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- References [31]
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- Product number
- 16277-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16277-1-AP, RRID:AB_2181292
- Product name
- RPL11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPL11 antibody (Cat. #16277-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine.
Amelioration of gamma irradiation-induced salivary gland damage in mice using melatonin.
Essential role of the amino-terminal region of Drosha for the Microprocessor function.
A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumors.
Dhx33 promotes B-cell growth and proliferation by controlling activation-induced rRNA upregulation.
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
UBE2T promotes glioblastoma malignancy through ubiquitination-mediated degradation of RPL6.
mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading.
METTL3 regulates m(6)A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma.
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer.
BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis.
UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11.
Inhibition of ribosomal RNA processing 15 Homolog (RRP15), which is overexpressed in hepatocellular carcinoma, suppresses tumour growth via induction of senescence and apoptosis.
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Control of ribosomal protein synthesis by the Microprocessor complex.
Deficiency of the Ribosomal Protein uL5 Leads to Significant Rearrangements of the Transcriptional and Translational Landscapes in Mammalian Cells.
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
RPL32 Promotes Lung Cancer Progression by Facilitating p53 Degradation.
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome.
Cellular sensitivity to UV-irradiation is mediated by RNA polymerase I transcription.
FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis.
Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway.
The ribosomal protein S26 regulates p53 activity in response to DNA damage.
Regulation of Actinomycin D induced upregulation of Mdm2 in H1299 cells.
Defective ribosome assembly in Shwachman-Diamond syndrome.
Shi X, Zhang Y, Wang Y, Wang J, Gao Y, Wang R, Wang L, Xiong M, Cao Y, Ou N, Liu Q, Ma H, Cai J, Chen H
Cell death and differentiation 2024 Sep;31(9):1219-1234
Cell death and differentiation 2024 Sep;31(9):1219-1234
Amelioration of gamma irradiation-induced salivary gland damage in mice using melatonin.
Ren J, Zhu T, Wang Z, Lu L, Fan S
Journal of pineal research 2023 Sep;75(2):e12897
Journal of pineal research 2023 Sep;75(2):e12897
Essential role of the amino-terminal region of Drosha for the Microprocessor function.
Prabhakar A, Hu S, Tang J, Ghatpande P, Lagna G, Jiang X, Hata A
iScience 2023 Oct 20;26(10):107971
iScience 2023 Oct 20;26(10):107971
A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumors.
Zhang C, Guo Q, Chen L, Wu Z, Yan XJ, Zou C, Zhang Q, Tan J, Fang T, Rao Q, Li Y, Shen S, Deng M, Wang L, Gao H, Yu J, Li H, Zhang C, Nowsheen S, Kloeber J, Zhao F, Yin P, Teng C, Lin Z, Song K, Yao S, Yao L, Wu L, Zhang Y, Cheng X, Gao Q, Yuan J, Lou Z, Zhang JS
Signal transduction and targeted therapy 2023 May 10;8(1):183
Signal transduction and targeted therapy 2023 May 10;8(1):183
Dhx33 promotes B-cell growth and proliferation by controlling activation-induced rRNA upregulation.
He X, Zhao J, Adilijiang A, Hong P, Chen P, Lin X, Xie J, Du Y, Liu Y, Lin L, Jin HY, Hong Y, Liu WH, Xiao C
Cellular & molecular immunology 2023 Mar;20(3):277-291
Cellular & molecular immunology 2023 Mar;20(3):277-291
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Chen J, Lei C, Zhang H, Huang X, Yang Y, Liu J, Jia Y, Shi H, Zhang Y, Zhang J, Du J
BMC molecular and cell biology 2023 Mar 3;24(1):7
BMC molecular and cell biology 2023 Mar 3;24(1):7
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Feng Y, Han Y, Hu A, Qu Y, Hu Y, Wu H, Wang X, He L
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
UBE2T promotes glioblastoma malignancy through ubiquitination-mediated degradation of RPL6.
Tao X, Wu X, Zhou P, Yu X, Zhao C, Peng X, Zhang K, Shen L, Peng J, Yang L
Cancer science 2023 Feb;114(2):521-532
Cancer science 2023 Feb;114(2):521-532
mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading.
Ogami K, Oishi Y, Sakamoto K, Okumura M, Yamagishi R, Inoue T, Hibino M, Nogimori T, Yamaguchi N, Furutachi K, Hosoda N, Inagaki H, Hoshino SI
Cell reports 2022 Oct 25;41(4):111548
Cell reports 2022 Oct 25;41(4):111548
METTL3 regulates m(6)A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma.
Zhang ZW, Teng X, Zhao F, Ma C, Zhang J, Xiao LF, Wang Y, Chang M, Tian Y, Li C, Zhang Z, Song S, Tong WM, Liu P, Niu Y
Cell reports 2022 Oct 25;41(4):111530
Cell reports 2022 Oct 25;41(4):111530
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Wang R, Peng C, Song J, Hua Y, Wu Q, Deng L, Cao Y, Zhang J, Zhang L, Wu L, Hou L
International journal of oncology 2022 Mar;60(3)
International journal of oncology 2022 Mar;60(3)
Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer.
Nakamura K, Reid BM, Chen A, Chen Z, Goode EL, Permuth JB, Teer JK, Tyrer J, Yu X, Kanetsky PA, Pharoah PD, Gayther SA, Sellers TA, Lawrenson K, Karreth FA
American journal of human genetics 2022 Jan 6;109(1):116-135
American journal of human genetics 2022 Jan 6;109(1):116-135
BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis.
Jia F, Wu Q, Wang Z, Zhang M, Yuan S, Che Y, Li B, Hu Z, Hu X
Oxidative medicine and cellular longevity 2021;2021:5986260
Oxidative medicine and cellular longevity 2021;2021:5986260
UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11.
Kim JH, Jung JH, Lee HJ, Sim DY, Im E, Park J, Park WY, Ahn CH, Shim BS, Kim B, Kim SH
Cancers 2021 Sep 29;13(19)
Cancers 2021 Sep 29;13(19)
Inhibition of ribosomal RNA processing 15 Homolog (RRP15), which is overexpressed in hepatocellular carcinoma, suppresses tumour growth via induction of senescence and apoptosis.
Zhao D, Qian L, Zhuang D, Wang L, Cao Y, Zhou F, Zhang S, Liu Y, Liang Y, Zhang W, Kang W, Zhang M, Wang Y, Zhang F, Zhang W, Xiao J, Xu G, Lv Y, Zou X, Zhuge Y, Zhang B
Cancer letters 2021 Oct 28;519:315-327
Cancer letters 2021 Oct 28;519:315-327
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Hao K, Chen Y, Yan X, Zhu X
Nature communications 2021 Nov 30;12(1):6971
Nature communications 2021 Nov 30;12(1):6971
Control of ribosomal protein synthesis by the Microprocessor complex.
Jiang X, Prabhakar A, Van der Voorn SM, Ghatpande P, Celona B, Venkataramanan S, Calviello L, Lin C, Wang W, Black BL, Floor SN, Lagna G, Hata A
Science signaling 2021 Feb 23;14(671)
Science signaling 2021 Feb 23;14(671)
Deficiency of the Ribosomal Protein uL5 Leads to Significant Rearrangements of the Transcriptional and Translational Landscapes in Mammalian Cells.
Babaylova ES, Gopanenko AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
International journal of molecular sciences 2021 Dec 15;22(24)
International journal of molecular sciences 2021 Dec 15;22(24)
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Cao P, Yang A, Li P, Xia X, Han Y, Zhou G, Wang R, Yang F, Li Y, Zhang Y, Cui Y, Ji H, Lu L, He F, Zhou G
Science advances 2021 Aug;7(35)
Science advances 2021 Aug;7(35)
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
RPL32 Promotes Lung Cancer Progression by Facilitating p53 Degradation.
Xie J, Zhang W, Liang X, Shuai C, Zhou Y, Pan H, Yang Y, Han W
Molecular therapy. Nucleic acids 2020 Sep 4;21:75-85
Molecular therapy. Nucleic acids 2020 Sep 4;21:75-85
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
Gopanenko AV, Kolobova AV, Meschaninova MI, Venyaminova AG, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Cells 2020 May 15;9(5)
Cells 2020 May 15;9(5)
Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome.
Alupei MC, Maity P, Esser PR, Krikki I, Tuorto F, Parlato R, Penzo M, Schelling A, Laugel V, Montanaro L, Scharffetter-Kochanek K, Iben S
Cell reports 2018 May 8;23(6):1612-1619
Cell reports 2018 May 8;23(6):1612-1619
Cellular sensitivity to UV-irradiation is mediated by RNA polymerase I transcription.
Assfalg R, Alupei MC, Wagner M, Koch S, Gonzalez OG, Schelling A, Scharffetter-Kochanek K, Iben S
PloS one 2017;12(6):e0179843
PloS one 2017;12(6):e0179843
FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.
Neben CL, Tuzon CT, Mao X, Lay FD, Merrill AE
Human molecular genetics 2017 Sep 1;26(17):3253-3270
Human molecular genetics 2017 Sep 1;26(17):3253-3270
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis.
Morgado-Palacin L, Varetti G, Llanos S, Gómez-López G, Martinez D, Serrano M
Cell reports 2015 Oct 27;13(4):712-722
Cell reports 2015 Oct 27;13(4):712-722
Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway.
Morgado-Palacin L, Llanos S, Urbano-Cuadrado M, Blanco-Aparicio C, Megias D, Pastor J, Serrano M
Carcinogenesis 2014 Dec;35(12):2822-30
Carcinogenesis 2014 Dec;35(12):2822-30
The ribosomal protein S26 regulates p53 activity in response to DNA damage.
Cui D, Li L, Lou H, Sun H, Ngai SM, Shao G, Tang J
Oncogene 2014 Apr 24;33(17):2225-35
Oncogene 2014 Apr 24;33(17):2225-35
Regulation of Actinomycin D induced upregulation of Mdm2 in H1299 cells.
Li L, Cui D, Zheng SJ, Lou H, Tang J
DNA repair 2012 Feb 1;11(2):112-9
DNA repair 2012 Feb 1;11(2):112-9
Defective ribosome assembly in Shwachman-Diamond syndrome.
Wong CC, Traynor D, Basse N, Kay RR, Warren AJ
Blood 2011 Oct 20;118(16):4305-12
Blood 2011 Oct 20;118(16):4305-12
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RPL11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPL11. This antibody recognizes human,mouse,rat antigen. The RPL11 antibody has been validated for the following applications: ELISA, WB analysis.
