BS6428

antibody from Bioworld Technology, Inc
Targeting: CASP3 apopain, CPP32, CPP32B, Yama
Provider product page for BS6428
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6428 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Caspase 3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Caspase 3.
Description
Caspase 3 (also known as CPP32, YAMA and apopain) is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10).The processed form of Caspase 3 consists of large (17kD) and small (12kD) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 - Ser29 and Asp175 - Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CASP3 protein structure - BS6428 shown in red.