AMM01736G

antibody from Leading Biology

Targeting: TPX2 C20orf1, C20orf2, DIL-2, p100

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM01736G

Provider

Leading Biology

Product name

TPX2 Antibody (clone 18D5)

Antibody type

Monoclonal

Description

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

Reactivity

Human

Host

Mouse

Antibody clone number

18D5

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.