PAB11993

antibody from Abnova Corporation

Targeting: TPX2 C20orf1, C20orf2, DIL-2, p100

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB11993

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB11993, RRID:AB_1716384

Product name

TPX2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against partial recombinant TPX2.

Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B, Del Castillo Velasco-Herrera M, Edwards A, van der Weyden L, Yang F, Sanger Mouse Genetics Project, Ramirez-Solis R, Estabel J, Gallagher FA, Logan DW, Arends MJ, Tsang SH, Mahajan VB, Scudamore CL, White JK, Jackson SP, Gergely F, Adams DJ
PLoS genetics 2012;8(11):e1003022

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A survivin-ran complex regulates spindle formation in tumor cells.

Xia F, Canovas PM, Guadagno TM, Altieri DC
Molecular and cellular biology 2008 Sep;28(17):5299-311

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Tumor cell dependence on Ran-GTP-directed mitosis.

Xia F, Lee CW, Altieri DC
Cancer research 2008 Mar 15;68(6):1826-33

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Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.

Bird AW, Hyman AA
The Journal of cell biology 2008 Jul 28;182(2):289-300

Immunocytochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunofluorescence staining of TPX2 on nuclears of HeLa cells fixed in 3.5% paraformaldehyde during interphase and spindle staining during mitosis with TPX2 polyclonal antibody at 1 : 1000 (Cat # PAB11993).

Validation comment

Immunofluorescence