HPA002815

antibody from Atlas Antibodies

Targeting: UQCRC1 D3S3191, QCR1, UQCR1

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA002815

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA002815, RRID:AB_1080486

Product name

Anti-UQCRC1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human UQCRC1, Gene description: ubiquinol-cytochrome c reductase core protein I, Alternative Gene Names: D3S3191, QCR1, UQCR1, Validated applications: WB, IHC, Uniprot ID: P31930, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase.

Elancheliyan P, Maruszczak KK, Serwa RA, Stephan T, Gulgec AS, Borrero-Landazabal MA, Ngati S, Gosk A, Jakobs S, Wasilewski M, Chacinska A
Cell reports 2024 Dec 24;43(12):115038

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C11orf83, a Mitochondrial Cardiolipin-Binding Protein Involved in bc1 Complex Assembly and Supercomplex Stabilization

Desmurs M, Foti M, Raemy E, Vaz F, Martinou J, Bairoch A, Lane L
Molecular and Cellular Biology 2023;35(7):1139-1156

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Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction

Kim M, Serwa R, Samluk L, Suppanz I, Kodroń A, Stępkowski T, Elancheliyan P, Tsegaye B, Oeljeklaus S, Wasilewski M, Warscheid B, Chacinska A
Nature Communications 2023;14(1)

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Ovarian carcinoma immunoreactive antigen–like protein 2 (OCIAD2) is a novel complex III–specific assembly factor in mitochondria

Chojnacka K, Elancheliyan P, Mussulini B, Mohanraj K, Callegari S, Gosk A, Banach T, Góral T, Szczepanowska K, Rehling P, Serwa R, Chacinska A, Ott M
Molecular Biology of the Cell 2022;33(4)

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Isolation and Characterization of Small Extracellular Vesicles from Porcine Blood Plasma, Cerebrospinal Fluid, and Seminal Plasma

Kupcova Skalnikova H, Bohuslavova B, Turnovcova K, Juhasova J, Juhas S, Rodinova M, Vodicka P
Proteomes 2019;7(2):17

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Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7.

Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M, Chacinska A
EMBO molecular medicine 2019 May;11(5)

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NDUFAF5 Hydroxylates NDUFS7 at an Early Stage in the Assembly of Human Complex I

Rhein V, Carroll J, Ding S, Fearnley I, Walker J
Journal of Biological Chemistry 2016;291(28):14851-14860

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Integration of Cardiac Proteome Biology and Medicine by a Specialized Knowledgebase

Zong N, Li H, Li H, Lam M, Jimenez R, Kim C, Deng N, Kim A, Choi J, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu H, Xu T, Weiss J, Duan H, Uhlen M, Yates J, Apweiler R, Ge J, Hermjakob H, Ping P
Circulation Research 2013;113(9):1043-1053

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human heart muscle and lymph node tissues using Anti-UQCRC1 antibody. Corresponding UQCRC1 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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