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- Antibody Data
- Antigen structure
- References [18]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11005-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11005-1-AP, RRID:AB_2181760
- Product name
- RPL3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPL3 antibody (Cat. #11005-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ribosome remodeling drives translation adaptation during viral infection and cellular stress.
Rapid ER remodeling induced by a peptide-lipid complex in dying tumor cells.
The CDK8 kinase module: A novel player in the transcription of translation initiation and ribosomal genes.
Identification of coilin interactors reveals coordinated control of Cajal body number and structure.
Proteomics-based characterization of ribosome heterogeneity in adult mouse organs.
Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD.
TMEM232 is required for the formation of sperm flagellum and male fertility in mice.
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Phosphorylation of P-stalk proteins defines the ribosomal state for interaction with auxiliary protein factors.
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.
The Rab5 effector FERRY links early endosomes with mRNA localization.
Ribosomal RNA regulates chromosome clustering during mitosis.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance.
Preventing translational inhibition from ribosomal protein insufficiency by a herpes simplex virus-encoded ribosome-associated protein.
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Knockdown of Muscle-Specific Ribosomal Protein L3-Like Enhances Muscle Function in Healthy and Dystrophic Mice.
RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.
Tsai HY, Liu L, Fleming RH, Mintseris J, Ekanayake D, Gu X, Gygi SP, Lee ASY
bioRxiv : the preprint server for biology 2025 Oct 24;
bioRxiv : the preprint server for biology 2025 Oct 24;
Rapid ER remodeling induced by a peptide-lipid complex in dying tumor cells.
Sabari S, Chinchankar S, Ambite I, Nazari A, Carneiro APN, Svenningsson A, Svanborg C, Chaudhuri A
Life science alliance 2025 Jun;8(6)
Life science alliance 2025 Jun;8(6)
The CDK8 kinase module: A novel player in the transcription of translation initiation and ribosomal genes.
Friedson B, Willis SD, Shcherbik N, Campbell AN, Cooper KF
Molecular biology of the cell 2025 Jan 1;36(1):ar2
Molecular biology of the cell 2025 Jan 1;36(1):ar2
Identification of coilin interactors reveals coordinated control of Cajal body number and structure.
Arias Escayola D, Zhang C, Nischwitz E, Schärfen L, Dörner K, Straube K, Kutay U, Butter F, Neugebauer KM
The Journal of cell biology 2025 Feb 3;224(2)
The Journal of cell biology 2025 Feb 3;224(2)
Proteomics-based characterization of ribosome heterogeneity in adult mouse organs.
Brunchault MR, Hesse AM, Schaeffer J, Fröhlich A, Saintpierre A, Decourt C, Combes F, Nawabi H, Couté Y, Belin S
Cellular and molecular life sciences : CMLS 2025 Apr 24;82(1):175
Cellular and molecular life sciences : CMLS 2025 Apr 24;82(1):175
Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD.
Yang L, Niu K, Wang J, Shen W, Jiang R, Liu L, Song W, Wang X, Zhang X, Zhang R, Wei D, Fan M, Jia L, Tao K
Journal of hepatology 2024 Oct;81(4):651-666
Journal of hepatology 2024 Oct;81(4):651-666
TMEM232 is required for the formation of sperm flagellum and male fertility in mice.
Cai X, Zhang H, Kong S, Xu W, Zheng J, Wang N, He S, Li S, Shen Y, Wang K, Zhang Z, Cai H, Ma F, Bai S, Zhu F, Xiao F, Wang F
Cell death & disease 2024 Nov 8;15(11):806
Cell death & disease 2024 Nov 8;15(11):806
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Li S, Jin Z, Song X, Ma J, Peng Z, Yu H, Song J, Zhang Y, Sun X, He M, Yu X, Jin F, Zheng A
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Phosphorylation of P-stalk proteins defines the ribosomal state for interaction with auxiliary protein factors.
Filipek K, Blanchet S, Molestak E, Zaciura M, Wu CC, Horbowicz-Drożdżal P, Grela P, Zalewski M, Kmiecik S, González-Ibarra A, Krokowski D, Latoch P, Starosta AL, Mołoń M, Shao Y, Borkiewicz L, Michalec-Wawiórka B, Wawiórka L, Kubiński K, Socała K, Wlaź P, Cunningham KW, Green R, Rodnina MV, Tchórzewski M
EMBO reports 2024 Dec;25(12):5478-5506
EMBO reports 2024 Dec;25(12):5478-5506
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Park J, Wu J, Szkop KJ, Jeong J, Jovanovic P, Husmann D, Flores NM, Francis JW, Chen YC, Benitez AM, Zahn E, Song S, Ajani JA, Wang L, Singh K, Larsson O, Garcia BA, Topisirovic I, Gozani O, Mazur PK
Nature 2024 Aug;632(8025):656-663
Nature 2024 Aug;632(8025):656-663
Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.
Milenkovic I, Santos Vieira HG, Lucas MC, Ruiz-Orera J, Patone G, Kesteven S, Wu J, Feneley M, Espadas G, Sabidó E, Hübner N, van Heesch S, Völkers M, Novoa EM
Nucleic acids research 2023 Jun 23;51(11):5301-5324
Nucleic acids research 2023 Jun 23;51(11):5301-5324
The Rab5 effector FERRY links early endosomes with mRNA localization.
Schuhmacher JS, Tom Dieck S, Christoforidis S, Landerer C, Davila Gallesio J, Hersemann L, Seifert S, Schäfer R, Giner A, Toth-Petroczy A, Kalaidzidis Y, Bohnsack KE, Bohnsack MT, Schuman EM, Zerial M
Molecular cell 2023 Jun 1;83(11):1839-1855.e13
Molecular cell 2023 Jun 1;83(11):1839-1855.e13
Ribosomal RNA regulates chromosome clustering during mitosis.
Ma K, Luo M, Xie G, Wang X, Li Q, Gao L, Yu H, Yu X
Cell discovery 2022 May 31;8(1):51
Cell discovery 2022 May 31;8(1):51
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance.
Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S
eLife 2022 Jun 8;11
eLife 2022 Jun 8;11
Preventing translational inhibition from ribosomal protein insufficiency by a herpes simplex virus-encoded ribosome-associated protein.
Vink EI, Andrews J, Duffy C, Mohr I
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 9;118(45)
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 9;118(45)
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, Zhang Z, Gao B, Zhang C, Li M, Zhao L, Wang G
Carcinogenesis 2021 Feb 11;42(1):105-117
Carcinogenesis 2021 Feb 11;42(1):105-117
Knockdown of Muscle-Specific Ribosomal Protein L3-Like Enhances Muscle Function in Healthy and Dystrophic Mice.
Kao BR, Malerba A, Lu-Nguyen NB, Harish P, McCarthy JJ, Dickson G, Popplewell LJ
Nucleic acid therapeutics 2021 Dec;31(6):457-464
Nucleic acid therapeutics 2021 Dec;31(6):457-464
RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.
Chen C, Liu C, Niu Z, Li M, Zhang Y, Gao R, Chen H, Wang Q, Zhang S, Zhou R, Gan L, Zhang Z, Zhu T, Yu H, Liu J
Aging 2020 Jul 21;12(14):14490-14505
Aging 2020 Jul 21;12(14):14490-14505
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 11005-1-AP(RPL3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RPL3 antibody 11005-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 11005-1-AP(RPL3 antibody) at dilution of 1:10 (under 10x lens)
- Sample type
- tissue
