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- Antibody Data
- Antigen structure
- References [23]
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- Product number
- 19124-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19124-1-AP, RRID:AB_10642143
- Product name
- TRPA1 antibody
- Antibody type
- Polyclonal
- Description
- TRPA1 antibody (Cat. #19124-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references High humidity and NO(2) co-exposure exacerbates allergic asthma by increasing oxidative stress, inflammatory and TRP protein expressions in lung tissue.
Ligustilide covalently binds to Cys703 in the pre-S1 helix of TRPA1, blocking the opening of channel and relieving pain in rats with acute soft tissue injury.
Zhisou powder suppresses airway inflammation in LPS and CS-induced post-infectious cough model mice via TRPA1/TRPV1 channels.
Role of TRPV1 and TRPA1 in TSLP production in nasal epithelial cells.
Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes.
Aconitine - A promising candidate for treating cold and mechanical allodynia in cancer induced bone pain.
L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway.
Dissecting the effect of ileal faecal diversion on the intestine using single-cell sequencing.
Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma through the TRPA1-p38 MAPK pathway.
Water extract of Notopterygium incisum alleviates cold allodynia in neuropathic pain by regulation of TRPA1.
The Effectiveness of Wogonin on Treating Cough Mice With Mycoplasma Pneumoniae Infection.
Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain.
UVR Promotes Keratinocyte Phagocytosis and Skin Pigmentation Through TRPA1 Channels.
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK/AKT Signaling Pathway.
Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.
Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts.
Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells.
Menthol from Mentha piperita Suppresses the Milk Production of Lactating Mammary Epithelial Cells In Vivo and In Vitro.
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Transient receptor potential ankyrin 1 (TRPA1) positively regulates imiquimod-induced, psoriasiform dermal inflammation in mice.
Lu C, Liu Q, Qiao Z, Yang X, Baghani AN, Wang F
Environmental pollution (Barking, Essex : 1987) 2024 Jul 15;353:124127
Environmental pollution (Barking, Essex : 1987) 2024 Jul 15;353:124127
Ligustilide covalently binds to Cys703 in the pre-S1 helix of TRPA1, blocking the opening of channel and relieving pain in rats with acute soft tissue injury.
Zhang K, Liu W, Shen F, Luan G, Han Y, Xu J, Fu C, Wu W, Hou Y, Jiang M, Zhang T, Bai G
Journal of ethnopharmacology 2024 Aug 10;330:118217
Journal of ethnopharmacology 2024 Aug 10;330:118217
Zhisou powder suppresses airway inflammation in LPS and CS-induced post-infectious cough model mice via TRPA1/TRPV1 channels.
Xu Y, Cao S, Wang SF, Ma W, Gou XJ
Journal of ethnopharmacology 2024 Apr 24;324:117741
Journal of ethnopharmacology 2024 Apr 24;324:117741
Role of TRPV1 and TRPA1 in TSLP production in nasal epithelial cells.
Li J, Wang F, Meng C, Zhu D
International immunopharmacology 2024 Apr 20;131:111916
International immunopharmacology 2024 Apr 20;131:111916
Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes.
Lee HJ, Alirzayeva H, Koyuncu S, Rueber A, Noormohammadi A, Vilchez D
Nature aging 2023 May;3(5):546-566
Nature aging 2023 May;3(5):546-566
Aconitine - A promising candidate for treating cold and mechanical allodynia in cancer induced bone pain.
Jin X, Cheng J, Zhang Q, Ji H, Zhu C, Yang Y, Zhou Y, Yu G, Wang C, Tang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114284
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114284
L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway.
Liao T, Mei W, Zhang L, Ding L, Yang N, Wang P, Zhang L
Journal of orthopaedic surgery and research 2023 May 26;18(1):386
Journal of orthopaedic surgery and research 2023 May 26;18(1):386
Dissecting the effect of ileal faecal diversion on the intestine using single-cell sequencing.
Ma H, Li X, Pan Y, Wang L, Han B, Xie H, Zheng H, Jiang E, Chen J, Li Y, Ji G, Qiu Y, Xiao W
Clinical and translational medicine 2023 Jul;13(7):e1321
Clinical and translational medicine 2023 Jul;13(7):e1321
Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma through the TRPA1-p38 MAPK pathway.
Han Q, Gao X, Wang S, Wei Z, Wang Y, Xu K, Chen M
Toxicology letters 2023 Aug 1;384:73-85
Toxicology letters 2023 Aug 1;384:73-85
Water extract of Notopterygium incisum alleviates cold allodynia in neuropathic pain by regulation of TRPA1.
Ruan Y, Jin X, Ji H, Zhu C, Yang Y, Zhou Y, Yu G, Wang C, Tang Z
Journal of ethnopharmacology 2023 Apr 6;305:116065
Journal of ethnopharmacology 2023 Apr 6;305:116065
The Effectiveness of Wogonin on Treating Cough Mice With Mycoplasma Pneumoniae Infection.
Liang M, Meng Y, Wang X, Wang L, Tang G, Wang W
Frontiers in molecular biosciences 2022;9:803842
Frontiers in molecular biosciences 2022;9:803842
Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain.
Xie AX, Iguchi N, Clarkson TC, Malykhina AP
PloS one 2022;17(1):e0262769
PloS one 2022;17(1):e0262769
UVR Promotes Keratinocyte Phagocytosis and Skin Pigmentation Through TRPA1 Channels.
Liu Y, Li Z, Wu W, Wang Y, Zhao G, Liu Y, Liu J, Song Z
Clinical, cosmetic and investigational dermatology 2022;15:1183-1193
Clinical, cosmetic and investigational dermatology 2022;15:1183-1193
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N
Frontiers in aging neuroscience 2022;14:1075161
Frontiers in aging neuroscience 2022;14:1075161
Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK/AKT Signaling Pathway.
Yang XJ, Ling S, Zhou ML, Deng HJ, Qi M, Liu XL, Zhen C, Chen YX, Fan XR, Wu ZY, Ma FC, Rong J, Di GF, Jiang XC
Neuroscience 2022 Jul 1;494:51-68
Neuroscience 2022 Jul 1;494:51-68
Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.
Hui G, Yang LI, Lei F, Yujie X, Lizhong H, Dan M, Hui Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955
Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
Liu Y, Wang Y, Lou Y, Tian W, Que K
Journal of molecular histology 2021 Oct;52(5):1105-1114
Journal of molecular histology 2021 Oct;52(5):1105-1114
Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts.
Lowin T, Tingting R, Zurmahr J, Classen T, Schneider M, Pongratz G
Cell death & disease 2020 Sep 1;11(8):714
Cell death & disease 2020 Sep 1;11(8):714
Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells.
Yu S, Xin W, Jiang Q, Li A
BioFactors (Oxford, England) 2020 Nov;46(6):934-942
BioFactors (Oxford, England) 2020 Nov;46(6):934-942
Menthol from Mentha piperita Suppresses the Milk Production of Lactating Mammary Epithelial Cells In Vivo and In Vitro.
Suzuki N, Tsugami Y, Wakasa H, Suzuki T, Nishimura T, Kobayashi K
Molecular nutrition & food research 2020 Nov 14;:e2000853
Molecular nutrition & food research 2020 Nov 14;:e2000853
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
Wang Y, Yin S, Mei L, Yang Y, Xu S, He X, Wang M, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2020 May 10;321:71-83
Journal of controlled release : official journal of the Controlled Release Society 2020 May 10;321:71-83
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Liu Z, Wang P, Lu S, Guo R, Gao W, Tong H, Yin Y, Han X, Liu T, Chen X, Zhu MX, Yang Z
Cell calcium 2020 Apr 28;88:102198
Cell calcium 2020 Apr 28;88:102198
Transient receptor potential ankyrin 1 (TRPA1) positively regulates imiquimod-induced, psoriasiform dermal inflammation in mice.
Zhou Y, Han D, Follansbee T, Wu X, Yu S, Wang B, Shi Z, Domocos DT, Carstens M, Carstens E, Hwang ST
Journal of cellular and molecular medicine 2019 Jul;23(7):4819-4828
Journal of cellular and molecular medicine 2019 Jul;23(7):4819-4828
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRPA1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human TRPA1. This antibody recognizes human antigen. The TRPA1 antibody has been validated for the following applications: ELISA, WB analysis.
