ABIN394054
antibody from antibodies-online
Targeting: HEY1
bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- ABIN394054 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 121-221) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 121-221
- Isotype
- IgG
- Antibody clone number
- 1F11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references The Notch effector Hey1 associates with myogenic target genes to repress myogenesis.
HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions.
Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway.
Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.
High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.
Buas MF, Kabak S, Kadesch T
The Journal of biological chemistry 2010 Jan 8;285(2):1249-58
The Journal of biological chemistry 2010 Jan 8;285(2):1249-58
HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions.
Villaronga MA, Lavery DN, Bevan CL, Llanos S, Belandia B
Oncogene 2010 Jan 21;29(3):411-20
Oncogene 2010 Jan 21;29(3):411-20
Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway.
Gould F, Harrison SM, Hewitt EW, Whitehouse A
Journal of virology 2009 Jul;83(13):6727-38
Journal of virology 2009 Jul;83(13):6727-38
Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.
Sharff KA, Song WX, Luo X, Tang N, Luo J, Chen J, Bi Y, He BC, Huang J, Li X, Jiang W, Zhu GH, Su Y, He Y, Shen J, Wang Y, Chen L, Zuo GW, Liu B, Pan X, Reid RR, Luu HH, Haydon RC, He TC
The Journal of biological chemistry 2009 Jan 2;284(1):649-59
The Journal of biological chemistry 2009 Jan 2;284(1):649-59
High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.
Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, MrOS Research Group.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009 Dec;24(12):2039-49
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009 Dec;24(12):2039-49
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA