Antibody data
- Antibody Data
- Antigen structure
- References [29]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15066-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15066-1-AP, RRID:AB_2151109
- Product name
- NDUFS3 antibody
- Antibody type
- Polyclonal
- Description
- NDUFS3 antibody (Cat. #15066-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aging-Related Mitochondrial Dysfunction Is Associated With Fibrosis in Benign Prostatic Hyperplasia.
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells.
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
Exercise and Doxorubicin Modify Markers of Iron Overload and Cardiolipin Deficiency in Cardiac Mitochondria.
Increased COX-1 expression in benign prostate epithelial cells is triggered by mitochondrial dysfunction.
NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.
A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H(2)S oxidation.
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice.
SR18292 exerts potent antitumor effects in multiple myeloma via inhibition of oxidative phosphorylation.
Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.
Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants.
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts.
The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.
Proteomic analysis indicates that mitochondrial energy metabolism in skeletal muscle tissue is negatively correlated with feed efficiency in pigs.
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.
COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency.
The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex I.
AIF inhibits tumor metastasis by protecting PTEN from oxidation.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Quantitative proteomics reveals olfactory input-dependent alterations in the mouse olfactory bulb proteome.
Telmisartan improves kidney function through inhibition of the oxidative phosphorylation pathway in diabetic rats.
Gene expression profiling in glomeruli of diabetic nephropathy rat.
Apoptosis-inducing factor is a target gene of C/EBPα and participates in adipocyte differentiation.
Adrian AE, Liu TT, Pascal LE, Bauer SR, DeFranco DB, Ricke WA
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Jun 1;79(6)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Jun 1;79(6)
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Zhu Y, Huang H, Chen Z, Tao Y, Liao LY, Gao SH, Wang YJ, Gao CY
Neuroscience bulletin 2024 Feb;40(2):182-200
Neuroscience bulletin 2024 Feb;40(2):182-200
Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells.
Baleva MV, Piunova U, Chicherin I, Vasilev R, Levitskii S, Kamenski P
International journal of molecular sciences 2023 Dec 20;25(1)
International journal of molecular sciences 2023 Dec 20;25(1)
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
He JY, Li DD, Wen Q, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
Exercise and Doxorubicin Modify Markers of Iron Overload and Cardiolipin Deficiency in Cardiac Mitochondria.
Montalvo RN, Boeno FP, Dowllah IM, Moritz CEJ, Nguyen BL, Doerr V, Bomkamp MP, Smuder AJ
International journal of molecular sciences 2023 Apr 22;24(9)
International journal of molecular sciences 2023 Apr 22;24(9)
Increased COX-1 expression in benign prostate epithelial cells is triggered by mitochondrial dysfunction.
Hudson CN, He K, Pascal LE, Liu T, Myklebust LK, Dhir R, Srivastava P, Yoshimura N, Wang Z, Ricke WA, DeFranco DB
American journal of clinical and experimental urology 2022;10(4):234-245
American journal of clinical and experimental urology 2022;10(4):234-245
NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.
Santana-Codina N, Del Rey MQ, Kapner KS, Zhang H, Gikandi A, Malcolm C, Poupault C, Kuljanin M, John KM, Biancur DE, Chen B, Das NK, Lowder KE, Hennessey CJ, Huang W, Yang A, Shah YM, Nowak JA, Aguirre AJ, Mancias JD
Cancer discovery 2022 Sep 2;12(9):2180-2197
Cancer discovery 2022 Sep 2;12(9):2180-2197
A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H(2)S oxidation.
Kumar R, Landry AP, Guha A, Vitvitsky V, Lee HJ, Seike K, Reddy P, Lyssiotis CA, Banerjee R
The Journal of biological chemistry 2022 Jan;298(1):101435
The Journal of biological chemistry 2022 Jan;298(1):101435
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
Xiong W, Yuan Z, Wang T, Wu S, Xiong Y, Yao Y, Yang Y, Wu H
Frontiers in pharmacology 2021;12:586010
Frontiers in pharmacology 2021;12:586010
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
Jin X, Zhang J, Yi Q, Meng F, Yu J, Ji Y, Mo JQ, Tong Y, Jiang P, Guan MX
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
Jin X, Zhang Z, Nie Z, Wang C, Meng F, Yi Q, Chen M, Sun J, Zou J, Jiang P, Guan MX
The Journal of biological chemistry 2021 Jan-Jun;296:100437
The Journal of biological chemistry 2021 Jan-Jun;296:100437
DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice.
Xu X, Wang W, Wang Z, Lv J, Xu X, Xu J, Yang J, Zhu X, Lu Y, Duan W, Huang X, Wang J, Zhou J, Shen X
Diabetes 2020 Sep;69(9):1974-1988
Diabetes 2020 Sep;69(9):1974-1988
SR18292 exerts potent antitumor effects in multiple myeloma via inhibition of oxidative phosphorylation.
Xiang Y, Fang B, Liu Y, Yan S, Cao D, Mei H, Wang Q, Hu Y, Guo T
Life sciences 2020 Sep 1;256:117971
Life sciences 2020 Sep 1;256:117971
Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.
Weber RA, Yen FS, Nicholson SPV, Alwaseem H, Bayraktar EC, Alam M, Timson RC, La K, Abu-Remaileh M, Molina H, Birsoy K
Molecular cell 2020 Feb 6;77(3):645-655.e7
Molecular cell 2020 Feb 6;77(3):645-655.e7
Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants.
Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM
JCI insight 2018 Nov 2;3(21)
JCI insight 2018 Nov 2;3(21)
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
Papadopoulos N, Lennartsson J, Heldin CH
The Journal of cell biology 2018 May 7;217(5):1701-1717
The Journal of cell biology 2018 May 7;217(5):1701-1717
Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts.
Li H, Zhao H, Hao S, Shang L, Wu J, Song C, Meyron-Holtz EG, Qiao T, Li K
Scientific reports 2018 Mar 23;8(1):5118
Scientific reports 2018 Mar 23;8(1):5118
The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.
Purandare N, Somayajulu M, Hüttemann M, Grossman LI, Aras S
The Journal of biological chemistry 2018 Apr 27;293(17):6517-6529
The Journal of biological chemistry 2018 Apr 27;293(17):6517-6529
Proteomic analysis indicates that mitochondrial energy metabolism in skeletal muscle tissue is negatively correlated with feed efficiency in pigs.
Fu L, Xu Y, Hou Y, Qi X, Zhou L, Liu H, Luan Y, Jing L, Miao Y, Zhao S, Liu H, Li X
Scientific reports 2017 Mar 27;7:45291
Scientific reports 2017 Mar 27;7:45291
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Aras S, Arrabi H, Purandare N, Hüttemann M, Kamholz J, Züchner S, Grossman LI
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.
Tang H, Li J, Liu X, Wang G, Luo M, Deng H
Scientific reports 2016 Jun 21;6:28388
Scientific reports 2016 Jun 21;6:28388
COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency.
Martinez Lyons A, Ardissone A, Reyes A, Robinson AJ, Moroni I, Ghezzi D, Fernandez-Vizarra E, Zeviani M
Journal of medical genetics 2016 Dec;53(12):846-849
Journal of medical genetics 2016 Dec;53(12):846-849
The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex I.
Su CY, Chang YC, Yang CJ, Huang MS, Hsiao M
Scientific reports 2016 Aug 12;6:31357
Scientific reports 2016 Aug 12;6:31357
AIF inhibits tumor metastasis by protecting PTEN from oxidation.
Shen SM, Guo M, Xiong Z, Yu Y, Zhao XY, Zhang FF, Chen GQ
EMBO reports 2015 Nov;16(11):1563-80
EMBO reports 2015 Nov;16(11):1563-80
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
Quantitative proteomics reveals olfactory input-dependent alterations in the mouse olfactory bulb proteome.
Zeng HL, Rao X, Zhang LK, Zhao X, Zhang WP, Wang J, Xu F, Guo L
Journal of proteomics 2014 Sep 23;109:125-42
Journal of proteomics 2014 Sep 23;109:125-42
Telmisartan improves kidney function through inhibition of the oxidative phosphorylation pathway in diabetic rats.
Zhang Q, Xiao X, Li M, Li W, Yu M, Zhang H, Sun X, Mao L, Xiang H
Journal of molecular endocrinology 2012 Aug;49(1):35-46
Journal of molecular endocrinology 2012 Aug;49(1):35-46
Gene expression profiling in glomeruli of diabetic nephropathy rat.
Zhang Q, Xiao X, Li M, Li W, Yu M, Zhang H, Sun X, Mao L, Xiang H
Experimental biology and medicine (Maywood, N.J.) 2012 Aug;237(8):903-11
Experimental biology and medicine (Maywood, N.J.) 2012 Aug;237(8):903-11
Apoptosis-inducing factor is a target gene of C/EBPα and participates in adipocyte differentiation.
Shen SM, Yu Y, Wu ZX, Zheng Y, Chen GQ, Wang LS
FEBS letters 2011 Jul 21;585(14):2307-12
FEBS letters 2011 Jul 21;585(14):2307-12
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 15066-1-AP(NDUFS3 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NDUFS3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NDUFS3. This antibody recognizes human,mouse,rat antigen. The NDUFS3 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15066-1-AP(NDUFS3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15066-1-AP(NDUFS3 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue