Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11609-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11609-1-AP, RRID:AB_2292188
- Product name
- CPSF3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPSF3 antibody (Cat. #11609-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3' end processing factors.
Mutual regulation between cell cycle and transcription termination factor TTF2.
RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation.
Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Single-cell multi-omics profiling reveals key regulatory mechanisms that poise germinal vesicle oocytes for maturation in pigs.
CPSF3 Promotes Pre-mRNA Splicing and Prevents CircRNA Cyclization in Hepatocellular Carcinoma.
Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome.
LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
Lu C, Bai X, Zhang H, Zhang Y, Yang M, Zheng Y, Jin Z, Yang W, Guo G, Huang Q, Huang Y, Wu L, Fu XD, Zhang Z, Wang G
Molecular cell 2025 Jun 5;85(11):2147-2164.e10
Molecular cell 2025 Jun 5;85(11):2147-2164.e10
Mutual regulation between cell cycle and transcription termination factor TTF2.
Hu Y, Xu L, Feng B, Wu Q, Wang Y, Gong W, Lv M, Zhao H, Chen J, Li J, Zhang W, Zhan Q
Science China. Life sciences 2025 Aug;68(8):2348-2362
Science China. Life sciences 2025 Aug;68(8):2348-2362
RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation.
Lin P, Chen W, Long Z, Yu J, Yang J, Xia Z, Wu Q, Min X, Tang J, Cui Y, Liu F, Wang C, Zheng J, Li W, Rich JN, Li L, Xie Q
Cell discovery 2024 Mar 19;10(1):32
Cell discovery 2024 Mar 19;10(1):32
Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Tao Y, Budhipramono A, Huang J, Fang M, Xie S, Kim J, Khivansara V, Dominski Z, Tong L, De Brabander JK, Nijhawan D
Cell chemical biology 2024 Jan 18;31(1):139-149.e14
Cell chemical biology 2024 Jan 18;31(1):139-149.e14
Single-cell multi-omics profiling reveals key regulatory mechanisms that poise germinal vesicle oocytes for maturation in pigs.
Yuan X, Chen N, Feng Y, Li N, Pan X, Tian Y, Wang J, Jiang Y, He D, Li J, Gao F
Cellular and molecular life sciences : CMLS 2023 Jul 22;80(8):222
Cellular and molecular life sciences : CMLS 2023 Jul 22;80(8):222
CPSF3 Promotes Pre-mRNA Splicing and Prevents CircRNA Cyclization in Hepatocellular Carcinoma.
Huang Y, Ji H, Dong J, Wang X, He Z, Cheng Z, Zhu Q
Cancers 2023 Aug 11;15(16)
Cancers 2023 Aug 11;15(16)
Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome.
Ho JJD, Cunningham TA, Manara P, Coughlin CA, Arumov A, Roberts ER, Osteen A, Kumar P, Bilbao D, Krieger JR, Lee S, Schatz JH
Cell reports 2021 Oct 12;37(2):109806
Cell reports 2021 Oct 12;37(2):109806
LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
Luo K, Geng J, Zhang Q, Xu Y, Zhou X, Huang Z, Shi KQ, Pan C, Wu J
Journal of experimental & clinical cancer research : CR 2019 Jun 11;38(1):249
Journal of experimental & clinical cancer research : CR 2019 Jun 11;38(1):249
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CPSF3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CPSF3. This antibody recognizes human, mouse, rat antigen. The CPSF3 antibody has been validated for the following applications: ELISA, WB analysis.