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- References [10]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- GTX86952 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX86952, RRID:AB_10722506
- Product name
- Caspase 3 (cleaved Asp175) antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references Effect of mild hypothermia on cerebral microcirculation in a murine cardiopulmonary resuscitation model.
Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair.
Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair.
Beta-mangostin from Cratoxylum arborescens activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest.
Tanshinone IIA induces intrinsic apoptosis in osteosarcoma cells both in vivo and in vitro associated with mitochondrial dysfunction.
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
Phyllanthus urinaria's Inhibition of Human Osteosarcoma Xenografts Growth in Mice is Associated with Modulation of Mitochondrial Fission/Fusion Machinery.
Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy.
PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage.
Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2H-benzo[h]chromen-2-one and 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogues with improved water solubility.
Yu H, Wang L, Zhang H, Wei W, Chen Y, Tang W, Wan Z
Microcirculation (New York, N.Y. : 1994) 2019 Feb 23;
Microcirculation (New York, N.Y. : 1994) 2019 Feb 23;
Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair.
Chen CC, Chen CY, Wang SH, Yeh CT, Su SC, Ueng SH, Chuang WY, Hsueh C, Wang TH
Cancers 2018 Sep 10;10(9)
Cancers 2018 Sep 10;10(9)
Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair.
Chen CC, Chen CY, Ueng SH, Hsueh C, Yeh CT, Ho JY, Chou LF, Wang TH
Cell death & disease 2018 May 1;9(5):543
Cell death & disease 2018 May 1;9(5):543
Beta-mangostin from Cratoxylum arborescens activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest.
Omer FAA, Hashim NBM, Ibrahim MY, Dehghan F, Yahayu M, Karimian H, Salim LZA, Mohan S
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Nov;39(11):1010428317731451
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Nov;39(11):1010428317731451
Tanshinone IIA induces intrinsic apoptosis in osteosarcoma cells both in vivo and in vitro associated with mitochondrial dysfunction.
Huang ST, Huang CC, Huang WL, Lin TK, Liao PL, Wang PW, Liou CW, Chuang JH
Scientific reports 2017 Jan 20;7:40382
Scientific reports 2017 Jan 20;7:40382
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
He Y, Pan S, Xu M, He R, Huang W, Song P, Huang J, Zhang HT, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392
Phyllanthus urinaria's Inhibition of Human Osteosarcoma Xenografts Growth in Mice is Associated with Modulation of Mitochondrial Fission/Fusion Machinery.
Huang ST, Huang CC, Sheen JM, Lin TK, Liao PL, Huang WL, Wang PW, Liou CW, Chuang JH
The American journal of Chinese medicine 2016;44(7):1507-1523
The American journal of Chinese medicine 2016;44(7):1507-1523
Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy.
Zheng Y, Yin G, Le V, Zhang A, Chen S, Liang X, Liu J
International journal of biological sciences 2016;12(1):120-32
International journal of biological sciences 2016;12(1):120-32
PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage.
Qu J, Lu D, Guo H, Miao W, Wu G, Zhou M
Clinical and experimental pharmacology & physiology 2016 Mar;43(3):312-8
Clinical and experimental pharmacology & physiology 2016 Mar;43(3):312-8
Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2H-benzo[h]chromen-2-one and 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogues with improved water solubility.
Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Kim Y, Lee EY, Lee KH
Journal of natural products 2012 Mar 23;75(3):370-7
Journal of natural products 2012 Mar 23;75(3):370-7
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from 293 cells, treated with Etoposide 25uM 60', using Caspase 3 (Cleaved-Asp175) Antibody.(GTX86952) The lane on the right is treated with the synthesized peptide.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 3 (Cleaved-Asp175) antibody (GTX86952). The picture on the right is treated with the synthesized peptide.
