Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 12450-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12450-1-AP, RRID:AB_2201139
- Product name
- TCEB1 antibody
- Antibody type
- Polyclonal
- Description
- TCEB1 antibody (Cat. #12450-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references APP ubiquitination by VHL protein is essential for MVB sorting and lysosomal degradation.
Covariation MS uncovers a protein that controls cysteine catabolism.
SINE compounds activate exportin-1 degradation via an allosteric mechanism.
Opposing roles of pseudokinases NRBP1 and NRBP2 in regulating L1 retrotransposition.
SINE compounds activate exportin 1 degradation through an allosteric mechanism.
The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.
The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.
CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14(ARF) degradation.
Antiosteoporotic Effects of Huangqi Sanxian Decoction in Cultured Rat Osteoblasts by Proteomic Characterization of the Target and Mechanism.
A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression.
Shan C, Cong R, Xu X, Li Y, Tian Y, Cao W, Zhao W, Miao L, Teng J, Huang N, Chen J
Journal of molecular cell biology 2026 Mar 2;17(8)
Journal of molecular cell biology 2026 Mar 2;17(8)
Covariation MS uncovers a protein that controls cysteine catabolism.
Xiao H, Ordonez M, Fink EC, Covington TA, Woldemichael HB, Chen J, Jain MS, Rohatgi MH, Wei SM, Burger N, Sharif MA, Jan J, Wang Y, Petrocelli JJ, Blackmore K, Smythers AL, Zhang B, Gilbert M, Cheong H, Khetarpal SA, Smith A, Bogoslavski D, Lei Y, Vaites LP, McAllister FE, Van Bruggen N, Donovan KA, Huttlin EL, Mills EL, Fischer ES, Chouchani ET
Nature 2025 Nov;647(8088):268-276
Nature 2025 Nov;647(8088):268-276
SINE compounds activate exportin-1 degradation via an allosteric mechanism.
Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM
bioRxiv : the preprint server for biology 2025 Jun 9;
bioRxiv : the preprint server for biology 2025 Jun 9;
Opposing roles of pseudokinases NRBP1 and NRBP2 in regulating L1 retrotransposition.
Yang W, Cong S, Li R, Schwarz J, Schulze T, Gevelhoff RA, Chen X, Ullrich S, Falkenstein K, Ott D, Eixmann P, Trentino A, Thien A, Heidmann T, Schulze E, Warscheid B, Baumeister R, Qi W
Nature communications 2025 Jul 11;16(1):6327
Nature communications 2025 Jul 11;16(1):6327
SINE compounds activate exportin 1 degradation through an allosteric mechanism.
Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM
Nature chemical biology 2025 Dec;21(12):2002-2013
Nature chemical biology 2025 Dec;21(12):2002-2013
The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.
Wąchalska M, Riepe C, Ślusarz MJ, Graul M, Borowski LS, Qiao W, Foltyńska M, Carette JE, Bieńkowska-Szewczyk K, Szczesny RJ, Kopito RR, Lipińska AD
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2309841121
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2309841121
The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.
Wąhalska M, Riepe C, Ślusarz MJ, Graul M, Borowski LS, Qiao W, Foltynska M, Carette JE, Bieńkowska-Szewczyk K, Szczesny RJ, Kopito RR, Lipińska AD
bioRxiv : the preprint server for biology 2023 Sep 27;
bioRxiv : the preprint server for biology 2023 Sep 27;
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.
Mu M, Zhang Q, Li J, Zhao C, Li X, Chen Z, Sun X, Yu J
Cell death and differentiation 2023 Nov;30(11):2393-2407
Cell death and differentiation 2023 Nov;30(11):2393-2407
CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14(ARF) degradation.
Zhang P, Gao K, Zhang L, Sun H, Zhao X, Liu Y, Lv Z, Shi Q, Chen Y, Jiao D, Li Y, Gu W, Wang C
Cell death and differentiation 2022 Apr;29(4):758-771
Cell death and differentiation 2022 Apr;29(4):758-771
Antiosteoporotic Effects of Huangqi Sanxian Decoction in Cultured Rat Osteoblasts by Proteomic Characterization of the Target and Mechanism.
Guo CC, Zheng LH, Fu JY, Zhu JH, Zhou YX, Zeng T, Zhou ZK
Evidence-based complementary and alternative medicine : eCAM 2015;2015:514063
Evidence-based complementary and alternative medicine : eCAM 2015;2015:514063
A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression.
Agell L, Hernández S, Nonell L, Lorenzo M, Puigdecanet E, de Muga S, Juanpere N, Bermudo R, Fernández PL, Lorente JA, Serrano S, Lloreta J
The American journal of pathology 2012 Nov;181(5):1585-94
The American journal of pathology 2012 Nov;181(5):1585-94
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 12450-1-AP(TCEB1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TCEB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TCEB1. This antibody recognizes human,mouse,rat antigen. The TCEB1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.