MAB2360

antibody from Abnova Corporation

Targeting: CASP3 apopain, CPP32, CPP32B, Yama

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

MAB2360

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB2360, RRID:AB_10547570

Product name

CASP3 monoclonal antibody, clone CPP32 4-1-18

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against full length recombinant CASP3.

Isotype

IgG

Antibody clone number

CPP32 4-1-18

Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.

Nikiforov MA, Riblett M, Tang WH, Gratchouck V, Zhuang D, Fernandez Y, Verhaegen M, Varambally S, Chinnaiyan AM, Jakubowiak AJ, Soengas MS
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 4;104(49):19488-93

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Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c.

Kirsch DG, Doseff A, Chau BN, Lim DS, de Souza-Pinto NC, Hansford R, Kastan MB, Lazebnik YA, Hardwick JM
The Journal of biological chemistry 1999 Jul 23;274(30):21155-61

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Oncogene-dependent apoptosis is mediated by caspase-9.

Fearnhead HO, Rodriguez J, Govek EE, Guo W, Kobayashi R, Hannon G, Lazebnik YA
Proceedings of the National Academy of Sciences of the United States of America 1998 Nov 10;95(23):13664-9

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of CASP3 from HEK293 cell extract using CASP3 monoclonal antibody, clone CPP32 4-1-18 (Cat # MAB2360). Lanes 1 and 2 contain inactive and active CASP3, respectively.