orb1951945

antibody from Biorbyt

Targeting: CASP3 apopain, CPP32, CPP32B, Yama

Western blot

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Flow cytometry

Antibody data

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Validation data

Product number: orb1951945 - Provider product page
Provider: Biorbyt
Product name: Caspase-3 Rabbit mAb [KD Validated]
Antibody type: Recombinant
Description: Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Vial size: 50 ul
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

CASP3 protein structure - orb1951945 shown in red.