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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Immunohistochemistry [1]
- Flow cytometry [2]
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- Product number
- PA5-23608 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- ALOX12B Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with mouse and rat based on sequence homology.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µL
- Concentration
- 1.7 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references ALOX12B promotes carcinogenesis in cervical cancer by regulating the PI3K/ERK1 signaling pathway.
12R-lipoxygenase activity is reduced in photodamaged facial stratum corneum. A novel activity assay indicates a key function in corneocyte maturation.
Phospho-ΔNp63α regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation.
Jiang T, Zhou B, Li YM, Yang QY, Tu KJ, Li LY
Oncology letters 2020 Aug;20(2):1360-1368
Oncology letters 2020 Aug;20(2):1360-1368
12R-lipoxygenase activity is reduced in photodamaged facial stratum corneum. A novel activity assay indicates a key function in corneocyte maturation.
Guneri D, Voegeli R, Munday MR, Lane ME, Rawlings AV
International journal of cosmetic science 2019 Jun;41(3):274-280
International journal of cosmetic science 2019 Jun;41(3):274-280
Phospho-ΔNp63α regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation.
Ratovitski EA
FEBS letters 2013 Nov 1;587(21):3581-6
FEBS letters 2013 Nov 1;587(21):3581-6
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of ALOX12B in formalin fixed and paraffin embedded human tonsil tissue. Samples were incubated with ALOX12B polyclonal antibody (Product # PA5-23608) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry analysis of A549 cells using an ALOX12B polyclonal antibody (Product # PA5-23608) (right) compared to a negative control cell (left) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry of ALOX12B in A549 cells (right histogram). Samples were incubated with ALOX12B polyclonal antibody (Product # PA5-23608) followed by FITC-conjugated goat-anti-rabbit secondary antibody. Negative control cell (left histogram).
