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- References [19]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18233-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18233-1-AP, RRID:AB_10805765
- Product name
- PDIA6 antibody
- Antibody type
- Polyclonal
- Description
- PDIA6 antibody (Cat. #18233-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ginsenoside Rh2 enhances immune surveillance of natural killer (NK) cells via inhibition of ERp5 in breast cancer.
Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells.
Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.
Venezuelan equine encephalitis virus E1 protein interacts with PDIA6 and PDI inhibition reduces alphavirus production.
COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells.
Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.
A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines.
Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development.
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.
Yang C, Qian C, Zheng W, Dong G, Zhang S, Wang F, Wei Z, Xu Y, Wang A, Zhao Y, Lu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155180
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155180
Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.
Chen Z, Wang S, Pottekat A, Duffey A, Jang I, Chang BH, Cho J, Finck BN, Davidson NO, Kaufman RJ
Molecular metabolism 2024 Feb;80:101874
Molecular metabolism 2024 Feb;80:101874
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Tao S, Yang EJ, Zong G, Mou PK, Ren G, Pu Y, Chen L, Kwon HJ, Zhou J, Hu Z, Khosravi A, Zhang Q, Du Y, Shi WQ, Shim JS
International journal of biological sciences 2023;19(13):4020-4035
International journal of biological sciences 2023;19(13):4020-4035
MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells.
Morimoto Y, Yamashita N, Daimon T, Hirose H, Yamano S, Haratake N, Ishikawa S, Bhattacharya A, Fushimi A, Ahmad R, Takahashi H, Dashevsky O, Mitsiades C, Kufe D
Journal for immunotherapy of cancer 2023 Feb;11(2)
Journal for immunotherapy of cancer 2023 Feb;11(2)
Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.
Aschenbrenner I, Siebenmorgen T, Lopez A, Parr M, Ruckgaber P, Kerle A, Rührnößl F, Catici D, Haslbeck M, Frishman D, Sattler M, Zacharias M, Feige MJ
Journal of molecular biology 2023 Dec 1;435(23):168300
Journal of molecular biology 2023 Dec 1;435(23):168300
Venezuelan equine encephalitis virus E1 protein interacts with PDIA6 and PDI inhibition reduces alphavirus production.
Panny L, Akrhymuk I, Bracci N, Woodson C, Flor R, Elliott I, Zhou W, Narayanan A, Campbell C, Kehn-Hall K
Antiviral research 2023 Apr;212:105560
Antiviral research 2023 Apr;212:105560
COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells.
Xia ZJ, Mahajan S, Paul Daniel EJ, Ng BG, Saraswat M, Campos AR, Murad R, He M, Freeze HH
Frontiers in cell and developmental biology 2022;10:979096
Frontiers in cell and developmental biology 2022;10:979096
Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.
Zhang S, Huang W, Ren L, Ju X, Gong M, Rao J, Sun L, Li P, Ding Q, Wang J, Zhang QC
Cell research 2022 Jan;32(1):9-23
Cell research 2022 Jan;32(1):9-23
A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines.
Mideksa YG, Aschenbrenner I, Fux A, Kaylani D, Weiß CAM, Nguyen TA, Bach NC, Lang K, Sieber SA, Feige MJ
The Journal of biological chemistry 2022 Dec;298(12):102677
The Journal of biological chemistry 2022 Dec;298(12):102677
Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis.
Mestre-Farràs N, Guerrero S, Bley N, Rivero E, Coll O, Borràs E, Sabidó E, Indacochea A, Casillas-Serra C, Järvelin AI, Oliva B, Castello A, Hüttelmaier S, Gebauer F
Nucleic acids research 2022 Aug 12;50(14):8207-8225
Nucleic acids research 2022 Aug 12;50(14):8207-8225
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Chhabra NF, Amend AL, Bastidas-Ponce A, Sabrautzki S, Tarquis-Medina M, Sachs S, Rubey M, Lorenz-Depiereux B, Feuchtinger A, Bakhti M, Lickert H, Przemeck GKH, Hrabě de Angelis M
Molecular metabolism 2021 Dec;54:101334
Molecular metabolism 2021 Dec;54:101334
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
Han C, Jiang YH, Li W, Liu Y
Journal of ethnopharmacology 2021 Apr 6;269:113768
Journal of ethnopharmacology 2021 Apr 6;269:113768
Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development.
Choi JH, Zhong X, Zhang Z, Su L, McAlpine W, Misawa T, Liao TC, Zhan X, Russell J, Ludwig S, Li X, Tang M, Anderton P, Moresco EMY, Beutler B
The Journal of experimental medicine 2020 Apr 6;217(4)
The Journal of experimental medicine 2020 Apr 6;217(4)
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Jang I, Pottekat A, Poothong J, Yong J, Lagunas-Acosta J, Charbono A, Chen Z, Scheuner DL, Liu M, Itkin-Ansari P, Arvan P, Kaufman RJ
eLife 2019 Jun 11;8
eLife 2019 Jun 11;8
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G
Cancer cell 2019 Feb 11;35(2):204-220.e9
Cancer cell 2019 Feb 11;35(2):204-220.e9
Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.
Samanta S, Tamura S, Dubeau L, Mhawech-Fauceglia P, Miyagi Y, Kato H, Lieberman R, Buckanovich RJ, Lin YG, Neamati N
Oncotarget 2017 Nov 28;8(61):103543-103556
Oncotarget 2017 Nov 28;8(61):103543-103556
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gao H, Sun B, Fu H, Chi X, Wang F, Qi X, Hu J, Shao S
Oncotarget 2016 Aug 16;7(33):53289-53298
Oncotarget 2016 Aug 16;7(33):53289-53298
The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.
Zhu Z, Xu W, Dai J, Chen X, Zhao X, Fang P, Yang F, Tang M, Wang Z, Wang L, Ma D, Qaio Z
The international journal of biochemistry & cell biology 2013 Mar;45(3):571-82
The international journal of biochemistry & cell biology 2013 Mar;45(3):571-82
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 18233-1-AP(PDIA6 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach using 18233-1-AP(PDIA6 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDIA6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PDIA6. This antibody recognizes human, mouse, rat antigen. The PDIA6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
