ZNF197

This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Description

zinc finger protein 197

Protein family

Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Transcription factors

Chromosome

3:p21.31 (44584888 - 44648471)

Ensembl ID

ENSG00000186448  (ver. 84.38)

Orthologs

Mouse Zfp11: ENSMUSG00000051034

UniProt

O14709

neXtProt

NX_O14709

Human splice variants
Mouse splice variants