Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- M00334-3 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-active Caspase-3 CASP3 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for CASPASE 3/CASP3 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF, IHC, ICC, WB. Reactive species: Human CASPASE 3/CASP3 information: Molecular Weight: 31608 MW; Subcellular Localization: Cytoplasm; Tissue Specificity: Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
- Reactivity
- Human
- Host
- Rabbit
- Antibody clone number
- HE-3
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references From gains to gaps? How Selective Androgen Receptor Modulator (SARM) YK11 impact hippocampal function: In silico, in vivo, and ex vivo perspectives.
The therapeutic effects of exosomes the first time isolated from pancreatic islet-derived progenitor cells in the treatment of pancreatic cancer.
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Long non-coding RNA ROR confers arsenic trioxide resistance to HepG2 cells by inhibiting p53 expression.
Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.
Acacetin-induced cell apoptosis in head and neck squamous cell carcinoma cells: Evidence for the role of muscarinic M3 receptor.
Trimebutine Promotes Glioma Cell Apoptosis as a Potential Anti-tumor Agent.
Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress.
Recombinant Newcastle disease virus expressing human IFN-λ1 (rL-hIFN-λ1)-induced apoptosis of A549 cells is connected to endoplasmic reticulum stress pathways.
Involvement of substance p/neurokinin-1 receptor in the analgesic and anticancer activities of minimally toxic fraction from the traditional Chinese medicine Liu-Shen-Wan in vitro.
RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells.
Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts.
Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.
Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism.
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
Dahleh MMM, Bortolotto VC, Boeira SP, Segat HJ, Guerra GP, Prigol M
Chemico-biological interactions 2024 May 1;394:110971
Chemico-biological interactions 2024 May 1;394:110971
The therapeutic effects of exosomes the first time isolated from pancreatic islet-derived progenitor cells in the treatment of pancreatic cancer.
Hasoglu I, Karatug Kacar A
Protoplasma 2024 Mar;261(2):281-291
Protoplasma 2024 Mar;261(2):281-291
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
Zhang Q, Qian D, Tang DD, Liu J, Wang LY, Chen W, Wu CJ, Peng W
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10782-10793
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10782-10793
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Sun M, Zhou D, Wu J, Zhou J, Xu J
Marine drugs 2022 Feb 5;20(2)
Marine drugs 2022 Feb 5;20(2)
Long non-coding RNA ROR confers arsenic trioxide resistance to HepG2 cells by inhibiting p53 expression.
Li X, Sun D, Zhao T, Zhang Z
European journal of pharmacology 2020 Apr 5;872:172982
European journal of pharmacology 2020 Apr 5;872:172982
Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.
Li Y, Huang T, Fu Y, Wang T, Zhao T, Guo S, Sun Y, Yang Y, Li C
PloS one 2019;14(9):e0215886
PloS one 2019;14(9):e0215886
Acacetin-induced cell apoptosis in head and neck squamous cell carcinoma cells: Evidence for the role of muscarinic M3 receptor.
Sun F, Li D, Wang C, Peng C, Zheng H, Wang X
Phytotherapy research : PTR 2019 May;33(5):1551-1561
Phytotherapy research : PTR 2019 May;33(5):1551-1561
Trimebutine Promotes Glioma Cell Apoptosis as a Potential Anti-tumor Agent.
Fan YP, Liu P, Xue WK, Zhao WJ, Pan HC
Frontiers in pharmacology 2018;9:664
Frontiers in pharmacology 2018;9:664
Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress.
Zhao C, Lin M, Pan Y, Yu B
Gastroenterology research and practice 2018;2018:9252984
Gastroenterology research and practice 2018;2018:9252984
Recombinant Newcastle disease virus expressing human IFN-λ1 (rL-hIFN-λ1)-induced apoptosis of A549 cells is connected to endoplasmic reticulum stress pathways.
Yan Y, Liu S, Li M, Zhao Y, Shao X, Hang M, Bu X
Thoracic cancer 2018 Nov;9(11):1437-1452
Thoracic cancer 2018 Nov;9(11):1437-1452
Involvement of substance p/neurokinin-1 receptor in the analgesic and anticancer activities of minimally toxic fraction from the traditional Chinese medicine Liu-Shen-Wan in vitro.
Li XJ, Jia MM, Li YS, Yang YL, Mao XQ, Tang HB
Biological & pharmaceutical bulletin 2014;37(3):431-8
Biological & pharmaceutical bulletin 2014;37(3):431-8
RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells.
Fu L, Zhang S
International journal of molecular medicine 2014 May;33(5):1153-60
International journal of molecular medicine 2014 May;33(5):1153-60
Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts.
Dong HY, Wang ZF
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2014 Apr;26(2):200-7
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2014 Apr;26(2):200-7
Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.
Yuan X, Sun Q, Ou Y, Wang S, Zhang W, Deng H, Wu X, Zhang L
Neural regeneration research 2014 Apr 15;9(8):837-44
Neural regeneration research 2014 Apr 15;9(8):837-44
Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism.
Chang C, Liu SP, Fang CH, He RS, Wang Z, Zhu YQ, Jiang SW
Oncology letters 2013 Sep;6(3):699-704
Oncology letters 2013 Sep;6(3):699-704
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
Zhou Y, Li W, Xu Q, Huang Y
Journal of experimental & clinical cancer research : CR 2010 Oct 4;29(1):131
Journal of experimental & clinical cancer research : CR 2010 Oct 4;29(1):131
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of active Caspase-3 expression in Jurkat cell lysate treated with Camptothecin.
- Additional image