, Wu X, Zhang Y, Guo Y, Guo F, Pan Z, Kong L
Archives of virology 2016 Mar;161(3):699-703
Archives of virology 2016 Mar;161(3):699-703
Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress.
Wang Z, Du T, Dong X, Li Z, Wu G, Zhang R
International journal of oncology 2016 Jun;48(6):2558-66
International journal of oncology 2016 Jun;48(6):2558-66
Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.
Zhao X, Tao X, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Molecules (Basel, Switzerland) 2016 Jun 4;21(6)
Molecules (Basel, Switzerland) 2016 Jun 4;21(6)
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Zou M, Duan Y, Wang P, Gao R, Chen X, Ou Y, Liang M, Wang Z, Yuan Y, Wang L, Zhu H
Scientific reports 2016 Jun 2;6:27331
Scientific reports 2016 Jun 2;6:27331
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Zhang W, Yin L, Tao X, Xu L, Zheng L, Han X, Xu Y, Wang C, Peng J
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Environmental toxicology and pharmacology 2016 Jul;45:193-201
GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia.
Lu J, Zhang Q, Tan D, Luo W, Zhao H, Ma J, Liang H, Tan Y
International journal of molecular medicine 2016 Jul;38(1):105-12
International journal of molecular medicine 2016 Jul;38(1):105-12
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.
Zhao Y, Jing Z, Li Y, Mao W
Oncology reports 2016 Jul;36(1):567-72
Oncology reports 2016 Jul;36(1):567-72
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma.
Zhang XF, Pan QZ, Pan K, Weng DS, Wang QJ, Zhao JJ, He J, Liu Q, Wang DD, Jiang SS, Zheng HX, Lv L, Chen CL, Zhang HX, Xia JC
Molecular carcinogenesis 2016 Jan;55(1):64-76
Molecular carcinogenesis 2016 Jan;55(1):64-76
Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells.
Zhao C, Su G, Wang X, Zhang X, Guo S, Zhao Y
Biotechnology letters 2016 Jan;38(1):43-50
Biotechnology letters 2016 Jan;38(1):43-50
Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells.
Peng X, Zhang YY, Wang J, Ji Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):865-76
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):865-76
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, Hang H, Liu S, Chu P, Sun Z, Sun B, Lin Y, Peng J, Han G, Wang S, Tang Z
Chemico-biological interactions 2016 Jan 25;244:94-104
Chemico-biological interactions 2016 Jan 25;244:94-104
Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.
Cui XB, Li S, Li TT, Peng H, Jin TT, Zhang SM, Liu CX, Yang L, Shen YY, Li SG, Li N, Li Y, Hu JM, Jiang JF, Suo J, Qi Y, Liang WH, Wang LH, Dang HW, Li L, Cao WW, Wei Y, Laibo-Yin, Wu CY, Yuan XL, Zhou H, Zheng Y, Chen YZ, Li F
Oncotarget 2016 Jan 12;7(2):1777-95
Oncotarget 2016 Jan 12;7(2):1777-95
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, Shi D
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.
Zhao M, Fan J, Liu Y, Yu Y, Xu J, Wen Q, Zhang J, Fu S, Wang B, Xiang L, Feng J, Wu J, Yang L
International journal of oncology 2016 Feb;48(2):756-64
International journal of oncology 2016 Feb;48(2):756-64
Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.
Gao L, Xu Z, Wang Y, Sun B, Song Z, Yang B, Liu X, Lin Y, Peng J, Han G, Wang S, Tang Z
Oncology reports 2016 Feb;35(2):1101-8
Oncology reports 2016 Feb;35(2):1101-8
Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice.
Wang X, Tian J, Yong KT, Zhu X, Lin MC, Jiang W, Li J, Huang Q, Lin G
Journal of nanobiotechnology 2016 Feb 4;14:10
Journal of nanobiotechnology 2016 Feb 4;14:10
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
Li X, He Y, Xu Y, Huang X, Liu J, Xie M, Liu X
American journal of physiology. Lung cellular and molecular physiology 2016 Feb 15;310(4):L299-310
American journal of physiology. Lung cellular and molecular physiology 2016 Feb 15;310(4):L299-310
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Zhao L, Wen Q, Yang G, Huang Z, Shen T, Li H, Ren D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Feb 15;23(2):114-22
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Feb 15;23(2):114-22
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Mao Y, Wang J, Yu F, Li Z, Li H, Guo C, Fan X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:305-313
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:305-313
Corilagin Attenuates Radiation-Induced Brain Injury in Mice.
Tong F, Zhang J, Liu L, Gao X, Cai Q, Wei C, Dong J, Hu Y, Wu G, Dong X
Molecular neurobiology 2016 Dec;53(10):6982-6996
Molecular neurobiology 2016 Dec;53(10):6982-6996
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, Zhang J, Liu L, Li W
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Journal of ethnopharmacology 2016 Dec 4;193:368-376
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, Cong W, Cheng J, Yang W, Sun W, Cui S
Oncotarget 2016 Dec 20;7(51):84839-84850
Oncotarget 2016 Dec 20;7(51):84839-84850
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Tang Q, Ji F, Sun W, Wang J, Guo J, Guo L, Li Y, Bao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Dec 15;23(14):1778-1786
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Dec 15;23(14):1778-1786
Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin.
Tang Q, Ji F, Guo J, Wang J, Li Y, Bao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Aug;82:693-703
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Aug;82:693-703
Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy.
Wan X, Pu H, Huang W, Yang S, Zhang Y, Kong Z, Yang Z, Zhao P, Li A, Li T, Li Y
Oncotarget 2016 Aug 9;7(32):51284-51300
Oncotarget 2016 Aug 9;7(32):51284-51300
HspB8 mediates neuroprotection against OGD/R in N2A cells through the phosphoinositide 3-kinase/Akt pathway.
Hu Z, Yang B, Mo X, Zhou F
Brain research 2016 Aug 1;1644:15-21
Brain research 2016 Aug 1;1644:15-21
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
Xia ZX, Li ZX, Zhang M, Sun LM, Zhang QF, Qiu XS
Experimental and molecular pathology 2016 Apr;100(2):353-60
Experimental and molecular pathology 2016 Apr;100(2):353-60
Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice.
Mao Y, Wang J, Yu F, Cheng J, Li H, Guo C, Fan X
Drug design, development and therapy 2015;9:5385-96
Drug design, development and therapy 2015;9:5385-96
MiR-124 effect in neurons apoptosis in newborn rat with thyroid hypofunction.
Shao Q, Jiang W, Jin Y
International journal of clinical and experimental pathology 2015;8(11):14465-71
International journal of clinical and experimental pathology 2015;8(11):14465-71
Level of circulated microRNA-421 in gastric carcinoma and related mechanisms.
Zhao G, Xu L, Hui L, Zhao J
International journal of clinical and experimental pathology 2015;8(11):14252-6
International journal of clinical and experimental pathology 2015;8(11):14252-6
Effects of the total saponins from Dioscorea nipponica on immunoregulation in aplastic anemia mice.
Wang Y, Yan T, Ma L, Liu B
The American journal of Chinese medicine 2015;43(2):289-303
The American journal of Chinese medicine 2015;43(2):289-303
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Zhang C, Zhang J, Li X, Sun N, Yu R, Zhao B, Yu D, Cheng Y, Liu Y
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
Gu A, Jie Y, Sun L, Zhao S, E M, You Q
PloS one 2015;10(9):e0137337
PloS one 2015;10(9):e0137337
A comparison of the biological effects of 125I seeds continuous low-dose-rate radiation and 60Co high-dose-rate gamma radiation on non-small cell lung cancer cells.
Wang Z, Zhao Z, Lu J, Chen Z, Mao A, Teng G, Liu F
PloS one 2015;10(8):e0133728
PloS one 2015;10(8):e0133728
Decreased expression of RPS15A suppresses proliferation of lung cancer cells.
Zhao X, Shen L, Feng Y, Yu H, Wu X, Chang J, Shen X, Qiao J, Wang J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6733-40
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6733-40
Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice.
Zhao P, Zhou R, Zhu XY, Hao YJ, Li N, Wang J, Niu Y, Sun T, Li YX, Yu JQ
International journal of molecular medicine 2015 Sep;36(3):633-44
International journal of molecular medicine 2015 Sep;36(3):633-44
Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.
Fu C, Xu D, Wang CY, Jin Y, Liu Q, Meng Q, Liu KX, Sun HJ, Liu MZ
Journal of cellular physiology 2015 Sep;230(9):2184-201
Journal of cellular physiology 2015 Sep;230(9):2184-201
Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus.
Wei P, Liu Q, Li D, Zheng Q, Zhou J, Li J
Neuroscience letters 2015 Sep 14;604:161-6
Neuroscience letters 2015 Sep 14;604:161-6
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Ma Z, Hou T, Shi W, Liu W, He H
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
Oxymatrine attenuated hypoxic-ischemic brain damage in neonatal rats via improving antioxidant enzyme activities and inhibiting cell death.
Zhao P, Zhou R, Li HN, Yao WX, Qiao HQ, Wang SJ, Niu Y, Sun T, Li YX, Yu JQ
Neurochemistry international 2015 Oct;89:17-27
Neurochemistry international 2015 Oct;89:17-27
Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.
Zhang HT, Xue JH, Zhang ZW, Kong HB, Liu AJ, Li SC, Xu DG
Brain research 2015 Oct 5;1622:474-83
Brain research 2015 Oct 5;1622:474-83
XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy.
Qin CJ, Song XM, Chen ZH, Ren XQ, Xu KW, Jing H, He YL
Oncotarget 2015 Oct 13;6(31):32193-204
Oncotarget 2015 Oct 13;6(31):32193-204
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Liang ZE, Yi YJ, Guo YT, Wang RC, Hu QL, Xiong XY
Molecular medicine reports 2015 Nov;12(5):7629-36
Molecular medicine reports 2015 Nov;12(5):7629-36
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Song X, Li L, Shi Q, Lehmler HJ, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Nov 16;28(11):2160-9
Chemical research in toxicology 2015 Nov 16;28(11):2160-9
RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker.
Jin Y, Cao B, Zhang M, Zhan Q, Herman JG, Yu M, Guo M
Genes & cancer 2015 May;6(5-6):231-40
Genes & cancer 2015 May;6(5-6):231-40
An ESRG-interacting protein, COXII, is involved in pro-apoptosis of human embryonic stem cells.
Shi J, Ren C, Liu H, Wang L, Zhu B, Huang W, Liu W, Liu J, Liu Y, Xia X, Xu R, Jiang X
Biochemical and biophysical research communications 2015 May 1;460(2):130-5
Biochemical and biophysical research communications 2015 May 1;460(2):130-5
Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells.
Li X, Zou K, Gou J, Du Q, Li D, He X, Li Z
Medical oncology (Northwood, London, England) 2015 Mar;32(3):72
Medical oncology (Northwood, London, England) 2015 Mar;32(3):72
MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer.
Yang T, Thakur A, Chen T, Yang L, Lei G, Liang Y, Zhang S, Ren H, Chen M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Jun;36(6):4357-65
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Jun;36(6):4357-65
MiR-17-5p up-regulates YES1 to modulate the cell cycle progression and apoptosis in ovarian cancer cell lines.
Li L, He L, Zhao JL, Xiao J, Liu M, Li X, Tang H
Journal of cellular biochemistry 2015 Jun;116(6):1050-9
Journal of cellular biochemistry 2015 Jun;116(6):1050-9
Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.
Lei ZJ, Wang J, Xiao HL, Guo Y, Wang T, Li Q, Liu L, Luo X, Fan LL, Lin L, Mao CY, Wang SN, Wei YL, Lan CH, Jiang J, Yang XJ, Liu PD, Chen DF, Wang B
Oncogene 2015 Jun 11;34(24):3188-98
Oncogene 2015 Jun 11;34(24):3188-98
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Hu L, Su C, Song X, Shi Q, Fu J, Xia X, Xu D, Song E, Song Y
Neurotoxicology 2015 Jul;49:149-57
Neurotoxicology 2015 Jul;49:149-57
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.
Zhang Y, Li R, Zhu J, Wang Z, Lv S, Xiong JY
The Journal of surgical research 2015 Jan;193(1):399-406
The Journal of surgical research 2015 Jan;193(1):399-406
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Lu T, Yang W, Wang Z, Hu Z, Zeng X, Yang C, Wang Y, Zhang Y, Li F, Liu Z, Wang D, Ye Z
Molecular medicine reports 2015 Jan;11(1):249-56
Molecular medicine reports 2015 Jan;11(1):249-56
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Yuan X, Du J, Hua S, Zhang H, Gu C, Wang J, Yang L, Huang J, Yu J, Liu F
Experimental cell research 2015 Jan 15;330(2):267-276
Experimental cell research 2015 Jan 15;330(2):267-276
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
Li X, Liu X, Xu Y, He Y, Liu J, Xie M
International journal of oncology 2015 Feb;46(2):677-84
International journal of oncology 2015 Feb;46(2):677-84
KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma.
Guo Z, Liu J, Zhang L, Su B, Xing Y, He Q, Ci W, Li X, Zhou L
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Feb;36(2):1251-9
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Feb;36(2):1251-9
The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats.
Xiao K, Zou WH, Yang Z, Rehman ZU, Ansari AR, Yuan HR, Zhou Y, Cui L, Peng KM, Song H
Cell and tissue research 2015 Feb;359(2):605-618
Cell and tissue research 2015 Feb;359(2):605-618
Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice.
Zhang XY, Cao JB, Zhang LM, Li YF, Mi WD
Journal of neuroinflammation 2015 Feb 3;12:20
Journal of neuroinflammation 2015 Feb 3;12:20
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.
Gao L, Wang Y, Xu Z, Li X, Wu J, Liu S, Chu P, Sun Z, Sun B, Lin Y, Peng J, Han G, Wang S, Tang Z
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1636-50
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1636-50
Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway.
Ahsan A, Han G, Pan J, Liu S, Padhiar AA, Chu P, Sun Z, Zhang Z, Sun B, Wu J, Irshad A, Lin Y, Peng J, Tang Z
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1563-76
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1563-76
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.
Shan X, Tian LL, Zhang YM, Wang XQ, Yan Q, Liu JW
International journal of oncology 2015 Aug;47(2):701-9
International journal of oncology 2015 Aug;47(2):701-9
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
Yuan L, Zhou C, Lu Y, Hong M, Zhang Z, Zhang Z, Chang Y, Zhang C, Li X
Cancer letters 2015 Apr 1;359(1):136-47
Cancer letters 2015 Apr 1;359(1):136-47
Traumatic brain injury dysregulates microRNAs to modulate cell signaling in rat hippocampus.
Liu L, Sun T, Liu Z, Chen X, Zhao L, Qu G, Li Q
PloS one 2014;9(8):e103948
PloS one 2014;9(8):e103948
Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice.
Wang T, Li Y, Wang Y, Zhou R, Ma L, Hao Y, Jin S, Du J, Zhao C, Sun T, Yu J
PloS one 2014;9(3):e90780
PloS one 2014;9(3):e90780
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
Zhao L, Teng B, Wen L, Feng Q, Wang H, Li N, Wang Y, Liang Z
International journal of clinical and experimental medicine 2014;7(2):337-47
International journal of clinical and experimental medicine 2014;7(2):337-47
14-Thienyl methylene matrine (YYJ18), the derivative from matrine, induces apoptosis of human nasopharyngeal carcinoma cells by targeting MAPK and PI3K/Akt pathways in vitro.
Xie M, Yi X, Wang R, Wang L, He G, Zhu M, Qi C, Liu Y, Ye Y, Tan S, Tang A
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;33(5):1475-83
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;33(5):1475-83
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Li W, Wang C, Peng J, Liang J, Jin Y, Liu Q, Meng Q, Liu K, Sun H
Current pharmaceutical biotechnology 2014;15(12):1173-82
Current pharmaceutical biotechnology 2014;15(12):1173-82
Gastrodin prevents steroid-induced osteonecrosis of the femoral head in rats by anti-apoptosis.
Zheng H, Yang E, Peng H, Li J, Chen S, Zhou J, Fang H, Qiu B, Wang Z
Chinese medical journal 2014;127(22):3926-31
Chinese medical journal 2014;127(22):3926-31
Inhibition of autophagy enhances the anticancer activity of silver nanoparticles.
Lin J, Huang Z, Wu H, Zhou W, Jin P, Wei P, Zhang Y, Zheng F, Zhang J, Xu J, Hu Y, Wang Y, Li Y, Gu N, Wen L
Autophagy 2014;10(11):2006-20
Autophagy 2014;10(11):2006-20
Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons.
Wang CP, Li GC, Shi YW, Zhang XC, Li JL, Wang ZW, Ding F, Liang XM
Journal of physiology and biochemistry 2014 Sep;70(3):735-47
Journal of physiology and biochemistry 2014 Sep;70(3):735-47
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Tao X, Wan X, Xu Y, Xu L, Qi Y, Yin L, Han X, Lin Y, Peng J
Transplantation 2014 Sep 27;98(6):604-11
Transplantation 2014 Sep 27;98(6):604-11
KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α.
Li X, Liu X, Xu Y, Liu J, Xie M, Ni W, Chen S
International journal of oncology 2014 Oct;45(4):1507-14
International journal of oncology 2014 Oct;45(4):1507-14
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
Kuang J, Wang YL, Xiao M, Tang Y, Chen WW, Song GL, Yang X, Li M
Oncology reports 2014 May;31(5):2335-43
Oncology reports 2014 May;31(5):2335-43
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X
International journal of molecular sciences 2014 May 22;15(5):9103-16
International journal of molecular sciences 2014 May 22;15(5):9103-16
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
Matrine-induced apoptosis of human nasopharyngeal carcinoma cells via in vitro vascular endothelial growth factor-A/extracellular signal-regulated kinase1/2 pathway inactivation.
Xie M, He G, Wang R, Shi S, Chen J, Ye Y, Xie L, Yi X, Tang A
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2014 Jul;46(8):556-60
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2014 Jul;46(8):556-60
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Li M, Lu Y, Hu Y, Zhai X, Xu W, Jing H, Tian X, Lin Y, Gao D, Yao J
Toxicology letters 2014 Jul 15;228(2):67-74
Toxicology letters 2014 Jul 15;228(2):67-74
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Sun Q, Wang R, Wang Y, Luo J, Wang P, Cheng B
Oncology reports 2014 Feb;31(2):933-9
Oncology reports 2014 Feb;31(2):933-9
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
Liang JX, Ning Z, Gao W, Ling J, Wang AM, Luo HF, Liang Y, Yan Q, Wang ZY
Oncology reports 2014 Dec;32(6):2726-34
Oncology reports 2014 Dec;32(6):2726-34
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Yu H, Zheng L, Yin L, Xu L, Qi Y, Han X, Xu Y, Liu K, Peng J
International immunopharmacology 2014 Apr;19(2):233-44
International immunopharmacology 2014 Apr;19(2):233-44
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Hu L, Li L, Xu D, Xia X, Pi R, Xu D, Wang W, Du H, Song E, Song Y
Chemico-biological interactions 2014 Apr 25;213:51-9
Chemico-biological interactions 2014 Apr 25;213:51-9
The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice.
An J, Zhang X, Qin J, Wan Y, Hu Y, Liu T, Li J, Dong W, Du E, Pan C, Zeng W
Cell death & disease 2014 Apr 24;5(4):e1196
Cell death & disease 2014 Apr 24;5(4):e1196
Oxysophoridine protects against focal cerebral ischemic injury by inhibiting oxidative stress and apoptosis in mice.
Wang TF, Lei Z, Li YX, Wang YS, Wang J, Wang SJ, Hao YJ, Zhou R, Jin SJ, Du J, Li J, Sun T, Yu JQ
Neurochemical research 2013 Nov;38(11):2408-17
Neurochemical research 2013 Nov;38(11):2408-17
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Zhang S, Lu B, Han X, Xu L, Qi Y, Yin L, Xu Y, Zhao Y, Liu K, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis.
Wei DH, Jia XY, Liu YH, Guo FX, Tang ZH, Li XH, Wang Z, Liu LS, Wang GX, Jian ZS, Ruan CG
International journal of molecular medicine 2013 Feb;31(2):400-6
International journal of molecular medicine 2013 Feb;31(2):400-6
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Wang CP, Li JL, Zhang LZ, Zhang XC, Yu S, Liang XM, Ding F, Wang ZW
Neurochemistry international 2013 Dec;63(8):741-9
Neurochemistry international 2013 Dec;63(8):741-9
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Dong D, Zhang S, Yin L, Tang X, Xu Y, Han X, Qi Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Tu JB, Ma RZ, Dong Q, Jiang F, Hu XY, Li QY, Pattar P, Zhang H
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Total flavonoids from Rosa Laevigata Michx fruit attenuates hydrogen peroxide induced injury in human umbilical vein endothelial cells.
Jia Y, Ji L, Zhang S, Xu L, Yin L, Li L, Zhao Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Sep;50(9):3133-41
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Sep;50(9):3133-41
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 19677-1-AP(CASP3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 19677-1-AP(CASP3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Caspase 3 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Caspase 3. This antibody recognizes human,mouse,rat antigen. The Caspase 3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
