10712-1-AP

antibody from Proteintech Group

Targeting: KRT19 CK19, K19, K1CS, MGC15366

Provider product page for 10712-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [206]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [1]
Flow cytometry [1]

Submit

Product number: 10712-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10712-1-AP, RRID:AB_2133325
Product name: Cytokeratin 19 antibody
Antibody type: Polyclonal
Description: Cytokeratin 19 antibody (Cat. #10712-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

KRT19 protein structure - 10712-1-AP shown in red.

Submitted references Dietary Lauric Acid Suppresses Inflammation, Cholestasis, Hepatocyte Injury, and Senescence in 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-induced Inflammatory Cholangiopathy.

Ghosh S, Devereaux MW, Anderson AL, Anderson CC, D'Alessandro A, Orlicky DJ, Sokol RJ
Cellular and molecular gastroenterology and hepatology 2026;20(5):101731

GCDCA promotes hepatocellular carcinoma progression through S1PR2/PI3K/AKT-mediated polarization of M2-type macrophages.

Xue M, Yu W, Zhang K, Chen Y, Zhang L, Zhang H, Lu S, Tao M, Yan H, Wei L, Lv G, Gao L, Zhang L
Frontiers in immunology 2026;17:1640450

Multi-omics profiling reveals cholic acid-mediated immunosuppression driven by peritumoral ductular reactions in hepatocellular carcinoma.

Xu Q, Chen H, Wang G, Wang X, Shi J, Cheng Y, Xu Y, Ma S, Guo S, Liu X, Gao Q, Song G
Cancer letters 2026 May 28;646:218393

ISG15 deficiency in hepatic stellate cells promotes TGFβ2-induced liver fibrosis by counteracting CREB1 ISGylation.

Yuan Y, Li J, Rao D, Lu X, Chen M, Chen X, Long X, Zhang B, Liang H, Chen Q, Zhao J
Gut 2026 May 12;75(6):1186-1200

Anti-skin aging effects of black ginseng extracts through regulating inflammatory factors and the CLOCK-ERK pathway in mice.

Huang Y, Wang B, Jin Y, Qiu M, Liu J, Hao L, Zhang C, Ma H
Journal of ginseng research 2026 Mar;50(2):100926

Metformin suppresses PPARδ-driven CD47 transcription to enhance macrophage phagocytosis in lung cancer.

Cui Q, Wang H, Yu H, Li Y, Wang Y, Shi J, Hou Y
The Journal of biological chemistry 2026 Mar;302(3):111159

Natural photosynthetic system for restoring homeostasis of animal organelle interaction network.

Xia C, Dai Z, Wang Y, Yu J, Wang Z, Huang Z, Pan K, Yang K, Chen Y, Zhong P, Gu C, Fan S, Lin X, Chen P
Nature communications 2026 Mar 31;17(1)

A spatiotemporal transcriptomic atlas of porcine (Sus scrofa) female early gonadal development.

He P, Xia W, Chen T, Yan Y, Gao D, Teng Y, Zhao T, Chen X, Feng Z, Li R, Wang M, Ke Y, Han J
Communications biology 2026 Mar 30;9(1)

NCOA4-mediated ferritinophagy modulates colitis-associated ferroptosis in intestinal epithelial cells and mucosal repair.

Huang Q, Liu L, Zhao Y, Xiao J, Yang Y, Hong Y, Ji H, Wu H, Ma X, Zhang D
Biology direct 2026 Mar 12;21(1)

Total astragalus saponins enhance the anti-liver fibrosis efficacy of Numb-overexpressed hUC-MSCs through stabilizing the Numb-p53 axis.

Zhang SH, Yang MY, Xu YN, Xing FF, Zhan JY, Wang DX, Chen JM, Chen GF, Liu P, Liu W, Mu YP
Journal of ethnopharmacology 2026 Mar 1;358:120980

Senkyunolide A interrupts TRAF6-HDAC3 interaction to epigenetically suppress c-MYC and attenuate cholestatic liver injury.

Li Y, Liu R, Li J, Gao F, Ma Z, Xie K, Li F, Xu B, Zheng Q, Cai Y, Qu J, Xue X, Jia K, Li X
Journal of advanced research 2026 Jan;79:935-951

CDX2 Promotes Hepatic Specification of hiPSC-derived Endoderm Through the PI3K-Akt-GSK3β Pathway for Improved Therapeutic Efficacy.

Bai F, Duan J, Yang D, Lai X, Ji H, Zhu X, He X, Hu A
Stem cell reviews and reports 2026 Jan;22(1):503-522

Isolation and long-term culture of primary mouse cholangiocytes that retain biophysical properties and distinct Cl-conductances: An initial study.

Li Q, Wang Y, Boggs K, Kresge C, Nejak-Bowen K
Physiological reports 2026 Jan;14(2):e70732

Investigation into the Pancreatic Pathogenesis of SFTSV across Multiple Levels.

Liu X, Xu Z, Tong Y, Wang C, Yao Y, Diao Y, Ma J, Zhou S, Du Y, Zhang Z, Xu G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e15862

The Mechanism of Ultrasonic Lysis of Enterococcus faecium F11.1G in Repairing LPS-Induced Inflammatory Damage in IECs via RNA-seq and LC-MS.

Bai T, Zhang Y, E G, Zhang M, Guo X, Liu J
Cells 2026 Jan 6;15(2)

USP21 deubiquitinates DPYSL2 and enhances its centrosomal abundance to promote cilium formation.

Song T, Zhou P, Zhang F, Liu C, Han X, Yue Y, Hu M, Yan S, Li Q, Liu M, Zhou J, Zhao H
Journal of genetics and genomics = Yi chuan xue bao 2026 Feb;53(2):256-268

Fibroblast Growth Factor 11 Improves Fertility by Alleviating Intrauterine Adhesionss in Rats Through Inhibition of the Transforming Growth Factor-β1/Smad Pathway.

Yin F, Fang Q, Liu X, Yu X, Rong Y, Shi D, Xu Z, Gong F, Chen M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71602

Cancer-Associated fibroblasts regulate the development of cholangiocarcinoma through IL-6/STAT3/AKR1C3 signaling axis.

Huang TC, Feng WD, Fang GX, Zhang QH, Wei GY, Li CZ, Wang JM, Liu JF
Scientific reports 2026 Feb 25;16(1)

Cancer-Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT-ANGPTL4 Axis.

Lu S, Ke S, Yu H, Meng Z, Bai M, Xu Y, Zhu H, Yang J, Qian B, Yin B, Wang C, Feng Z, Li Z, Zhou Y, Li Z, Li X, Hua Y, Fu Y, Tang W, Wu Y, Ma Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 14;:e21418

Integrated transcriptome and proteome analysis identifies keratins as key regulators of corneal scarring in a murine model.

Zhou T, Cai Y, Fang F, Cai X, Fu Y
Computational and structural biotechnology journal 2025;27:2264-2274

HDAC4/MybL1/YAP novel signaling axis is required for pancreatic cancer metastasis to the liver.

Edderkaoui M, Elmadbouh OHM, Lim A, Ou Y, Hauptschein D, Guha A, Darwish A, Calsavara VF, Murali R, Bhowmick N, Osipov A, Mathison AJ, Urrutia R, Wang Q, Pandol SJ
International journal of biological sciences 2025;21(15):6907-6925

Quercetin promotes production of secondary hair follicle stem cells in cashmere goat: a mechanistic study.

Lian W, Jiang G, Wu X, Gao Y, Cui K, Zhu L, Xu Z, Zhang X, Wang J, Peng M, Ding R, Hao F, Liu D
Frontiers in veterinary science 2025;12:1689059

Aluminum adjuvant promotes liver inflammation and fibrosis in mice: A novel approach to establish a liver fibrosis animal model.

Zhu Z, Liang S, Zhao N, Zou H, Zhang L, Zhang X, Chai J
Liver research (Beijing, China) 2025 Sep;9(3):209-220

Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.

Xia W, Yao H, Mu T, Liu H, Chen J, Feng S, Wen S
Experimental and therapeutic medicine 2025 Sep;30(3):167

Disruption of Bile Acid Metabolism in the Gut-Liver Axis Predisposes Mice to Inflammatory Bowel Disease.

Chang H, Jiang Y, Zhao Q, Su Z, Chen M, He Q, Lai J, Jiang Y, Zheng J, Pan R, Shao J, Zhao RC, Chen Y
MedComm 2025 Oct;6(10):e70429

Capsaicin ameliorates cholestasis through modulation of the FXR-SHP and FXR-FGF15 gut-liver axis in mice.

Du H, Luo Y, Zhou N, Wang T, Wang R, Wang Y, Lv C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157130

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma.

Zhang S, Jiang L, Cai S, Weng Z, Zhu Y, Cai ZW, Li H, Li Q, Hu LP, Yao HF, Hua R, Zhao Y, Li D, Yang XM, Zhang JF, Jiang SH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11726

A Multifunctional Molecular Probe for Multimodal Imaging-Guided Potent Photothermal/Photodynamic Therapy of Endometriosis.

Zhong Q, Yang S, Li X, Jin Z, Ma J, Liao Z, Li J, Li B, Shuai X, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e11126

m(6)A demethylase FTO drives pancreatic ductal adenocarcinoma tumorigenesis and metastasis through remodeling PFKM mediated glycolysis.

Tan Z, Yang J, Chen Y, Zhu H, Liu X, Xu H, Meng Q, Xiao M, Tang R, Rong Z, Yu X, Liang C, Xu J
Cell death & disease 2025 Nov 3;16(1):784

CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription.

Miao K, Zhou J, Chen J
Hereditas 2025 Nov 26;162(1):233

Numb-exon3 and full length Numb equivalently alleviate cholestatic liver fibrosis by inhibiting ductular reaction.

Xu YN, Zong MY, Xu W, Zhang SH, Wang DY, Zheng XR, Xing FF, Zhan JY, Chen JM, Chen GF, Liu P, Liu W, Mu YP
Scientific reports 2025 Nov 14;15(1):39983

PPDPF-mediated regulation of BCAA metabolism enhances mTORC1 activity and drives cholangiocarcinoma progression.

Li Z, Guan Y, Gao J, Zhu L, Zeng Z, Jing Q, Wan Q, Fan Q, Ren X, Pei H, Zhang D, Rong Y, Rong Z, He J, Zhang Y, Li N, Chen P, Sun L, Xu B, Nie Y, Deng Y
Oncogene 2025 May;44(19):1415-1433

Modeling hepatic steatosis with human adult stem cell-derived liver organoids.

Zhu L, Liu S, Wang Z, Yang Y, Han P, Tong W, Zhao T, Wang L, Cui T, Yang L, Zhang Y
iScience 2025 May 16;28(5):112344

Basal and AT2 cells promote IPF-lung cancer co-occurrence via EMT: Single-cell analysis.

Ren C, Zi Y, Zhang X, Liao X, Chen H
Experimental cell research 2025 May 15;448(2):114578

A facile liquid biopsy assay for highly efficient CTCs capture and reagent-less monitoring of immune checkpoint PD-L1 expression on CTCs with non-small cell lung cancer patients.

Liu Y, Zhang B, Wu X, Wang F, Yang Z, Li M, Sheng K, Yan Y, Zhu L, Jing H, Wu Y, Hu L, Yu Y, Li C
Biosensors & bioelectronics 2025 May 1;275:117236

IL-15 functionalized biomimetic hybrid mRNA vaccine for enhanced NSCLC immunotherapy via synergistic activation of T cells and NK cells.

Guo J, Peng L, Ma P, Mai Y, Gao T, Yu N, Zuo W, Yang J
Materials today. Bio 2025 Jun;32:101914

Transcription factor SP1 drives TGF-β1-induced transformation of human tenon's capsule fibroblasts by transcription activation-mediated SNAI2 upregulation.

Chen Y, Chen Y, Li C, Bai Z, Yang H, Wang Q, Zhang Y
International ophthalmology 2025 Jun 12;45(1):243

The effects of GnRH analogues on endometrial receptivity: a comprehensive study.

He Z, Guo N, Yao Y, Zhou J, Deng T, Du Y, Li Y, Yin L
Journal of assisted reproduction and genetics 2025 Jul;42(7):2313-2323

KEAP1 retention in phase-separated p62 bodies drives liver damage under autophagy-deficient conditions.

Takada S, Shinomiya N, Mao G, Tsuchiya H, Koga T, Komatsu-Hirota S, Sou YS, Abe M, Ryzhii E, Suzuki M, Nakao M, Waguri S, Morishita H, Komatsu M
EMBO reports 2025 Jul;26(13):3384-3410

Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.

Zeng Y, Yang Y, Zeng F, Feng Q
mSystems 2025 Jul 22;10(7):e0169224

Application and mechanism of anticancer peptides in organoid models of intrahepatic cholangiocarcinoma.

Hu X, Zhang Y, Li Y, Zheng Q, Zhao H, Zhang Y, Ni J, Yao J
Scientific reports 2025 Jul 2;15(1):22870

Single-cell transcriptomic analysis of the senescent microenvironment in bone metastasis.

Wang S, Ao L, Lin H, Wei H, Wu Z, Lu S, Liang F, Shen R, Zhang H, Miao T, Shen X, Lin J, Zhong G
Cell proliferation 2025 Jan;58(1):e13743

Si-Ni-San ameliorates cholestatic liver injury by favoring P. goldsteinii colonization.

Li F, Han Q, Cai Y, Li Y, Yang Y, Li J, Wu R, Chen R, Liu R
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118804

N(6)-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism.

Chen B, Li L, Huang Y, Ma J, Ji F, Chen Y, Wu L, Peng H
Cell reports 2025 Jan 28;44(1):115139

Dysregulated Activation of Hippo-YAP1 Signaling Induces Oxidative Stress and Aberrant Development of Intrahepatic Biliary Cells in Biliary Atresia.

Xie H, Zhu Z, Tang J, Zhu W, Zhu M, Yi Wai AW, Li J, Wu Z, Tam PKH, Lui VCH, Tang W
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102199

Plasma-activated solutions prevent peritoneal adhesion formation by regulating eNOS expression in mesothelial cells.

Ma Y, Sun T, Ren K, Ma R, Min T, Wang X, Yuan Y, Xie X, Zhang B, Deng X, Peng Y, Liu Y, Nan Y, Wang W, Zhou Z, Xu G, Li K, Zhu K, Hao N, Dang C, Zhang G, Zhang H
Journal of advanced research 2025 Dec;78:555-571

TAF15 in tumor-associated macrophages enhances protumorigenic polarization and promotes cholangiocarcinoma progression.

Liu Y, Xu B, Zhao T, Liu H, Pan Y, Zhao S, Chen Q, Wang L, Bai G, Zhang N, Zhou Y, Wei J, Fu X, Zhou Y, Wang Z, Xu L, Zhu Y, Shen S, Yang S, Zhou L, Wang L
JHEP reports : innovation in hepatology 2025 Dec;7(12):101545

Structure and thickness of Glisson's capsule differ considerably on the liver surface in mammalian species.

Uchida H, Aihara N, Morimura T, Matsumoto S, Hasegawa D, Ichiki T, Okamura E, Muto M, Sugahara G, Miki T, Ema M, Watanabe K, Kamiie J, Asahina K
Anatomical record (Hoboken, N.J. : 2007) 2025 Dec;308(12):3283-3296

REG3A promotes gemcitabine resistance in pancreatic cancer via the GPR54/ARRB2/ERK1/2 ligand-directed signaling pathway.

Liu J, Li S, Zhou H, Wang M, Zhang C, Tian C, Xu Y, Wang M, Li X, Li Q, Xiang M
Biochemical pharmacology 2025 Dec;242(Pt 2):117322

Evaluation of anti-tumor activity of borated camptothecin derivatives targeting topoisomerase 1 against hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

Zhang M, Xiang Y, Li C, Xu C, Chen G, Long R, Chen C, Liu Y, Ye F
Bioorganic chemistry 2025 Dec;167:109186

Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.

Cheng K, Liu L, Gong M, Ji Y, Bai C, Guo X, Chen H, Pan J, Zhang Y, Yuan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575

Lactylation-driven KRT19 promotes non-small cell lung cancer progression by suppressing cellular senescence.

Zhang C, Du Y, Ji Y, Ye X, Lian J, Zhou H, Gao Z, Xu H, Tang Y, Fan Y, Zheng L
Journal of experimental & clinical cancer research : CR 2025 Dec 4;45(1):13

RalGAP complexes control secretion and primary cilia in pancreatic disease.

Apken LH, Barz H, Beel S, Michalke E, Rasche R, Verma A, Ricker A, Nüsse H, Klingauf J, Kerl K, Wardelmann E, Kümmel D, Steinestel K, Pethő Z, Meisterernst M, Oeckinghaus A
Life science alliance 2025 Aug;8(8)

M1-BMDMs with Wnt5a deletion attenuate liver fibrosis by suppression of Wnt5a/Frizzled 2 axis in hepatic progenitors.

Xing FF, Wang DY, Xu YN, Zheng XR, Zhang SH, Zong MY, Zhan JY, Wang DX, Liu W, Chen JM, Chen GF, Liu P, Liu CH, Mu YP
Cell & bioscience 2025 Aug 30;15(1):125

USP18 promotes ferroptosis in lipopolysaccharide-induced human kidney organoids by stabilizing STING1.

Yang H, Zhao L, Kong W, Liu S, Zhou Q, Lang X, Lan L, Wang Y
Cell biology and toxicology 2025 Aug 20;41(1):126

Evolutionary fingerprints of epithelial-to-mesenchymal transition.

Perelli L, Zhang L, Mangiameli S, Giannese F, Mahadevan KK, Peng F, Citron F, Khan H, Le C, Gurreri E, Carbone F, Russell AJC, Soeung M, Lam TNA, Lundgren S, Marisetty S, Zhu C, Catania D, Mohamed AMT, Feng N, Augustine JJ, Sgambato A, Tortora G, Draetta GF, Tonon G, Futreal A, Giuliani V, Carugo A, Viale A, Kim MP, Heffernan TP, Wang L, Kalluri R, Cittaro D, Chen F, Genovese G
Nature 2025 Apr;640(8060):1083-1092

USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer.

Wang G, Dai S, Chen J, Zhang K, Huang C, Zhang J, Xie K, Lin F, Wang H, Gao Y, Yin L, Jiang K, Miao Y, Lu Z
Cell death and differentiation 2025 Apr;32(4):702-713

SRSF12 deficiency enhances tumor innervation and accelerates pancreatic tumorigenesis.

Yang MW, Jia QY, Xu DP, Xu YN, Huo YM, Liu DJ, Yang JY, Fu XL, Ma D, Duan ZH, Yin YF, Ma XS, Xu K, Hua R, Zhang JF, Sun YW, Liu W
Cancer letters 2025 Apr 28;616:217563

Exploring the mechanisms of Chaige Kangyi Recipe in treating recurrent pregnancy loss with insulin resistance.

Wu J, Pan Y, Lu Y, Qian J, Zhang J, Xue Y, Xiao C, Qiu Y, Xie M, Li S
Scientific reports 2025 Apr 22;15(1):13866

The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway.

Li X, Wang S, Cao H, Xu S, Xiong C, Yu J, Chen Y, Ren Z, Li M, Hu Y, Gan P, Xu Q, Wang Y, Liao H
Journal of translational medicine 2025 Apr 10;23(1):423

Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy.

Li X, Xiong C, Wang S, Ren Z, Jin Q, Yu J, Chen Y, Gan P, Xu Q, Wang Y, Liao H
Frontiers in immunology 2024;15:1422497

STRIP2 is regulated by the transcription factor Sp1 and promotes lung adenocarcinoma progression via activating the PI3K/AKT/mTOR/MYC signaling pathway.

Pan J, Zhang Y, He L, Wu Y, Xiao W, Zhang J, Xu Y
Genomics 2024 Sep;116(5):110923

An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration.

Thowfeequ S, Fiorentino J, Hu D, Solovey M, Ruane S, Whitehead M, Zhou F, Godwin J, Mateo-Otero Y, Vanhaesebroeck B, Scialdone A, Srinivas S
Developmental cell 2024 Sep 9;59(17):2347-2363.e9

LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury.

Lin S, Ren Z, Li L, Xia S, Yang R, Ye H
Scientific reports 2024 Nov 19;14(1):28578

Multi-omics-driven discovery of invasive patterns and treatment strategies in CA19-9 positive intrahepatic cholangiocarcinoma.

Ma D, Wei P, Liu H, Hao J, Chen Z, Chu Y, Li Z, Shi W, Yuan Z, Cheng Q, Gao J, Zhu J, Li Z
Journal of translational medicine 2024 Nov 15;22(1):1031

Exosomal lncRNA XIST promotes perineural invasion of pancreatic cancer cells via miR-211-5p/GDNF.

Cheng K, Pan J, Liu Q, Ji Y, Liu L, Guo X, Wang Q, Li S, Sun J, Gong M, Zhang Y, Yuan Y
Oncogene 2024 May;43(18):1341-1352

Bortezomib in previously treated phosphatase and tension homology-deficient patients with advanced intrahepatic cholangiocarcinoma: An open-label, prospective and single-centre phase II trial.

Zeng TM, Jiang TY, Yang G, Cheng Z, Lou C, Wei W, Tao CJ, Hu S, Wang H, Cui XW, Tan YX, Dong LW, Wang HY, Yuan ZG
Clinical and translational medicine 2024 May;14(5):e1675

Inflammation and Acinar Cell Dual-Targeting Nanomedicines for Synergistic Treatment of Acute Pancreatitis via Ca(2+) Homeostasis Regulation and Pancreas Autodigestion Inhibition.

Wang Y, Wang X, Zhang X, Zhang B, Meng X, Qian D, Xu Y, Yu L, Yan X, He Z
ACS nano 2024 May 7;18(18):11778-11803

Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.

Huang X, Yang X, Huang J, Wei L, Mao Y, Li C, Zhang Y, Chen Q, Wu S, Xie L, Sun C, Zhang W, Wang J
Cell communication and signaling : CCS 2024 May 31;22(1):301

LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway.

Qin X, Zeng B, Sooranna SR, Li M
Cell biochemistry and biophysics 2024 Mar;82(1):127-137

NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.

Zhang Z, Song B, Wei H, Liu Y, Zhang W, Yang Y, Sun B
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040

Danhongqing formula alleviates cholestatic liver fibrosis by downregulating long non-coding RNA H19 derived from cholangiocytes and inhibiting hepatic stellate cell activation.

Li M, Zhou Y, Zhu H, Xu LM, Ping J
Journal of integrative medicine 2024 Mar;22(2):188-198

Reprogramming canine cryopreserved hepatocytes to hepatic progenitor cells using small molecule compounds.

Yamazaki Y, Kikuchi K, Yamada Y, Neo S, Nitta S, Igarashi H, Kamiya A, Hisasue M
Regenerative therapy 2024 Jun;26:1078-1086

The lncRNA LINC01605 promotes the progression of pancreatic ductal adenocarcinoma by activating the mTOR signaling pathway.

Zhu YH, Jia QY, Yao HF, Duan ZH, Ma XS, Zheng JH, Yin YF, Liu W, Zhang JF, Hua R, Ma D, Sun YW, Yang JY, Liu DJ, Huo YM
Cancer cell international 2024 Jul 24;24(1):262

Biomimetic Trypsin-Responsive Structure-Bridged Mesoporous Organosilica Nanomedicine for Precise Treatment of Acute Pancreatitis.

Wang Y, Qian D, Wang X, Zhang X, Li Z, Meng X, Yu L, Yan X, He Z
ACS nano 2024 Jul 23;18(29):19283-19302

Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.

Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701

Exploring the inhibitory impact of Mongolian medicinal He-Zi-3 soup on mammary gland hyperplasia in rats induced by estrogen and progestogen.

Liang C, Mu X, Bao Q, Borzigin P, Sheng H, Han X, Chen Y, Wang T
Journal of ethnopharmacology 2024 Jul 15;329:117854

Construction of a dual-component hydrogel matrix for 3D biomimetic skin based on photo-crosslinked chondroitin sulfate/collagen.

He S, Li H, Chi B, Zhang X, Wang Y, Wu J, Huang Q
International journal of biological macromolecules 2024 Jan;254(Pt 3):127940

Astragalus saponins protect against extrahepatic and intrahepatic cholestatic liver fibrosis models by activation of farnesoid X receptor.

Zhang L, Shi J, Shen Q, Fu Y, Qi S, Wu J, Chen J, Zhang H, Mu Y, Chen G, Liu P, Liu W
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116833

UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis.

Fan M, Huo S, Guo Y, Wang R, Hao W, Zhang Z, Wang L, Zhao Y
Cell reports 2024 Feb 27;43(2):113808

Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.

Duan S, Li X, Han J, Yang Y, Luo R, Cai Y, Li X, Zheng Q, Guo J, Liu R
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)

S-Nitrosylation of NOTCH1 Regulates Mesenchymal Stem Cells Differentiation Into Hepatocyte-Like Cells by Inhibiting Notch Signalling Pathway.

Wang X, Xu Y, Wang Y, Tang X, Zhou X, Lu W, Chen W, Li L, Zhou L, Ye J
Journal of cellular and molecular medicine 2024 Dec;28(23):e70274

Establishment and characterization of a highly metastatic hepatocellular carcinoma cell line.

Huang J, Sun M, Wang M, Yu A, Zheng H, Bu C, Zhou J, Zhang Y, Qiao Y, Hu Z
Bioengineered 2024 Dec;15(1):2296775

Hypocrellin A against intrahepatic Cholangiocarcinoma via multi-target inhibition of the PI3K-AKT-mTOR, MAPK, and STAT3 signaling pathways.

Chen B, Chen Q, Lu M, Zou E, Lin G, Yao J, Wang L, Gan Y, Chen B, Chen G, Wu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156022

Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer.

Wang X, Liu X, Xiao R, Fang Y, Zhou F, Gu M, Luo X, Jiang D, Tang Y, You L, Zhao Y
Cancer letters 2024 Aug 28;598:217117

Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.

Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15

Fibroblast growth factor 1 ameliorates thin endometrium in rats through activation of the autophagic pathway.

Zhu J, Li Z, Yin F, Yu X, Lu Y, Zhou T, Gong F, Xu Z
Frontiers in pharmacology 2023;14:1143096

Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway.

Wang XJ, Zhang D, Yang YT, Li XY, Li HN, Zhang XP, Long JY, Lu YQ, Liu L, Yang G, Liu J, Hong J, Wu HG, Ma XP
Frontiers in immunology 2023;14:1089809

Babao Dan decreases hepatocarcinogenesis by inhibiting hepatic progenitor cells malignant transformation via down-regulating toll-like receptor 4.

Liang L, Zhang LY, Liu WT, Zong C, Gao L, Li R, Zhao QD, Zhao NP, Wei LX, Zhang L, Han ZP
Frontiers in oncology 2023;13:1073859

Long non coding RNA, C8orf49, a novel diagnostic and prognostic biomarker, enhances PTEN/FZD4-mediated cell growth and metastasis by sponging miR-1323 in endometriosis.

Yin M, Wang J, Ying X, Fang Z, Zhang X
Molecular and cellular endocrinology 2023 Sep 15;575:112040

The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium.

Shu Z, Fan M, Tu B, Tang Z, Wang H, Li H, Li H, Yuan M, Bai J, Huo S, Wang L, Zhu WG, Wang W, Liu X, Shu S, Zhao Y
Nature communications 2023 Oct 28;14(1):6885

Tumor Microenvironment Responsive CD8(+) T Cells and Myeloid-Derived Suppressor Cells to Trigger CD73 Inhibitor AB680-Based Synergistic Therapy for Pancreatic Cancer.

Chen Q, Yin H, He J, Xie Y, Wang W, Xu H, Zhang L, Shi C, Yu J, Wu W, Liu L, Pu N, Lou W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302498

An optimized visualization and quantitative protocol for in-depth evaluation of lymphatic vessel architecture in the liver.

Jeong J, Tanaka M, Yang Y, Arefyev N, DiRito J, Tietjen G, Zhang X, McConnell MJ, Utsumi T, Iwakiri Y
American journal of physiology. Gastrointestinal and liver physiology 2023 Nov 1;325(5):G379-G390

Yes-associated protein promotes the proliferation and differentiation of liver progenitor cells during liver fibrosis.

Shen Z, Dai W, Guo Y, Wang J, Shen B, Li B, Lu L, Cai X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22916

Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling.

Zheng Y, Wang N, Wang S, Zhang J, Yang B, Wang Z
Journal of experimental & clinical cancer research : CR 2023 May 20;42(1):129

Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment.

Xi J, Pan Y, Jin C, Liu J, Cheng J, Xu B
Experimental animals 2023 May 17;72(2):274-284

The combination of gemcitabine and ginsenoside Rh2 enhances the immune function of dendritic cells against pancreatic cancer via the CARD9-BCL10-MALT1 / NF-κB pathway.

Li Q, He J, Li S, Tian C, Yang J, Yuan H, Lu Y, Fagone P, Nicoletti F, Xiang M
Clinical immunology (Orlando, Fla.) 2023 Mar;248:109217

BM-MSCs overexpressing the Numb enhance the therapeutic effect on cholestatic liver fibrosis by inhibiting the ductular reaction.

Xu YN, Xu W, Zhang X, Wang DY, Zheng XR, Liu W, Chen JM, Chen GF, Liu CH, Liu P, Mu YP
Stem cell research & therapy 2023 Mar 20;14(1):45

Study of hydrosalpinx on endometrial growth and expression of HOXA10mRNA and related factors.

Li T, Lu F, Wu C, Cai YL, Yang L, Cai H
Heliyon 2023 Jun;9(6):e17063

Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.

Liu X, Zhuang Y, Huang W, Wu Z, Chen Y, Shan Q, Zhang Y, Wu Z, Ding X, Qiu Z, Cui W, Wang Z
Nature communications 2023 Jul 11;14(1):4106

Efficient establishment of an optimized culture condition for cashmere goat primary hair follicle stem cells.

Li Y, Jin M, Gao Y, Lu L, Cao J, Liu Y, Chen Y, Wang X
Journal of animal science 2023 Jan 3;101

Semaglutide reduces tumor burden in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH-HCC with advanced fibrosis.

Hansen HH, Pors S, Andersen MW, Vyberg M, Nøhr-Meldgaard J, Nielsen MH, Oró D, Madsen MR, Lewinska M, Møllerhøj MB, Madsen AN, Feigh M
Scientific reports 2023 Dec 27;13(1):23056

Loss of α-1,2-mannosidase MAN1C1 promotes tumorigenesis of intrahepatic cholangiocarcinoma through enhancing CD133-FIP200 interaction.

Wei Y, Chen Q, Chen J, Zhou C, Geng S, Shi D, Huang S, Liang Z, Chen X, Ren N, Jiang J
Cell reports 2023 Dec 26;42(12):113588

Kartogenin-loaded hydrogel promotes intervertebral disc repair via protecting MSCs against reactive oxygen species microenvironment by Nrf2/TXNIP/NLRP3 axis.

Wang F, Guo K, Nan L, Wang S, Lu J, Wang Q, Ba Z, Huang Y, Wu D
Free radical biology & medicine 2023 Aug 1;204:128-150

Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications.

Martin-Serrano MA, Kepecs B, Torres-Martin M, Bramel ER, Haber PK, Merritt E, Rialdi A, Param NJ, Maeda M, Lindblad KE, Carter JK, Barcena-Varela M, Mazzaferro V, Schwartz M, Affo S, Schwabe RF, Villanueva A, Guccione E, Friedman SL, Lujambio A, Tocheva A, Llovet JM, Thung SN, Tsankov AM, Sia D
Gut 2023 Apr;72(4):736-748

A Novel Combination of Keratinocyte and Autologous Microskin Grafting to Repair Full-Thickness Skin Loss.

Yin K, Li D, Shen C, Shang Y, Li L, Zhao D, Cheng W
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 2022;63(4):269-277

Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.

Li J, Zhao B, Dai Y, Zhang X, Chen Y, Wu X
Oxidative medicine and cellular longevity 2022;2022:9042345

Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.

Wang Y, Wang H, Zhuo Y, Hu Y, Li X, Xu Y, Sun B, Liu M, Zou L, Liu L, Luo L, Zhao C, Li P, Zhou Q
International journal of biological sciences 2022;18(9):3676-3696

Sex-, age-, and organ-dependent improvement of bile acid hydrophobicity by ursodeoxycholic acid treatment: A study using a mouse model with human-like bile acid composition.

Ueda H, Honda A, Miyazaki T, Morishita Y, Hirayama T, Iwamoto J, Nakamoto N, Ikegami T
PloS one 2022;17(7):e0271308

p70 Ribosomal Protein S6 Kinase Is a Checkpoint of Human Hepatic Stellate Cell Activation and Liver Fibrosis in Mice.

Reiter FP, Ye L, Ofner A, Schiergens TS, Ziesch A, Brandl L, Ben Khaled N, Hohenester S, Wimmer R, Artmann R, He Y, Lee SML, Mayr D, Zhang C, Gerbes AL, Mayerle J, Denk G, De Toni EN
Cellular and molecular gastroenterology and hepatology 2022;13(1):95-112

Astragalus saponins and its main constituents ameliorate ductular reaction and liver fibrosis in a mouse model of DDC-induced cholestatic liver disease.

Zhang L, Hu Y, Qi S, Zhang C, Zhou Q, Zhang D, Mu Y, Zhang H, Chen G, Liu P, Chen J, Liu W
Frontiers in pharmacology 2022;13:965914

AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages.

Xia L, Zhang C, Lv N, Liang Z, Ma T, Cheng H, Xia Y, Shi L
Theranostics 2022;12(6):2928-2947

Establishment and characterization of an immortalized epithelial cell line from human gallbladder.

Wang Z, Wang S, Jia Z, Zhao Y, Yang M, Yan W, Chen T, Xiang D, Shao R, Liu Y
Frontiers in oncology 2022;12:994087

Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.

Bai F, Duan J, Yang D, Lai X, Zhu X, He X, Hu A
Stem cell research & therapy 2022 Sep 8;13(1):468

[Overexpression of Numb gene can inhibit the progression of biliary liver fibrosis in adult liver].

Xu YN, Xu W, Chen JM, Liu W, Chen GF, Zhang H, Liu P, Mu YP
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2022 Nov 20;30(11):1175-1181

SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.

Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969

Eicosapentaenoic acid mitigates palmitic acid-induced heat shock response, inflammation and repair processes in fish intestine.

Shi P, Liao K, Xu J, Wang Y, Xu S, Yan X
Fish & shellfish immunology 2022 May;124:362-371

Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation.

Nie L, Zhang LX, Wang YC, Long Y, Ma YD, Liao LC, Dai XH, Cui ZH, Liu H, Wang ZQ, Ma ZY, Yuan DZ, Yue LM
Reproduction (Cambridge, England) 2022 Mar 30;163(5):293-307

Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer.

Jiang SH, Liu D, Hu LP, Zhang S, Yu Y, Sun YW, Ji J, Zhang ZG
EBioMedicine 2022 Jun;80:104050

Neutralizing Antibodies to Human Cytomegalovirus Recombinant Proteins Reduce Infection in an Ex Vivo Model of Developing Human Placentas.

Tabata T, Petitt M, Li J, Chi X, Chen W, Yurgelonis I, Wellnitz S, Bredl S, Vicente T, Yang X, Dormitzer PR, Pereira L
Vaccines 2022 Jul 4;10(7)

Glycolysis addiction compensating for a defective pentose phosphate pathway confers gemcitabine sensitivity in SETD2-deficient pancreatic cancer.

Shen X, Chen Y, Liu M, Shi J, Tang Y, Yang X, Xu D, Yao H, Lu P, Sun Y, Xue J, Niu N
Biochemical and biophysical research communications 2022 Jul 30;615:9-16

The presence of living endometrial cells in ovarian endometriotic cyst fluid may contribute to the recurrence of endometriosis after surgical excision of endometriomas.

Xu X, Chen Y, Yu Q, Wang J, Xu P, Zhu L, Xu Q, Zhang J, Cui S, Yu K, Li T, Guo X, Zhang X
Journal of ovarian research 2022 Jul 30;15(1):89

SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.

He R, Shi J, Xu D, Yang J, Shen Y, Jiang YS, Tao L, Yang M, Fu X, Yang JY, Liu D, Huo Y, Shen X, Lu P, Niu N, Sun YW, Xue J, Liu W
Cancer letters 2022 Jul 10;538:215693

Berberine inhibits pancreatic intraepithelial neoplasia by inhibiting glycolysis via the adenosine monophosphate -activated protein kinase pathway.

Liu M, Yang Y, Kang W, Liu Y, Tao X, Li X, Pan Y
European journal of pharmacology 2022 Jan 15;915:174680

Comparative study of the external auditory canal in humans and large mammals.

Wang J, He A, Yin D, Zhu Y, Zhou G, Zhang T
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):436-445

YAP affects the efficacy of liver progenitor cells transplantation in CCl(4)-induced acute liver injury.

Dai W, Shen Z, Guo Y, Wang J, Li X, Wang J, Lu L, Cai X, Li Y
Biochemical and biophysical research communications 2022 Dec 17;634:129-137

Isolation, culture, and identification of ceruminous gland cells.

Wang J, He A, Zhu Y, Zhou G, Zhang T
Journal of molecular histology 2022 Apr;53(2):227-237

CD44 expression in the bile duct epithelium is related to hepatic fibrosis in nonalcoholic steatohepatitis rats induced by a choline-deficient, methionine-lowered, L-amino acid diet.

Uno K, Miyajima K, Toma M, Suzuki-Kemuriyama N, Nakae D
Journal of toxicologic pathology 2022 Apr;35(2):149-157

Sperm acquire epididymis-derived proteins through epididymosomes.

Barrachina F, Battistone MA, Castillo J, Mallofré C, Jodar M, Breton S, Oliva R
Human reproduction (Oxford, England) 2022 Apr 1;37(4):651-668

Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.

Li Q, Gong Y, Wang Y, Liu B, Chu Y, Gui S, Zheng Y, Chen X
Frontiers in nutrition 2021;8:791861

A Simulation Study on the Growth of Oviduct Mucosa Cells in the Uterine Cavity Microenvironment.

Wu CR, Cai HL, Cai DX, Li TL, Shen R, Zi D
International journal of women's health 2021;13:829-840

Prognostic significance of KRT19 in Lung Squamous Cancer.

Yuan X, Yi M, Dong B, Chu Q, Wu K
Journal of Cancer 2021;12(4):1240-1248

The combined induction of liver progenitor cells and the suppression of stellate cells by small molecules reverts chronic hepatic dysfunction.

Huang WJ, Zhou X, Fu GB, Ding M, Wu HP, Zeng M, Zhang HD, Xu LY, Gao Y, Wang HY, Yan HX
Theranostics 2021;11(11):5539-5552

IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.

Cheng S, Lv R, Xu J, Hirman AR, Du L
The Journal of surgical research 2021 Sep;265:100-113

Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1-mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation.

Zhu X, Ye S, Yu D, Zhang Y, Li J, Zhang M, Leng Y, Yang T, Luo J, Chen X, Zhang H, Kong L
British journal of pharmacology 2021 Sep;178(17):3428-3447

Expression of SGLT1 in the Mouse Endometrial Epithelium and its Role in Early Embryonic Development and Implantation.

Zhang LX, Song JW, Ma YD, Wang YC, Cui ZH, Long Y, Yuan DZ, Zhang JH, Hu Y, Yu LL, Nie L, Yue LM
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3094-3108

The distinct responsiveness of cytokeratin 19-positive hepatocellular carcinoma to regorafenib.

Zhuo J, Lu D, Lin Z, Yang X, Yang M, Wang J, Tao Y, Wen X, Li H, Lian Z, Cen B, Dong S, Wei X, Xie H, Zheng S, Shen Y, Xu X
Cell death & disease 2021 Nov 16;12(12):1084

Liver injury after small bowel resection is prevented in obesity-resistant 129S1/SvImJ mice.

Onufer EJ, Han YH, Courtney C, Steinberger A, Tecos M, Sutton S, Sescleifer A, Ou J, Sanguinetti Czepielewski R, Randolph GJ, Warner BW
American journal of physiology. Gastrointestinal and liver physiology 2021 May 1;320(5):G907-G918

PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer.

Jiang TY, Feng XF, Fang Z, Cui XW, Lin YK, Pan YF, Yang C, Ding ZW, Zhang YJ, Tan YX, Wang HY, Dong LW
Cancer letters 2021 Mar 31;501:187-199

ODAM promotes junctional epithelium-related gene expression via activation of WNT1 signaling pathway in an ameloblast-like cell line ALC.

Song D, Yang S, Tan T, Wang R, Ma Z, Wang Y, Wang L
Journal of periodontal research 2021 Jun;56(3):482-491

Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.

Yang G, Guan W, Cao Z, Guo W, Xiong G, Zhao F, Feng M, Qiu J, Liu Y, Zhang MQ, You L, Zhang T, Zhao Y, Gu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jun 15;27(12):3383-3396

The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation.

Shao C, Yang X, Jing Y, Hou X, Huang Y, Zong C, Gao L, Liu W, Jiang J, Ye F, Shi J, Zhao Q, Li R, Zhang X, Wei L
Stem cell research & therapy 2021 Jun 10;12(1):342

Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.

Lin Z, Zhao C, Lei Z, Zhang Y, Huang R, Lin B, Dong Y, Zhang H, Li J, Li X
Stem cell research & therapy 2021 Jun 10;12(1):341

Rebalancing TGF-β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis.

Yang Y, Sun M, Li W, Liu C, Jiang Z, Gu P, Li J, Wang W, You R, Ba Q, Li X, Wang H
Clinical and translational medicine 2021 Jul;11(7):e410

Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.

Xu Y, Xu W, Liu W, Chen G, Jiang S, Chen J, Jian X, Zhang H, Liu P, Mu Y
Pharmaceutical biology 2021 Dec;59(1):1150-1160

β-blocker eye drops affect ocular surface through β2 adrenoceptor of corneal limbal stem cells.

Yuan X, Ma X, Yang L, Zhou Q, Li Y
BMC ophthalmology 2021 Dec 5;21(1):419

ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.

Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H
Nature communications 2021 Aug 11;12(1):4867

Erzhu Jiedu decoction ameliorates liver precancerous lesions in a rat model of liver cancer.

Cheng Y, Chen T, Chen J
Journal of Cancer 2020;11(24):7302-7311

Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer.

Wang Q, Li M, Gan Y, Jiang S, Qiao J, Zhang W, Fan Y, Shen Y, Song Y, Meng Z, Yao M, Gu J, Zhang Z, Tu H
Theranostics 2020;10(5):2141-2157

Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer.

Xiong X, Rao G, Roy RV, Zhang Y, Means N, Dey A, Tsaliki M, Saha S, Bhattacharyya S, Dhar Dwivedi SK, Rao CV, McCormick DJ, Dhanasekaran D, Ding K, Gillies E, Zhang M, Yang D, Bhattacharya R, Mukherjee P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12024-12039

PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.

Jiang TY, Pan YF, Wan ZH, Lin YK, Zhu B, Yuan ZG, Ma YH, Shi YY, Zeng TM, Dong LW, Tan YX, Wang HY
Science translational medicine 2020 Sep 23;12(562)

Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis.

Xu W, Xu YN, Zhang X, Xu Y, Jian X, Chen JM, Chen GF, Zhang H, Liu P, Mu YP
Scientific reports 2020 Oct 15;10(1):17486

XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.

Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, Lin Y, Wang Z
Cell communication and signaling : CCS 2020 Mar 26;18(1):48

Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin-ɑvβ6 integrin in liver fibrosis.

Xu T, Lu Z, Xiao Z, Liu F, Chen Y, Wang Z, Zhu S, Song Y
Cell death & disease 2020 Mar 23;11(3):199

Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice.

Yang P, Wang Y, Tang W, Sun W, Ma Y, Lin S, Jing J, Jiang L, Shi H, Song Z, Yu L
Scientific reports 2020 Mar 13;10(1):4701

Heme oxygenase-1-modified bone marrow mesenchymal stem cells combined with normothermic machine perfusion to protect donation after circulatory death liver grafts.

Cao H, Yang L, Hou B, Sun D, Lin L, Song HL, Shen ZY
Stem cell research & therapy 2020 Jun 5;11(1):218

The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.

Xu F, Shen X, Sun C, Xu X, Wang W, Zheng J
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 2;26:e920670

Generation of liver bipotential organoids with a small-molecule cocktail.

Wang X, Ni C, Jiang N, Wei J, Liang J, Zhao B, Lin X
Journal of molecular cell biology 2020 Aug 1;12(8):618-629

Human Adipose-Derived Stem Cells Promote Seawater-Immersed Wound Healing by Activating Skin Stem Cells via the EGFR/MEK/ERK Pathway.

Xiong J, Ji B, Wang L, Yan Y, Liu Z, Fang S, Wu M, Wang Y, Song J
Stem cells international 2019;2019:7135974

Cytoplasmic SIRT1 inhibits cell migration and invasion by impeding epithelial-mesenchymal transition in ovarian carcinoma.

Yang T, Zhou R, Yu S, Yu S, Cui Z, Hu P, Liu J, Qiao Q, Zhang J
Molecular and cellular biochemistry 2019 Sep;459(1-2):157-169

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas.

Tabata T, Petitt M, Fang-Hoover J, Freed DC, Li F, An Z, Wang D, Fu TM, Pereira L
Vaccines 2019 Sep 29;7(4)

Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures.

Ruiz García S, Deprez M, Lebrigand K, Cavard A, Paquet A, Arguel MJ, Magnone V, Truchi M, Caballero I, Leroy S, Marquette CH, Marcet B, Barbry P, Zaragosi LE
Development (Cambridge, England) 2019 Oct 23;146(20)

Periodic Oxaliplatin Administration in Synergy with PER2-Mediated PCNA Transcription Repression Promotes Chronochemotherapeutic Efficacy of OSCC.

Tang Q, Xie M, Yu S, Zhou X, Xie Y, Chen G, Guo F, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Nov 6;6(21):1900667

THZ1 reveals CDK7-dependent transcriptional addictions in pancreatic cancer.

Lu P, Geng J, Zhang L, Wang Y, Niu N, Fang Y, Liu F, Shi J, Zhang ZG, Sun YW, Wang LW, Tang Y, Xue J
Oncogene 2019 May;38(20):3932-3945

Cytokeratin expression in epidermal stem cells in skin adnexal tumors.

Zhou X, Li G, Wang D, Sun X, Li X
Oncology letters 2019 Jan;17(1):927-932

Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells.

Shi Y, Zhou D, Wang B, Zhou D, Shi B
International journal of molecular medicine 2019 Feb;43(2):1021-1032

Diet-induced hepatic steatosis activates Ras to promote hepatocarcinogenesis via CPT1α.

Xu A, Wang B, Fu J, Qin W, Yu T, Yang Z, Lu Q, Chen J, Chen Y, Wang H
Cancer letters 2019 Feb 1;442:40-52

A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal.

Tu Q, Yang D, Zhang X, Jia X, An S, Yan L, Dai H, Ma Y, Tang C, Tong W, Hou Z, Lv L, Tan J, Zhao X
Disease models & mechanisms 2019 Apr 15;12(4)

Progesterone-induced miR-152 interferes with embryonic implantation by downregulating GLUT3 in endometrial epithelium.

Nie L, Zhao YB, Zhao D, Long Y, Lei Y, Liu M, Wang YC, Zhang XQ, Zhang JH, Yuan DZ, Yue LM
American journal of physiology. Endocrinology and metabolism 2019 Apr 1;316(4):E557-E567

Effects of Neuropeptide Substance P on Proliferation and β-Cell Differentiation of Adult Pancreatic Ductal Cells.

Zhang N, Gao D, Liu Y, Ji S, Sha L
Frontiers in neuroscience 2018;12:806

Effects of human amnion-derived mesenchymal stem cells and conditioned medium in rats with sclerosing cholangitis.

Sugiura R, Ohnishi S, Ohara M, Ishikawa M, Miyamoto S, Onishi R, Yamamoto K, Kawakubo K, Kuwatani M, Sakamoto N
American journal of translational research 2018;10(7):2102-2114

Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars.

Gu Z, Li Y, Li H
JAMA facial plastic surgery 2018 Mar 1;20(2):128-135

Osteoprotegerin deficiency causes morphological and quantitative damage in epithelial rests of Malassez.

Wang Y, Liu M, Deng S, Sui X, Fan L, Zhang Q
Journal of molecular histology 2018 Jun;49(3):329-338

Cd271 mediates proliferation and differentiation of epidermal stem cells to support cutaneous burn wound healing.

Zhang M, Cao Y, Li X, Hu L, Taieb SK, Zhu X, Zhang J, Feng Y, Zhao R, Wang M, Xue W, Yang Z, Wang Y
Cell and tissue research 2018 Feb;371(2):273-282

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells.

Rahn S, Zimmermann V, Viol F, Knaack H, Stemmer K, Peters L, Lenk L, Ungefroren H, Saur D, Schäfer H, Helm O, Sebens S
Cancer letters 2018 Feb 28;415:129-150

Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.

Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390

Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells.

Jeng KS, Jeng CJ, Jeng WJ, Sheen IS, Li SY, Lu SJ, Chang CF
American journal of surgery 2018 Apr;215(4):735-743

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma.

Lenk L, Pein M, Will O, Gomez B, Viol F, Hauser C, Egberts JH, Gundlach JP, Helm O, Tiwari S, Weiskirchen R, Rose-John S, Röcken C, Mikulits W, Wenzel P, Schneider G, Saur D, Schäfer H, Sebens S
Oncoimmunology 2017;7(1):e1368603

Gypenosides Ameliorate Carbon Tetrachloride-Induced Liver Fibrosis by Inhibiting the Differentiation of Hepatic Progenitor Cells into Myofibroblasts.

Chen J, Li X, Hu Y, Liu W, Zhou Q, Zhang H, Mu Y, Liu P
The American journal of Chinese medicine 2017;45(5):1061-1074

Huang Qi Decoction Prevents BDL-Induced Liver Fibrosis Through Inhibition of Notch Signaling Activation.

Zhang X, Xu Y, Chen JM, Liu C, Du GL, Zhang H, Chen GF, Jiang SL, Liu CH, Mu YP, Liu P
The American journal of Chinese medicine 2017;45(1):85-104

N-Cadherin Maintains the Healthy Biology of Nucleus Pulposus Cells under High-Magnitude Compression.

Wang Z, Leng J, Zhao Y, Yu D, Xu F, Song Q, Qu Z, Zhuang X, Liu Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(6):2327-2337

Maintaining viability and characteristics of cholangiocarcinoma tissue by vitrification-based cryopreservation.

Zeng M, Yang QR, Fu GB, Zhang Y, Zhou X, Huang WJ, Zhang HD, Li WJ, Wang ZY, Yan HX, Zhai B
Cryobiology 2017 Oct;78:41-46

Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats.

Yan J, Xie G, Liang C, Hu Y, Zhao A, Huang F, Hu P, Liu P, Jia W, Wang X
Scientific reports 2017 Jun 23;7(1):4211

PRL-3 Is Involved in Estrogen- and IL-6-Induced Migration of Endometrial Stromal Cells From Ectopic Endometrium.

Ren S, Zhou Y, Fang X, She X, Wu Y, Wu X
Reproductive sciences (Thousand Oaks, Calif.) 2017 Jan;24(1):124-132

Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta.

Tabata T, Petitt M, Fang-Hoover J, Zydek M, Pereira L
The American journal of pathology 2016 Nov;186(11):2970-2986

Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes.

Zhang X, Du G, Xu Y, Li X, Fan W, Chen J, Liu C, Chen G, Liu C, Zern MA, Mu Y, Liu P
Laboratory investigation; a journal of technical methods and pathology 2016 Mar;96(3):350-60

Liver epithelial cells inhibit proliferation and invasiveness of hepatoma cells.

Jeng KS, Jeng CJ, Jeng WJ, Sheen IS, Li SY, Hung ZH, Hsiau HI, Yu MC, Chang CF
Oncology reports 2016 Mar;35(3):1622-8

DJ-1 deficiency attenuates expansion of liver progenitor cells through modulating the inflammatory and fibrogenic niches.

Chen L, Luo M, Sun X, Qin J, Yu C, Wen Y, Zhang Q, Gu J, Xia Q, Kong X
Cell death & disease 2016 Jun 9;7(6):e2257

EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop.

Yang CF, Yang GD, Huang TJ, Li R, Chu QQ, Xu L, Wang MS, Cai MD, Zhong L, Wei HJ, Huang HB, Huang JL, Qian CN, Huang BJ
Oncogene 2016 Jun 30;35(26):3419-31

c-Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma.

You L, Ren X, Du Y, Zhao W, Cui M, Chen G, Zhao Y
Oncology reports 2016 Dec;36(6):3413-3420

Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission.

Tabata T, Petitt M, Puerta-Guardo H, Michlmayr D, Wang C, Fang-Hoover J, Harris E, Pereira L
Cell host & microbe 2016 Aug 10;20(2):155-66

Actin-like 6A predicts poor prognosis of hepatocellular carcinoma and promotes metastasis and epithelial-mesenchymal transition.

Xiao S, Chang RM, Yang MY, Lei X, Liu X, Gao WB, Xiao JL, Yang LY
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1256-71

Defective Initiation of Liver Regeneration in Osteopontin-Deficient Mice after Partial Hepatectomy due to Insufficient Activation of IL-6/Stat3 Pathway.

Wen Y, Feng D, Wu H, Liu W, Li H, Wang F, Xia Q, Gao WQ, Kong X
International journal of biological sciences 2015;11(10):1236-47

Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway.

Chen J, Zhang X, Xu Y, Li X, Ren S, Zhou Y, Duan Y, Zern M, Zhang H, Chen G, Liu C, Mu Y, Liu P
PloS one 2015;10(6):e0130310

Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development.

Assouline-Thomas B, Ellis D, Petropavlovskaia M, Makhlin J, Ding J, Rosenberg L
Differentiation; research in biological diversity 2015 Nov-Dec;90(4-5):77-90

CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB.

Kim KH, Chen CC, Alpini G, Lau LF
The Journal of clinical investigation 2015 May;125(5):1886-900

Astragaloside prevents BDL-induced liver fibrosis through inhibition of notch signaling activation.

Yongping M, Zhang X, Xuewei L, Fan W, Chen J, Zhang H, Chen G, Liu C, Liu P
Journal of ethnopharmacology 2015 Jul 1;169:200-9

Reg3g Promotes Pancreatic Carcinogenesis in a Murine Model of Chronic Pancreatitis.

Yin G, Du J, Cao H, Liu X, Xu Q, Xiang M
Digestive diseases and sciences 2015 Dec;60(12):3656-68

Hepatocyte growth factor gene-modified adipose-derived mesenchymal stem cells ameliorate radiation induced liver damage in a rat model.

Zhang J, Zhou S, Zhou Y, Feng F, Wang Q, Zhu X, Ai H, Huang X, Zhang X
PloS one 2014;9(12):e114670

Epiregulin promotes the emergence and proliferation of adult liver progenitor cells.

Tomita K, Haga H, Mizuno K, Katsumi T, Sato C, Okumoto K, Nishise Y, Watanabe H, Saito T, Ueno Y
American journal of physiology. Gastrointestinal and liver physiology 2014 Jul 1;307(1):G50-7

Increased expression levels of E-cadherin, cytokeratin 18 and 19 observed in preeclampsia were not correlated with disease severity.

Li XL, Dong X, Xue Y, Li CF, Gou WL, Chen Q
Placenta 2014 Aug;35(8):625-31

Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis.

Wang Z, Liu F, Tu W, Chang Y, Yao J, Wu W, Jiang X, He X, Lin J, Song Y
Journal of cellular and molecular medicine 2012 Jan;16(1):118-28

Epidermal growth factor induces adult human islet cell dedifferentiation.

Hanley SC, Assouline-Thomas B, Makhlin J, Rosenberg L
The Journal of endocrinology 2011 Dec;211(3):231-9

PCDH24-induced contact inhibition involves downregulation of beta-catenin signaling.

Ose R, Yanagawa T, Ikeda S, Ohara O, Koga H
Molecular oncology 2009 Feb;3(1):54-66

Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity.

Martin-Pagola A, Sisino G, Allende G, Dominguez-Bendala J, Gianani R, Reijonen H, Nepom GT, Ricordi C, Ruiz P, Sageshima J, Ciancio G, Burke GW, Pugliese A
Diabetologia 2008 Oct;51(10):1803-13

Characterization of pancreatic ductal cells in human islet preparations.

Ichii H, Miki A, Yamamoto T, Molano RD, Barker S, Mita A, Rodriguez-Diaz R, Klein D, Pastori R, Alejandro R, Inverardi L, Pileggi A, Ricordi C
Laboratory investigation; a journal of technical methods and pathology 2008 Nov;88(11):1167-77

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: A431 cells were subjected to SDS PAGE followed by western blot with 10712-1-AP(KRT19 antibody) at dilution of 1:1500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human prostate cancer using 10712-1-AP(KRT19 antibody) at dilution of 1:100 (under 25x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Cytokeratin 19 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cytokeratin 19. This antibody recognizes human, mouse antigen. The Cytokeratin 19 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
Appendix: 10712-1-AP.pdf

: Show more