ABIN2192086

antibody from antibodies-online

Targeting: LY96 MD-2

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN2192086

Provider

antibodies-online

Product name

anti-Lymphocyte Antigen 96 (LY96) antibody (Biotin)

Antibody type

Monoclonal

Antigen

TLR4/MD-2 expressing CHO cells/ chimeric TLR4/MD-2 fusion protein

Reactivity

Human

Host

Mouse

Conjugate

Biotin

Antibody clone number

18H10

Vial size

50 μg

Storage

Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year.

References

Submitted references

Soluble MD-2 is an acute-phase protein and an opsonin for Gram-negative bacteria.

Tissières P, Dunn-Siegrist I, Schäppi M, Elson G, Comte R, Nobre V, Pugin J
Blood 2008 Feb 15;111(4):2122-31

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TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock.

Daubeuf B, Mathison J, Spiller S, Hugues S, Herren S, Ferlin W, Kosco-Vilbois M, Wagner H, Kirschning CJ, Ulevitch R, Elson G
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 1;179(9):6107-14

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Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria.

Elson G, Dunn-Siegrist I, Daubeuf B, Pugin J
Blood 2007 Feb 15;109(4):1574-83

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Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock.

Pugin J, Stern-Voeffray S, Daubeuf B, Matthay MA, Elson G, Dunn-Siegrist I
Blood 2004 Dec 15;104(13):4071-9