APR03539G

antibody from Leading Biology

Targeting: FBH1 Fbx18, FBXO18, FLJ14590

Western blot (Recommended by provider)

Antibody Data

Product number

APR03539G

Provider

Leading Biology

Product name

FBXO18 Antibody (C-term)

Antibody type

Polyclonal

Description

This gene encodes a member of the F-box protein family,members of which are characterized by an approximately 40 aminoacid motif, the F-box. The F-box proteins constitute one of thefour subunits of ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into three classes:Fbws containing WD-40 domains, Fbls containing leucine-richrepeats, and Fbxs containing either different protein-proteininteraction modules or no recognizable motifs. The protein encodedby this gene belongs to the Fbx class. It contains an F-box motifand seven conserved helicase motifs, and has both DNA-dependentATPase and DNA unwinding activities. Alternatively splicedtranscript variants encoding distinct isoforms have been identifiedfor this gene.

Reactivity

Mouse

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.