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- References [19]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 11784-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11784-1-AP, RRID:AB_2138089
- Product name
- LY96/MD2 antibody
- Antibody type
- Polyclonal
- Description
- LY96/MD2 antibody (Cat. #11784-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MD2 mediates COPD pathogenesis by inducing airway inflammation and ferroptosis through the TLR4/MyD88 pathway.
Ly96-mediated activation of TGF-β1/Smad2/3 signaling in hepatocellular carcinoma and its potential for nanoparticle-based therapy.
The NLRP3 activation-related signature predicts the diagnosis and indicates immune characteristics in endometriosis.
Clec7a Signaling in Microglia Promotes Synapse Loss Associated with Tauopathy.
The protective effect of amitriptyline on experimental colitis through inhibiting TLR-4/MD-2 signaling pathway.
Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.
Molecular profiling reveals the malignant potential in solid pseudopapillary neoplasms of the pancreas.
The effects and mechanisms of AM1241 in alleviating cerebral ischemia-reperfusion injury.
Clec7a Worsens Long-Term Outcomes after Ischemic Stroke by Aggravating Microglia-Mediated Synapse Elimination.
Fragment-Based Anti-inflammatory Agent Design and Target Identification: Discovery of AF-45 as an IRAK4 Inhibitor to Treat Ulcerative Colitis and Acute Lung Injury.
Discovery of pyrazolo[1,5-a]pyrimidine derivatives targeting TLR4-TLR4∗ homodimerization via AI-powered next-generation screening.
Association of M2 macrophages with EMT in glioma identified through combination of multi-omics and machine learning.
A novel immunogenic cell death-related subtype classification and risk signature for predicting prognosis and immunotherapy efficacy in gastric cancer.
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
MD2 Is a Potential Biomarker Associated with Immune Cell Infiltration in Gliomas.
Macrophage CD36 and TLR4 Cooperation Promotes Foam Cell Formation and VSMC Migration and Proliferation Under Circadian Oscillations.
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
Curcumin inhibits cell proliferation and migration in NSCLC through a synergistic effect on the TLR4/MyD88 and EGFR pathways.
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Xi X, Chen H, Ji H, Xiao T, Liu Z, Chen J, Ge X, Zhang Y, Zhu X
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168099
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168099
Ly96-mediated activation of TGF-β1/Smad2/3 signaling in hepatocellular carcinoma and its potential for nanoparticle-based therapy.
Zhang Y, Zheng S, Su X, Luo W, Tang H, Xiong S, Tan M, Luo B
Acta biochimica et biophysica Sinica 2025 Nov 3;58(4):865-81
Acta biochimica et biophysica Sinica 2025 Nov 3;58(4):865-81
The NLRP3 activation-related signature predicts the diagnosis and indicates immune characteristics in endometriosis.
Nong W, Wei H, Dou S, He L, Lin L, Lu D, Wei B, Zhang S, Huo P, Dong M
Journal of reproductive immunology 2025 Mar;168:104443
Journal of reproductive immunology 2025 Mar;168:104443
Clec7a Signaling in Microglia Promotes Synapse Loss Associated with Tauopathy.
Yang S, Wang J, Cao Y, Zhang Y, Sun Z, Wan P, Pi M, Xiong Q, Shu X, Wang X, Xia Y
International journal of molecular sciences 2025 Mar 22;26(7)
International journal of molecular sciences 2025 Mar 22;26(7)
The protective effect of amitriptyline on experimental colitis through inhibiting TLR-4/MD-2 signaling pathway.
Zeng C, Zhu Q, Peng W, Huang C, Chen H, Huang H, Zhou Y, Zhao C
The Journal of pharmacology and experimental therapeutics 2025 Jan;392(1):100024
The Journal of pharmacology and experimental therapeutics 2025 Jan;392(1):100024
Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.
Li G, Zhao Y, He Y, Qian Z, Liu Y, Li X, Li L, Liu Z
Scientific reports 2025 Aug 19;15(1):30417
Scientific reports 2025 Aug 19;15(1):30417
Molecular profiling reveals the malignant potential in solid pseudopapillary neoplasms of the pancreas.
Li J, Zheng H, Zhang X, Pan B, Lu J, Zhou L, Zhang T, Dai M, Guo J, Wang W, Han X, Xu Q, Hua Y, Kleeff J, Wu H, Liang Z, Liu Q, Liao Q
Cancer letters 2025 Aug 10;625:217788
Cancer letters 2025 Aug 10;625:217788
The effects and mechanisms of AM1241 in alleviating cerebral ischemia-reperfusion injury.
Li S, Yang P, Wu Z, Huang W, Zhu X, Zhong L
Brain research bulletin 2024 Sep;215:111025
Brain research bulletin 2024 Sep;215:111025
Clec7a Worsens Long-Term Outcomes after Ischemic Stroke by Aggravating Microglia-Mediated Synapse Elimination.
Wan H, He M, Cheng C, Yang K, Wu H, Cong P, Huang X, Zhang Q, Shi Y, Hu J, Tian L, Xiong L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2403064
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2403064
Fragment-Based Anti-inflammatory Agent Design and Target Identification: Discovery of AF-45 as an IRAK4 Inhibitor to Treat Ulcerative Colitis and Acute Lung Injury.
Zou Y, Wang X, Chen P, Zheng Z, Li X, Chen Z, Guo M, Zhou Y, Sun C, Wang R, Zhu W, Zheng P, Cho WJ, Cho YC, Liang G, Tang Q
Journal of medicinal chemistry 2024 Jul 11;67(13):10687-10709
Journal of medicinal chemistry 2024 Jul 11;67(13):10687-10709
Discovery of pyrazolo[1,5-a]pyrimidine derivatives targeting TLR4-TLR4∗ homodimerization via AI-powered next-generation screening.
Jiang YY, Yan ST, Zhang SZ, Wang M, Diao WM, Li J, Fang XM, Yin H
European journal of medicinal chemistry 2024 Dec 15;280:116945
European journal of medicinal chemistry 2024 Dec 15;280:116945
Association of M2 macrophages with EMT in glioma identified through combination of multi-omics and machine learning.
Feng P, Liu S, Yuan G, Pan Y
Heliyon 2024 Aug 15;10(15):e34119
Heliyon 2024 Aug 15;10(15):e34119
A novel immunogenic cell death-related subtype classification and risk signature for predicting prognosis and immunotherapy efficacy in gastric cancer.
Dong B, Wu Y, Zhang J, Gu Y, Xie R, He X, Pang X, Wang X, Cui Y
Frontiers in immunology 2023;14:1162876
Frontiers in immunology 2023;14:1162876
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Zhang J, Sun Y, Sun C, Shang D
Bioorganic chemistry 2023 Mar;132:106376
Bioorganic chemistry 2023 Mar;132:106376
MD2 Is a Potential Biomarker Associated with Immune Cell Infiltration in Gliomas.
Zhao M, Li X, Chen Y, Wang S
Frontiers in oncology 2022;12:854598
Frontiers in oncology 2022;12:854598
Macrophage CD36 and TLR4 Cooperation Promotes Foam Cell Formation and VSMC Migration and Proliferation Under Circadian Oscillations.
Sun Z, Yuan W, Li L, Cai H, Mao X, Zhang L, Zang G, Wang Z
Journal of cardiovascular translational research 2022 Oct;15(5):985-997
Journal of cardiovascular translational research 2022 Oct;15(5):985-997
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
Zhang M, Zhang J, Wang C, Yan JK, Yi J, Ning J, Huo XK, Yu ZL, Zhang BJ, Sun CP, Ma XC
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15104-15115
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15104-15115
Curcumin inhibits cell proliferation and migration in NSCLC through a synergistic effect on the TLR4/MyD88 and EGFR pathways.
Zhang L, Tao X, Fu Q, Ge C, Li R, Li Z, Zhu Y, Tian H, Li Q, Liu M, Hu H, Zeng B, Lin Z, Li C, Luo R, Song X
Oncology reports 2019 Nov;42(5):1843-1855
Oncology reports 2019 Nov;42(5):1843-1855
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hu Y, Li Q, Pan Y, Xu L
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- U-937 cells were subjected to SDS PAGE followed by western blot with 11784-1-AP(LY96 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 11784-1-AP(LY96 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LY96 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LY96. This antibody recognizes human antigen. The LY96 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
