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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [23]
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- Validations
- Immunohistochemistry [1]
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- Product number
- PA1302-1 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Caspase-3 (P10)/CASP3 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for CASPASE 3/CASP3 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CASPASE 3/CASP3 information: Molecular Weight: 31608 MW; Subcellular Localization: Cytoplasm; Tissue Specificity: Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Hepatitis E virus causes apoptosis of ovarian cells in hens and resulting in a decrease in egg production.
miR-466 Contributes to the Enhanced Antitumor Effect of Bortezomib on Non-Small-Cell Lung Cancer by Inhibiting CCND1.
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
Cryptotanshinone ameliorates MPP(+)-induced oxidative stress and apoptosis of SH-SY5Y neuroblastoma cells: the role of STAT3 in Parkinson's disease.
Molybdenum Diphosphide Nanorods with Laser-Potentiated Peroxidase Catalytic/Mild-Photothermal Therapy of Oral Cancer.
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Investigation of Lonicera japonica Flos against Nonalcoholic Fatty Liver Disease Using Network Integration and Experimental Validation.
Polydatin induces apoptosis and autophagy via STAT3 signaling in human osteosarcoma MG-63 cells.
Cordyceps sinensis polysaccharide inhibits colon cancer cells growth by inducing apoptosis and autophagy flux blockage via mTOR signaling.
Effects of carboxymethyl chitosan oligosaccharide on regulating immunologic function and inhibiting tumor growth.
Low expression of miR-1 promotes osteogenic repair of bone marrow mesenchymal stem cells by targeting TLR1.
Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia.
Oxymatrine inhibits proliferation of human bladder cancer T24 cells by inducing apoptosis and cell cycle arrest.
Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir.
Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway.
RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells.
Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts.
Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.
Modulating Bcl-2 family proteins and caspase-3 in induction of apoptosis by paeoniflorin in human cervical cancer cells.
Pathway of programmed cell death in HeLa cells induced by polymeric anti-cancer drugs.
7-difluoromethyl-5,4'-dimethoxygenistein, a novel agent protecting against vascular endothelial injury caused by oxidative stress.
Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride.
Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells.
Zhang Y, Gao X, Cao M, Xu H, Liu H, Zhao Q, Zhou EM, Chen Y, Liu B
Poultry science 2024 Apr;103(4):103501
Poultry science 2024 Apr;103(4):103501
miR-466 Contributes to the Enhanced Antitumor Effect of Bortezomib on Non-Small-Cell Lung Cancer by Inhibiting CCND1.
Wang WH, Zhan JM, Tang YL, Zhou N, Liu WY, Jiang DW
Chemotherapy 2022;67(2):110-122
Chemotherapy 2022;67(2):110-122
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
Zhang Q, Qian D, Tang DD, Liu J, Wang LY, Chen W, Wu CJ, Peng W
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10782-10793
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10782-10793
Cryptotanshinone ameliorates MPP(+)-induced oxidative stress and apoptosis of SH-SY5Y neuroblastoma cells: the role of STAT3 in Parkinson's disease.
Wang Q, Liu Y
Metabolic brain disease 2022 Jun;37(5):1477-1485
Metabolic brain disease 2022 Jun;37(5):1477-1485
Molybdenum Diphosphide Nanorods with Laser-Potentiated Peroxidase Catalytic/Mild-Photothermal Therapy of Oral Cancer.
Qian M, Cheng Z, Luo G, Galluzzi M, Shen Y, Li Z, Yang H, Yu XF
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(1):2101527
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(1):2101527
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Sun M, Zhou D, Wu J, Zhou J, Xu J
Marine drugs 2022 Feb 5;20(2)
Marine drugs 2022 Feb 5;20(2)
Investigation of Lonicera japonica Flos against Nonalcoholic Fatty Liver Disease Using Network Integration and Experimental Validation.
Sun CY, Zhao P, Yan PZ, Li J, Zhao DS
Medicina (Kaunas, Lithuania) 2022 Aug 30;58(9)
Medicina (Kaunas, Lithuania) 2022 Aug 30;58(9)
Polydatin induces apoptosis and autophagy via STAT3 signaling in human osteosarcoma MG-63 cells.
Jiang CQ, Ma LL, Lv ZD, Feng F, Chen Z, Liu ZD
Journal of natural medicines 2020 Jun;74(3):533-544
Journal of natural medicines 2020 Jun;74(3):533-544
Cordyceps sinensis polysaccharide inhibits colon cancer cells growth by inducing apoptosis and autophagy flux blockage via mTOR signaling.
Qi W, Zhou X, Wang J, Zhang K, Zhou Y, Chen S, Nie S, Xie M
Carbohydrate polymers 2020 Jun 1;237:116113
Carbohydrate polymers 2020 Jun 1;237:116113
Effects of carboxymethyl chitosan oligosaccharide on regulating immunologic function and inhibiting tumor growth.
Jiang Z, Wang S, Hou J, Chi J, Wang S, Shao K, Liu W, Sun R, Han B
Carbohydrate polymers 2020 Dec 15;250:116994
Carbohydrate polymers 2020 Dec 15;250:116994
Low expression of miR-1 promotes osteogenic repair of bone marrow mesenchymal stem cells by targeting TLR1.
Wang JG, Zhao XG, Wang XL, Liu MX, Wan W
European review for medical and pharmacological sciences 2020 Apr;24(7):3492-3500
European review for medical and pharmacological sciences 2020 Apr;24(7):3492-3500
Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia.
Wei X, Zhu Q, Liu N, Xu L, Wei S, Fan Z, Sun C, Zhao Y, Qiao M, Wu J, Hu D, Wang Y, Sun P
Frontiers in pharmacology 2019;10:1096
Frontiers in pharmacology 2019;10:1096
Oxymatrine inhibits proliferation of human bladder cancer T24 cells by inducing apoptosis and cell cycle arrest.
Li S, Zhang Y, Liu Q, Zhao Q, Xu L, Huang S, Huang S, Wei X
Oncology letters 2017 Jun;13(6):4453-4458
Oncology letters 2017 Jun;13(6):4453-4458
Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir.
Zhou H, He Z, Wang C, Xie T, Liu L, Liu C, Song F, Ma Y
International journal of molecular sciences 2016 Jun 6;17(6)
International journal of molecular sciences 2016 Jun 6;17(6)
Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway.
Huang KF, Huang XP, Xiao GQ, Yang HY, Lin JS, Diao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 May;68(4):455-61
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 May;68(4):455-61
RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells.
Fu L, Zhang S
International journal of molecular medicine 2014 May;33(5):1153-60
International journal of molecular medicine 2014 May;33(5):1153-60
Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts.
Dong HY, Wang ZF
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2014 Apr;26(2):200-7
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2014 Apr;26(2):200-7
Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.
Yuan X, Sun Q, Ou Y, Wang S, Zhang W, Deng H, Wu X, Zhang L
Neural regeneration research 2014 Apr 15;9(8):837-44
Neural regeneration research 2014 Apr 15;9(8):837-44
Modulating Bcl-2 family proteins and caspase-3 in induction of apoptosis by paeoniflorin in human cervical cancer cells.
Zhang L, Zhang S
Phytotherapy research : PTR 2011 Oct;25(10):1551-7
Phytotherapy research : PTR 2011 Oct;25(10):1551-7
Pathway of programmed cell death in HeLa cells induced by polymeric anti-cancer drugs.
Guan YQ, Li Z, Chen J, Tao H, Wang W, Zheng Z, Li L, Liu JM
Biomaterials 2011 May;32(14):3637-46
Biomaterials 2011 May;32(14):3637-46
7-difluoromethyl-5,4'-dimethoxygenistein, a novel agent protecting against vascular endothelial injury caused by oxidative stress.
Wang L, Zheng X, Xiang HL, Fu XH, Cao JG
Clinical and experimental pharmacology & physiology 2009 Dec;36(12):e90-5
Clinical and experimental pharmacology & physiology 2009 Dec;36(12):e90-5
Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride.
Tan CB, Gao M, Xu WR, Yang XY, Zhu XM, Du GH
Biological & pharmaceutical bulletin 2009 Aug;32(8):1359-63
Biological & pharmaceutical bulletin 2009 Aug;32(8):1359-63
Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells.
Wu YF, Cao MF, Gao YP, Chen F, Wang T, Zumbika EP, Qian KX
World journal of gastroenterology 2004 Oct 15;10(20):2944-8
World journal of gastroenterology 2004 Oct 15;10(20):2944-8
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-Caspase-3(P10), PA1302-1, IHC(P)IHC(P): Human Intestinal Cancer Tissue
- Additional image
