Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS9275 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Nrf3 (D530) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 500-520 of Human Nrf3.
- Description
- Nrf3 (nuclear factor (erythroid-derived 2)-like 3, NFE2L3, NF-E2-related factor 3, NRF3) is a transcription factor that influences placental gene expression and development. Nrf3 contains a Cap'n'collar (CNC)-type basic leucine zipper (bZIP) domain, and belongs to the CNC gene family. CNC genes play important roles in development, differentiation, oncogenesis, and stress signaling. Nrf3 protein is detectable in primary placental cytotrophoblasts. The human choriocarcinoma cell lines BeWo and JAR from trophoblastic tumors of the placenta express Nrf3 transcripts. Nrf3/MAFG heterodimers recognize nuclear factor-erythroid 2/Maf recognition element-type DNA-binding motifs. Keratinocyte growth factor (KGF)-regulates Nrf3-dependent gene expression during cutaneous wound repair.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of Nrf3 (D530) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate