11-8023-25

antibody from ABEOMICS Inc.
Targeting: CRHR2 CRF-RB, CRF2, HM-CRF
Provider product page for 11-8023-25

Antibody data

Product number
11-8023-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-CRHR2 Antibody
Antibody type
Polyclonal
Description
CRHR2 (CRF2R, CRH2R) (corticotropin releasing hormone receptor 2) belongs to the G-protein coupled receptor 2 family. This receptor has high affinity for corticotropin releasing hormone (CRH) and may also bind to CRH-related peptides, such as, urocortin. The human CRHR2 gene contains 12 exons. Three major functional isoforms have been reported: alpha, beta and gamma encoded by transcripts with alternative first exons which differ from each other by signal sequence and extra-cellular domain. CRH is synthesized in the hypothalamus and plays an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge. CRHR2 has high expression in brain, caudate nucleus, cerebrum, colon, endometrium, etc.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant CRHR2
protein (amino acids 1-200) was use
d as the immunogen for this antibod
y.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
CRHR2 protein structure - 11-8023-25 shown in red.