Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12771-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12771-1-AP, RRID:AB_2137677
- Product name
- MAFF antibody
- Antibody type
- Polyclonal
- Description
- MAFF antibody (Cat. #12771-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NFE2L1/Nrf1 forms a coactivator complex post-peptide:N-glycanase-mediated sequence editing and mitigates proteasome dysfunction.
MAFF drives pancreatic cancer progression through AKR1C1-mediated inhibition of ferroptosis.
The effects of hepatocyte-specific MafF overexpression on FFA or ETOH induced hepatocyte steatosis and its underlying mechanism.
The interplay between hormonal vitamin D and lipopolysaccharide signaling on human neutrophil transcriptional responses.
MAFF inhibits angiogenesis in non-small cell lung cancer by suppressing YAP1 nuclear translocation.
Identification of mitochondria-related genes associated with anesthetics in patients undergoing off-pump coronary artery bypass grafting surgery.
PLK3-Activated Mitochondrial Apoptosis Pathway in the Pathogenesis of Sepsis-Associated Acute Kidney Injury.
MAFF alleviates hepatic ischemia-reperfusion injury by regulating the CLCF1/STAT3 signaling pathway.
PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer.
Targeted insertion of conditional expression cassettes into the mouse genome using the modified i-PITT.
Distinct Perception Mechanisms of BACH1 Quaternary Structure Degrons by Two F-box Proteins under Oxidative Stress.
Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.
MAFF mediates PEITC-induced enhancement of sensitivity to carboplatin in ovarian cancer cell lines via activating ZNF711 transcription in vivo and invitro.
Reduced SUMOylation of Nrf2 signaling contributes to its inhibition induced by amyloid-β.
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
The FACT complex facilitates expression of lysosomal and antioxidant genes through binding to TFEB and TFE3.
Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
miR-320a induces pancreatic β cells dysfunction in diabetes by inhibiting MafF.
Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.
Global polysome analysis of normal and injured podocytes.
Yoshida Y, Okada M, Arai N, Ando C, Kinoshita D, Nishito Y, Kametani F, Hasegawa M, Tanaka K, Endo A
Proceedings of the National Academy of Sciences of the United States of America 2026 Jan 6;123(1):e2517547123
Proceedings of the National Academy of Sciences of the United States of America 2026 Jan 6;123(1):e2517547123
MAFF drives pancreatic cancer progression through AKR1C1-mediated inhibition of ferroptosis.
Jiang X, Chen X, Xia J, Zhou B, Zhang A, Chen Y, She Q, Li Y, Ding Y, Zhang M
QJM : monthly journal of the Association of Physicians 2026 Apr 1;119(4):271-281
QJM : monthly journal of the Association of Physicians 2026 Apr 1;119(4):271-281
The effects of hepatocyte-specific MafF overexpression on FFA or ETOH induced hepatocyte steatosis and its underlying mechanism.
Cai J, Wang S, Feng Y, Zheng L, Liang Q, Liang Y, Ye X
Hepatology forum 2025;6(3):91-98
Hepatology forum 2025;6(3):91-98
The interplay between hormonal vitamin D and lipopolysaccharide signaling on human neutrophil transcriptional responses.
Ismailova A, Salehi-Tabar R, Ismailova N, Dumas O, Saliba J, Blank V, White JH
Frontiers in immunology 2025;16:1683913
Frontiers in immunology 2025;16:1683913
MAFF inhibits angiogenesis in non-small cell lung cancer by suppressing YAP1 nuclear translocation.
Ding Y, Wang S, Hu R, Cao Z, Zou Y, Yang WL, Ji W, Liu L, Xiao N, Li XL, Zeng Y
PeerJ 2025;13:e20395
PeerJ 2025;13:e20395
Identification of mitochondria-related genes associated with anesthetics in patients undergoing off-pump coronary artery bypass grafting surgery.
Zhang Y, Li X, Sun T
Frontiers in surgery 2025;12:1515732
Frontiers in surgery 2025;12:1515732
PLK3-Activated Mitochondrial Apoptosis Pathway in the Pathogenesis of Sepsis-Associated Acute Kidney Injury.
Jiang P, Chen R, Wu K, Wang J, Chen M, Qin J, Zhu J
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70462
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70462
MAFF alleviates hepatic ischemia-reperfusion injury by regulating the CLCF1/STAT3 signaling pathway.
Lei D, Wang Y, Li S, Xiang S, Luo Y, Yan P, Luo F, Huang Z, Wu Z
Cellular & molecular biology letters 2025 Apr 1;30(1):39
Cellular & molecular biology letters 2025 Apr 1;30(1):39
PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer.
Nguyen CDK, Colón-Emeric BA, Murakami S, Shujath MNY, Yi C
Cell reports 2024 May 28;43(5):114176
Cell reports 2024 May 28;43(5):114176
Targeted insertion of conditional expression cassettes into the mouse genome using the modified i-PITT.
Miura H, Nakamura A, Kurosaki A, Kotani A, Motojima M, Tanaka K, Kakuta S, Ogiwara S, Ohmi Y, Komaba H, Schilit SLP, Morton CC, Gurumurthy CB, Ohtsuka M
BMC genomics 2024 Jun 5;25(1):568
BMC genomics 2024 Jun 5;25(1):568
Distinct Perception Mechanisms of BACH1 Quaternary Structure Degrons by Two F-box Proteins under Oxidative Stress.
Cao S, Shi H, Garcia SF, Kito Y, Shi H, Goldberg HV, Ponce J, Ueberheide B, Lignitto L, Pagano M, Zheng N
bioRxiv : the preprint server for biology 2024 Jun 3;
bioRxiv : the preprint server for biology 2024 Jun 3;
Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.
Cao S, Garcia SF, Shi H, James EI, Kito Y, Shi H, Mao H, Kaisari S, Rona G, Deng S, Goldberg HV, Ponce J, Ueberheide B, Lignitto L, Guttman M, Pagano M, Zheng N
Cell 2024 Dec 26;187(26):7568-7584.e22
Cell 2024 Dec 26;187(26):7568-7584.e22
MAFF mediates PEITC-induced enhancement of sensitivity to carboplatin in ovarian cancer cell lines via activating ZNF711 transcription in vivo and invitro.
Luan M, Zhang B, Wei Y, Liu F, Zhao Y, Yu Y, Wu Q
Chemico-biological interactions 2024 Aug 25;399:111116
Chemico-biological interactions 2024 Aug 25;399:111116
Reduced SUMOylation of Nrf2 signaling contributes to its inhibition induced by amyloid-β.
Wang P, Wang X, Qiao K, Zhang Y, Nie Q, Cui J, Sun J, Li L
Neuroscience letters 2023 Mar 16;799:137118
Neuroscience letters 2023 Mar 16;799:137118
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X
Molecular oncology 2023 Apr;17(4):695-709
Molecular oncology 2023 Apr;17(4):695-709
The FACT complex facilitates expression of lysosomal and antioxidant genes through binding to TFEB and TFE3.
Jeong E, Martina JA, Contreras PS, Lee J, Puertollano R
Autophagy 2022 Oct;18(10):2333-2349
Autophagy 2022 Oct;18(10):2333-2349
Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
Chen Z, Lu T, Huang L, Wang Z, Yan Z, Guan Y, Hu W, Fan Z, Zhu P
The Journal of clinical investigation 2021 Oct 1;131(19)
The Journal of clinical investigation 2021 Oct 1;131(19)
miR-320a induces pancreatic β cells dysfunction in diabetes by inhibiting MafF.
Du H, Yin Z, Zhao Y, Li H, Dai B, Fan J, He M, Nie X, Wang CY, Wang DW, Chen C
Molecular therapy. Nucleic acids 2021 Dec 3;26:444-457
Molecular therapy. Nucleic acids 2021 Dec 3;26:444-457
Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.
Wang X, Zhang Y, Wan X, Guo C, Cui J, Sun J, Li L
Disease markers 2020;2020:8861358
Disease markers 2020;2020:8861358
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Jiang TY, Pan YF, Wan ZH, Lin YK, Zhu B, Yuan ZG, Ma YH, Shi YY, Zeng TM, Dong LW, Tan YX, Wang HY
Science translational medicine 2020 Sep 23;12(562)
Science translational medicine 2020 Sep 23;12(562)
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.
Shen S, Yang C, Liu X, Zheng J, Liu Y, Liu L, Ma J, Ma T, An P, Lin Y, Cai H, Wang D, Li Z, Zhao L, Xue Y
Molecular therapy oncolytics 2020 Jun 26;17:138-152
Molecular therapy oncolytics 2020 Jun 26;17:138-152
Global polysome analysis of normal and injured podocytes.
Okabe M, Motojima M, Miyazaki Y, Pastan I, Yokoo T, Matsusaka T
American journal of physiology. Renal physiology 2019 Feb 1;316(2):F241-F252
American journal of physiology. Renal physiology 2019 Feb 1;316(2):F241-F252
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human lung tissue were subjected to SDS PAGE followed by western blot with 12771-1-AP(MAFF antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The MAFF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MAFF. This antibody recognizes human, mouse, rat antigen. The MAFF antibody has been validated for the following applications: ELISA, WB, IHC analysis.