Antibody data
- Antibody Data
- Antigen structure
- References [36]
- Comments [0]
- Validations [0]
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- Product number
- M00334-2 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for CASPASE 3/CASP3 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat CASPASE 3/CASP3 information: Molecular Weight: 31608 MW; Subcellular Localization: Cytoplasm; Tissue Specificity: Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- GEA-3
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Baicalin-2-ethoxyethyl ester alleviates gentamicin-induced acute kidney injury via NF-κB signaling pathway.
Effects of alendronate on cartilage lesions and micro-architecture deterioration of subchondral bone in patellofemoral osteoarthritic ovariectomized rats with patella-baja.
SHARPIN contributes to sevoflurane-induced neonatal neurotoxicity through up-regulating HMGB1 to repress M2 like-macrophage polarization.
Cytisine-N-methylene-(5,7,4(')-trihydroxy)- isoflavone ameliorates ischemic stroke-induced brain injury in mouse by regulating the oxidative stress and BDNF-Trkb/Akt pathway.
Borneol-Modified Schisandrin B Micelles Cross the Blood-Brain Barrier To Treat Alzheimer's Disease in Aged Mice.
Hepatitis E virus causes apoptosis of ovarian cells in hens and resulting in a decrease in egg production.
A breakthrough in periodontitis treatment: Revealing the pharmacodynamic substances and mechanisms of Kouqiangjie formula.
Mitochondrial Fission in Nickel Nanoparticle-Induced Reproductive Toxicity: An In Vitro GC-1 Cell Study.
(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells.
Hsa_circ_0001550 impairs decidualization by regulating the proliferation and apoptosis of endometrial stromal cells.
Canagliflozin ameliorates high glucose-induced apoptosis in NRK-52E cells via inhibiting oxidative stress and activating AMPK/mTOR-mediated autophagy.
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
Aconitine induces cell apoptosis via mitochondria and death receptor signaling pathways in hippocampus cell line.
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Preparation of Nereid oligopeptide and investigation of the mechanism underlying the induction of apoptosis in human lung cancer H1299 cells.
Circular RNA Rbms1 inhibited the development of myocardial ischemia reperfusion injury by regulating miR-92a/BCL2L11 signaling pathway.
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Tanshinone IIA inhibits cardiomyocyte apoptosis and rescues cardiac function during doxorubicin-induced cardiotoxicity by activating the DAXX/MEK/ERK1/2 pathway.
Overexpression of miR-125a-5p Inhibits Hepatocyte Proliferation through the STAT3 Regulation In Vivo and In Vitro.
Emodin Ameliorates Renal Damage and Podocyte Injury in a Rat Model of Diabetic Nephropathy via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway.
Highly Tumor-Specific and Long-Acting Iodine-131 Microbeads for Enhanced Treatment of Hepatocellular Carcinoma with Low-Dose Radio-Chemoembolization.
Antagonistic effect of nano-selenium on hepatocyte apoptosis induced by DEHP via PI3K/AKT pathway in chicken liver.
Supplementation of Saponins from Leaves of Panax quinquefolius Mitigates Cisplatin-Evoked Cardiotoxicity via Inhibiting Oxidative Stress-Associated Inflammation and Apoptosis in Mice.
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects.
Experimental study on the therapeutic effect and underlining mechanisms of positron in pancreatic cancer cells.
Liraglutide prevents fast weight gain and β-cell dysfunction in male catch-up growth rats.
Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina.
Vinyl chloride monomer (VCM) induces high occurrence of neural tube defects in embryonic mouse brain during neurulation.
RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells.
Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney.
A novel protein extracted from foxtail millet bran displays anti-carcinogenic effects in human colon cancer cells.
Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts.
Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.
BMP9-induced osteogenetic differentiation and bone formation of muscle-derived stem cells.
Study of the extraction process and in vivo inhibitory effect of ganoderma triterpenes in oral mucosa cancer.
Chen W, Zhang K, Cui H, Li J, Yao D, Wang S, Tian X, Kou W, Huang J, Wang H, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116276
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116276
Effects of alendronate on cartilage lesions and micro-architecture deterioration of subchondral bone in patellofemoral osteoarthritic ovariectomized rats with patella-baja.
Bei M, Zheng Z, Xiao Y, Liu N, Cao X, Tian F, Zhang L, Wu X
Journal of orthopaedic surgery and research 2024 Mar 25;19(1):197
Journal of orthopaedic surgery and research 2024 Mar 25;19(1):197
SHARPIN contributes to sevoflurane-induced neonatal neurotoxicity through up-regulating HMGB1 to repress M2 like-macrophage polarization.
Cai J, Lin Y, Zhou B, Xiao F, Xu G, Lu J
Metabolic brain disease 2024 Jun;39(5):841-853
Metabolic brain disease 2024 Jun;39(5):841-853
Cytisine-N-methylene-(5,7,4(')-trihydroxy)- isoflavone ameliorates ischemic stroke-induced brain injury in mouse by regulating the oxidative stress and BDNF-Trkb/Akt pathway.
Li Y, Fan F, Liu Q
European journal of pharmacology 2024 Jul 5;974:176512
European journal of pharmacology 2024 Jul 5;974:176512
Borneol-Modified Schisandrin B Micelles Cross the Blood-Brain Barrier To Treat Alzheimer's Disease in Aged Mice.
Li FR, Yu Y, Du YM, Kong L, Liu Y, Wang JH, Chen MH, Liu M, Zhang ZX, Li XT, Ju RJ
ACS chemical neuroscience 2024 Feb 7;15(3):593-607
ACS chemical neuroscience 2024 Feb 7;15(3):593-607
Hepatitis E virus causes apoptosis of ovarian cells in hens and resulting in a decrease in egg production.
Zhang Y, Gao X, Cao M, Xu H, Liu H, Zhao Q, Zhou EM, Chen Y, Liu B
Poultry science 2024 Apr;103(4):103501
Poultry science 2024 Apr;103(4):103501
A breakthrough in periodontitis treatment: Revealing the pharmacodynamic substances and mechanisms of Kouqiangjie formula.
Wu Y, Liu M, He X, Zhou H, Wei J, Li H, Yuan Q, Zuo Y, Zhao L, Xie Y
Journal of ethnopharmacology 2024 Apr 6;323:117738
Journal of ethnopharmacology 2024 Apr 6;323:117738
Mitochondrial Fission in Nickel Nanoparticle-Induced Reproductive Toxicity: An In Vitro GC-1 Cell Study.
Zheng H, Liang G, Guan C, Liu L, Dong J, Zhao J, Tang M, Kong L
Nanomaterials (Basel, Switzerland) 2024 Apr 17;14(8)
Nanomaterials (Basel, Switzerland) 2024 Apr 17;14(8)
(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells.
Zhang M, Li J, Ma R, Xi J, Xi L, Zhang B, Tian J, Bai Z
Chemistry & biodiversity 2023 Jul;20(7):e202300050
Chemistry & biodiversity 2023 Jul;20(7):e202300050
Hsa_circ_0001550 impairs decidualization by regulating the proliferation and apoptosis of endometrial stromal cells.
Lyu M, Gao W, Zhang L, Yang X, Yue F, Li H, Ma X, Liu L
Reproductive biomedicine online 2023 Feb;46(2):225-233
Reproductive biomedicine online 2023 Feb;46(2):225-233
Canagliflozin ameliorates high glucose-induced apoptosis in NRK-52E cells via inhibiting oxidative stress and activating AMPK/mTOR-mediated autophagy.
Liu H, Chen W, Wan S, Chen Y, Fu M, Wang Z, Xiong F, Zhang Y
Molecular biology reports 2023 Dec;50(12):10325-10337
Molecular biology reports 2023 Dec;50(12):10325-10337
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
Zhang Q, Qian D, Tang DD, Liu J, Wang LY, Chen W, Wu CJ, Peng W
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10782-10793
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10782-10793
Aconitine induces cell apoptosis via mitochondria and death receptor signaling pathways in hippocampus cell line.
Wang H, Liu Y, Guo Z, Wu K, Zhang Y, Tian Y, Zhao B, Lu H
Research in veterinary science 2022 Mar;143:124-133
Research in veterinary science 2022 Mar;143:124-133
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Bai X, Liu X, Li S, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Preparation of Nereid oligopeptide and investigation of the mechanism underlying the induction of apoptosis in human lung cancer H1299 cells.
Zhang G, Li H, Liu S, Lu M, Tang L, Sun L
Molecular medicine reports 2022 Jun;25(6)
Molecular medicine reports 2022 Jun;25(6)
Circular RNA Rbms1 inhibited the development of myocardial ischemia reperfusion injury by regulating miR-92a/BCL2L11 signaling pathway.
Jin L, Zhang Y, Jiang Y, Tan M, Liu C
Bioengineered 2022 Feb;13(2):3082-3092
Bioengineered 2022 Feb;13(2):3082-3092
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Sun M, Zhou D, Wu J, Zhou J, Xu J
Marine drugs 2022 Feb 5;20(2)
Marine drugs 2022 Feb 5;20(2)
Tanshinone IIA inhibits cardiomyocyte apoptosis and rescues cardiac function during doxorubicin-induced cardiotoxicity by activating the DAXX/MEK/ERK1/2 pathway.
Xu L, He D, Wu Y, Shen L, Wang Y, Xu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154471
Overexpression of miR-125a-5p Inhibits Hepatocyte Proliferation through the STAT3 Regulation In Vivo and In Vitro.
Zhang C, Zhao Y, Wang Q, Qin J, Ye B, Xu C, Yu G
International journal of molecular sciences 2022 Aug 4;23(15)
International journal of molecular sciences 2022 Aug 4;23(15)
Emodin Ameliorates Renal Damage and Podocyte Injury in a Rat Model of Diabetic Nephropathy via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway.
Liu H, Wang Q, Shi G, Yang W, Zhang Y, Chen W, Wan S, Xiong F, Wang Z
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:1253-1266
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:1253-1266
Highly Tumor-Specific and Long-Acting Iodine-131 Microbeads for Enhanced Treatment of Hepatocellular Carcinoma with Low-Dose Radio-Chemoembolization.
Qian Y, Liu Q, Li P, Han Y, Zhang J, Xu J, Sun J, Wu A, Song S, Lu W
ACS nano 2021 Feb 23;15(2):2933-2946
ACS nano 2021 Feb 23;15(2):2933-2946
Antagonistic effect of nano-selenium on hepatocyte apoptosis induced by DEHP via PI3K/AKT pathway in chicken liver.
Li H, Zhang J, Xia Y, Pan W, Zhou D
Ecotoxicology and environmental safety 2021 Apr 29;218:112282
Ecotoxicology and environmental safety 2021 Apr 29;218:112282
Supplementation of Saponins from Leaves of Panax quinquefolius Mitigates Cisplatin-Evoked Cardiotoxicity via Inhibiting Oxidative Stress-Associated Inflammation and Apoptosis in Mice.
Xing JJ, Hou JG, Liu Y, Zhang RB, Jiang S, Ren S, Wang YP, Shen Q, Li W, Li XD, Wang Z
Antioxidants (Basel, Switzerland) 2019 Sep 1;8(9)
Antioxidants (Basel, Switzerland) 2019 Sep 1;8(9)
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
Zhang Z, Wang J, Zhu Y, Zhang H, Wang H
Molecular medicine reports 2019 Nov;20(5):4612-4622
Molecular medicine reports 2019 Nov;20(5):4612-4622
WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects.
Guan F, Ding R, Zhang Q, Chen W, Li F, Long L, Li W, Li L, Yang D, Xie L, Yuan S, Wang L
Oncotarget 2017 Sep 22;8(42):71782-71796
Oncotarget 2017 Sep 22;8(42):71782-71796
Experimental study on the therapeutic effect and underlining mechanisms of positron in pancreatic cancer cells.
Wang Y, Li M, Diao R, Tung B, Zhang D, Li Y
Oncotarget 2017 Aug 1;8(31):51652-51662
Oncotarget 2017 Aug 1;8(31):51652-51662
Liraglutide prevents fast weight gain and β-cell dysfunction in male catch-up growth rats.
Zheng J, Chen T, Zhu Y, Li HQ, Deng XL, Wang QH, Zhang JY, Chen LL
Experimental biology and medicine (Maywood, N.J.) 2015 Sep;240(9):1165-76
Experimental biology and medicine (Maywood, N.J.) 2015 Sep;240(9):1165-76
Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina.
Li X, Wang L, Wang Z
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 2015 Jun;31(4):352-9
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 2015 Jun;31(4):352-9
Vinyl chloride monomer (VCM) induces high occurrence of neural tube defects in embryonic mouse brain during neurulation.
Quan H, Ma T, Zhao X, Zhao B, Liu Y, Li H
Cellular and molecular neurobiology 2014 May;34(4):619-30
Cellular and molecular neurobiology 2014 May;34(4):619-30
RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells.
Fu L, Zhang S
International journal of molecular medicine 2014 May;33(5):1153-60
International journal of molecular medicine 2014 May;33(5):1153-60
Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney.
Wei T, Tian W, Liu F, Xie G
Biochemical and biophysical research communications 2014 May 16;447(4):666-71
Biochemical and biophysical research communications 2014 May 16;447(4):666-71
A novel protein extracted from foxtail millet bran displays anti-carcinogenic effects in human colon cancer cells.
Shan S, Li Z, Newton IP, Zhao C, Li Z, Guo M
Toxicology letters 2014 Jun 5;227(2):129-38
Toxicology letters 2014 Jun 5;227(2):129-38
Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts.
Dong HY, Wang ZF
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2014 Apr;26(2):200-7
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2014 Apr;26(2):200-7
Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.
Yuan X, Sun Q, Ou Y, Wang S, Zhang W, Deng H, Wu X, Zhang L
Neural regeneration research 2014 Apr 15;9(8):837-44
Neural regeneration research 2014 Apr 15;9(8):837-44
BMP9-induced osteogenetic differentiation and bone formation of muscle-derived stem cells.
Xiang L, Liang C, Zhen-Yong K, Liang-Jun Y, Zhong-Liang D
Journal of biomedicine & biotechnology 2012;2012:610952
Journal of biomedicine & biotechnology 2012;2012:610952
Study of the extraction process and in vivo inhibitory effect of ganoderma triterpenes in oral mucosa cancer.
Gao Y, Zhang R, Zhang J, Gao S, Gao W, Zhang H, Wang H, Han B
Molecules (Basel, Switzerland) 2011 Jun 24;16(7):5315-32
Molecules (Basel, Switzerland) 2011 Jun 24;16(7):5315-32
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