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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA026813 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA026813, RRID:AB_1857446
- Product name
- Anti-SPINK2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SPINK2, Gene description: serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor), Alternative Gene Names: HUSI-II, Validated applications: IHC, Uniprot ID: P20155, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Temporary serine protease inhibition and the role of SPINK2 in human bone marrow
SPINK2 Protein Expression Is an Independent Adverse Prognostic Marker in AML and Is Potentially Implicated in the Regulation of Ferroptosis and Immune Response
Mapping human haematopoietic stem cells from haemogenic endothelium to birth
SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes
Barresi V, Di Bella V, Lo Nigro L, Privitera A, Bonaccorso P, Scuderi C, Condorelli D
iScience 2023;26(6):106949
iScience 2023;26(6):106949
SPINK2 Protein Expression Is an Independent Adverse Prognostic Marker in AML and Is Potentially Implicated in the Regulation of Ferroptosis and Immune Response
Pitts H, Cheng C, Cheung J, Sun M, Yung Y, Chan H, Wong R, Yip S, Lau K, Wong W, Raghupathy R, Chan N, Ng M
International Journal of Molecular Sciences 2023;24(11):9696
International Journal of Molecular Sciences 2023;24(11):9696
Mapping human haematopoietic stem cells from haemogenic endothelium to birth
Calvanese V, Capellera-Garcia S, Ma F, Fares I, Liebscher S, Ng E, Ekstrand S, Aguadé-Gorgorió J, Vavilina A, Lefaudeux D, Nadel B, Li J, Wang Y, Lee L, Ardehali R, Iruela-Arispe M, Pellegrini M, Stanley E, Elefanty A, Schenke-Layland K, Mikkola H
Nature 2022;604(7906):534-540
Nature 2022;604(7906):534-540
SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes
Kherraf Z, Christou‐Kent M, Karaouzene T, Amiri‐Yekta A, Martinez G, Vargas A, Lambert E, Borel C, Dorphin B, Aknin‐Seifer I, Mitchell M, Metzler‐Guillemain C, Escoffier J, Nef S, Grepillat M, Thierry‐Mieg N, Satre V, Bailly M, Boitrelle F, Pernet‐Gallay K, Hennebicq S, Fauré J, Bottari S, Coutton C, Ray P, Arnoult C
EMBO Molecular Medicine 2017;9(8):1132-1149
EMBO Molecular Medicine 2017;9(8):1132-1149
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human epididymis and kidney tissues using HPA026813 antibody. Corresponding SPINK2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
