Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16086-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16086-1-AP, RRID:AB_2181432
- Product name
- RPL23 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPL23 antibody (Cat. #16086-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression.
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance.
Human hematopoietic stem cell vulnerability to ferroptosis.
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Ribosomal Protein L23 Drives the Metastasis of Hepatocellular Carcinoma via Upregulating MMP9.
Triptolide interrupts rRNA synthesis and induces the RPL23‑MDM2‑p53 pathway to repress lung cancer cells.
Proteomics profiling and pathway analysis of hippocampal aging in rhesus monkeys.
Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling.
Altered expression of insulin-degrading enzyme and regulator of calcineurin in the rat intracerebral streptozotocin model and human apolipoprotein E-ε4-associated Alzheimer's disease.
Therapeutic Advantages of Dual Targeting of PPAR-δ and PPAR-γ in an Experimental Model of Sporadic Alzheimer's Disease.
Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease.
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome.
LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.
T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.
Tobacco Smoke Exposure Impairs Brain Insulin/IGF Signaling: Potential Co-Factor Role in Neurodegeneration.
Defective ribosome assembly in Shwachman-Diamond syndrome.
Zhang W, Song X, Jin Z, Zhang Y, Li S, Jin F, Zheng A
Breast cancer research : BCR 2024 Apr 9;26(1):60
Breast cancer research : BCR 2024 Apr 9;26(1):60
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Gong D, Rao X, Min Z, Liu X, Xin H, Zhou P, Yang L, Li D
American journal of cancer research 2023;13(8):3705-3720
American journal of cancer research 2023;13(8):3705-3720
Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance.
Shan L, Xu G, Yao RW, Luan PF, Huang Y, Zhang PH, Pan YH, Zhang L, Gao X, Li Y, Cao SM, Gao SX, Yang ZH, Li S, Yang LZ, Wang Y, Wong CCL, Yu L, Li J, Yang L, Chen LL
Nature 2023 Mar;615(7952):526-534
Nature 2023 Mar;615(7952):526-534
Human hematopoietic stem cell vulnerability to ferroptosis.
Zhao J, Jia Y, Mahmut D, Deik AA, Jeanfavre S, Clish CB, Sankaran VG
Cell 2023 Feb 16;186(4):732-747.e16
Cell 2023 Feb 16;186(4):732-747.e16
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Liu Y, Lai S, He J, Wan J, Fu F, Jinlong Y
Cytotechnology 2022 Jun;74(3):421-432
Cytotechnology 2022 Jun;74(3):421-432
Ribosomal Protein L23 Drives the Metastasis of Hepatocellular Carcinoma via Upregulating MMP9.
Yang M, Zhou Y, Deng H, Zhou H, Cheng S, Zhang D, He X, Mai L, Chen Y, Chen J
Frontiers in oncology 2021;11:779748
Frontiers in oncology 2021;11:779748
Triptolide interrupts rRNA synthesis and induces the RPL23‑MDM2‑p53 pathway to repress lung cancer cells.
Wang J, Zhang ZQ, Li FQ, Chen JN, Gong X, Cao BB, Wang W
Oncology reports 2020 Jun;43(6):1863-1874
Oncology reports 2020 Jun;43(6):1863-1874
Proteomics profiling and pathway analysis of hippocampal aging in rhesus monkeys.
Meng S, Xia W, Pan M, Jia Y, He Z, Ge W
BMC neuroscience 2020 Jan 15;21(1):2
BMC neuroscience 2020 Jan 15;21(1):2
Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling.
Evans HT, Benetatos J, van Roijen M, Bodea LG, Götz J
The EMBO journal 2019 Jul 1;38(13):e101174
The EMBO journal 2019 Jul 1;38(13):e101174
Altered expression of insulin-degrading enzyme and regulator of calcineurin in the rat intracerebral streptozotocin model and human apolipoprotein E-ε4-associated Alzheimer's disease.
Delikkaya B, Moriel N, Tong M, Gallucci G, de la Monte SM
Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Dec;11:392-404
Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Dec;11:392-404
Therapeutic Advantages of Dual Targeting of PPAR-δ and PPAR-γ in an Experimental Model of Sporadic Alzheimer's Disease.
Reich D, Gallucci G, Tong M, de la Monte SM
Journal of Parkinson's disease and Alzheimer's disease 2018 May;5(1)
Journal of Parkinson's disease and Alzheimer's disease 2018 May;5(1)
Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease.
de la Monte SM, Tong M, Schiano I, Didsbury J
Journal of Alzheimer's disease : JAD 2017;55(2):849-864
Journal of Alzheimer's disease : JAD 2017;55(2):849-864
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome.
Qi Y, Li X, Chang C, Xu F, He Q, Zhao Y, Wu L
Scientific reports 2017 May 24;7(1):2323
Scientific reports 2017 May 24;7(1):2323
LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.
Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ
Nature cell biology 2017 Jan;19(1):60-67
Nature cell biology 2017 Jan;19(1):60-67
T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.
Tong M, Deochand C, Didsbury J, de la Monte SM
Journal of Alzheimer's disease : JAD 2016;51(1):123-38
Journal of Alzheimer's disease : JAD 2016;51(1):123-38
Tobacco Smoke Exposure Impairs Brain Insulin/IGF Signaling: Potential Co-Factor Role in Neurodegeneration.
Deochand C, Tong M, Agarwal AR, Cadenas E, de la Monte SM
Journal of Alzheimer's disease : JAD 2016;50(2):373-86
Journal of Alzheimer's disease : JAD 2016;50(2):373-86
Defective ribosome assembly in Shwachman-Diamond syndrome.
Wong CC, Traynor D, Basse N, Kay RR, Warren AJ
Blood 2011 Oct 20;118(16):4305-12
Blood 2011 Oct 20;118(16):4305-12
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 16086-1-AP(RPL23 antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16086-1-AP(RPL23 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RPL23 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPL23. This antibody recognizes human, mouse, rat antigen. The RPL23 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
