11889-1-AP
antibody from Proteintech Group
Targeting: AGGF1
FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q
Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11889-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11889-1-AP, RRID:AB_2305338
- Product name
- AGGF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AGGF1 antibody (Cat. #11889-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Diosgenin improves post-myocardial infarction cardiac function via HAND2-induced angiogenesis.
Decreased AGGF1 facilitates the progression of placenta accreta spectrum via mediating the P53 signaling pathway under the regulation of miR-1296-5p.
Aggf1 Specifies Hemangioblasts at the Top of Regulatory Hierarchy via Npas4l and mTOR-S6K-Emp2-ERK Signaling.
Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles.
Neuroprotective effect of AGGF1 against isoflurane-induced cognitive dysfunction in aged rats through activating the PI3K/AKT signaling pathways.
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells.
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
AGGF1 inhibits the expression of inflammatory mediators and promotes angiogenesis in dental pulp cells.
Angiogenic factor with G patch and FHA domains 1 protects retinal vascular endothelial cells under hyperoxia by inhibiting autophagy.
The 3' Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression.
Knockdown of AGGF1 inhibits the invasion and migration of gastric cancer via epithelial-mesenchymal transition through Wnt/β-catenin pathway.
Angiotensin II increases angiogenesis by NF-κB-mediated transcriptional activation of angiogenic factor AGGF1.
circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.
The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.
A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.
Angiogenic factor with G patch and FHA domains 1 (Aggf1) promotes hepatic steatosis in mice.
Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.
Angiogenic factor with G patch and FHA domains 1 (Aggf1) regulates liver fibrosis by modulating TGF-β signaling.
Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease.
Role of microRNA-27a in down-regulation of angiogenic factor AGGF1 under hypoxia associated with high-grade bladder urothelial carcinoma.
Angiogenic factor AGGF1 promotes therapeutic angiogenesis in a mouse limb ischemia model.
Liu X, Shen D, Liu L, Peng Y, Lu Q
Biochemical and biophysical research communications 2024 Jun 18;712-713:149941
Biochemical and biophysical research communications 2024 Jun 18;712-713:149941
Decreased AGGF1 facilitates the progression of placenta accreta spectrum via mediating the P53 signaling pathway under the regulation of miR-1296-5p.
Wang R, Zhao J, Liu C, Li S, Liu W, Cao Q
Reproductive biology 2023 Mar;23(1):100735
Reproductive biology 2023 Mar;23(1):100735
Aggf1 Specifies Hemangioblasts at the Top of Regulatory Hierarchy via Npas4l and mTOR-S6K-Emp2-ERK Signaling.
Yang Z, Guo D, Zhao J, Li J, Zhang R, Zhang Y, Xu C, Ke T, Wang QK
Arteriosclerosis, thrombosis, and vascular biology 2023 Dec;43(12):2348-2368
Arteriosclerosis, thrombosis, and vascular biology 2023 Dec;43(12):2348-2368
Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles.
Zhao J, Xie W, Yang Z, Zhao M, Ke T, Xu C, Li H, Chen Q, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22366
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22366
Neuroprotective effect of AGGF1 against isoflurane-induced cognitive dysfunction in aged rats through activating the PI3K/AKT signaling pathways.
Wu X, Zhang X, Zhao L, Jiang S
Physiology international 2022 Feb 25;
Physiology international 2022 Feb 25;
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells.
Yu Y, Li Y, Peng H, Song Q, Da X, Li H, He Z, Ren X, Xu C, Yao Y, Wang QK
The Journal of biological chemistry 2022 Apr;298(4):101759
The Journal of biological chemistry 2022 Apr;298(4):101759
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
Li R, Yao G, Zhou L, Zhang M, Yan J, Wang X, Li Y
Microvascular research 2021 Nov;138:104230
Microvascular research 2021 Nov;138:104230
AGGF1 inhibits the expression of inflammatory mediators and promotes angiogenesis in dental pulp cells.
Shen S, Shang L, Liu H, Liang Q, Liang W, Ge S
Clinical oral investigations 2021 Feb;25(2):581-592
Clinical oral investigations 2021 Feb;25(2):581-592
Angiogenic factor with G patch and FHA domains 1 protects retinal vascular endothelial cells under hyperoxia by inhibiting autophagy.
Yao G, Li R, Du J, Yao Y
Journal of biochemical and molecular toxicology 2020 Nov;34(11):e22572
Journal of biochemical and molecular toxicology 2020 Nov;34(11):e22572
The 3' Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression.
Ding L, Lu S, Zhou Y, Lyu D, Ouyang C, Ma Z, Lu Q
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1119-1132
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1119-1132
Knockdown of AGGF1 inhibits the invasion and migration of gastric cancer via epithelial-mesenchymal transition through Wnt/β-catenin pathway.
Yao HH, Zhao YJ, He YF, Huang DB, Wang W
Cancer cell international 2019;19:41
Cancer cell international 2019;19:41
Angiotensin II increases angiogenesis by NF-κB-mediated transcriptional activation of angiogenic factor AGGF1.
Si W, Xie W, Deng W, Xiao Y, Karnik SS, Xu C, Chen Q, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Sep;32(9):5051-5062
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Sep;32(9):5051-5062
circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.
He Q, Zhao L, Liu Y, Liu X, Zheng J, Yu H, Cai H, Ma J, Liu L, Wang P, Li Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:331-348
Molecular therapy. Nucleic acids 2018 Mar 2;10:331-348
The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
Yang C, Zheng J, Xue Y, Yu H, Liu X, Ma J, Liu L, Wang P, Li Z, Cai H, Liu Y
Frontiers in molecular neuroscience 2017;10:437
Frontiers in molecular neuroscience 2017;10:437
Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.
Yao Y, Hu Z, Ye J, Hu C, Song Q, Da X, Yu Y, Li H, Xu C, Chen Q, Wang QK
Journal of the American Heart Association 2017 Jun 25;6(6)
Journal of the American Heart Association 2017 Jun 25;6(6)
A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.
Yao Y, Lu Q, Hu Z, Yu Y, Chen Q, Wang QK
Nature communications 2017 Jul 25;8(1):133
Nature communications 2017 Jul 25;8(1):133
Angiogenic factor with G patch and FHA domains 1 (Aggf1) promotes hepatic steatosis in mice.
Shao J, Zeng S, Zhou B, Xu H, Bian Y, Xu Y
Biochemical and biophysical research communications 2017 Jan 1;482(1):134-140
Biochemical and biophysical research communications 2017 Jan 1;482(1):134-140
Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.
Zhou B, Zeng S, Li N, Yu L, Yang G, Yang Y, Zhang X, Fang M, Xia J, Xu Y
Arteriosclerosis, thrombosis, and vascular biology 2017 Apr;37(4):675-684
Arteriosclerosis, thrombosis, and vascular biology 2017 Apr;37(4):675-684
Angiogenic factor with G patch and FHA domains 1 (Aggf1) regulates liver fibrosis by modulating TGF-β signaling.
Zhou B, Zeng S, Li L, Fan Z, Tian W, Li M, Xu H, Wu X, Fang M, Xu Y
Biochimica et biophysica acta 2016 Jun;1862(6):1203-13
Biochimica et biophysica acta 2016 Jun;1862(6):1203-13
Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease.
Lu Q, Yao Y, Hu Z, Hu C, Song Q, Ye J, Xu C, Wang AZ, Chen Q, Wang QK
PLoS biology 2016 Aug;14(8):e1002529
PLoS biology 2016 Aug;14(8):e1002529
Role of microRNA-27a in down-regulation of angiogenic factor AGGF1 under hypoxia associated with high-grade bladder urothelial carcinoma.
Xu Y, Zhou M, Wang J, Zhao Y, Li S, Zhou B, Su Z, Xu C, Xia Y, Qian H, Tu X, Xiao W, Chen X, Chen Q, Wang QK
Biochimica et biophysica acta 2014 May;1842(5):712-25
Biochimica et biophysica acta 2014 May;1842(5):712-25
Angiogenic factor AGGF1 promotes therapeutic angiogenesis in a mouse limb ischemia model.
Lu Q, Yao Y, Yao Y, Liu S, Huang Y, Lu S, Bai Y, Zhou B, Xu Y, Li L, Wang N, Wang L, Zhang J, Cheng X, Qin G, Ma W, Xu C, Tu X, Wang Q
PloS one 2012;7(10):e46998
PloS one 2012;7(10):e46998
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 11889-1-AP(AGGF1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-AGGF1 (IP:11889-1-AP, 3ug; Detection:11889-1-AP 1:500) with mouse liver tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AGGF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AGGF1. This antibody recognizes human,mouse,rat antigen. The AGGF1 antibody has been validated for the following applications: ELISA, WB, IP, IHC analysis.