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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA005487 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA005487, RRID:AB_1858223
- Product name
- Anti-TPX2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TPX2, Gene description: TPX2, microtubule-associated, Alternative Gene Names: C20orf1, C20orf2, DIL-2, p100, Validated applications: ICC, IHC, WB, Uniprot ID: Q9ULW0, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references A human stomach cell type transcriptome atlas.
TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer.
MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
Overexpression of TPX2 is associated with progression and prognosis of prostate cancer
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
Öling S, Struck E, Noreen-Thorsen M, Zwahlen M, von Feilitzen K, Odeberg J, Pontén F, Lindskog C, Uhlén M, Dusart P, Butler LM
BMC biology 2024 Feb 14;22(1):36
BMC biology 2024 Feb 14;22(1):36
TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer.
Guenther M, Surendran SA, Haas M, Heinemann V, von Bergwelt-Baildon M, Engel J, Werner J, Boeck S, Ormanns S
British journal of cancer 2023 Jul;129(1):175-182
British journal of cancer 2023 Jul;129(1):175-182
MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities
Rohrberg J, Van de Mark D, Amouzgar M, Lee J, Taileb M, Corella A, Kilinc S, Williams J, Jokisch M, Camarda R, Balakrishnan S, Shankar R, Zhou A, Chang A, Chen B, Rugo H, Dumont S, Goga A
Cell Reports 2020;30(10):3368-3382.e7
Cell Reports 2020;30(10):3368-3382.e7
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
Shah K, Bhatt R, Rotow J, Rohrberg J, Olivas V, Wang V, Hemmati G, Martins M, Maynard A, Kuhn J, Galeas J, Donnella H, Kaushik S, Ku A, Dumont S, Krings G, Haringsma H, Robillard L, Simmons A, Harding T, McCormick F, Goga A, Blakely C, Bivona T, Bandyopadhyay S
Nature Medicine 2018;25(1):111-118
Nature Medicine 2018;25(1):111-118
Overexpression of TPX2 is associated with progression and prognosis of prostate cancer
Zou J, Huang R, Jiang F, Chen D, Wang C, Han Z, Liang Y, Zhong W
Oncology Letters 2018
Oncology Letters 2018
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
Stadler C, Rexhepaj E, Singan V, Murphy R, Pepperkok R, Uhlén M, Simpson J, Lundberg E
Nature Methods 2013;10(4):315-323
Nature Methods 2013;10(4):315-323
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and pancreas tissues using HPA005487 antibody. Corresponding TPX2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
